Tag: M.W=50-100

Gajare, Vikas S. published the artcileDiversity oriented concise asymmetric synthesis of azasugars: a facile access to L-2,3-trans-3,4-cis-dihydroxyproline and (3S,5S)-3,4,5-trihydroxypiperidine, Name: (R)-Oxiran-2-ylmethanol, the publication is Tetrahedron Letters (2015), 56(48), 6659-6663, database is CAplus.

Diversity oriented concise asym. syntheses of L-2,3-trans-3,4-cis-dihydroxyproline and (3S,5S)-3,4,5-trihydroxypiperidine have been developed from (R)-glycidol. The key step of the synthesis is Sharpless asym. dihydroxylation on enantiomerically pure TBDMS protected allylic alc. I which generates the triol intermediate II in excellent de. The (2R,3R,4S)-2,3-dihydroxypentanoate derivative II was subsequently converted to natural pyrrolidine azasugar L-2,3-trans-3,4-cis-dihydroxyproline and non-natural piperidine azasugar III under cascade reaction conditions in good yields.

Tetrahedron Letters published new progress about 57044-25-4. 57044-25-4 belongs to alcohols-buliding-blocks, auxiliary class Epoxides,Chiral,Aliphatic hydrocarbon chain,Alcohol, name is (R)-Oxiran-2-ylmethanol, and the molecular formula is C3H6O2, Name: (R)-Oxiran-2-ylmethanol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Gajare, Vikas S. published the artcileA concise stereoselective synthesis of (+)-1-deoxy-6-epi-castanospermine, SDS of cas: 57044-25-4, the publication is Tetrahedron Letters (2016), 57(13), 1486-1488, database is CAplus.

A concise stereoselective synthesis of (+)-1-deoxy-6-epi-castanospermine has been developed through stereoselective approach from the chiral precursor R-glycidol. The key steps in the synthesis involve Grignard reaction through Weinreb amide, followed by Sharpless dihydroxylation and stereoselective reduction of imine assigned the required stereochem. feature of indolizidine azasugar (+)-1-deoxy-6-epi-castanospermine.

Tetrahedron Letters published new progress about 57044-25-4. 57044-25-4 belongs to alcohols-buliding-blocks, auxiliary class Epoxides,Chiral,Aliphatic hydrocarbon chain,Alcohol, name is (R)-Oxiran-2-ylmethanol, and the molecular formula is C3H6O2, SDS of cas: 57044-25-4.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Nikishin, G. I. published the artcileOxidative splitting of 1-methylcycloalkanols by the lead(IV) acetate-copper(II) acetate system, Related Products of alcohols-buliding-blocks, the publication is Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya (1979), 1548-53, database is CAplus.

Oxidative cleavage of title alcs. I (n = 1-4) with Pb(OAc)₄-Cu(OAc)₂ gave 76-99% MeCO(CH₂)_nCH:CH₂ with 20-49% I conversion via the intermediate MeCO(CH₂)_n+2â€?radical. The reactivity of I decreased in the order of n 1 > 2 > 4 > 3.

Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya published new progress about 20117-47-9. 20117-47-9 belongs to alcohols-buliding-blocks, auxiliary class Aliphatic cyclic hydrocarbon,Alcohol, name is 1-Methylcyclobutan-1-ol, and the molecular formula is C5H10O, Related Products of alcohols-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Matsuda, Yutaka published the artcileSynthetic studies on polymaxenolides: model studies for constructing dihydropyran portion and synthesis of lower portion, HPLC of Formula: 57044-25-4, the publication is Tetrahedron (2014), 70(6), 1154-1168, database is CAplus.

With a goal of the total synthesis of polymaxenolide, the first hybrid marine natural product, the model studies for constructing the dihydropyran portion based on the originally proposed biosynthesis (C-C bond formation followed by dehydrative cyclization) and the synthesis of the lower portion (the C1-C3, C7-C17 portion) based on an iodide-induced Morita-Baylis-Hillman type reaction (a three-component assembly) followed by Suzuki-Miyaura cross-coupling are described.

Tetrahedron published new progress about 57044-25-4. 57044-25-4 belongs to alcohols-buliding-blocks, auxiliary class Epoxides,Chiral,Aliphatic hydrocarbon chain,Alcohol, name is (R)-Oxiran-2-ylmethanol, and the molecular formula is C3H6O2, HPLC of Formula: 57044-25-4.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Meinert, Cornelia published the artcileAnisotropy spectroscopy of chiral alcohols, amines, and monocarboxylic acids: Implications for the analyses of extraterrestrial samples, Recommanded Product: (R)-Oxiran-2-ylmethanol, the publication is Journal of Photochemistry and Photobiology, A: Chemistry (2016), 130-137, database is CAplus.

Stereoisomers of distinct chiral amino acids were observed to occur in L-enantioenriched form in carbonaceous chondrite meteorites. Meteoritic amines and monocarboxylic acids were recently shown to occur in racemic ratio. In this study we investigated the electronic CD and anisotropy spectra of chiral alcs., chiral amines, and chiral monocarboxylic acids. We recorded CD and anisotropy spectra from 280 to 170 nm in aqueous solution using a synchrotron-radiation UV CD spectrophotometer. The obtained anisotropy spectra are employed to discuss the likely role of UV circularly polarized light leading to enantioenriched amino acids, as well as racemic amines and monocarboxylic acids during their primordial interstellar synthesis. These data will moreover accompany the European Space Agency’s Rosetta mission, which successfully landed Philae on the nucleus of comet 67P/Churyumov-Gerasimenko to search for chiral organic mols.

Journal of Photochemistry and Photobiology, A: Chemistry published new progress about 57044-25-4. 57044-25-4 belongs to alcohols-buliding-blocks, auxiliary class Epoxides,Chiral,Aliphatic hydrocarbon chain,Alcohol, name is (R)-Oxiran-2-ylmethanol, and the molecular formula is C3H6O2, Recommanded Product: (R)-Oxiran-2-ylmethanol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Andringa, Ruben L. H. published the artcileSynthesis of phosphatidic acids via cobalt(salen) catalyzed epoxide ring-opening with dibenzyl phosphate, Application In Synthesis of 57044-25-4, the publication is Organic & Biomolecular Chemistry (2022), 20(11), 2200-2204, database is CAplus and MEDLINE.

With a CoIII(salen)OTs catalyst, dibenzyl phosphate ring-opens a variety of terminal epoxides with excellent regio-selectively and yields up to 85%. The reaction is used in a highly efficient synthesis of enantiopure mixed-diacyl phosphatidic acids, including a photoswitchable phosphatidic acid mimic.

Organic & Biomolecular Chemistry published new progress about 57044-25-4. 57044-25-4 belongs to alcohols-buliding-blocks, auxiliary class Epoxides,Chiral,Aliphatic hydrocarbon chain,Alcohol, name is (R)-Oxiran-2-ylmethanol, and the molecular formula is C3H6O2, Application In Synthesis of 57044-25-4.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Zhang, Quan published the artcileCarboalumination-epoxide ring opening for the formation of 1,4-disubstituted (Z)-3,6-alkadienols, Related Products of alcohols-buliding-blocks, the publication is Chinese Journal of Chemistry (2013), 31(6), 773-778, database is CAplus.

Allylalumination of alkynes, i.e. forming Negishi’s (Z)-alkenyl dialkylalane, followed by alkenylation of epoxides provides 1,4-disubstituted (Z)-3,6-alkadienols. The alkenylation can be facilitated by the presence of a neighboring coordinating group in the epoxides. This “one-pot” approach was successfully applied in the large-scale production of the C(10)-C(15) fragment of 9,10-dehydroepothilone D, a synthetic epothilone analog as an anticancer agent in phase-2 clin. trials.

Chinese Journal of Chemistry published new progress about 57044-25-4. 57044-25-4 belongs to alcohols-buliding-blocks, auxiliary class Epoxides,Chiral,Aliphatic hydrocarbon chain,Alcohol, name is (R)-Oxiran-2-ylmethanol, and the molecular formula is C3H5BN2O2, Related Products of alcohols-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Skvorcova, M. published the artcileIntramolecular cyclopropylmethylation via non-classical carbocations, Formula: C3H6O2, the publication is Organic & Biomolecular Chemistry (2017), 15(33), 6909-6912, database is CAplus and MEDLINE.

Cyclopropyl-cyclopropyl rearrangement was achieved selectively by intramol. trapping of cyclopropylmethyl carbenium ions with an internal nucleophile. This was exploited as a useful method for the introduction of a cyclopropyl group into complex mols. using readily accessible disubstituted cyclopropane intermediates.

Organic & Biomolecular Chemistry published new progress about 57044-25-4. 57044-25-4 belongs to alcohols-buliding-blocks, auxiliary class Epoxides,Chiral,Aliphatic hydrocarbon chain,Alcohol, name is (R)-Oxiran-2-ylmethanol, and the molecular formula is C4H6O3, Formula: C3H6O2.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Brunet, Ernesto published the artcileThe use of lanthanide luminescence as a reporter in the solid state: Desymmetrization of the prochiral layers of γ-zirconium phosphate/phosphonate and circularly polarized luminescence, Application In Synthesis of 57044-25-4, the publication is Microporous and Mesoporous Materials (2013), 222-234, database is CAplus and MEDLINE.

Solid-state CPL measurements were performed for the first time on hybrid, laminar materials based on γ-ZrP pillared with organic diphosphonates. Ad hoc optically pure diphosphonates (I) were synthesized and the luminescence properties of their complexation with Tb(III) were verified in solution CD and CPL measurements showed that the bistriazolylpyridine chromophores bonded to the metal provided an effective chiral environment that produced significant signals. In the case of the γ-ZrP-derived materials, exptl. evidence and simple mol. modeling hinted to the occurrence of supramol. chirality in the particles, induced by the intrinsic dissymmetry of the organic diphosphonates or by the intercalation of chiral species such as 1-phenethylamine. Chirality at the supramol. level was revealed in the solid state by the CPL signals measured from reporter Tb(III) ions intercalated in the hybrid matrix.

Microporous and Mesoporous Materials published new progress about 57044-25-4. 57044-25-4 belongs to alcohols-buliding-blocks, auxiliary class Epoxides,Chiral,Aliphatic hydrocarbon chain,Alcohol, name is (R)-Oxiran-2-ylmethanol, and the molecular formula is C3H6O2, Application In Synthesis of 57044-25-4.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Kim, Jungjoon published the artcileFlexible Tetrahydropyran Synthesis from Homopropargylic Alcohols Using Sequential Pd-Au Catalysis, Application of (R)-Oxiran-2-ylmethanol, the publication is Organic Letters (2017), 19(1), 242-245, database is CAplus and MEDLINE.

A flexible synthetic method toward highly substituted tetrahydropyran is reported. The key transformation involves atom-efficient sequential metal catalysis consisting of Pd-catalyzed addition of homopropargylic alcs. to alkoxyallene and the subsequent gold(I)-catalyzed cycloisomerization. Notably, this method gives access to both 2,6-cis- and 2,6-trans-tetrahydropyrans, e.g., I, possessing diverse substitution patterns.

Organic Letters published new progress about 57044-25-4. 57044-25-4 belongs to alcohols-buliding-blocks, auxiliary class Epoxides,Chiral,Aliphatic hydrocarbon chain,Alcohol, name is (R)-Oxiran-2-ylmethanol, and the molecular formula is C3H6O2, Application of (R)-Oxiran-2-ylmethanol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts