Tag: M.W=400-500

Liu, Wanjing published the artcileNovel UV-curable epoxy resins modified with alkyne: Cured through thiol-yne click reaction, Recommanded Product: Pentaerythritol tetra(3-mercaptopropionate), the main research area is UV curable epoxy resin alkyne thiol yne click reaction; photocrosslinking dynamic thermal dielec phys property.

With the development of light-curing resin inks, various types of unsaturated resins modified with alkene have been reported in recent years. In this present work, however, the use of reactive monomers containing carbon-carbon triple bonds to react with epoxy resin was proposed to synthesize unsaturated resins modified with alkyne, and then to explore the potential applicability of alkyne groups in photocurable resins. Therefore, propargylic acid and 2-butynoic acid were resp. used to introduce unsaturation by ring-opening reaction with epoxy groups, while the hydroxyl groups generated by previous reaction were used to introduce carboxyl groups by reaction with 1,2,5,6-tetrahydrophthalic anhydride to obtain the final alkyne-modified resins. Considering the highly efficient reactivity of thiol-yne click chem., the triple bond conversion of photocurable resins with and without thiol addition were prepared and compared to investigate the photosensitivity of them. It was found that resins modified with propargylic acid showed more photosensitivity and resins with thiol addition exhibited excellent triple bond conversion (the highest is nearly 100 %), meanwhile, in this study, thermal and dielec. properties of two alkyne-modified resins with different component additions were also tested and discussed.

Progress in Organic Coatings published new progress about Click chemistry. 7575-23-7 belongs to class alcohols-buliding-blocks, name is Pentaerythritol tetra(3-mercaptopropionate), and the molecular formula is C17H28O8S4, Recommanded Product: Pentaerythritol tetra(3-mercaptopropionate).

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Wang, Zhengyue published the artcileUV-curable self-healing polyurethane coating based on thiol-ene and Diels-Alder double click reactions, COA of Formula: C17H28O8S4, the main research area is polyurethane acrylate UV curable self healing coating click reaction.

Endowing UV-curable coatings with self-healing properties by incorporating dynamic bonds into their crosslinking network is of vital significance. However, in practical applications, self-healing polymers are often plagued with problems such as a high healing temperature and long healing time. To address this challenge, we developed a new type of UV-curable polyurethane coating by the combination of Diels-Alder and thiol-ene click reactions. The Diels-Alder bonds in the polyurethane samples developed in this work furnished perfect mech. properties and self-healing ability. Self-healing of polyurethane based on Diels-Alder bonds usually occurs at 120°C. Thiol-ene click reaction is a robust, novel polymerization method, and it improved the structural performance of the polymer with a more homogeneous structure being formed than that achieved with traditional UV-curing. Herein, a novel UV-curable self-healing coating, which is referred to as a PU-SH system, was designed by integrating thiol-ene into polyurethane resins containing Diels-Alder bonds. Results of analyses by assorted techniques (including Fourier-transform IR spectroscopy, different scanning calorimetry, rheol., optical microscopy, and 3D optical interferometric profilometry) strongly indicated that the self-healing ability of the prepared coatings is superior to those of previously studied traditional UV-curing coatings, which are referred to as PU systems. The resultant coatings of the PU-SH system showed a remarkable reduction in the healing temperature from 120°C for the PU system to 90°C. The rapid scratch-healing properties of the UV-curable coatings, taken together with the moderate healing temperature makes the material attractive for a variety of applications, such as in flexible electronic screens, car paint film, and aircraft interior finishes.

Progress in Organic Coatings published new progress about Click chemistry. 7575-23-7 belongs to class alcohols-buliding-blocks, name is Pentaerythritol tetra(3-mercaptopropionate), and the molecular formula is C17H28O8S4, COA of Formula: C17H28O8S4.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Jia, Yaya published the artcileHigh refractive index polythiourethane networks with high mechanical property via thiol-isocyanate click reaction, Computed Properties of 7575-23-7, the main research area is polythiourethane thiol isocyanate click reaction refractive index.

High refractive index polymers (HRIPs), especially sulfur-containing HRIPs, play an important role in optical materials; particularly the thermosetting sulfur-containing polyurethane is widely used in optical lenses. To understand the effect of thiol and isocyanate structures on thermosetting polythiourethane properties, a comprehensive study of the basic thermal, optical and mech. properties of the obtained polythiourethane network structure was conducted, which results indicated that in addition to functionality and the presence of rigid groups affect the glass transition temperature, the conjugation effect and steric hindrance effect in the structure can also cause more changes in the glass transition temperature All polythiourethane materials formed uniform and densely crosslinked network structures. Due to the introduction of highly polarizable sulfur atoms in 2,3-bis((2-mercaptoethyl)thio)-1-propanethiol (GST) and benzene rings in bis(isocyanatomethyl)benzene (XDI), the resulting polythiourethanes exhibited a high refractive index of 1.6559 (589 nm) and a tensile strength of 95.64 MPa while the Abbe’s number was 33.24, fully meeting the lens requirements. The important structure-property relationships of polythiourethane will be helpful for the rational design of HRIPs.

Polymer published new progress about Click chemistry. 7575-23-7 belongs to class alcohols-buliding-blocks, name is Pentaerythritol tetra(3-mercaptopropionate), and the molecular formula is C17H28O8S4, Computed Properties of 7575-23-7.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Zhang, Jiancheng published the artcilePreparation of novel UV-cured methacrylate hybrid materials with high thermal stability via thiol-ene photopolymerization, COA of Formula: C17H28O8S4, the main research area is POSS methacrylate thiol ene click reaction photocuring thermomech property.

Methacryloxypropyl-polyhedral oligomeric silsesquioxane (MAP-POSS) was photopolymerized with the tri- or tetra-functional thiol monomer in different stoichiometry. A novel inorganic-organic methacrylate hybrid material with highly cross-linked network and high performance was synthesized by UV-initiated thiol-ene click chem. SEM-EDAX images and XRD diffractograms showed that no agglomeration of MAP-POSS was observed, indicating MAP-POSS dispersed uniformly in the hybrid materials. Real-time FTIR was employed to monitor the conversion of thiol and methacrylate as a function of irradiation time, and highly thiolated monomer could promote the conversion of methacrylate effectively because of stronger chain propagation capability. The TGA indicated that the hybrid materials had high thermal stability of which the onset decomposition temperature rose to 350°, ∼50° higher than that of the traditional UV-cured epoxy acrylate/triethylene glycol dimethacrylate (EA/TEGDMA, 70:30 weight/weight) resin. The highest glass transition temperature (Tg) of the hybrid materials was 76.2°. Compared with traditional EA/TEGDMA resins, the novel hybrid materials consisted of MAP-POSS had fast curing rate, high mech. properties and thermal stability which made the wider practical applications of UV-cured hybrid materials feasible.

Journal of Materials Science published new progress about Click chemistry. 7575-23-7 belongs to class alcohols-buliding-blocks, name is Pentaerythritol tetra(3-mercaptopropionate), and the molecular formula is C17H28O8S4, COA of Formula: C17H28O8S4.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Arslan, Mustafa published the artcileFunctionalization of Poly(oxindole biphenylylene) membranes by photoinduced thiol-yne click chemistry, Quality Control of 7575-23-7, the main research area is polyoxindole biphenylylene membrane functionalization photoinduced click chem property.

The modification of poly(oxindole biphenylylene) (POXI) membranes by photoinduced thiol-yne click approach is presented. Initially, a propargyl-functionalized porous poly(oxindole biphenylylene) (POXI-PG) membrane was prepared by condensation reaction of isatin and aromatic hydrocarbons with a superacid-catalyst. Subsequently, the solution and surface functionalization of POXI-PG by one-step photoinitiated thiol-yne click reaction with various thiol functional mols., namely pentaerythritol tetrakis(3-mercaptopropionate) (PETMP), 1,2-ethanedithiol (EDT) and thiol modified poly(ethylene glycol) Me ether (PEG-SH) was demonstrated. The spectral and thermal investigations via FT-IR, 1H NMR, XPS and DSC analyses confirmed the success of the modification process. The POXI-PG membranes crosslinked with PETMP had the mol. weight cut off (MWCO) reduced from 75 to 5 kg mol-1. They became stable in different organic solvents with permeations between 0.4 and 2.8 L m-2 h-1 bar-1.

Journal of Membrane Science published new progress about Click chemistry. 7575-23-7 belongs to class alcohols-buliding-blocks, name is Pentaerythritol tetra(3-mercaptopropionate), and the molecular formula is C17H28O8S4, Quality Control of 7575-23-7.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Luo, Guanzhou published the artcileFacile fabrication of an F-POSS polymer-based liquid-repellent Cu mesh with excellent durability and self-cleaning performance, Recommanded Product: Pentaerythritol tetra(3-mercaptopropionate), the main research area is octavinyl polyhedral oligomeric silsesquioxane copper polymer durability.

A facile method that combines alkali-assisted oxidation and -SH chelation with a click chem. reaction was employed to create an F-POSS polymer surface (fluorinated octavinyl polyhedral oligomeric silsesquioxane polymer)-based Cu mesh (F-POSS-OM). The as-prepared F-POSS-OM surface displayed a cohering hierarchical nano-F-POSS polymer granule/micro-Cu(OH)2 wire structure, which provided a re-entrant geometry needed for liquid-repellency and low liquid sliding angles (<15°). Moreover, the easy-prepared structure endows the F-POSS-OM with remarkable durability for mech. and chem. damages, including wear abrasion, tape-peeling, 100 cm-height hammer impact, severe hand twisting, strong acid/base/salt solutions, and high temperatures Importantly, F-POSS-OM still retained excellent self-cleaning performance even after being subjected to these damages. Soft Matter published new progress about Click chemistry. 7575-23-7 belongs to class alcohols-buliding-blocks, name is Pentaerythritol tetra(3-mercaptopropionate), and the molecular formula is C17H28O8S4, Recommanded Product: Pentaerythritol tetra(3-mercaptopropionate).

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Sharma, Sadhana published the artcileThe effects of processing variables on electrospun poly(ethylene glycol) fibrous hydrogels formed from the thiol-norbornene click reaction, Synthetic Route of 7575-23-7, the main research area is PEG norbornene PEO I2959click reaction tissue engineering shear modulus.

Electrospinning has been used to create scaffolds with tunable micro/nano architecture, stiffness, and porosity to mimic native extracellular matrix. This study investigated the effects of electrospinning parameters and hydrogel formulation (solvent and crosslinker type) on the architecture and properties of fibrous poly(ethylene glycol) (PEG) hydrogels formed from a photoclick thiol-norbornene reaction. Fibrous hydrogels were prepared using hydrogel precursors (four-arm PEG norbornene and multi-thiol crosslinker), sacrificial poly(ethylene oxide) (PEO, 400 kDa), and photoinitiator (I2959) in either 2,2-triflouroethanol (TFE) or water. Three thiol crosslinkers- 2,2′-(ethylenedioxy)diethanethiol (EDT), pentaerythritol tetrakis(3mercaptopropionate) (PTMP), and PEG dithiol (PEGDT)- were investigated. Fibrous PEG networks with uniform fibers were produced at applied voltages of 10 or 12 kV for TFE and 16 kV for water. Fiber diameters of electrospun hydrogels were largely affected by the solvent when combined with PEO concentration and ranged from 0.5 to 3.5 mm in dry state. While the effect of crosslinker type on fiber diameter, morphol., and porosity of the fibrous hydrogel was minimal, it did modulate its shear modulus. To this end, this study provides the groundwork for selecting processing parameters to achieve desired properties of fibrous PEG thiol-norbornene hydrogels for intended tissue engineering applications ranging from neural, cardiovascular to musculoskeletal.

Journal of Applied Polymer Science published new progress about Click chemistry. 7575-23-7 belongs to class alcohols-buliding-blocks, name is Pentaerythritol tetra(3-mercaptopropionate), and the molecular formula is C17H28O8S4, Synthetic Route of 7575-23-7.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Gablier, Alexandra published the artcileTransesterification in Epoxy-Thiol Exchangeable Liquid Crystalline Elastomers, Safety of Pentaerythritol tetra(3-mercaptopropionate), the main research area is transesterification epoxy thiol exchangeable liquid crystalline elastomer.

The incorporation of vitrimer bond-exchange chem. into liquid crystalline elastomer networks produces “”exchangeable liquid crystal elastomers”” (xLCE). These materials offer a facile method of material reshaping and alignment post-polymerization via the application of a mech. stress above the temperature of activation of bond exchange. We use diepoxy mesogenic monomers with thiol-terminated spacers and crosslinker to investigate a range of resulting xLCE. The “”click”” chem. of thiols results in good control over the network topol. and low glass transition in this family of materials. By combining different spacers, we were able to obtain smectic and nematic phases and adjust the liquid crystal to the isotropic phase transition between 42 and 140°C, while the elastic-plastic transition temperature was maintained close to 200°C. The broad gap between these temperatures ensures that thermally actuating uniformly aligned elastomers are stable and show no residual plastic creep, making epoxy-thiol xLCE promising for a range of engineering applications.

Macromolecules (Washington, DC, United States) published new progress about Click chemistry. 7575-23-7 belongs to class alcohols-buliding-blocks, name is Pentaerythritol tetra(3-mercaptopropionate), and the molecular formula is C17H28O8S4, Safety of Pentaerythritol tetra(3-mercaptopropionate).

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Tian, Guangming published the artcilePhotodirected 2D-to-3D morphing structures of shape memory polycaprolactone/W18O49 nanowires composite film, Application of Pentaerythritol tetra(3-mercaptopropionate), the main research area is tungsten oxide polycaprolactone composite film photodirected shape memory effect.

Shape memory materials possess programmable complex and large deformations toward external stimuli, which are particularly essential for their potential applications. For the transformation of planar two-dimensional (2D) structures into complex 3D structures, the design of asym. or bilayer thin sheets is usually required. In this paper, we propose a facile strategy to achieve these complex 3D structures that can be transformed to various pre-determined shapes sequentially by laser-triggered site-specific deformations. The response of shape memory polycaprolactone (PCL) to laser is realized by phys. doping W18O49 nanowires into the cross-linked PCL diacrylate matrix. When irradiated by 98 mW cm-2 laser, the pre-stretched PCL/W18O49 film shows an out-of-plane bending deformation due to the temperature gradient and single-domain orientation on the thickness between the upper layer and lower layer. The bending rates and amplitudes of the film can be tailored by adjusting the parameters of irradiation time, the film thickness as well as the pre-stretch strain. Remarkably, the pre-stretched film can automatically bend in more intricate complex deformations by integration with kirigami cuts in planar. Finally, we demonstrate that by activating the dynamic transesterification reaction within the same film, it can also achieve the 2D-to-3D transformations. With these decent features, this kind of novel PCL//W18O49 film shows great potential in the field of biomedical devices or soft robotics.

Science China Materials published new progress about Click chemistry. 7575-23-7 belongs to class alcohols-buliding-blocks, name is Pentaerythritol tetra(3-mercaptopropionate), and the molecular formula is C17H28O8S4, Application of Pentaerythritol tetra(3-mercaptopropionate).

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Sudhakar, Sekar published the artcileBiodistribution and pharmacokinetics of thiolated chitosan nanoparticles for oral delivery of insulin in vivo, Application In Synthesis of 7575-23-7, the main research area is thiolated chitosan nanoparticle insulin oral delivery pharmacokinetics; Bioavailability; Chitosan; Insulin; Mucoadhesion; Oral delivery.

To improve the quality of life of diabetic patients, oral delivery of insulin would be better than s.c. injection, and the encapsulation of insulin for its oral delivery is a promising alternative one. In this study, we prepared an oral insulin delivery system using thiolated chitosan nanoparticles (TCNPs) loaded with insulin (Ins) and tested under in vitro and in vivo systems. TCNPs prepared from CS and pentaerythritol tetrakis (3-mercaptopropionate) (PETMP) at 4:1 ratio showed 220 ± 4 nm, 2.3 ± 1 mV, and 119 ± 4μmol g-1 in their size, charge and sulfhydryl content, resp . There was a sustained release of insulin from the TCNPs at pH 5.3. TCNPs treatment did not alter cell viability in vitro and oral administration of TCNPs reached over the tip of the microvilli near the intestinal mucosa in vivo. There were increased and decreased the levels of insulin and glucose in the blood, resp. when Ins-TCNPs were orally administered in the diabetes induced rats. Thus, our results suggested that the insulin stays significantly for a prolonged period to make bio-distribution and bioavailability due to its interaction with the mucus of the intestine, thus offering a better oral insulin delivery system for diabetic patients.

International Journal of Biological Macromolecules published new progress about Bioavailability. 7575-23-7 belongs to class alcohols-buliding-blocks, name is Pentaerythritol tetra(3-mercaptopropionate), and the molecular formula is C17H28O8S4, Application In Synthesis of 7575-23-7.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts