Tag: M.W=250-300

Hu, Guodong; Zhong, Miao; Zhao, Jintao; Gao, Hao; Gan, Lu; Zhang, Hong; Zhang, Shengxiang; Fang, Jianguo published the artcile< Fluorescent Probes for Imaging Protein Disulfides in Live Organisms>, Product Details of C19H16O, the main research area is fluorescent probe imaging protein disulfide in vivo; environment-sensitive probes; fluorescent probes; in vivo imaging; mouse stroke model; protein disulfides; two-photon.

Cellular redox homeostasis is predominantly controlled by the ratio of thiols and disulfides, and reversible thiol-disulfide exchange reactions are fundamental of the biol. redox regulation. However, due to the dynamic exchanges of thiols and disulfides, the detection, especially the in situ detection, of protein disulfides (PDS) is challenging. We employ the strategy, i.e., the increase of emission upon an environment-sensitive dye binding to proteins, to design PDS probes and discover a two-photon probe PDSTP590 (S6) (I) that selectively recognizes PDS in live organisms. With the aid of the probe, we further disclose the elevation of PDS in brains of the mouse stroke model.

ACS Sensors published new progress about Bovine serum albumin Role: ANT (Analyte), BSU (Biological Study, Unclassified), ANST (Analytical Study), BIOL (Biological Study). 76-84-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C19H16O, Product Details of C19H16O.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Cummins, Daniel C.; Alvarado, Jessica G.; Zaragoza, Jan Paulo T.; Effendy Mubarak, Muhammad Qadri; Lin, Yen-Ting; de Visser, Sam P.; Goldberg, David P. published the artcile< Hydroxyl Transfer to Carbon Radicals by Mn(OH) vs Fe(OH) Corrole Complexes>, Safety of Triphenylmethanol, the main research area is manganese iron corrole complex hydroxyl transfer tertiary carbon radical.

The transfer of •OH from metal-hydroxo species to carbon radicals (R•) to give hydroxylated products (ROH) is a fundamental process in metal-mediated heme and nonheme C-H bond oxidations This step, often referred to as the hydroxyl “”rebound”” step, is typically very fast, making direct study of this process challenging if not impossible. In this report, we describe the reactions of the synthetic models M(OH)(ttppc) (M = Fe (1), Mn (3); ttppc = 5,10,15-tris(2,4,6-triphenyl)phenyl corrolato3-) with a series of triphenylmethyl carbon radical (R•) derivatives ((4-X-C6H4)3C•; X = OMe, tBu, Ph, Cl, CN) to give the one-electron reduced MIII(ttppc) complexes and ROH products. Rate constants for 3 for the different radicals ranged from 11.4(1) to 58.4(2) M-1 s-1, as compared to those for 1, which fall between 0.74(2) and 357(4) M-1 s-1. Linear correlations for Hammett and Marcus plots for both Mn and Fe were observed, and the small magnitudes of the slopes for both correlations imply a concerted •OH transfer reaction for both metals. Eyring analyses of reactions for 1 and 3 with (4-X-C6H4)3C• (X = tBu, CN) also give good linear correlations, and a comparison of the resulting activation parameters highlight the importance of entropy in these •OH transfer reactions. D. functional theory calculations of the reaction profiles show a concerted process with one transition state for all radicals investigated and help to explain the electronic features of the OH rebound process. Hydroxyl transfer is a critical step catalyzed by metallo-oxygenases. Rates of hydroxyl transfer for FeOH and MnOH heme analogs with tertiary carbon radical derivatives show that FeOH reactivity is more sensitive to the electronic structure of the substrate. Variable temperature kinetic anal. and DFT calculations indicate a highly ordered transition state and a significant role for entropy in the activation barriers.

Inorganic Chemistry published new progress about Activation enthalpy. 76-84-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C19H16O, Safety of Triphenylmethanol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Li, Xiaorui; Chai, Liyuan; Ren, Junyu; Jin, Linfeng; Wang, Haiying; Li, Yiming; Ma, Shengqian published the artcile< Efficient collection of perrhenate anions from water using poly(pyridinium salts) via pyrylium mediated transformation>, SDS of cas: 76-84-6, the main research area is perrhenate anion collection water poly pyridinium salt pyrylium transformation.

Poly(pyridinium salts) (PPSs) with pos. charges on the backbones were designed and synthesized from the transformation of bispyrylium salts. Such materials exhibited good uptake capacity for rhenium capture from water, and excellent selectivity of ReO4- from competing anions. Furthermore, the advantages of facile synthesis and large-scale preparation make this material promising for practical use in industry.

Polymer Chemistry published new progress about Cationic polyelectrolytes. 76-84-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C19H16O, SDS of cas: 76-84-6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Margarita, Cristiana; Villo, Piret; Tunon, Hernando; Dalla-Santa, Oscar; Camaj, David; Carlsson, Robin; Lill, Malin; Ramstroem, Anja; Lundberg, Helena published the artcile< Zirconium-catalysed direct substitution of alcohols: enhancing the selectivity by kinetic analysis>, Category: alcohols-buliding-blocks, the main research area is ether preparation; alc substitution zirconium catalyst; thioether preparation; thiol alc substitution zirconium catalyst.

Kinetic anal. was used as a tool for rational optimization of a catalytic, direct substitution of alcs. to enable the selective formation of unsym. ethers, thioethers, and Friedel-Crafts alkylation products using a moisture-tolerant and com. available zirconium complex (2 to 8 mol%). Operating in air and in the absence of dehydration techniques, the protocol furnished a variety of products in high yields, including glycosylated alcs. and sterically hindered ethers. In addition, the kinetic studies provided mechanistic insight into the network of parallel transformations that take place in the reaction, and helped to elucidate the nature of the operating catalyst.

Catalysis Science & Technology published new progress about Alcohols Role: RCT (Reactant), RACT (Reactant or Reagent). 76-84-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C19H16O, Category: alcohols-buliding-blocks.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Elorriaga, David; de la Cruz-Martinez, Felipe; Rodriguez-Alvarez, Maria Jesus; Lara-Sanchez, Agustin; Castro-Osma, Jose Antonio; Garcia-Alvarez, Joaquin published the artcile< Fast Addition of s-Block Organometallic Reagents to CO2-Derived Cyclic Carbonates at Room Temperature, Under Air, and in 2-Methyltetrahydrofuran>, Computed Properties of 76-84-6, the main research area is tertiary alc hydroxy ester ketone preparation green solvent methyltetrahydrofuran; organomagnesium lithium reagents cyclic carbonate addition ring opening; CO2; Grignard reagents; cyclic carbonates; green chemistry; organolithium compounds.

Fast addition of highly polar organometallic reagents (RMgX/RLi) to cyclic carbonates (derived from CO2 as a sustainable C1 synthon) has been studied in 2-methyltetrahydrofuran as a green reaction medium or in the absence of external volatile organic solvents, at room temperature, and in the presence of air/moisture. These reaction conditions are generally forbidden with these highly reactive main-group organometallic compounds The correct stoichiometry and nature of the polar organometallic alkylating or arylating reagent allows straightforward synthesis of highly substituted tertiary alcs., β-hydroxy esters, or sym. ketones, working always under air and at room temperature Finally, an unprecedented one-pot/two-step hybrid protocol is developed through combination of an Al-catalyzed cycloaddition of CO2 and propylene oxide with the concomitant fast addition of RLi reagents to the in situ and transiently formed cyclic carbonate, thus allowing indirect conversion of CO2 into the desired highly substituted tertiary alcs. without need for isolation or purification of any reaction intermediates.

ChemSusChem published new progress about Addition reaction. 76-84-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C19H16O, Computed Properties of 76-84-6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Mehdipour, Ebrahim; Baharlouei, Ehsan; Zarnegar, Zohre published the artcile< Selective trimethylsilylation of alcohols and phenols with hexamethyldisilazane catalyzed by LaCoO3 perovskite>, Recommanded Product: Triphenylmethanol, the main research area is green trimethylsilylation alc phenol hexamethyldisilazane cobalt lanthanum perovskite catalyst.

Trimethylsilylation of alcs. and phenols were carried out under solvent-free conditions with hexamethyldisilazane (HMDS) using LaCoO3 perovskite. LaCoO3 as an efficient catalyst accelerated this reaction under milder condition. The advantages of this method are evident regarding, easy separation, low cost and low catalyst loading, lack of pollution, easy work-up, and selective protection of primary and secondary alcs.

Iranian Chemical Communication published new progress about Alcohols Role: RCT (Reactant), RACT (Reactant or Reagent). 76-84-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C19H16O, Recommanded Product: Triphenylmethanol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Chan, Jessica Z.; Yesilcimen, Ahmet; Cao, Min; Zhang, Yuyang; Zhang, Bochao; Wasa, Masayuki published the artcile< Direct Conversion of N-Alkylamines to N-Propargylamines through C-H Activation Promoted by Lewis Acid/Organocopper Catalysis: Application to Late-Stage Functionalization of Bioactive Molecules>, SDS of cas: 76-84-6, the main research area is diastereoselective enantioselective synthesis propargylamine; alkylamine conversion propargylamine Lewis acid copper catalysis; carbon hydrogen bond activation alkylamine conversion propargylamine.

An efficient catalytic method to convert an α-C-H bond of N-alkylamines into an α-C-alkynyl bond was developed. In the past, such transformations were carried out under oxidative conditions, and the enantioselective variants were confined to tetrahydroisoquinoline derivatives Here, we disclose a method for the union of N-alkylamines and trimethylsilyl alkynes, without the presence of an external oxidant and promoted through cooperative actions of two Lewis acids, B(C6F5)3 and a Cu-based complex. A variety of propargylamines can be synthesized in high diastereo- and enantioselectivity. The utility of the approach is demonstrated by the late-stage site-selective modification of bioactive amines. Kinetic investigations that shed light on various mechanistic nuances of the catalytic process are presented.

Journal of the American Chemical Society published new progress about Alkynes Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation) (trimethylsilyl). 76-84-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C19H16O, SDS of cas: 76-84-6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts