Tag: M.W=250-300

Pang, Yue-Hong published the artcileCovalent organic framework modified carbon cloth for ratiometric electrochemical sensing of bisphenol A and S, HPLC of Formula: 80-09-1, the publication is Microchimica Acta (2022), 189(5), 189, database is CAplus and MEDLINE.

A novel ratiometric electrochem. sensor was developed based on a carbon cloth electrodeposited with silver nanoparticles and drop-coated by covalent organic framework (COF-LZU1) for simultaneous determination of bisphenol A (BPA) and bisphenol S (BPS). Carbon cloth exhibited a significantly larger electrochem. active area than common glassy carbon electrodes (27.5 times). Silver nanoparticles not only provided a stable reference signal but also enhanced electroactivity for the oxidation of BPA and BPS. COF-LZU1 with good adsorption performance and large periodic π-arrays promoted the enrichment of BPA and BPS to further increase the current response. Compared with the traditional single-signal electrochem. sensor, the developed ratiometric sensor exhibited better reproducibility and a wider linear range for BPA and BPS from 0.5 to 100μM with a limit of detection of 0.15μM. Furthermore, the developed sensor showed excellent stability and superior anti-interference ability. The real sample anal. for BPA and BPS has been successfully carried out in mineral water, electrolyte drink, tea, juice, and beer with recoveries of 88.3-111.7%. The developed ratiometric sensor is expected to be a candidate for the preparation of other electrochem. sensors and the anal. of addnl. practical samples.

Microchimica Acta published new progress about 80-09-1. 80-09-1 belongs to alcohols-buliding-blocks, auxiliary class Ploymers, name is 4,4′-Sulfonyldiphenol, and the molecular formula is C12H10O4S, HPLC of Formula: 80-09-1.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Aimuzi, Ruxianguli published the artcileExposure to phthalates, phenols, and parabens mixture and alterations in sex steroid hormones among adolescents, Recommanded Product: 4,4′-Sulfonyldiphenol, the publication is Chemosphere (2022), 134834, database is CAplus and MEDLINE.

Exposure to phthalates (PAEs), phenols, and parabens has been linked with sex hormone imbalance; however, previous studies were predominantly limited to adults and failed to examine the combined effects of these chems. mixture among adolescents. Thus, we used the data from the National Health and Nutrition Examination Survey (2013-2016) to explore the associations of urinary PAEs, phenols, and parabens biomarkers with sex hormones among participants aged 12-19 years old (n = 613). Latent class anal. (LCA) and quantile-based g-computation (QGC) were applied to assess the associations of the latent exposure profiles and chems. mixture with sex hormone indicators, including steroid hormones and sex hormone binding globulin (SHBG), in adolescents and by sex. Using LCA, four latent classes were identified among all participants. Compared with the class characterized by “Low exposure”, the class represented by “High PAEs” [mono (2-ethyl-5-carboxypentyl) phthalate (MECPP), mono (2-ethyl-5-hydroxyhexyl) phthalate (MEHHP), and monobenzyl phthalate (MBZP)] had lower level of estradiol (E2) [β = -0.249, 95% confidence interval (CI): -0.419, -0.08], free androgen index (FAI) (β = -0.258, 95%CI: -0.512, -0.005) and free testosterone (FT) (β = -0.248, 95%CI: -0.496, -0.001) among male adolescents. These results were echoed by the results in QGC analyses, where PAEs mixture was neg. associated with E2 (β = -0.137, 95% CI: -0.263, -0.011), FAI (β = -0.198, 95%CI: -0.387, -0.008) and FT (β = -0.189, 95%CI: -0.375, -0.002) among male adolescents. By contrast, the associations of the identified latent classes or chems. mixture with sex hormone indicators were generally nonsignificant among female counterparts, except for a pos. association between PAEs mixture and SHBG (β = 0.121, 95%CI: 0.012, 0.23). Our study demonstrated that exposure to PAEs, particularly MECPP, MEHHP, and MBZP, would be a threat to the sex hormone homeostasis of male adolescents.

Chemosphere published new progress about 80-09-1. 80-09-1 belongs to alcohols-buliding-blocks, auxiliary class Ploymers, name is 4,4′-Sulfonyldiphenol, and the molecular formula is C12H10O4S, Recommanded Product: 4,4′-Sulfonyldiphenol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Ao, Junjie published the artcilePatterns of environmental exposure to phenols in couples who plan to become pregnant, Category: alcohols-buliding-blocks, the publication is Science of the Total Environment (2022), 153520, database is CAplus and MEDLINE.

Phenols are widely used in consumer products and known for their reproductive toxicities. Little is known regarding the environmental exposure to phenols in couples prior to conception, a key period affecting fertility. We measured the urinary concentrations of six parabens and seven bisphenols in 903 pre-conception couples in China. We investigated the occurrence, distribution, source and health risk of phenols in husbands and wives sep., and the correlation and difference in phenol concentrations between couples. Similar distribution profiles of urinary phenols were observed between females and males. Me 4-hydroxybenzoate (MeP) and bisphenol A (BPA) were the predominant compounds The level of urinary phenols in our population was mostly lower than the global levels. Exposure to phenols was linked to processed food and personal care products. The correlations between phenols in males and females were moderate (0.218-0.686), while the correlation in phenols between husband and wife was low (0.009-0.215). Female had a significantly higher urinary phenol levels than male (P < 0.05). Urinary phenols in couples were associated with family income, type of drinking water and frequency of household cleaning. Household factors accounted for ≤1.5% of variance in phenol levels between couples, suggesting that individual variations may be the major factor. Risk assessment showed that exposure to phenols posed a low hazard to 17.5% of the couples in our population. Our findings provide important evidence of environmental exposure to phenols in couples of child-bearing age.

Science of the Total Environment published new progress about 80-09-1. 80-09-1 belongs to alcohols-buliding-blocks, auxiliary class Ploymers, name is 4,4′-Sulfonyldiphenol, and the molecular formula is C12H10O4S, Category: alcohols-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Ren, Xinyi published the artcileAsymmetric Alkoxy- and Hydroxy-Carbonylations of Functionalized Alkenes Assisted by β-Carbonyl Groups, Application In Synthesis of 20880-92-6, the publication is Angewandte Chemie, International Edition (2021), 60(32), 17693-17700, database is CAplus and MEDLINE.

As a fundamental type of carbonylation reaction, the alkoxy- and hydroxy-carbonylation of unsaturated hydrocarbons constitutes one of the most important industrial applications of homogeneous catalysis. However, owing to the difficulties in controlling multi-selectivities for asym. hydrocarbonylation of alkenes, this reaction is typically limited to vinylarenes and analogs. In this work, a highly efficient asym. alkoxy- and hydroxy-carbonylation of β-carbonyl functionalized alkenes was developed, providing practical and easy access to various densely functionalized chiral mols. with high optical purity from broadly available alkenes, CO, and nucleophiles (>90 examples, 84-99% ee). This protocol features mild reaction conditions and a broad substrate scope, and the products can be readily transformed into a diverse array of chiral heterocycles. Control experiments revealed the key role of the β-carbonyl group in determining the enantioselectivity and promoting the activity, which facilitates chiral induction by coordination to the transition metal as rationalized by DFT calculations The strategy of utilizing an innate functional group as the directing group on the alkene substrate might find further applications in catalytic asym. hydrocarbonylation reactions.

Angewandte Chemie, International Edition published new progress about 20880-92-6. 20880-92-6 belongs to alcohols-buliding-blocks, auxiliary class Other Aliphatic Heterocyclic,Chiral,Alcohol, name is ((3aS,5aR,8aR,8bS)-2,2,7,7-Tetramethyltetrahydro-3aH-bis([1,3]dioxolo)[4,5-b:4′,5′-d]pyran-3a-yl)methanol, and the molecular formula is C12H20O6, Application In Synthesis of 20880-92-6.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Lu, Xi published the artcileNickel-catalyzed allylic defluorinative alkylation of trifluoromethyl alkenes with reductive decarboxylation of redox-active esters, Application of ((3aS,5aR,8aR,8bS)-2,2,7,7-Tetramethyltetrahydro-3aH-bis([1,3]dioxolo)[4,5-b:4′,5′-d]pyran-3a-yl)methanol, the publication is Chemical Science (2019), 10(3), 809-814, database is CAplus and MEDLINE.

An efficient method was developed for the synthesis of functionalized gem-difluoroalkenes I [R = c-hexyl, 4-BrC₆H₄(CH₂)₂, 4-CNC₆H₄O(CH₂)₂C(Me)₂, etc.; Ar = 3,4-(OMe)₂C₆H₃, 4-PhC₆H₄, 2-naphthyl, etc.] via nickel-catalyzed defluorinative reductive cross-coupling of trifluoromethyl alkenes with redox-active esters. The present reaction involved C(sp³)-F bond cleavage and C(sp³)-C(sp³) bond formation under very mild reaction conditions, while tolerating many sensitive functional groups and requiring minimal substrate protection. Therefore, this method provided an efficient and convenient approach for late-stage modification of biol. interesting mols.

Chemical Science published new progress about 20880-92-6. 20880-92-6 belongs to alcohols-buliding-blocks, auxiliary class Other Aliphatic Heterocyclic,Chiral,Alcohol, name is ((3aS,5aR,8aR,8bS)-2,2,7,7-Tetramethyltetrahydro-3aH-bis([1,3]dioxolo)[4,5-b:4′,5′-d]pyran-3a-yl)methanol, and the molecular formula is C12H20O6, Application of ((3aS,5aR,8aR,8bS)-2,2,7,7-Tetramethyltetrahydro-3aH-bis([1,3]dioxolo)[4,5-b:4′,5′-d]pyran-3a-yl)methanol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Zhao, C. published the artcileRemoval of bisphenol S from drinking water by adsorption using activated carbon and the mechanisms involved, Quality Control of 80-09-1, the publication is International Journal of Environmental Science and Technology (2022), 19(6), 5289-5300, database is CAplus.

Bisphenol S, an alternative chem. to bisphenol A, has a neg. effect on living organisms and has frequently been detected in drinking water systems. A promising and cost-effective method for removing bisphenol S from tap water is adsorption by activated carbon. However, activated carbon significantly decreased the adsorption capacity of bisphenol S in tap water comparing with that in deionized water based on the exptl. results. Dissolved organic matter in tap water was likely responsible for it. The adsorption kinetics can be described by a pseudo-second-order model. The Langmuir isotherm model can well describe the process, suggesting monolayer adsorption. The maximum adsorption capacity was calculated as 83.19 mg g^-1. Higher temperature and pH were unfavorable to the process. Changes in entropy, enthalpy, and Gibbs free energy were calculated and implied a spontaneous and exothermic adsorption process. Fourier transform IR spectroscopic anal. found that hydroxyl and amino functional groups are the main groups involved. The research provides a substantial basis for understanding bisphenol S removal from drinking water by adsorption using activated carbon to limit direct exposure to bisphenol S in drinking water.

International Journal of Environmental Science and Technology published new progress about 80-09-1. 80-09-1 belongs to alcohols-buliding-blocks, auxiliary class Ploymers, name is 4,4′-Sulfonyldiphenol, and the molecular formula is C18H23OP, Quality Control of 80-09-1.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Liu, Jiang published the artcileLate-stage construction of stapled peptides through Fujiwara-Moritani reaction between tryptophan and olefins, Safety of ((3aS,5aR,8aR,8bS)-2,2,7,7-Tetramethyltetrahydro-3aH-bis([1,3]dioxolo)[4,5-b:4′,5′-d]pyran-3a-yl)methanol, the publication is Chemical Communications (Cambridge, United Kingdom) (2021), 57(88), 11661-11664, database is CAplus and MEDLINE.

Herein, the first example of a palladium-catalyzed Fujiwara-Moritani reaction for olefination of tryptophan (Trp) residues, free from directing groups, was presented. The developed reaction proceeds efficiently for peptide modification, ligation and peptide stapling.

Chemical Communications (Cambridge, United Kingdom) published new progress about 20880-92-6. 20880-92-6 belongs to alcohols-buliding-blocks, auxiliary class Other Aliphatic Heterocyclic,Chiral,Alcohol, name is ((3aS,5aR,8aR,8bS)-2,2,7,7-Tetramethyltetrahydro-3aH-bis([1,3]dioxolo)[4,5-b:4′,5′-d]pyran-3a-yl)methanol, and the molecular formula is C12H20O6, Safety of ((3aS,5aR,8aR,8bS)-2,2,7,7-Tetramethyltetrahydro-3aH-bis([1,3]dioxolo)[4,5-b:4′,5′-d]pyran-3a-yl)methanol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Xing, Wei-Long published the artcileEfficient Decarboxylative/Defluorinative Alkylation for the Synthesis of gem-Difluoroalkenes through an S_N2′ Type Route, Name: ((3aS,5aR,8aR,8bS)-2,2,7,7-Tetramethyltetrahydro-3aH-bis([1,3]dioxolo)[4,5-b:4′,5′-d]pyran-3a-yl)methanol, the publication is Chinese Journal of Chemistry (2022), 40(3), 323-328, database is CAplus.

An efficient decarboxylative/defluorinative alkylation for synthesizing gem-difluoroalkenes F₂C:CRCH₂CR¹R²R³ [R = 4-PhC₆H₄, naphthalen-2-yl, 1-methyl-1H-indol-5-yl, etc.; R¹ = H, Me, Et; R² = H, Me, Et, Ph, etc.; R¹R² = (CH₂)₃; R³ = Ph, CN, COOEt, etc.] is described, providing a general method for installation of the challenging alkyl fragments containing γ-electron-withdrawing groups into γ-trifluoromethyl alkenes RC(CF₃):CH₂. Mechanistic studies suggest that this process involves an S_N2′-type synthetic route in the absence of transition-metal catalysts or photocatalysis. Moreover, this protocol can easily be scaled up, and successfully applied to the modification of biol. active mols., thus complementing methodologies that give access to structurally versatile gem-difluoroalkenes.

Chinese Journal of Chemistry published new progress about 20880-92-6. 20880-92-6 belongs to alcohols-buliding-blocks, auxiliary class Other Aliphatic Heterocyclic,Chiral,Alcohol, name is ((3aS,5aR,8aR,8bS)-2,2,7,7-Tetramethyltetrahydro-3aH-bis([1,3]dioxolo)[4,5-b:4′,5′-d]pyran-3a-yl)methanol, and the molecular formula is C14H12O3, Name: ((3aS,5aR,8aR,8bS)-2,2,7,7-Tetramethyltetrahydro-3aH-bis([1,3]dioxolo)[4,5-b:4′,5′-d]pyran-3a-yl)methanol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Yang, Pan published the artcileExposure profiles and predictors of a cocktail of environmental chemicals in Chinese men of reproductive age, Formula: C12H10O4S, the publication is Chemosphere (2022), 134337, database is CAplus and MEDLINE.

Personal care products, such as additives, have raised widespread concerns about the potential threat to male reproductive health. The spermatogenesis in humans lasts for approx. 90 days, the average levels of these chems. remain unclear during spermatogenesis. In our study, we pooled urine samples from each man during the days of 1-15, 16-31, 32-63, and ≥64, and examined exposure to 48 typical additive chems. By principal component anal. (PCA), k-means clustering, and Spearman’s rank correlations, we then identified 6 PC scores and 4 clusters based on profiles of these chems. Some industrial, com. or structural similar chems. (e.g., phthalates) were significantly correlated compared to unrelated chems. (e.g., benzophenone). PCA scores were associated with individual lifestyles (e.g., household income, tea consumption, and drinking tap water). Distinct exposure components and exposure patterns of personal care products may help the reproductive health assessment of men. We suggested more concerns for widespread exposure to these chems. for men.

Chemosphere published new progress about 80-09-1. 80-09-1 belongs to alcohols-buliding-blocks, auxiliary class Ploymers, name is 4,4′-Sulfonyldiphenol, and the molecular formula is C8H10O2, Formula: C12H10O4S.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Goni, Miguel A. published the artcileThe diagenetic behavior of cutin acids in buried conifer needles and sediments from a coastal marine environment, Name: 17-Hydroxyheptadecanoic acid, the main research area is cutin acid diagenesis coastal sediment; diagenesis cutin acid forest litter; conifer needle cutin acid composition; fatty acid diagenesis needle sediment.

Whole green, litter, and sedimentary fir, hemlock, and cedar needles and bulk sediments collected from the Dabob Bay region in Washington State were analyzed for their cutin-derived CuO reaction products. All samples yielded dihydroxyhexadecanoic acid isomers (x,ω-C16), 16-hydroxyhexadecanoic acid (ω-C16), 14-hydroxytetradecanoic acid (ω-C14), and 18-hydroxyoctadec-9-enoic acid (ω-C18:1) as the major cutin acids. Fir/hemlock needle mixtures were characterized by a high abundance of the 9,16-dihydroxyhexadecanoic acid positional isomer, while cedar needles produced primarily the 10,16-dihydroxy counterpart. Cutin acids accounted for ∼3% of tissue C in green needles, ∼4% in needle litter, 0.5-1.5% in sedimentary needles, and ∼0.1% of the organic C (OC) in bulk sediments. Approx. 80% of the original cutin acids in fresh green needles were lost from the deepest (∼100 yr old) sedimentary tissues. Cutin was more active than lignin and polysaccharides, but more stable than the cyclitol components of the same needles. Comparative diagenetic losses of the individual cutin acids were not uniform and suggest that addnl. hydroxy groups and the presence of C double bonds both increase overall reactivity. The relative stability series derived for all the mol. constituents measured is: total vanillyl phenols > total p-hydroxy phenols, ferulic acid, most aldoses, bulk organic matter > mannose, ω-C14, ω-C16 ≥ ω-C18:1 > glucose, p-coumaric acid, x,ω-C16 > all cyclitols. Diagenetically induced changes in the various cutin parameters used to characterize nonwoody vascular plant tissues were not large enough to confuse degraded conifer tissues with other cutin sources. Based on these trends, the finely disseminated cutin-bearing tissues in Dabob Bay sediments appear to be comprised approx. of equal amounts of highly degraded fir/hemlock and cedar needle fragments. According to this estimate, nonwoody vascular plant debris accounted for ∼15% of the total organic matter present in these sediments.

Geochimica et Cosmochimica Acta published new progress about Bay sediments. 13099-34-8 belongs to class alcohols-buliding-blocks, name is 17-Hydroxyheptadecanoic acid, and the molecular formula is C17H34O3, Name: 17-Hydroxyheptadecanoic acid.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts