Tag: M.W=250-300

Liu, Hui; Zhou, Si-Yu; Wen, Guo-En; Liu, Xu-Xue; Liu, De-Yong; Zhang, Qing-Ju; Schmidt, Richard R.; Sun, Jian-Song published the artcile< The 2,2-Dimethyl-2-(ortho-nitrophenyl)acetyl (DMNPA) Group: A Novel Protecting Group in Carbohydrate Chemistry>, Product Details of C12H20O6, the main research area is dimethyl nitrophenyl acetyl protecting group carbohydrate chem.

The 2,2-dimethyl-2-(ortho-nitrophenyl)acetyl (DMNPA) group was introduced to synthetic carbohydrate chem. as a protecting group (PG) for the first time. Benefiting from a unique chem. structure and novel deprotection conditions, the DMNPA group can be cleaved rapidly and mutually orthogonal to other PGs. Orchestrated application of the DMNPA group with other PGs led to the highly efficient synthesis of the glycan of thornasterside A.

Organic Letters published new progress about Glycosides Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation) (protected). 4064-06-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C12H20O6, Product Details of C12H20O6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Akiyama, Ryo; Sugaya, Mariko; Shinozaki, Hiraku; Yamamoto, Tetsuya published the artcile< NHC-coordinated palladacycle catalyzed 1,2-addition of arylboronates to unactivated ketones>, Name: Triphenylmethanol, the main research area is carbene palladacycle catalyzed addition arylation arylboronate unactivated ketone; tertiary alc preparation; substituted gamma lactone preparation.

Pd catalyzed intermol. 1,2-addition of arylboronate to unactivated ketone was studied. NHC-coordinated palladacycle exhibited catalytic activity for the reactions and provided the corresponding tertiary alcs. and γ,γ-disubstituted γ-lactones in good to excellent yields.

Synthetic Communications published new progress about 1,2-Addition reaction. 76-84-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C19H16O, Name: Triphenylmethanol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Upadhyaya, Kapil; Bagul, Rahul S.; Crich, David published the artcile< Influence of Configuration at the 4- and 6-Positions on the Conformation and Anomeric Reactivity and Selectivity of 7-Deoxyheptopyranosyl Donors: Discovery of a Highly Equatorially Selective L-glycero-D-gluco-Heptopyranosyl Donor>, Formula: C12H20O6, the main research area is structure property stereoselective glycosylation glycoside disaccharide preparation; nucleophilic substitution hydrogen bonding glycosyl triflate neuraminic ulosonic acid; stereoselective glycosylation glycoside preparation configuration conformation deoxyheptopyranosyl disaccharide NMR.

The preparation of four per-O-benzyl-D- or L-glycero-D-galacto and D- or L-glycero-D-gluco heptopyranosyl sulfoxides and the influence of their side-chain conformations on reactivity and stereoselectivity in glycosylation reactions are described. The side-chain conformation in these donors is determined by the relative configuration of its point of attachment to the pyranoside ring and the two flanking centers in agreement with a recent model. In the D- and L-glycero-D-galacto glycosyl donors, the D-glycero-D-galacto isomer with the more electron-withdrawing trans,gauche conformation of its side chain was the more equatorially selective isomer. In the D- and L-glycero-D-gluco glycosyl donors, the L-glycero-D-gluco isomer with the least disarming gauche-gauche side-chain conformation was the most equatorially selective donor. Variable temperature NMR studies, while supporting the formation of intermediate glycosyl triflates at -80°C in all cases, were inconclusive owing to a change in the decomposition mechanism with the change in configuration. It is suggested that the equatorial selectivity of the L-glycero-D-gluco isomer arises from H-bonding between the glycosyl acceptor and O6 of the donor, which is poised to deliver the acceptor anti-periplanar to the glycosyl triflate, resulting in a high degree of SN2 character in the displacement reaction.

Journal of Organic Chemistry published new progress about Conformation. 4064-06-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C12H20O6, Formula: C12H20O6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Lee, Juyeol; Kang, Soyeong; Kim, Jungjoon; Moon, Dohyun; Rhee, Young Ho published the artcile< A Convergent Synthetic Strategy towards Oligosaccharides containing 2,3,6-Trideoxypyranoglycosides>, Formula: C12H20O6, the main research area is palladium catalyst ring closure metathesis oligosaccharide preparation crystal structure; oligosaccharide deoxypyranoglycoside preparation stereoselective hydroalkoxylation alkoxyallene; asymmetric synthesis; carbohydrates; diastereoselectivity; oligosaccharides; palladium.

A de novo synthetic strategy for the production of oligosaccharides containing 2,3,6-trideoxypyranoglycoside is reported. The key event is the Pd-catalyzed asym. diastereoselective hydroalkoxylation of ene-alkoxyallene-linked glycosidic fragments. The utility of this approach was demonstrated by the activation-free, stereo-divergent, and convergent synthesis of various 2-deoxyoligosaccharides, as well as their aglycon conjugates.

Angewandte Chemie, International Edition published new progress about Cross-metathesis. 4064-06-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C12H20O6, Formula: C12H20O6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Jin, Pengkang; Ren, Bo; Wang, Xiaochang C.; Jin, Xin; Shi, Xuan published the artcile< Mechanism of microbial metabolic responses and ecological system conversion under different nitrogen conditions in sewers>, Synthetic Route of 76-84-6, the main research area is microbial metabolic responses ecol system nitrogen condition sewer; Ecological system; Functional bioconversion; Metabolization response; Nitrogen source; Urban sewer system.

However, the mechanisms underlying the involvement of nitrogen-associated pollutants in sewer ecosystems remain unknown. In this study, the effects of two typical nitrogen ratios (organic/inorganic nitrogen: 7/3 (Group A) and 3/7 (Group B)) on carbon, nitrogen, and sulfur bioconversions were investigated in a pilot sewer. The distribution of amino acids, such as proline, glycine and methionine, was significantly different between Groups A and B, and carbon-associated communities (based on 16S rRNA gene copies) were more prevalent in Group A, while sulfur and nitrogen-associated communities were more prevalent in Group B. To explore the effect of nitrogen on microbial response mechanisms, metagenomics-based methods were used to investigate the roles of amino acids involved in carbon, nitrogen, and sulfur bioconversion in sewers. Proline, glycine, and tyrosine in Group A promoted the expression of genes associated with cell membrane transport and increased the rate of protein synthesis, which stimulated the enrichment of carbon-associated communities. The transmembrane transport of higher concentrations of alanine and methionine in Group B was essential for cell metabolism and nutrient transport, thereby enriching nitrogen and sulfur-associated communities. In this investigation, insights into carbon, nitrogen and sulfur bioconversions in sewer ecosystems were revealed, significantly improving the understanding of the sewer ecosystem within a community context.

Water Research published new progress about Acidithiobacillus. 76-84-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C19H16O, Synthetic Route of 76-84-6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Liu, Lei; Zhou, Feng; Hu, Jun; Cheng, Xiaoxiao; Zhang, Wei; Zhang, Zhengbiao; Chen, Gaojian; Zhou, Nianchen; Zhu, Xiulin published the artcile< Topological glycopolymers as agglutinator and inhibitor: Cyclic versus linear>, SDS of cas: 4064-06-6, the main research area is glycopolymer galactose modified cyclic linear inhibition amyloid aggregation; agglutinators; cyclic polymers; glycopolymers; inhibition; topological difference.

Carbohydrates play an important role in biol. processes for their specific interactions with proteins. Cyclic glycopolymers are promising to mimic the topol. of natural macrocycle-biomacromols. due to their unique architecture of lacking chain ends. To systematically study the effect of glycopolymer architecture on the interactions with protein, the cyclic glycopolymers bearing galactose side-chain (cyclic PMAGn) with three ds.p. (n = 14, 24, 47) are prepared for the first time. The cyclic PMAGn exhibits unique properties in agglutinating and inhibiting proteins in subsequent studies by comparison with the linear precursor with the same mol. weights More impressively, the cyclic PMAGn highlight the improved performance of cyclic architecture. For example, the cyclic PMAGn shows superior inhibition abilities to suppress amyloid formation from amyloid β protein fragment 1-42 aggregation and block the specific interaction between bacteria and galactose-modified surface compared to that of resp. linear counterpart. This interesting finding suggests that the architecture of cyclic glycopolymers may be capable of optimizing the ability to bind or inhibit proteins in biol. processes.

Macromolecular Rapid Communications published new progress about Agglutination. 4064-06-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C12H20O6, SDS of cas: 4064-06-6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Li, Shun-Shun; Zhu, Nengbo; Jing, Ya-Nan; Li, Yajun; Bao, Hongli; Wan, Wen-Ming published the artcile< Barbier Self-Condensing Ketyl Polymerization-Induced Emission: A Polarity Reversal Approach to Reversed Polymerizability>, Recommanded Product: Triphenylmethanol, the main research area is hydroxybenzophenone condensing ketyl radical anion polymerization photophys property; Optical Property; Organic Chemistry; Polymers.

Carbon-carbon bond formation through polarity reversal ketyl radical anion coupling of carbonyls has inspired new reaction modes to this cornerstone carbonyl group and played significant roles in organic chem. The introduction of this resplendent polarity reversal ketyl strategy into polymer chem. will inspire new polymerization mode with unpredicted discoveries. Here we show the successful introduction of polarity reversal ketyl approach to polymer chem. to realize self-condensing ketyl polymerization with polymerization-induced emission. In this polarity reversal approach, it exhibits intriguing reversed polymerizability, where traditional excellent leaving groups are not suitable for polymerization but challenging polymerizations involving the cleavage of challenging C-F and C-CF3 bonds are realized under mild Barbier conditions. This polarity reversal approach enables the polymer chem. with polarity reversal ketyl mode, opens up a new avenue toward the polymerization of challenging C-X bonds under mild conditions, and sparks design inspiration of new reaction, polymerization, and functional polymer.

iScience published new progress about Barbier reaction. 76-84-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C19H16O, Recommanded Product: Triphenylmethanol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Molla, Mosidur Rahaman; Das, Pradip; Guleria, Kanika; Subramanian, Ranga; Kumar, Amit; Thakur, Rima published the artcile< Cyanomethyl Ether as an Orthogonal Participating Group for Stereoselective Synthesis of 1,2-trans-β-O-Glycosides>, Application In Synthesis of 4064-06-6, the main research area is tetrazole glycoside cyclization azide cyanide glycoside preparation; disaccharide stereoselective glycosylation thioglycoside glycoside preparation protecting group cyanomethyl.

Stereoselective formation of glycosidic linkages has been the prime focus for contemporary carbohydrate chem. Herein, we report cyanomethyl (CNMe) ether as an efficient and effective participating orthogonal protecting group for the stereoselective synthesis of 1,2-trans-β-O-glycosides. The participating group facilitated good to high β-selective glycosylation with a broad range of electron-rich and electron-deficient glycosyl acceptors. Detailed exptl. and theor. studies reveal the involvement of CNMe ether in the formation of a six-membered imine-type cyclic intermediate for the observed stereoselectivity. Rapid incorporation and selective removal of the CNMe ether group in the presence of benzyl ether and isopropylidene acetal protection have also been reported here. The nitrile group provided an opportunity for the glyco-diversification through further derivatization.

Journal of Organic Chemistry published new progress about Cyclization. 4064-06-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C12H20O6, Application In Synthesis of 4064-06-6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Sheng, Yu-Jing; Su, Min; Xiao, Hang; Shi, Quan-Xi; Sun, Xiao-Li; Zhang, Ruliang; Bao, Hongli; Wan, Wen-Ming published the artcile< Barbier Hyperbranching Polymerization-Induced Emission from an AB-Type Monomer>, Application of C19H16O, the main research area is Barbier hyperbranching polymerization induced emission photophys property; barbier reaction; hyperbranching polymerization; luminescence; nonconjugated polymer; polymerization-induced emission.

Luminescent polymer materials have gained considerable research efforts in the past decades and are generally mol. designed by extending the π system of the polymer main chain or by incorporating chromophores into the polymer chain, which suffer from poor solubility, difficult synthesis, or multi-step procedures. Meanwhile, according to the step-growth polymerization theory, synthesis of hyperbranched polymers from an AB-type monomer is still challenging. Herein, we report a one-pot synthesis of nonconjugated luminescent hyperbranched polymer material via Barbier hyperbranching polymerization-induced emission (PIE) from an AB-type monomer. The key step in the realization of the hyperbranched polymer is bi-functionalization of a mono-functional group. Through a Barbier reaction between an organohalide and an ester group in one pot, bi-functionalization of mono-functional ester is realized through two-step nucleophilic additions, resulting in hyperbranched polytriphenylmethanols (HPTPM). Attributed to through-space conjugation and inter- and intramol. charge-transfer effects induced by polymer chain, nonconjugated HPTPMs are PIEgens, which are tunable by monomer structure and polymerization time. When all Ph groups are rotatable, HPTPM is aggregation-induced emission type PIEgen. Whereas, it is aggregation-caused quenching type PIEgen if some Ph groups are rotation forbidden. Further potential applications of PIEgen are in the fields of explosive detection and artificial light harvesting systems. This work, therefore, expands the monomer library and mol. design library of hyperbranched polymers through “”bi-functionalization of mono-functional group”” strategy, which eventually expands the preparation library of nonconjugated luminescent polymer materials through one-pot PIE from nonemissive monomer.

Chemistry – A European Journal published new progress about Aggregation-induced emission. 76-84-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C19H16O, Application of C19H16O.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Rodriguez Tzompantzi, Tomasa; Amaro Hernandez, Aldo Guillermo; Meza-Leon, Rosa Luisa; Bernes, Sylvain published the artcile< Deciphering the hydrogen-bonding scheme in the crystal structure of triphenylmethanol: a tribute to George Ferguson and co-workers>, Quality Control of 76-84-6, the main research area is triphenylmethanol crystal structure hydrogen bond; alcohol; crystal structure; disorder; hydrogen bond; topological chirality; triphenylmethanol.

The crystal structure of triphenylmethanol, C19H16O, has been redetermined using data collected at 295 and 153 K, and is compared to the model published by Ferguson et al. over 25 years ago [Ferguson et al. (1992). Acta Crystalline C48, 1272-1275] and that published by Serrano-Gonzalez et al., using neutron and X-ray diffraction data [Serrano-Gonzalez et al. (1999). J. Phys. Chem. B, 103, 6215-6223]. As predicted by these authors, the hydroxy groups are involved in weak intermol. hydrogen bonds in the crystal, forming tetrahedral tetramers based on the two independent mols. in the asym. unit, one of which is placed on the threefold symmetry axis of the R [inline formula omitted] space group. However, the reliable determination of the hydroxy H-atom positions is difficult to achieve, for two reasons. Firstly, a positional disorder affects the full asym. unit, which is split over two sets of positions, with occupancy factors of ca 0.74 and 0.26. Secondly, all hydroxy H atoms are further disordered, either by symmetry, or through a positional disorder in the case of parts placed in general positions. We show that the correct description of the hydrogen-bonding scheme is possible only if diffraction data are collected at low temperature The prochiral character of the hydrogen-bonded tetrameric supramol. clusters leads to enantiomorphic three-dimensional graphs in each tetramer. The crystal is thus a racemic mixture of supS and supR motifs, consistent with the centrosym. nature of the R [inline formula omitted] space group.

Acta Crystallographica, Section C: Structural Chemistry published new progress about Crystal structure. 76-84-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C19H16O, Quality Control of 76-84-6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts