Tag: M.W=250-300

Koruyucu, Meryem; Saltan, Fehmi; Kok, Gokhan; Akat, Hakan; Salman, Yesim published the artcile< Novel sugar based acrylate: synthesis, characterization and polymerization>, HPLC of Formula: 4064-06-6, the main research area is novel sugar based acrylate synthesis polymerization.

The present study has demonstrated that novel acrylic glycopolymers are successfully prepared by using monosaccharides containing an acrylate group (9-12). For this purpose, sugar based acrylate monomers were synthesized via ring opening method (Method B) and homopolymerization of this sugar oxypropylacrylates was performed using free radical polymerization The characterization of all the monomers and polymers were verified by 1HNMR, 13CNMR, FTIR and GPC techniques. The Glass transition temperatures and thermal characteristics of the polymers were also analyzed by using DSC and TG techniques. The thermal stability of prepared polymers have changed with the stereochem. of the carbohydrate moiety. Also, the mol. weight of the polymers has affected the thermal stability.

Journal of Polymer Materials published new progress about Glass transition temperature. 4064-06-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C12H20O6, HPLC of Formula: 4064-06-6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Zhang, Zhenguo; Liu, Xiaoxiao; Ji, Liang; Zhang, Ting; Jia, Zhenhua; Loh, Teck-Peng published the artcile< Metal-Free Access to (Spirocyclic)Tetrahydro-β-carbolines in Water Using an Ion-Pair as a Superacidic Precatalyst>, Reference of 76-84-6, the main research area is tetrahydro carboline preparation; aryl aldehyde tryptamine Pictet Spengler triarylcarbonium ion pair catalyst; spirocyclic tetrahydro carboline preparation; cyclic ketone tryptamine Pictet Spengler triarylcarbonium ion pair catalyst.

The unprecedented triarylcarbonium ion-pair-catalyzed Pictet-Spengler reaction of tryptamines with aromatic aldehydes and cyclic ketones in water was disclosed. Under metal-free conditions, diverse tetrahydro-β-carbolines/spirocyclic tetrahydro-β-carbolines I [R1 = H, Me, Cl, etc.; R2 = H; R3 = Ph, 4-MeC6H4, 2-naphthyl, etc.; R2R3 = (CH2)5, CH2CH2CH(Me)CH2CH2, CH2CH2N(Boc)CH2CH2, etc.] were obtained in good yields with excellent functional group tolerance, including late-stage modification of natural products and small mol. drugs. The practicability of this protocol was also characterized in the gram-scale synthesis of komavine and several other functional compounds Preliminary mechanistic studies indicated that in aqueous media the in situ-generated superacidic species from the carbonium ion pair with water was crucial to promote the Pictet-Spengler reaction.

ACS Catalysis published new progress about Aryl aldehydes Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 76-84-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C19H16O, Reference of 76-84-6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Schuh, Lukas; Mueller, Philipp; Torvisco, Ana; Stueger, Harald; Wrodnigg, Tanja M.; Haas, Michael published the artcile< Synthesis of D-Galactose-Substituted Acylsilanes and Acylgermanes. Model Compounds for Visible Light Photoinitiators with Intriguing High Solubility>, SDS of cas: 4064-06-6, the main research area is photocatalyst acylgermane acylsilane synthesis galactose glycoside preparation; acylgermane acylsilane synthesis galactose crystal structure photoinitiator crystal structure.

A convenient synthetic method to obtain D-galactose-substituted acylsilanes and acylgermanes is described. These acyl group 14 compounds are easily accessible in good yields. Their structural properties were analyzed by a combination of NMR, single crystal X-ray crystallog., and UV/vis spectroscopy. A D-galactose-substituted tetra-acylgermane represents a new interesting visible light photoinitiator based on its absorption properties as well as its high solubility

Organometallics published new progress about Crystal structure. 4064-06-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C12H20O6, SDS of cas: 4064-06-6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Sai, Masahiro published the artcile< Direct Synthesis of Indanes via Iron-Catalyzed Dehydrative Coupling/Friedel-Crafts Cyclization of Two Different Alcohols>, Safety of Triphenylmethanol, the main research area is iron catalyzed cascade dehydrative coupling Friedel Crafts alc; indane synthesis atom economic green.

We report herein a novel iron-catalyzed cascade dehydrative coupling/Friedel-Crafts cyclization of two different alcs., providing a variety of indanes, which are ubiquitous substructures found in natural products, pharmaceuticals, and functional materials. Importantly, the developed approach is highly atom-economic and environmentally benign, as it employs readily available alcs. as substrates and generates water as the only byproduct. Thus, e.g., benzhydrol + t-BuOH → 1,1-dimethyl-3-phenylindan (82%) employing Fe(OTf)3 and PhCF3 as solvent at 105°.

European Journal of Organic Chemistry published new progress about Alcohols Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 76-84-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C19H16O, Safety of Triphenylmethanol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Yang, Dong; von Krbek, Larissa K. S.; Yu, Le; Ronson, Tanya K.; Thoburn, John D.; Carpenter, John P.; Greenfield, Jake L.; Howe, Duncan J.; Wu, Biao; Nitschke, Jonathan R. published the artcile< Glucose Binding Drives Reconfiguration of a Dynamic Library of Urea-Containing Metal-Organic Assemblies>, Application In Synthesis of 4064-06-6, the main research area is iron urea functionalized ditopic formylpyridine helicate preparation crystal structure; host guest binding activity inclusion iron helicate saccharide mutarotation; dynamic combinatorial library; glucose binding; host-guest systems; metal-organic assemblies; supramolecular chemistry.

A bis-urea-functionalized ditopic subcomponent assembled with 2-formylpyridine and FeII, resulting in a dynamic library of metal-organic assemblies: an irregular FeII4L6 structure and three FeII2L3 stereoisomers: left- and right-handed helicates and a meso-structure. This library reconfigured in response to the addition of monosaccharide derivatives, which served as guests for specific library members, and the rate of saccharide mutarotation was also enhanced by the library. The (P) enantiomer of the FeII2L3 helical structure bound β-D-glucose selectively over α-D-glucose. As a consequence, the library collapsed into the (P)-FeII2L3 helicate following glucose addition The α-D-glucose was likewise transformed into the β-D-anomer during equilibration and binding. Thus, β-D-glucose and (P)-3 amplified each other in the product mixture, as metal-organic and saccharide libraries geared together into a single equilibrating system.

Angewandte Chemie, International Edition published new progress about Crystal structure. 4064-06-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C12H20O6, Application In Synthesis of 4064-06-6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Nizamov, Ilyas S.; Shumatbaev, Georgiy G.; Nizamov, Ilnar D.; Nikitin, Yevgeniy N.; Belov, Timur G.; Shulaeva, Marina P.; Pozdeev, Oscar K.; Batyeva, Elvira S.; Cherkasov, Rafael A. published the artcile< Chiral methylbenzylammonium salts of aryldithiophosphonic acids containing glucofuranose, allofuranose, and galactopyranose diacetonide scaffolds>, Formula: C12H20O6, the main research area is methylbenzylammonium aryldithiophosphonic acid glucofuranose allofuranose galactopyranose diacetonide antibacterial antimicrobial.

New chiral methylbenzylammonium salts of aryldithiophosphonic acids containing glucofuranose, allofuranose, and galactopyranose diacetonide substituents were obtained using (S)-(-)-α-methylbenzylamine, (R)-(+)-α-methylbenzylamine, and (R,S)-(±)-α-methylbenzylamine. Salts obtained possess antimicrobial activity.

Phosphorus, Sulfur and Silicon and the Related Elements published new progress about Antibacterial agents. 4064-06-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C12H20O6, Formula: C12H20O6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Moon, Hye Won; Maity, Ayan; Radosevich, Alexander T. published the artcile< Ancillary Tethering Influences σ3-P vs σ5-P Speciation and Enables Intermolecular S-H Oxidative Addition to Nontrigonal Phosphorus Compounds>, Formula: C19H16O, the main research area is dibenzoazepine phosphoramide preparation oxidative addition alc thiol phosphorane; crystal structure dibenzoazepine alkoxy alkylthio phosphorane; mol structure dibenzoazepine alkoxy alkylthio phosphorane.

The design and synthesis of dibenzoazepine-based nontrigonal phosphorus(III) triamide (2), bearing a peripheral ethylene bridge is described. By comparison to a compound lacking the ethylene bridge, PN(o-NMeC6H4)2 (1), the dibenzoazepine 2 is shown to exclusively form σ5-P oxidative addition products upon E-H addition (E = OR, SR) in preference to a σ3-P adduct from cooperative addition across one P-N bond. The resulting pentacoordinate phosphoranes have been characterized by multinuclear NMR spectroscopy and X-ray crystallog. DFT calculations on relative energies of σ3-P and σ5-P species indicate that the ethylene linker in 2 energetically destabilizes the σ3-P tautomer of the phosphorane product (2·[H][E]) by constraining rotation along the C-N bond, favoring formation of σ5-P phosphoranes by ring-chain tautomerism.

Organometallics published new progress about Azepines Role: PEP (Physical, Engineering or Chemical Process), PRP (Properties), RCT (Reactant), SPN (Synthetic Preparation), PROC (Process), RACT (Reactant or Reagent), PREP (Preparation) (dibenzo[b,f]azepines). 76-84-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C19H16O, Formula: C19H16O.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Wei, Ruohan; Liu, Han; Tang, Arthur H.; Payne, Richard J.; Li, Xuechen published the artcile< A Solution to Chemical Pseudaminylation via a Bimodal Glycosyl Donor for Highly Stereocontrolled α- and β-Glycosylation>, Synthetic Route of 4064-06-6, the main research area is stereoselective glycosylation pseudaminic acid bimodal glycoside donor.

A robust methodol. for the stereocontrolled chem. glycosylation of pseudaminic acid has been developed to afford both α- (axial) and β- (equatorial) glycosides reliably with complete stereoselectivity, using a common glycosyl donor (7N-Cbz/5N-azido Pse thioglycoside) simply by changing the reaction conditions. In the CH2Cl2/MeCN cosolvent, highly β-selective pseudaminylation was observed, while addition of 5.0 equiv DMF in CH2Cl2 gave the α-pseudaminosides.

Organic Letters published new progress about Glycosides Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 4064-06-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C12H20O6, Synthetic Route of 4064-06-6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Lakk-Bogath, Dora; Kripli, Balazs; Meena, Bashdar I.; Speier, Gabor; Kaizer, Jozsef published the artcile< Catalytic and stoichiometric C-H oxidation of benzylalcohols and hydrocarbons mediated by nonheme oxoiron(IV) complex with chiral tetrapyridyl ligand>, Formula: C19H16O, the main research area is oxidation hydroxylation benzylalc hydrocarbon kinetic nonheme oxoiron complex.

Bioinspired chiral iron(II) complex [((R)-(-)-N4Py*)FeII(MeCN)]2+ (1) (N4Py* = N,N-bis(2-pyridylmethyl)-1,2-di(2-pyridyl)ethylamine) has been shown to efficiently catalyze the benzylic C-H oxidation of ethylbenzene with tert-Bu hydroperoxide (TBHP), H2O2, and meta-chloroperoxybenzoic acid (mCPBA) resulting in enantiomerically enriched 1-phenylethanol up to 12.5% ee and the corresponding acetophenone, where the [FeIV(N4Py*)(O)]2+ (2) intermediate has been detected by UV/visible spectrometry. The stoichiometric oxidation of benzyl alc. and various hydrocarbon derivatives including the asym. hydroxylation of ethylbenzene with 2 has also been investigated. Detailed kinetic, and mechanistic studies (kinetic isotope effect (KIE) of 31 and 38, and Hammett correlation with ρ = -0.32 and -0.98 for PhCH2OH and PhCH3, resp., and the linear correlation between the normalized bimol. reaction rates and bond dissociation energies (BDECH)) indicated that the rate-determining step in these reactions above involves hydrogen-atom transfer between the substrate and the Fe(IV)-oxo species. The stoichiometric 2-mediated hydroxylation of ethylbenzene affords 1-phenylethanol in up to 33% ee, suggesting clear evidence for the involvement of the oxoiron(IV) species in the enantioselective step. The moderate enantioselectivity may be explained by the epimerization of the long-lived substrate radical before the rebound step (non-rebound mechanism, where kep > kreb). The kinetic resolution of the resulting chiral alc. due to its metal-based overoxidn. process into acetophenone in the catalytic metal-based ethylbenzene oxidation can be excluded.

Inorganic Chemistry Communications published new progress about Aralkyl alcohols Role: RCT (Reactant), RACT (Reactant or Reagent) (benzylalcs.). 76-84-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C19H16O, Formula: C19H16O.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Beni, Ryan; Boadi, William; Karim, Kaleh; Alnakhli, Jawzah; Alhamed, Samiyah published the artcile< Synthesis and antiproliferative activities of triphenylmethanol conjugates of leuprorelin>, Formula: C19H16O, the main research area is leuprorelin triphenylmethanol conjugate antiproliferative invasive ductal prostate carcinoma adipocyte.

Leuprorelin (LEP) is an FDA drug for breast cancer and prostate cancer treatment. There are several reported adverse effects such as transient hypertension, excessive salivation, and increased dysuria during treatment with LEP. In this study, the efficacy and toxicity of LEP were modified by using a drug delivery system to adjust the physicochem. properties. In this regard, Leuprorelin conjugates of triphenylmethanol derivatives (TPMs) were synthesized as prodrugs. Comparative antiproliferative assays showed that LEP-TPMs conjugates had significantly higher antiproliferative activities than the corresponding non-covalent phys. mixtures of the TPMs and LEP against human invasive ductal carcinoma (BT549), human prostate carcinoma (PC3), human lung cancer (A549) and mouse pre-adipocytes (3T3-L1) cells.

Open Journal of Medicinal Chemistry published new progress about Adipocyte, preadipocyte. 76-84-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C19H16O, Formula: C19H16O.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts