Tag: M.W=250-300

Nagao, Yukinori published the artcileSyntheses of leuco triphenylmethane derivatives and their UV-VIS spectra, Application of 9-Phenyl-9H-xanthen-9-ol, the publication is Nippon Kagaku Kaishi (1987), 1839-45, database is CAplus.

Leuco triphenylmethane derivatives (I; R = H, Me, OMe, NMe₂; Z = O, S, NMe, NPh) were prepared by the condensation of aromatic ketones with substituted benzenes or by Grignard reactions of aromatic ketones with bromoaryl compounds I turned into colored cations in acidic medium. UV-visible spectra in AcOH and H₂SO₄ were measured and discussed in terms of the effects of substituent R and bridging group Z. A good correlation between λ_max of the xanthene derivatives and the Hammett σ value of the substituents was observed, and the effect of the bridging group on the longest λ_max was that the bathochromic shift increased as the electron-donating ability of the bridging group decreased except for Z = S. The effects of R and Z were very similar to those of substituents on the Y band in triphenylmethane dyes having substituents on 2 rings.

Nippon Kagaku Kaishi published new progress about 596-38-3. 596-38-3 belongs to alcohols-buliding-blocks, auxiliary class Other Aromatic Heterocyclic,Benzene,Alcohol, name is 9-Phenyl-9H-xanthen-9-ol, and the molecular formula is C19H14O2, Application of 9-Phenyl-9H-xanthen-9-ol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Mukherji, Ananya published the artcileSterically Strained Bronsted Pair Catalysis by Bulky Pyridinium Salts: Direct Stereoselective Synthesis of 2-Deoxy and 2,6-Dideoxy-β-thioglycosides from Glycals, HPLC of Formula: 20880-92-6, the publication is Journal of Organic Chemistry (2021), 86(23), 17226-17243, database is CAplus and MEDLINE.

A sterically strained ionic Bronsted pair complex obtained from a sterically bulky base 2,4,6-tri-tert-butylpyridine and hydrochloric acid unusual reactivity to the anionic chloride. The complete shielding of the cationic [N-H]⁺ by the bulky ortho-tert-Bu groups weakens the possible hydrogen-bonding interactions with the chloride anion, and the [N-H]⁺···Cl^– distance is unusually longer (3.10 Å). This results in strained/frustrated electrostatic interactions between the ion-pair, thus infusing an increased reactivity in both of the ions, which results in the activation of a third mol. like thiol via hydrogen-bonding. This intriguing weak interaction-based reactivity has been utilized to develop an organocatalytic synthesis of 2-deoxy-β-thioglycosides from glycals. While the ¹H NMR studies showcase the diamagnetic activation of thiols in the presence of the catalyst, the ESR (EPR) studies reveal the generation of a radical species that suggests a possible frustrated radical pair catalysis. Besides, IR spectroscopic studies explain the intriguing influence of size/charge d. of the anion on the solvation-insusceptible, cationic [TTBPyH]⁺ and on the observed reactivity.

Journal of Organic Chemistry published new progress about 20880-92-6. 20880-92-6 belongs to alcohols-buliding-blocks, auxiliary class Other Aliphatic Heterocyclic,Chiral,Alcohol, name is ((3aS,5aR,8aR,8bS)-2,2,7,7-Tetramethyltetrahydro-3aH-bis([1,3]dioxolo)[4,5-b:4′,5′-d]pyran-3a-yl)methanol, and the molecular formula is C12H20O6, HPLC of Formula: 20880-92-6.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Saeidian, Hamid published the artcileThe first general protocol for N-monoalkylation of sulfamate esters: benign synthesis of N-alkyl Topiramate (anticonvulsant drug) derivatives, COA of Formula: C12H20O6, the publication is Journal of Sulfur Chemistry (2015), 36(5), 463-470, database is CAplus.

A novel protocol for the highly selective N-monoalkylation of the sulfamate ester moiety has been developed. This reaction proceeded efficiently using alkyl halides, benzyl halides and α-halo ketones as the electrophile in the presence of KF-Al₂O₃ as a cost-effective and robust catalyst. This approach provides new access to N-monoalkylated Topiramate (anticonvulsant drug) derivatives I (R = CH₃, C₂H₅, CH₂C₆H₅, Bn, etc.) which are potentially of great importance in medicinal chem.

Journal of Sulfur Chemistry published new progress about 20880-92-6. 20880-92-6 belongs to alcohols-buliding-blocks, auxiliary class Other Aliphatic Heterocyclic,Chiral,Alcohol, name is ((3aS,5aR,8aR,8bS)-2,2,7,7-Tetramethyltetrahydro-3aH-bis([1,3]dioxolo)[4,5-b:4′,5′-d]pyran-3a-yl)methanol, and the molecular formula is C12H20O6, COA of Formula: C12H20O6.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

In general, the hydroxyl group makes alcohols polar. Those groups can form hydrogen bonds to one another and to most other compounds. 24034-73-9, formula is C20H34O, Owing to the presence of the polar OH alcohols are more water-soluble than simple hydrocarbons. Methanol, ethanol, and propanol are miscible in water. Butanol, with a four-carbon chain, is moderately soluble. Reference of 24034-73-9

Zhou, Qi;Shi, Man;Zhang, Huihui;Zhu, Zunling research published 《 Comparative Study of the Petal Structure and Fragrance Components of the Nymphaea hybrid, a Precious Water Lily》, the research content is summarized as follows. Nymphaea hybrid, a precious water lily, is a widely-cultivated aquatic flower with high ornamental, economic, medicinal, and ecol. value; it blooms recurrently and emits a strong fragrance. In the present study, in order to understand the volatile components of N. hybrid and its relationship with petals structure characteristics, the morphologies and anatomical structures of the flower petals of N. hybrid were investigated, and volatile compounds emitted from the petals were identified. Scanning and transmission electron microscopy were used to describe petal structures, and the volatile constituents were collected using headspace solid-phase microextraction (HS-SPME) fibers and analyzed using gas chromatog. coupled with mass spectrometry (GC-MS). The results indicated that the d. and degree of protrusion and the number of plastids and osmiophilic matrix granules in the petals play key roles in emitting the fragrance. There were distinct differences in the components and relative contents of volatile compounds among the different strains of N. hybrid. In total, 29, 34, 39, and 43 volatile compounds were detected in the cut flower petals of the blue-purple type (Nh-1), pink type (Nh-2), yellow type (Nh-3) and white type (Nh-4) of N. hybrid at the flowering stage, with total relative contents of 96.78%, 97.64%, 98.56%, and 96.15%, resp. Analyses of these volatile components indicated that alkenes, alcs., and alkanes were the three major types of volatile components in the flower petals of N. hybrid. The predominant volatile compounds were benzyl alc., pentadecane, trans-α-bergamotene, (E)-β-farnesene, and (6E,9E)-6,9-heptadecadiene, and some of these volatile compounds were terpenes, which varied among the different strains. Moreover, on the basis of hierarchical cluster anal. (HCA) and principal component anal. (PCA), the N. hybrid samples were divided into four groups: alcs. were the most important volatile compounds for Nh-4 samples; esters and aldehydes were the predominant volatiles in Nh-3 samples; and ketones and alkenes were important for Nh-2 samples. These compounds contribute to the unique flavors and aromas of the four strains of N. hybrid.

24034-73-9, Geranylgeraniol is a diterpenoid that is hexadeca-2,6,10,14-tetraene substituted by methyl groups at positions 3, 7, 11 and 15 and a hydroxy group at position 1. It has a role as a plant metabolite, a volatile oil component and an antileishmanial agent. It is a diterpenoid and a polyprenol.

Geranylgeraniol, a precursor to geranylgeranylpyrophosphate, is an intermediate in the mevalonate pathway. Geranylgeraniol has been shown to prevent bone re-absorption, inhibition of osteoclast formation, and kinase activation in vitro. When working with statins, Geranylgeraniol can reduce the toxicity without inhibiting the cholesterol-producing effects. Geranylgeraniol has been documented to counteract the effects of fluvastatin by inhibiting activation of caspase-1 and production of IL-1. Additionally Geranylgeraniol has been found to induce apoptosis in HL-60 cells.
, Reference of 24034-73-9

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Simple alcohols are found widely in nature. Ethanol is the most prominent because it is the product of fermentation, a major energy-producing pathway. 24034-73-9, formula is C20H34O, Other simple alcohols, chiefly fusel alcohols, are formed in only trace amounts. More complex alcohols however are pervasive, as manifested in sugars, some amino acids, and fatty acids. , Electric Literature of 24034-73-9

Zhao, Ru;Ben, Ailing;Wei, Mengxia;Ruan, Ming;Gu, Huiyan;Yang, Lei research published 《 Essential oil obtained from Thlaspi arvense L. leaves and seeds using microwave-assisted hydrodistillation and extraction in situ by vegetable oil and its antifungal activity against Penicillium expansum》, the research content is summarized as follows. An improved approach was developed to obtain essential oil from Thlaspi arvense L. leaves (TAL) and seeds (TAS) using microwave-assisted hydrodistillation and extraction in situ by vegetable oil. Some potential parameters that affected the yield of essential oils were systematically investigated. Under the obtained optimization conditions, the maximized yields of TAL and TAS essential oils were 0.77 ± 0.02 mg/g and 2.69 ± 0.08 mg/g, resp. The results analyzed by GC-MS revealed that the main component of TAS essential oil was allyl isothiocyanate (AITC), which accounted for 44.69% of the total essential oil content. The proportion of AITC in TAL essential oil, however, was only 9.66%. Results showed that they all had significant inhibition on P. expansum, with AITC exhibiting the greatest inhibition on P. expansum. The study of antifungal activity indicates that AITC has potential application value and broad application prospects in food preservation-related fields in the future.

Electric Literature of 24034-73-9, Geranylgeraniol is a diterpenoid that is hexadeca-2,6,10,14-tetraene substituted by methyl groups at positions 3, 7, 11 and 15 and a hydroxy group at position 1. It has a role as a plant metabolite, a volatile oil component and an antileishmanial agent. It is a diterpenoid and a polyprenol.

Geranylgeraniol, a precursor to geranylgeranylpyrophosphate, is an intermediate in the mevalonate pathway. Geranylgeraniol has been shown to prevent bone re-absorption, inhibition of osteoclast formation, and kinase activation in vitro. When working with statins, Geranylgeraniol can reduce the toxicity without inhibiting the cholesterol-producing effects. Geranylgeraniol has been documented to counteract the effects of fluvastatin by inhibiting activation of caspase-1 and production of IL-1. Additionally Geranylgeraniol has been found to induce apoptosis in HL-60 cells.
, 24034-73-9.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

In general, the hydroxyl group makes alcohols polar. 24034-73-9, formula is C20H34O, Because of hydrogen bonding, alcohols tend to have higher boiling points than comparable hydrocarbons and ethers. Application In Synthesis of 24034-73-9

Zaniol, Felipe;Calisto, Jean F. F.;Cozzer, Gilberto;Ferro, Diego M.;Dias, Jonatas L.;Rodrigues, Luiz G. G.;Mazzutti, Simone;Rezende, Renan S.;Simoes, Daniel A.;Ferreira, Sandra R. S.;Dal Magro, Jacir;Oliveira, J. Vladimir research published 《 Comparative larvicidal effect of Pterodon spp. extracts obtained by different extraction methods》, the research content is summarized as follows. Pterodon spp. is a native Brazilian tree species of Fabaceae family, popularly known as sucupira. In the present study, the extraction methods of Soxhlet, supercritical fluid extraction (SFE) and ultrasound assisted extraction (UAE) were conducted at different conditions to recover compounds from “sucupira” with larvicidal activity against Aedes aegypti larvae. The influence of temperature and pressure on SFE with CO₂ was compared to Soxhlet and UAE techniques, performed with hexane and ethanol as solvents. The use of ethanol as solvent provided better yields, but lower larvicidal activity. The extraction yields obtained with CO₂ and hexane as solvents (non-polar) were similar, regardless the extraction method. Non-polar solvents showed better larvicidal activity with chances of having practical applications in fighting disease vectors. The chem. composition of these extracts presented as major components, trans-geranylgeraniol, germacrene-D-ol and caryophyllene, which showed to be responsible for the activity.

Application In Synthesis of 24034-73-9, Geranylgeraniol is a diterpenoid that is hexadeca-2,6,10,14-tetraene substituted by methyl groups at positions 3, 7, 11 and 15 and a hydroxy group at position 1. It has a role as a plant metabolite, a volatile oil component and an antileishmanial agent. It is a diterpenoid and a polyprenol.

Geranylgeraniol, a precursor to geranylgeranylpyrophosphate, is an intermediate in the mevalonate pathway. Geranylgeraniol has been shown to prevent bone re-absorption, inhibition of osteoclast formation, and kinase activation in vitro. When working with statins, Geranylgeraniol can reduce the toxicity without inhibiting the cholesterol-producing effects. Geranylgeraniol has been documented to counteract the effects of fluvastatin by inhibiting activation of caspase-1 and production of IL-1. Additionally Geranylgeraniol has been found to induce apoptosis in HL-60 cells.
, 24034-73-9.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Synthetic Route of 24034-73-9, In chemistry, an alcohol is a type of organic compound that carries at least one hydroxyl functional group (−OH) bound to a saturated carbon atom. 24034-73-9, name is (2E,6E,10E)-3,7,11,15-Tetramethylhexadeca-2,6,10,14-tetraen-1-ol, An important class of alcohols, of which methanol and ethanol are the simplest examples, includes all compounds which conform to the general formula CnH2n+1OH.

Yin, Yue;Qiu, Yan-Wei;Huang, Juan;Tobe, Stephen S.;Chen, Shan-Shan;Kai, Zhen-Peng research published 《 Enzymes in the juvenile hormone biosynthetic pathway can be potential targets for pest control》, the research content is summarized as follows. A review. BACKGROUND : Discovery of novel insecticides and targets has received global attention in recent years. Ten genes coding for enzymes involved in the juvenile hormone biosynthetic pathway of Manduca sexta were studied as potential insecticide targets. RESULTS : We determined the expression of genes encoding some critical enzymes in the JH biosynthetic pathway. Farnesol dehydrogenase (FOLD), Juvenile hormone acid O-methyltransferase (JHAMT) and Juvenile hormone epoxidase (CYP15C1) were selected as the candidate targets based on gene expression results. RNAi silencing and enzyme inhibitor tests were performed to validate whether these candidate genes could be the potential insecticide targets. The down-regulation of FOLD, JHAMT and CYP15C1 resulted in a 68%, 82% and 79% reduction in the rates of JH biosynthesis in vitro, resp. In addition, RNA interference and inhibitor studies of these enzymes following oral administration demonstrated the potential application in pest management, with respect to high mortality and effects on growth. CONCLUSION : Based on our study, FOLD, JHAMT and CYP15C1 could be potential targets for pest control as a consequence of their important roles in insect development. © 2019 Society of Chem. Industry.

24034-73-9, Geranylgeraniol is a diterpenoid that is hexadeca-2,6,10,14-tetraene substituted by methyl groups at positions 3, 7, 11 and 15 and a hydroxy group at position 1. It has a role as a plant metabolite, a volatile oil component and an antileishmanial agent. It is a diterpenoid and a polyprenol.

Geranylgeraniol, a precursor to geranylgeranylpyrophosphate, is an intermediate in the mevalonate pathway. Geranylgeraniol has been shown to prevent bone re-absorption, inhibition of osteoclast formation, and kinase activation in vitro. When working with statins, Geranylgeraniol can reduce the toxicity without inhibiting the cholesterol-producing effects. Geranylgeraniol has been documented to counteract the effects of fluvastatin by inhibiting activation of caspase-1 and production of IL-1. Additionally Geranylgeraniol has been found to induce apoptosis in HL-60 cells.
, Synthetic Route of 24034-73-9

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

With respect to acute toxicity, simple alcohols have low acute toxicities. Doses of several milliliters are tolerated. 24034-73-9, formula is C20H34O, For pentanols, hexanols, octanols and longer alcohols, LD50 range from 2–5 g/kg (rats, oral). Ethanol is less acutely toxic.All alcohols are mild skin irritants. Application of C20H34O

Zambari, Izzah Farhah;Hafid, Sitti Rahma Abdul;Muhamad, Nur Airina research published 《 Optimisation of extraction method and phytochemical compounds of green Christia vespertilionis leaves using GC-MS》, the research content is summarized as follows. Christia vespertilionis (L. f.) Bakh. f. has been widely known in treating various contagious diseases. This plant is popular among researchers and locals to have anti-inflammatory, and anti-cancer properties. There are two types of C. vespertilionis which is green and red type. The green C. vespertilionis was extensively studied by many researchers and known by the public as a cure to the cancer. This study was carried out to identify major phytochems. and optimize extraction method of green C. vespertilionis leaves in different extraction techniques (maceration and Soxhlet extraction) and solvents (methanol and ethanol) through GC-MS anal. The green C. vespertilionis leaves extract was tested using Gas Chromatog. Mass Spectrophotometer (GC-MS). The components were identified by comparing National Institute of Standards and Technol. (NIST). Based on four samples which are green C. vespertilionis leaves using maceration of methanol (GMM), maceration of ethanol (GME), Soxhlet of methanol (GSM) and Soxhlet of ethanol (GSE), seventy phytochem. compounds were identified. Thirteen major phytochem. compounds (> 4% of peak area) are acetic acid, Bu ester; 1-Butanol, 3-methyl-, acetate; 1,3-Diisobutyrin, trimethylsilyl; .alpha.-d-Mannofuranoside, methyl; 1-Tetradecene; 1-Hexadecene; 1-Octadecene; Hexanoic acid, 3-oxo-, Et ester; 4-O-Methylmannose; n-Hexadecanoic acid; Phytol; 9,12,15-Octadecatrienoic acid, (Z,Z,Z)- and Squalene. Only ten out of thirteen compounds were reported to have biol. activities. Among those samples, GMM and GSM were the most effective using correlation coefficient anal. between peak area (%) vs. real time (min) with significant difference at P < 0.001.

Application of C20H34O, Geranylgeraniol is a diterpenoid that is hexadeca-2,6,10,14-tetraene substituted by methyl groups at positions 3, 7, 11 and 15 and a hydroxy group at position 1. It has a role as a plant metabolite, a volatile oil component and an antileishmanial agent. It is a diterpenoid and a polyprenol.

Geranylgeraniol, a precursor to geranylgeranylpyrophosphate, is an intermediate in the mevalonate pathway. Geranylgeraniol has been shown to prevent bone re-absorption, inhibition of osteoclast formation, and kinase activation in vitro. When working with statins, Geranylgeraniol can reduce the toxicity without inhibiting the cholesterol-producing effects. Geranylgeraniol has been documented to counteract the effects of fluvastatin by inhibiting activation of caspase-1 and production of IL-1. Additionally Geranylgeraniol has been found to induce apoptosis in HL-60 cells.
, 24034-73-9.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

In general, the hydroxyl group makes alcohols polar. 24034-73-9, formula is C20H34O, Because of hydrogen bonding, alcohols tend to have higher boiling points than comparable hydrocarbons and ethers. Quality Control of 24034-73-9

Xu, Xiujuan;Lu, Ping;Shi, Qingzhao;Chen, Mengqi;Yang, Chunqiang;Qu, Zhan;Cui, Kai;Li, Mingzhe;He, Baojiang;Hu, Shaodong research published 《 Chemical analysis and sensory evaluation of main components in essential oil of cigar tobacco》, the research content is summarized as follows. In order to analyze the chem. components in the essential oil of cigar tobacco and to evaluate their effects, the essential oil of cigar tobacco was prepared by using subcritical extraction and mol. distillation technol. The enrichment effects of various components in the essential oil at different distillation temperatures were clarified. The main chem. components of the essential oil were analyzed by GC/MS, and the influences of mass fractions of various components in the essential oil on the sensory quality of cigarettes were further verified through sensory panel evaluation. The relationships between some aroma components and sensory evaluation indexes were studied via relevant anal. The results showed that at the distillation temperature of 60-80 °C, the mass fractions of nicotine, alkanes and long-chain aliphatic esters were reduced, and the aroma components with cigar styles were effectively enriched. The mass fractions of geranyl acetone, β-ionone, megastigmatrienone, dihydroactinidiolide, farnesyl acetone, phenylacetic acid, acetic acid, propionic acid, dihydro-β-ionone, n-hexanoic acid, 6-methyl-5-heptene-2-one, thujopsene and (E)-nerolidol in the essential oil were significantly pos. or extremely significantly pos. correlated with the quality evaluation indexes of cigarettes, including aroma, comprehensive taste, woody and honeysweet scents. Therefore, these compounds can be used as the main indexes for evaluating the quality of essential oil of cigar tobacco.

24034-73-9, Geranylgeraniol is a diterpenoid that is hexadeca-2,6,10,14-tetraene substituted by methyl groups at positions 3, 7, 11 and 15 and a hydroxy group at position 1. It has a role as a plant metabolite, a volatile oil component and an antileishmanial agent. It is a diterpenoid and a polyprenol.

Geranylgeraniol, a precursor to geranylgeranylpyrophosphate, is an intermediate in the mevalonate pathway. Geranylgeraniol has been shown to prevent bone re-absorption, inhibition of osteoclast formation, and kinase activation in vitro. When working with statins, Geranylgeraniol can reduce the toxicity without inhibiting the cholesterol-producing effects. Geranylgeraniol has been documented to counteract the effects of fluvastatin by inhibiting activation of caspase-1 and production of IL-1. Additionally Geranylgeraniol has been found to induce apoptosis in HL-60 cells.
, Quality Control of 24034-73-9

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Simple alcohols are found widely in nature. Ethanol is the most prominent because it is the product of fermentation, a major energy-producing pathway. 24034-73-9, formula is C20H34O, Other simple alcohols, chiefly fusel alcohols, are formed in only trace amounts. More complex alcohols however are pervasive, as manifested in sugars, some amino acids, and fatty acids. , Recommanded Product: (2E,6E,10E)-3,7,11,15-Tetramethylhexadeca-2,6,10,14-tetraen-1-ol

Xiong, Kangning;Chen, Yun research published 《 Supercritical carbon dioxide extraction of essential oil from tangerine peel: Experimental optimization and kinetics modelling》, the research content is summarized as follows. In this work, tangerine peel oil extraction is carried out by applying the supercritical carbon dioxide (scCO2) extraction The effect of extraction parameters on extraction yield was discussed, at particle size of 0.2-1.0mm, temperature of 35-55°C, pressure of 10-30MPa and extraction time of 0-180min. And the response surface methodol. (RSM) with a Box-Behnken Design (BBD) was applied to obtain the optimal extraction conditions. Based on this investigation, it is indicated that the optimized operation conditions for tangerine peel oil extraction was temperature 45°C, pressure 14MPa and extraction time 147min, and the largest exptl. yield of tangerine peel oil was 1.34%. Moreover, a gas chromatog.-mass spectrometry (GC-MS) anal. was used to determine the chem. composition of tangerine peel oil. The major compounds found in the tangerine peel oil were n-hexadecanoic acid (14.62%), linoleic acid (32.3%) and oleic acid (20.42%). Finally, two kinetic models were used to correlate the exptl. results, and the parameters in both models have been optimized by simulating annealing (SA) algorithm. The results show that the overall average absolute relative deviation (AARD) values of model I and model II are 3.42% and 2.76%, resp. The AARD value of model II is smaller and the application of model II is more extensive. The extraction parameters optimization, chem. composition anal. and kinetics modeling can provide theor. basis for industrialization of extraction of tangerine peel oil.

24034-73-9, Geranylgeraniol is a diterpenoid that is hexadeca-2,6,10,14-tetraene substituted by methyl groups at positions 3, 7, 11 and 15 and a hydroxy group at position 1. It has a role as a plant metabolite, a volatile oil component and an antileishmanial agent. It is a diterpenoid and a polyprenol.

Geranylgeraniol, a precursor to geranylgeranylpyrophosphate, is an intermediate in the mevalonate pathway. Geranylgeraniol has been shown to prevent bone re-absorption, inhibition of osteoclast formation, and kinase activation in vitro. When working with statins, Geranylgeraniol can reduce the toxicity without inhibiting the cholesterol-producing effects. Geranylgeraniol has been documented to counteract the effects of fluvastatin by inhibiting activation of caspase-1 and production of IL-1. Additionally Geranylgeraniol has been found to induce apoptosis in HL-60 cells.
, Recommanded Product: (2E,6E,10E)-3,7,11,15-Tetramethylhexadeca-2,6,10,14-tetraen-1-ol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts