Tag: M.W=250-300

Chen, Li published the artcileDeveloping the large-area manganese-based catalytic ceramic membrane for peroxymonosulfate activation: Applications in degradation of endocrine disrupting compounds in drinking water, Quality Control of 80-09-1, the publication is Journal of Membrane Science (2022), 120602, database is CAplus.

Endocrine disrupting compounds (EDCs) in the aquatic systems are of growing concerns that could undermine drinking water safety. In this study, manganese (III) oxide (Mn2O3) based catalytic ceramic membrane (CCM) was developed for the activation of peroxymonosulfate (PMS), and its applicability has been tested in degrading the ten different EDCs (including bisphenol analogs (BPs)) in drinking water. The CCMs were synthesized at different calcination temperatures i.e., 850, 950, and 1150°C. Optimal performance of CCMs/PMS was achieved at a higher degree of calcination. The CCMs/PMS has shown a potential to effectively degrade the EDCs at higher concentrations (mg/L) to trace levels (ng/L). The CCMs/PMS system adopted a non-radical pathway of degrading the EDCs through the extensive generation of singlet oxygen (1O2), as confirmed using quenching experiments and ESR (EPR) spectroscopy. 1O2-based oxidation process showed special selectivity for the decontamination of phenols and bisphenols. The long-term performance of CCMs/PMS showed good stability in degradation of the EDCs in drinking water, also with efficient mineralization (TOC removal >55%) and negligible release of Mn (0.004 wt%Mn/min). CCMs/PMS system also showed high potential in improving water quality by reducing the disinfection byproducts (DBPs) formation potential, highest recorded for bromodichloromethane (CHCl2Br, 100%) and lowest for dichloroacetic acids (TCAA, ∼50%). The study provided a highly efficient catalytic ceramic membrane based advanced oxidation process (AOPs) for effective degradation multiple of EDCs in drinking water, and the findings of this work can be a baseline for full-scale water treatment applications.

Journal of Membrane Science published new progress about 80-09-1. 80-09-1 belongs to alcohols-buliding-blocks, auxiliary class Ploymers, name is 4,4′-Sulfonyldiphenol, and the molecular formula is C12H10O4S, Quality Control of 80-09-1.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Koeckerling, Martin published the artcileStructural and Kinetic Considerations for the Application of the Traceless Staudinger Ligation to Future ¹⁸F Radiolabeling Using XRD and ¹⁹F NMR, Recommanded Product: ((3aS,5aR,8aR,8bS)-2,2,7,7-Tetramethyltetrahydro-3aH-bis([1,3]dioxolo)[4,5-b:4′,5′-d]pyran-3a-yl)methanol, the publication is International Journal of Chemical Kinetics (2018), 50(1), 31-40, database is CAplus.

A 4-fluorobenzoate-functionalized phosphane was synthesized and reacted with different azides using the traceless Staudinger ligation as a representative sample reaction for future radiolabeling purposes with short-lived radionuclides like fluorine-18. For this purpose, the reaction rate was evaluated at different temperatures The effect of starting material concentrations and the influence of the steric effect coming from the applied azides were investigated. ¹⁹F NMR was used to determine the reaction half-live (τ_1/2) and the reaction rate constant (k_obs) of this ligation under mild reaction conditions in a water-acetonitrile mixture Furthermore, the phosphane key compound I (orthorhombic, space group Pna2₁, a = 18.6363(9), b = 8.3589(4), c = 18.5480(9) Å, V = 2889.4(2) ų, Z = 8, D_obs = 1.277 g/cm³), which acts as starting material for all subsequent syntheses, and the fluorine-containing phosphane II (monoclinic, space group P2₁/c, a = 8.321(2), b = 16.160(4), c = 14.940(4) Å, β = 99.51(1)°, V = 1981.4(8) ų, Z = 4, D_obs = 1.342 g/cm³) were analyzed by single-crystal XRD.

International Journal of Chemical Kinetics published new progress about 20880-92-6. 20880-92-6 belongs to alcohols-buliding-blocks, auxiliary class Other Aliphatic Heterocyclic,Chiral,Alcohol, name is ((3aS,5aR,8aR,8bS)-2,2,7,7-Tetramethyltetrahydro-3aH-bis([1,3]dioxolo)[4,5-b:4′,5′-d]pyran-3a-yl)methanol, and the molecular formula is C12H20O6, Recommanded Product: ((3aS,5aR,8aR,8bS)-2,2,7,7-Tetramethyltetrahydro-3aH-bis([1,3]dioxolo)[4,5-b:4′,5′-d]pyran-3a-yl)methanol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Dong, Zhe published the artcileMetallaphotoredox-enabled deoxygenative arylation of alcohols, HPLC of Formula: 20880-92-6, the publication is Nature (London, United Kingdom) (2021), 598(7881), 451-456, database is CAplus and MEDLINE.

Metal-catalyzed cross-couplings are a mainstay of organic synthesis and are widely used for the formation of C-C bonds, particularly in the production of unsaturated scaffolds1. However, alkyl cross-couplings using native sp3-hybridized functional groups such as alcs. remain relatively underdeveloped2. In particular, a robust and general method for the direct deoxygenative coupling of alcs. would have major implications for the field of organic synthesis. A general method for the direct deoxygenative cross-coupling of free alcs. must overcome several challenges, most notably the in situ cleavage of strong C-O bonds3, but would allow access to the vast collection of com. available, structurally diverse alcs. as coupling partners4. Authors report herein a metallaphotoredox-based cross-coupling platform in which free alcs. are activated in situ by N-heterocyclic carbene salts for carbon-carbon bond formation with aryl halide coupling partners. This method is mild, robust, selective and most importantly, capable of accommodating a wide range of primary, secondary and tertiary alcs. as well as pharmaceutically relevant aryl and heteroaryl bromides and chlorides. The power of the transformation has been demonstrated in a number of complex settings, including the late-stage functionalization of Taxol and a modular synthesis of Januvia, an antidiabetic medication. This technol. represents a general strategy for the merger of in situ alc. activation with transition metal catalysis.

Nature (London, United Kingdom) published new progress about 20880-92-6. 20880-92-6 belongs to alcohols-buliding-blocks, auxiliary class Other Aliphatic Heterocyclic,Chiral,Alcohol, name is ((3aS,5aR,8aR,8bS)-2,2,7,7-Tetramethyltetrahydro-3aH-bis([1,3]dioxolo)[4,5-b:4′,5′-d]pyran-3a-yl)methanol, and the molecular formula is C12H20O6, HPLC of Formula: 20880-92-6.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Melough, Melissa M. published the artcileDiet quality and exposure to endocrine-disrupting chemicals among US adults, Quality Control of 80-09-1, the publication is Environmental Research (2022), 113049, database is CAplus and MEDLINE.

Human exposure to endocrine-disrupting chems. (EDCs) may increase risk for chronic disease. Diet is a significant source of EDC exposure, yet healthy diets recommended for chronic disease prevention have not been thoroughly examined for associations with EDC exposure. Using data from the National Health and Nutrition Examination Survey 2013-2016, we examined associations of dietary patterns with exposure to non-persistent EDCs potentially consumed through diet. EDCs were measured in spot urine samples. Diet was assessed using 24-h recalls. Multivariable linear regression was used to examine associations of three healthy diet scores [Healthy Eating Index (HEI), relative Mediterranean Diet (rMED), and Dietary Approaches to Stop Hypertension] and fast-food consumption with EDCs. In fully adjusted models, no diet was associated with exposure to the bisphenols, phthalates, or polycyclic aromatic hydrocarbons examined A 1-point increase in rMED (of 18 possible points) was associated with 2.7% (95% CI: 1.7%, 3.8%) greater urinary nitrate. A 10-point increase in HEI (of 100 possible points) was associated with 5.3% (95% CI: 2.8%, 7.9%) greater nitrate and 6.8% (95% CI: 4.5%, 9.2%) greater perchlorate. Because perchlorate and nitrate can disrupt thyroid hormone production, we conducted an exploratory anal. to examine whether these chems. mediate an association between diet and thyroid hormones. A 10-point increase in HEI was associated with 0.6% reduced serum total thyroxine (95% CI: 1.7%, 0.5%) among all adults, with 57.5% of the effect explained by perchlorate. Nitrate mediated an association of rMED with modestly reduced total triiodothyronine among females. Most EDCs examined had no association with the diets evaluated, indicating that recommended healthy diets were not protective against EDC exposures. As observed with two thyroid antagonists, some recommended diets may increase EDC exposures and related adverse health outcomes. Addnl. work should identify effective food production and processing practices to reduce dietary exposures to potentially harmful EDCs.

Environmental Research published new progress about 80-09-1. 80-09-1 belongs to alcohols-buliding-blocks, auxiliary class Ploymers, name is 4,4′-Sulfonyldiphenol, and the molecular formula is C12H10O4S, Quality Control of 80-09-1.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Vorcakova, Katarina published the artcileSynthesis and characterization of new inhibitors of cholinesterases based on N-phenylcarbamates: In vitro study of inhibitory effect, type of inhibition, lipophilicity and molecular docking, Formula: C12H20O6, the publication is Bioorganic Chemistry (2018), 280-289, database is CAplus and MEDLINE.

Based on current treatment of Alzheimer’s disease, where the carbamate inhibitor Rivastigmine is used, two series of carbamate derivatives were prepared: (i) N-phenylcarbamates with addnl. carbamate group and (ii) N-phenylcarbamates with monosaccharide moiety. All compounds were tested for the inhibitory effect on both of the cholinesterases, elec. eel acetylcholinesterase (eeAChE) and butyrylcholinesterase from equine serum (eqBChE) and the inhibitory activity (expressed as IC₅₀ values) was compared with that of the established drugs Galanthamine and Rivastigmine. The compounds with two carbamate groups revealed higher inhibitory efficiency on both cholinesterases in compared with monosaccharide derived carbamates and with Rivastigmine. The significant decrease of inhibitory efficiency on eqBChE (also for eeAChE but in less manner) was observed after deacetalization of monosaccharide. Moreover, the type of inhibitory mechanism of five chosen compounds was studied. It was found, that compounds with two carbamate groups act presumably via a mixed inhibitory mechanism and the compounds with monosaccharide moiety act as noncompetitive inhibitors. The lipophilicity of tested compounds was determined using partition coefficient Specific positions of the inhibitors in the binding sites of cholinesterases were determined using mol. modeling and the results indicate the importance of phenylcarbamate orientation in the catalytic gorges of both enzymes.

Bioorganic Chemistry published new progress about 20880-92-6. 20880-92-6 belongs to alcohols-buliding-blocks, auxiliary class Other Aliphatic Heterocyclic,Chiral,Alcohol, name is ((3aS,5aR,8aR,8bS)-2,2,7,7-Tetramethyltetrahydro-3aH-bis([1,3]dioxolo)[4,5-b:4′,5′-d]pyran-3a-yl)methanol, and the molecular formula is C8H10S, Formula: C12H20O6.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Xie, Yun published the artcileExcited-state hydroxide ion transfer from a model xanthenol photobase, Category: alcohols-buliding-blocks, the publication is Journal of Physical Chemistry B (2015), 119(6), 2498-2506, database is CAplus and MEDLINE.

This article reports a study of excited-state hydroxide ion release from a model xanthenol photobase, XanOH. The driving force for the reaction was tuned using solvent mixtures with varying water/acetonitrile ratios, and the kinetics of the reaction was monitored using ultrafast pump-probe spectroscopy. The intrinsic barrier for the heterolysis was evaluated using Marcus and bond-energy bond-order (BEBO) models. The obtained value (ΔG^#_o = 10.17-10.80 kcal/mol) is significantly higher than the intrinsic barriers found for the proton release from previously studied photoacids. These results were discussed in terms of the difference in structures of solvated H⁺ and OH^– ions.

Journal of Physical Chemistry B published new progress about 596-38-3. 596-38-3 belongs to alcohols-buliding-blocks, auxiliary class Other Aromatic Heterocyclic,Benzene,Alcohol, name is 9-Phenyl-9H-xanthen-9-ol, and the molecular formula is C9H10O3S, Category: alcohols-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Yu, Wan-Lei published the artcileDehydrogenative Silylation of Alkenes for the Synthesis of Substituted Allylsilanes by Photoredox, Hydrogen-Atom Transfer, and Cobalt Catalysis, Computed Properties of 20880-92-6, the publication is Angewandte Chemie, International Edition (2019), 58(32), 10941-10945, database is CAplus and MEDLINE.

A synergistic catalytic method combining photoredox catalysis, hydrogen-atom transfer, and proton-reduction catalysis for the dehydrogenative silylation of alkenes was developed. With this approach, a highly concise route to substituted allylsilanes has been achieved under very mild reaction conditions without using oxidants. This transformation features good to excellent yields, operational simplicity, and high atom economy. Based on control experiments, a possible reaction mechanism is proposed.

Angewandte Chemie, International Edition published new progress about 20880-92-6. 20880-92-6 belongs to alcohols-buliding-blocks, auxiliary class Other Aliphatic Heterocyclic,Chiral,Alcohol, name is ((3aS,5aR,8aR,8bS)-2,2,7,7-Tetramethyltetrahydro-3aH-bis([1,3]dioxolo)[4,5-b:4′,5′-d]pyran-3a-yl)methanol, and the molecular formula is C18H16N2O6, Computed Properties of 20880-92-6.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Ding, Haohao published the artcileA phosphorus/sulfur-containing compound toward simultaneously endowing epoxy resin with good flame retardancy and high transparency, Computed Properties of 80-09-1, the publication is Journal of Applied Polymer Science (2022), 139(26), e52431, database is CAplus.

A phosphorus/sulfur-containing compound (sulfonylbis(3,1-phenylene) bis(diphenyl-phosphinate), named as SBPDPP) is designed and synthesized by nucleophilic substitution reaction between diphenylphosphinyl chloride and 4,4-dihydroxydiphenylsulfone, and its chem. structure is verified by Fourier transform IR, ¹H and ³¹P NMR. The incorporation of SBPDPP accelerates the curing process but decreases the glass transition temperature and the crosslinking d. of the epoxy resin (EP). The cured EP with 6 wt% SBPDPP passes UL-94 V0 rating and gives limited oxygen index value of 38.8%, meanwhile maintaining 90% of the transmittance of the pure EP. Its peak heat release rate, total heat release, total smoke production, and total smoke rate are reduced by 40.8%, 42.0%, 26.3%, and 21.9% in comparison with the pure EP, demonstrating that the SBPDPP improved simultaneously the fire safety and smoke suppression. The comprehensive anal. of the char residues after cone calorimeter test and the volatile gasses during the pyrolysis demonstrates that the SBPDPP exerted dual flame retardant effect in the gas and condensed phase. The cured FREPs have promising applications that requiring flame retardancy and maintaining transparency.

Journal of Applied Polymer Science published new progress about 80-09-1. 80-09-1 belongs to alcohols-buliding-blocks, auxiliary class Ploymers, name is 4,4′-Sulfonyldiphenol, and the molecular formula is C12H10O4S, Computed Properties of 80-09-1.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Sun, Ruiting published the artcilePeanut shells-derived biochars as adsorbents for the pipette-tip solid-phase extraction of endocrine-disrupting phenols in water, milk and beverage, Formula: C12H10O4S, the publication is Journal of Chromatography A (2022), 463101, database is CAplus and MEDLINE.

In the present work, a type of biochar materials derived from carbonizing peanut shells were obtained and employed as the adsorbents of pipet-tip solid-phase extraction (PT-SPE) for the enrichment and determination of six endocrine-disrupting phenols (EDPs) in combination with high-performance liquid chromatog. equipped with UV detector (HPLC-UV). Abundant aliphatic and aromatic carbon structures and functional groups from polar heteroatoms (N, O, S) were distributed in the low-cost and eco-friendly peanut shells-derived biochar materials and were favorable for the enrichment of target EDPs. Moreover, the theor. calculation based on d. functional theory (DFT) proved that the effective enrichment of EDPs in aqueous samples benefited from the effective adsorption on the peanut shells-derived biochar materials. The exptl. factors influencing the extraction efficiency were investigated, including adsorbent amount, aspirating/dispensing cycles, the type of elution solvent and elution times, salt addition, sample solution pH and type and volume of washing solvent. Under the optimal conditions, the proposed PT-SPE method exhibited good linear relationship (R2 > 0.993) in the range of 0.5-400μg/L and low limits of detections (LODs) from 0.25 to 2.5μg/L, as well as good precision and accuracy with relative standard deviations (RSDs) of 0.3%-13.2% and recoveries of 83.5%-117.1%. Finally, the biochars-based miniaturized pretreatment method was employed for the determination of six EDPs in bottled water, milk, tea beverage and disposal plastic bag soaked solution with recoveries from 77.5% to 116.5%.

Journal of Chromatography A published new progress about 80-09-1. 80-09-1 belongs to alcohols-buliding-blocks, auxiliary class Ploymers, name is 4,4′-Sulfonyldiphenol, and the molecular formula is C16H24BF4Ir, Formula: C12H10O4S.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Zhao, Jiacheng published the artcileCellular Uptake and Movement in 2D and 3D Multicellular Breast Cancer Models of Fructose-Based Cylindrical Micelles That Is Dependent on the Rod Length, Application In Synthesis of 20880-92-6, the publication is ACS Applied Materials & Interfaces (2016), 8(26), 16622-16630, database is CAplus and MEDLINE.

While the shape effect of nanoparticles on cellular uptake has been frequently studied, no consistent conclusions are available currently. The controversy mainly focuses on the cellular uptake of elongated (i.e., filaments or rod-like micelles) as compared to spherical (i.e., micelles and vesicles) nanoparticles. So far, there is no clear trend that proposes the superiority of spherical or nonspherical nanoparticles with conflicting reports available in the literature. One of the reasons is that these few reports available deal with nanoparticles of different shapes, surface chemistries, stabilities, and aspects ratios. Here, we investigated the effect of the aspect ratio of cylindrical micelles on the cellular uptake by breast cancer cell lines MCF-7 and MDA-MB-231. Cylindrical micelles, also coined rod-like micelles, of various length were prepared using fructose-based block copolymers poly(1-O-methacryloyl-β-D-fructopyranose)-b-poly(Me methacrylate). The critical water content, temperature, and stirring rate that trigger the morphol. transition from spheres to rods of various aspect ratios were identified, allowing the generation of different kinetically trapping morphologies. High shear force as they are found with high stirring rates was observed to inhibit the formation of long rods. Rod-like micelles with length of 500-2000 nm were subsequently investigated toward their ability to translocate in breast cancer cells and penetrate into MCF-7 multicellular spheroid models. It was found that shorter rods were taken up at a higher rate than longer rods.

ACS Applied Materials & Interfaces published new progress about 20880-92-6. 20880-92-6 belongs to alcohols-buliding-blocks, auxiliary class Other Aliphatic Heterocyclic,Chiral,Alcohol, name is ((3aS,5aR,8aR,8bS)-2,2,7,7-Tetramethyltetrahydro-3aH-bis([1,3]dioxolo)[4,5-b:4′,5′-d]pyran-3a-yl)methanol, and the molecular formula is C19H21N3O3S, Application In Synthesis of 20880-92-6.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts