Tag: M.W=200-350

Bowsher, Alan W. published the artcileAnalysis of wild sunflower (Helianthus annuus L.) root exudates using gas chromatography-mass spectrometry, Recommanded Product: (3R,4R,5R)-6-(((2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hexane-1,2,3,4,5-pentaol, the main research area is Helianthus root ecol rhizosphere stress organic acid glucose.

Plant root systems mediate ecol. processes in the rhizosphere through the exudation of organic compounds Although exudate composition is thought to depend strongly on plant nutrient status, little is known about the influence of multi-nutrient stresses. In this study, we examined responses to short-term (3 d) nutrient limitation in Helianthus annuus (common sunflower), and root exudates were collected for 2, 4, or 6 h with the trap-solution method. Root exudates, analyzed by means of gas chromatog.-mass spectrometry, consisted of over 60 sugars, sugar alcs., amino acids, organic acids, and phosphates, with sugars and organic acids generally detected in the highest quantities. Twenty-five of the detected metabolites, including half of the organic acids, sugars, and sugar alcs., differed in relative abundance among the three sampling intervals, exhibiting higher abundance in sampling intervals greater than 2 h. Similarly, 24 of the detected metabolites, including half of the amino acids, phosphates, and sugar alcs., were affected by nutrient supply, with 20 exhibiting higher abundance in the high-nutrient treatment. Fumaric acid, quinic acid, and glucose were detected at significantly higher levels in the low-nutrient treatment, potentially representing an adaptive response to nutrient limitation in sunflower. However, as sampling interval exerted a strong influence on the apparent effects of nutrient supply, future studies should consider the potential impacts of sampling-interval length in comparative analyses of genotypes or treatments.

Journal of Plant Nutrition and Soil Science published new progress about Alditols Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 64519-82-0 belongs to class alcohols-buliding-blocks, name is (3R,4R,5R)-6-(((2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hexane-1,2,3,4,5-pentaol, and the molecular formula is C12H24O11, Recommanded Product: (3R,4R,5R)-6-(((2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hexane-1,2,3,4,5-pentaol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Mineo, Hitoshi published the artcileSugar alcohols enhance calcium transport from rat small and large intestine epithelium in vitro, Formula: C12H24O11, the main research area is sugar alc polyol calcium absorption intestine.

We compared the effect of a variety of sugar alcs. on calcium absorption from the rat small and large intestine in vitro. An Ussing chamber technique was used to determine the net transport of Ca across the epithelium isolated from the jejunum, ileum, cecum, and colon of rats. The concentration of Ca in the serosal and mucosal Tris buffer solution was 1.25 mM and 10 mM, resp. The Ca concentration in the serosal medium was determined after incubation for 30 min and the net Ca absorption was evaluated. The addition of 0.1-200 mM erythritol, xylitol, sorbitol, maltitol, palatinit, or lactitol to the mucosal medium affected net Ca absorption in the intestinal preparations Differences in Ca transport were observed between portions of the intestine, but not between sugar alcs. tested. We concluded that sugar alcs. directly affect the epithelial tissue and promote Ca absorption from the small and large intestine ire vitro.

Digestive Diseases and Sciences published new progress about Alditols Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 64519-82-0 belongs to class alcohols-buliding-blocks, name is (3R,4R,5R)-6-(((2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hexane-1,2,3,4,5-pentaol, and the molecular formula is C12H24O11, Formula: C12H24O11.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Allan, Matthew C. published the artcileEffects of sugars and sugar alcohols on the gelatinization temperature of wheat starch, HPLC of Formula: 64519-82-0, the main research area is wheat ribose arabinose xylose xylitol gelatinization temperature.

The effects of nineteen sugars and sugar alcs. on the gelatinization temperature (Tgel) of wheat starch were investigated. Starch Tgels in sweetener solutions were determined using differential scanning calorimetry; the solution and intrinsic properties of the sweeteners were then compared to the measured Tgels. The Tgel increased as sweetener concentration increased, but significant differences in Tgel were found between different sweetener types, even those containing the same number of carbons. On a molar basis, trisaccharides most increased the Tgel, while on a percent-solids basis disaccharides most increased the Tgel. Significant correlations existed between the Tgel and increasing sweetener solution water activities, solids contents, and viscosities, but these correlations were weaker when compared within similar sweetener concentrations The amount of sweetener entering the starch granule depended on the solution solids content. The glass transition temperature of the amorphous water-sweetener-starch fraction did not have a direct effect on the starch Tgel. Sweeteners with more equatorial and exocyclic hydroxyl groups tended to increase the Tgel more, indicating that sweetener stereochem. could be important. It was theorized that sweeteners increased the Tgel by forming sweetener-starch intermol. interactions in the starch amorphous regions, with supporting evidence including how sweeteners affected starch annealing and how pH affected starch-glucuronic acid interactions and measured Tgels. A machine-learning model was developed that could predict the starch Tgel in a sweetener solution within 1.6%. To date this study is the most comprehensive investigation of the effects of a broad variety of sweeteners on the gelatinization temperature of wheat starch.

Food Hydrocolloids published new progress about Alditols Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 64519-82-0 belongs to class alcohols-buliding-blocks, name is (3R,4R,5R)-6-(((2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hexane-1,2,3,4,5-pentaol, and the molecular formula is C12H24O11, HPLC of Formula: 64519-82-0.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Mayhew, Emily J. published the artcileTemporal Texture Profile and Identification of Glass Transition Temperature as an Instrumental Predictor of Stickiness in a Caramel System, Product Details of C12H24O11, the main research area is caramel system stickiness glass transition temperature temporal texture profile; caramel; glass transition; stickiness; temporal dominance of sensation; texture.

Stickiness is an important texture attribute in many food systems, but its meaning can vary by person, product, and throughout mastication. This variability and complexity makes it difficult to devise anal. tests that accurately and consistently predict sensory stickiness. Glass transition temperature (Tg) is a promising candidate for texture prediction. Our objective is to elucidate the temporal profile of stickiness in order to probe the relationship between Tg and dynamic stickiness perception. Nine caramel samples with diverse texture and thermal profiles were produced for sensory testing and differential scanning calorimetry. Sixteen trained panelists generated stickiness-relevant terms to be used in a subsequent temporal dominance of sensation (TDS) test with the same panelists. Following the TDS study, these panelists also rated samples for overall tactile and oral stickiness. Stickiness ratings were then correlated to TDS dominance parameters across the full evaluation period and within the first, middle, and final thirds of the evaluation period. Samples with temporal texture profiles dominated by tacky, stringy, and enveloping attributes consistently received the highest stickiness scores, although the correlation strength varied by time period. Tg was found to correlate well with trained panelist and consumer ratings of oral (R2trained = 0.85; R2consumer = 0.96) and tactile (R2trained = 0.78; R2consumer = 0.79) stickiness intensity, and stickiness intensity ratings decreased with Tg of completely amorphous samples. Further, glassy samples followed a different texture trajectory (brittle-cohesive-toothpacking) than rubbery samples (deformable-tacky-enveloping). These results illuminate the dynamic perception of stickiness and support the potential of Tg to predict both stickiness intensity and texture trajectory in caramel systems.

Journal of Food Science published new progress about Alditols Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 64519-82-0 belongs to class alcohols-buliding-blocks, name is (3R,4R,5R)-6-(((2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hexane-1,2,3,4,5-pentaol, and the molecular formula is C12H24O11, Product Details of C12H24O11.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Mayhew, Emily J. published the artcileGlass transition prediction strategies based on the Couchman-Karasz equation in model confectionary systems, Safety of (3R,4R,5R)-6-(((2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hexane-1,2,3,4,5-pentaol, the main research area is confectionary glass transition temperature cooking.

Our objectives were to compare the Couchman-Karasz-predicted glass transition temperature, TCK, to the measured glass transition temperature of a mixture, Tgm, of model confectionary systems and develop an empirical correction to improve the accuracy of prediction. Results showed that the original Couchman-Karasz equation fit the data better than the modified equation; although both generally overestimated Tgm. Blends containing sorbitol had the largest ΔTCKgm, where ΔTCKgm = TCK – Tgm. While Tgm varied with composition, the increase in Tgm with decreasing moisture content was linear (R̅2̅ = 0.984) and consistent across blends (4.5 ± 0.9°C/1% moisture, wb). The increase in Tgm with increasing cook temperature was best described by a polynomial model (R̅2̅ = 0.998), but adequately described by a more generalizable linear model (R̅2̅ = 0.979). Application of an empirical correction based on moisture content or cook temperature and TCK of dry ingredients reduced the average ΔTCKgm from 20.1°C and 11.3°C for modified and original equations, resp., to <5.6°C. Journal of Food Engineering published new progress about Alditols Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 64519-82-0 belongs to class alcohols-buliding-blocks, name is (3R,4R,5R)-6-(((2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hexane-1,2,3,4,5-pentaol, and the molecular formula is C12H24O11, Safety of (3R,4R,5R)-6-(((2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hexane-1,2,3,4,5-pentaol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Holm, Tobias Palle published the artcileScreening of novel excipients for freeze-dried protein formulations, Related Products of alcohols-buliding-blocks, the main research area is freeze dried protein formulation lyoprotectant stability; Excipients; Formulation development; Freeze-drying; High throughput; Image analysis; Intrinsic fluorescence spectroscopy; Protein stability; Solid state analysis.

The typical excipients used as bulking agents and lyoprotectants for freeze-drying are usually limited to only a few selected substances, such as sucrose and mannitol. Considering the sheer diversity amongst proteins, it is doubtful that this limited choice should, in every case, provide the best possible option in order to achieve the most stable product. In this work, a screening of 12 proteins with 64 excipients was conducted in order to increase the knowledge space of potential excipients. Three critical quality attributes (CQAs) of the freeze-dried products, namely the solid state, the cake appearance and the protein integrity based on changes in tryptophan fluorescence were investigated by high throughput X-ray powder diffraction, image anal. and intrinsic fluorescence spectroscopy, resp. It was found, that in some cases the excipient had a dominating influence on the CQAs, while in other cases the CQAs were primarily protein dependent, or that the CQAs were dependent on the combination of both. In the course of this investigation, a general view of potentially relevant excipients, and their interplay with various proteins, was obtained, thereby furthermore paving the way for the use of novel freeze-drying excipients.

European Journal of Pharmaceutics and Biopharmaceutics published new progress about Albumins Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 64519-82-0 belongs to class alcohols-buliding-blocks, name is (3R,4R,5R)-6-(((2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hexane-1,2,3,4,5-pentaol, and the molecular formula is C12H24O11, Related Products of alcohols-buliding-blocks.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Wang, Changyuan published the artcileEffect of storage on metabolites of brown rice, SDS of cas: 64519-82-0, the main research area is Oryza palmitoleic linoleic lauric acid cholesterol storage quality; brown rice; gas chromatography-mass spectrometry; metabolite; storage.

Storage is an essential part of brown rice circulation. During the storage process, the metabolic activity of brown rice is still ongoing, and long-term storage leads to the deterioration of brown rice. Metabolomics anal. was performed using gas chromatog.-mass spectrometry to investigate the changes in metabolites of brown rice after storage at 18°C for 12 mo. Results : In terms of quantity, sugar, fatty acids, and other metabolites in brown rice decreased after storage, and alcs., aldehydes, phenols, and amines increased. A total of 34 differential metabolites were screened. In terms of contents, carbohydrates, amino acids, and fatty acids of brown rice decreased after storage, while those of sugar alc., amines, and aldehydes increased after storage. Cluster anal. of the samples at zero storage time revealed that the metabolites expressed least became highly expressed after storage and those expressed highly became low after storage. Metabolic pathway anal. showed that storage significantly influenced the lipid metabolism in brown rice. Palmitoleic acid, cholesterol, linoleic acid, and lauric acid are four key metabolites in lipid metabolism during storage of brown rice. Storage has the greatest effect on lipids. Storage caused a ‘reverse change’ in the metabolites content of brown rice. The results obtained may help in understanding the changes in metabolites profile and delaying of the quality deterioration of brown rice during storage.

Journal of the Science of Food and Agriculture published new progress about Alcohols Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 64519-82-0 belongs to class alcohols-buliding-blocks, name is (3R,4R,5R)-6-(((2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hexane-1,2,3,4,5-pentaol, and the molecular formula is C12H24O11, SDS of cas: 64519-82-0.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Minh, Nguyen Phuoc published the artcileInvestigation of instant soluble herb tea production from lotus (Nelumbo Nucifera) rhizome, Safety of (3R,4R,5R)-6-(((2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hexane-1,2,3,4,5-pentaol, the main research area is nelumbo soluble herb tea rhizome.

Rhizome of Nelumbo nucifera is known to contain different bioactive phytochem. constituents. The rhizomes are used as popular health food. Lotus rhizomes are composed of proteins, fats, carbohydrates and minerals and are good source of energy. The lotus rhizomes are popularly used as vegetables. The lotus rhizomes need to be exploited for the development of value added products. We investigated a production of instant soluble herb tea from lotus root by investigating the raw lotus root, method of extraction and spray drying to get an optimal processing protocol for herb tea production Our results showed that raw lotus root should be chopped and freeze-dried to 8% moisture; solvent for extraction of lotus root herb tea should be 30% ethanol: 1% acetic acid; ratio of solvent to material should be 8:1 in 24 h at 70°C by deep soaking. Spray drying conditions to get herb tea powder should be 6% maltodextrin as carrier; 140°C as drying temperature; 250 mL/h as volume of input feeding for spraying, 8% of isomalt as supplementation.

Journal of Pharmaceutical Sciences and Research published new progress about Alkaloids Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 64519-82-0 belongs to class alcohols-buliding-blocks, name is (3R,4R,5R)-6-(((2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hexane-1,2,3,4,5-pentaol, and the molecular formula is C12H24O11, Safety of (3R,4R,5R)-6-(((2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hexane-1,2,3,4,5-pentaol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Gonulalan, Ekrem M. published the artcileMetabolomics and proteomics profiles of some medicinal plants and correlation with BDNF activity, Application of (3R,4R,5R)-6-(((2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hexane-1,2,3,4,5-pentaol, the main research area is Valeriana Melissa Passiflora BDNF neuroblastoma cell metabolomics proteomics; BDNF; GC–MS; LC-qTOF-MS; Medicinal plants; Metabolomics; Proteomics.

Identification of the low abundance of phytochems. in plant extracts is very difficult. Pharmacol. activity observed in such plants is not due to a single compound In most cases, plant extracts show activity based on synergistic or antagonistic effects. Therefore, the idea of a holistic approach is more rational. This study was planned to compare the metabolomics and proteomics profiles of Valeriana officinalis L.(Valerianaceae), Melissa officinalis L.(Lamiaceae), Hypericum perforatum L.(Hypericaceae) and Passiflora incarnata L.(Passifloraceae) used in sedative anxiolytic and sleep disorders. Integrated omics analyses were used to provide a better understanding of the effect of plant extracts on the brain-derived neurotrophic factor (BDNF) expression levels on the SH-SY5Y cell line by a holistic approach. Metabolomic profiling of the plants was performed using the GC-MS and LC-qTOF-MS systems, and the proteomics anal. using the LC-qTOF-MS system after trypsin digestion. The Human BDNF Quantikine ELISA kit was utilized to test BDNF expression activity on the SH-SY5Y cell line. The investigated plant extracts showed a significant increase in BDNF expression (p < 0.05). M. officinalis was found as the most active extract According to the correlation analyses between BDNF activity and metabolomics or proteomics level, 94 metabolites had a pos. correlation while 23 metabolites had a highly neg. correlation; those for proteins are 24 and 6, resp. The multivariate data anal. revealed a similar metabolomics profile of H. perforatum and P. incarnata, which also had a similar activity profile. Remarkably, all the primary metabolites belonging to the Krebs Cycle (citric acid, fumaric acid, succinic acid, pyruvic acid, malic acid and citramalic acid, an analog of malic acid) were pos. correlated with BDNF activity. Secondary metabolites with a high BDNF expression belonged to flavonoids, xanthone, coumarines, tannin, naphtalenes, terpenoids and carotenoid skeleton. Two proteins from the cytochrome P 450 family (P 450 71B11 and P 450 94B3) were pos. correlated with BDNF activity. Employing omics technologies in the plant research area will offer a better understanding of the role of plant extracts and may lead to the discovery of new compounds with specific activity. Phytomedicine published new progress about Alkaloids Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 64519-82-0 belongs to class alcohols-buliding-blocks, name is (3R,4R,5R)-6-(((2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hexane-1,2,3,4,5-pentaol, and the molecular formula is C12H24O11, Application of (3R,4R,5R)-6-(((2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hexane-1,2,3,4,5-pentaol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Fausto, Catia published the artcileDifferential olive grove management regulates the levels of primary metabolites in xylem sap, Formula: C12H24O11, the main research area is octadecylglycerol gluconolactone xylem metabolite Olea.

Aims: The conventional management adopted in many Mediterranean olive orchards makes them more vulnerable to climate change and attacks by pathogens, due to the decreased chem. plant defenses. In this scenario, a metabolomic anal. was carried out on the xylem sap (Xsap) of olive plants (Olea europaea L.) grown in the Salento peninsula (Italy). Trials were carried out in two olive groves, one organically and one conventionally managed (controls), successively both converted to sustainable management (i.e. frequent light pruning, soil and foliar fertilization, cover crops). The Xsap was extracted from the shoots of olive plants using a Scholander pressure chamber pressurized with N2 and gas chromatog.-mass spectrometry metabolite profiling was performed in the Xsap. An untargeted gas chromatog. mass spectrometry (GC-MS) based metabolomic anal. of primary metabolites (including underivatized volatiles) of the Xsap revealed relative abundances of 153 identified metabolites and 336 unknown features across the 12 samples from four groups of samples. Among them, more than half were involved in the primary metabolism Many of the compounds with increased levels under sustainable management (such as amino acids, soluble sugars, sugar alcs.) have a well-known role as osmoprotectants or are involved in plant defense, growth and development during stress or recovery stages. Sustainable management in olive groves can increase the ability of plants to overcome environmental stressors and enhance ecosystem balance.

Plant and Soil published new progress about Amino acids Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 64519-82-0 belongs to class alcohols-buliding-blocks, name is (3R,4R,5R)-6-(((2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hexane-1,2,3,4,5-pentaol, and the molecular formula is C12H24O11, Formula: C12H24O11.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts