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Bruna, Roberto E. team published research on Proceedings of the National Academy of Sciences of the United States of America in 2021 | 527-07-1

527-07-1, Sodium Gluconate is the sodium salt of gluconic acid with chelating property. Sodium gluconate chelates and forms stable complexes with various ions, preventing them from engaging in chemical reactions.
Sodium gluconate is an organic sodium salt having D-gluconate as the counterion. It has a role as a chelator. It contains a D-gluconate.
D-Gluconic acid sodium salt is a glycol ether that is used as an injection solution. It has been shown to have antibacterial efficacy against wild-type strains of bacteria such as Escherichia coli, Pseudomonas aeruginosa, and Staphylococcus aureus. The in vitro antimicrobial action of D-gluconic acid sodium salt was found to be due to its ability to inhibit bacterial growth by interfering with the synthesis of DNA. D-gluconic acid sodium salt also has been shown to have antihypertensive effects in rats through the inhibition of angiotensin II type 1 receptor (AT1) signaling pathway and erythrocyte proliferation. This drug also has been shown to bind benzalkonium chloride and x-ray diffraction data show that it is crystalline in nature. The analytical method for determining the concentration of D-gluconic acid sodium salt is by electrochemical impedance, Synthetic Route of 527-07-1

In general, the hydroxyl group makes alcohols polar. Those groups can form hydrogen bonds to one another and to most other compounds. 527-07-1, formula is C6H11NaO7, Owing to the presence of the polar OH alcohols are more water-soluble than simple hydrocarbons. Methanol, ethanol, and propanol are miscible in water. Butanol, with a four-carbon chain, is moderately soluble. Synthetic Route of 527-07-1

Bruna, Roberto E.;Kendra, Christopher G.;Groisman, Eduardo A.;Pontes, Mauricio H. research published 《 Limitation of phosphate assimilation maintains cytoplasmic magnesium homeostasis》, the research content is summarized as follows. Phosphorus (P) is an essential component of core biol. mols. In bacteria, P is acquired mainly as inorganic orthophosphate (Pi) and assimilated into ATP (ATP) in the cytoplasm. Although P is essential, excess cytosolic Pi hinders growth. We now report that bacteria limit Pi uptake to avoid disruption of Mg2+-dependent processes that result, in part, from Mg2+ chelation by ATP. We establish that the MgtC protein inhibits uptake of the ATP precursor Pi when Salmonella enterica serovar Typhimurium experiences cytoplasmic Mg2+ starvation. This response prevents ATP accumulation and overproduction of rRNA that together ultimately hinder bacterial growth and result in loss of viability. Even when cytoplasmic Mg2+ is not limiting, excessive Pi uptake increases ATP synthesis, depletes free cytoplasmic Mg2+, inhibits protein synthesis, and hinders growth. Our results provide a framework to understand the mol. basis for Pi toxicity. Furthermore, they suggest a regulatory logic that governs P assimilation based on its intimate connection to cytoplasmic Mg2+ homeostasis.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Andrews, Danielle team published research on European Journal of Pharmaceutics and Biopharmaceutics in 2021 | 527-07-1

Andrews, Danielle;Salunke, Smita;Cram, Anne;Bennett, Joanne;Ives, Robert S.;Basit, Abdul W.;Tuleu, Catherine research published 《 Bitter-blockers as a taste masking strategy: A systematic review towards their utility in pharmaceuticals》, the research content is summarized as follows. A review. Acceptable palatability of an oral dosage form is crucial to patient compliance. Excipients can be utilized within a formulation to mask the bitterness of a drug. One such category is the bitter-blockers. This term is used inconsistently within the literature and has historically been used to describe any additive which alters the taste of an unpleasant compound This defines a bitter-blocker as a compound which interacts with the mol. pathway of bitterness at a taste-cell level and compiles data obtained from publication screening of such compounds Here, a novel scoring system is created to assess their potential utility in a medicinal product using factors such as usability, safety, efficacy and quality of evidence to understand their taste-masking ability. Sodium acetate, sodium gluconate and adenosine 5′ monophophate each have a good usability and safety profile and are generally regarded as safe and have shown evidence of bitter-blocking in human sensory panels. These compounds could offer a much needed option to taste-mask particularly aversive medicines where traditional methods alone are insufficient.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Arelli, Vijayalakshmi team published research on Bioresource Technology in 2021 | 527-07-1

Simple alcohols are found widely in nature. Ethanol is the most prominent because it is the product of fermentation, a major energy-producing pathway. 527-07-1, formula is C6H11NaO7, Other simple alcohols, chiefly fusel alcohols, are formed in only trace amounts. More complex alcohols however are pervasive, as manifested in sugars, some amino acids, and fatty acids. , Recommanded Product: Sodium Gluconate

Arelli, Vijayalakshmi;Mamindlapelli, Naveen Kumar;Juntupally, Sudharshan;Begum, Sameena;Anupoju, Gangagni Rao research published 《 Solid-state anaerobic digestion of sugarcane bagasse at different solid concentrations: Impact of bio augmented cellulolytic bacteria on methane yield and insights on microbial diversity》, the research content is summarized as follows. This study investigated the impact of the potential cellulose degrading bacteria that could be bioaugmented in the solid-state anaerobic digestion (SSAD) of bagasse to enhance the methane yield. The prospective anaerobic cellulose degrading bacteria was isolated from the soil. SSAD experiments were organized with & without bioaugmentation with a substrate total solid (TS) of 25%, 30%, 40% and 50% at an optimized feed to microorganism (F/M) ratio of 1:1. The maximum yield of 0.44 L CH4/ (g VS added) was obtained from bioaugmented bagasse at a TS of 40% whereas it was 0.34 L CH4/(g VS added) for non-bioaugmented bagasse. The isolated bacterial strain was identified that belongs species Pseudomonas of Gamma Proteobacteria which exhibited good cellulolytic activity. Metagenomic studies found 90% of archaeal microorganisms affiliated to Methanosaeta, a strict acetoclastic methanogen.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Bai, Jing team published research on Materials Research Express in 2021 | 527-07-1

Application of C6H11NaO7, In chemistry, an alcohol is a type of organic compound that carries at least one hydroxyl functional group (−OH) bound to a saturated carbon atom. 527-07-1, name is Sodium Gluconate, An important class of alcohols, of which methanol and ethanol are the simplest examples, includes all compounds which conform to the general formula CnH2n+1OH.

Bai, Jing;Zhang, Yue;Xu, Chuanmeng;Sun, Chao;Liu, Huan;Lu, Mengmeng;Shao, Yi;Chu, Chenglin;Xue, Feng research published 《 Preparation and characterization of antibacterial oxide film with deposited silver on Al alloy》, the research content is summarized as follows. Aluminum (Al) alloy products are widely used in people′s lives, while the existence and breeding of microorganisms on their surface cannot meet the health criteria and even may harm human health. In the present study, we successfully prepared the antibacterial oxide film on the 6063 Al alloy specimens by direct-current anodizing followed by Ag element depositing and the hole sealing process. The results suggested that compared with the Al substrate, the wear resistance of the obtained film was increased to 0.79, and the corrosion resistance was significantly improved. The antibacterial rate against Escherichia coli could be achieved as 94.38 ± 3.23%, and the adhesion force between the film and substrate was about 11 N. With the increase of the deposition time, the surface color of samples was gradually darkened, and meanwhile, the surface became uniform again without particles eventually. Energy dispersive spectroscopy (EDS) results showed the silver element was deposited on the surface and at the bottom of the porous oxide layer, and the amount of silver also increased with prolonging the deposition time. Moreover, XPS anal. results on the surface showed the deposited silver element existed in the form of the ion and elemental substance, which indicated that reduction reaction of Ag⁺ appeared on the oxide film surface.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

The new and interesting world of chemistry: the extended application of 527-07-1

Computed Properties of 527-07-1, Sodium Gluconate is the sodium salt of gluconic acid with chelating property. Sodium gluconate chelates and forms stable complexes with various ions, preventing them from engaging in chemical reactions.
Sodium gluconate is an organic sodium salt having D-gluconate as the counterion. It has a role as a chelator. It contains a D-gluconate.
D-Gluconic acid sodium salt is a glycol ether that is used as an injection solution. It has been shown to have antibacterial efficacy against wild-type strains of bacteria such as Escherichia coli, Pseudomonas aeruginosa, and Staphylococcus aureus. The in vitro antimicrobial action of D-gluconic acid sodium salt was found to be due to its ability to inhibit bacterial growth by interfering with the synthesis of DNA. D-gluconic acid sodium salt also has been shown to have antihypertensive effects in rats through the inhibition of angiotensin II type 1 receptor (AT1) signaling pathway and erythrocyte proliferation. This drug also has been shown to bind benzalkonium chloride and x-ray diffraction data show that it is crystalline in nature. The analytical method for determining the concentration of D-gluconic acid sodium salt is by electrochemical impedance, 527-07-1.

Computed Properties of 527-07-1, In chemistry, an alcohol is a type of organic compound that carries at least one hydroxyl functional group (−OH) bound to a saturated carbon atom. 527-07-1, name is Sodium Gluconate, An important class of alcohols, of which methanol and ethanol are the simplest examples, includes all compounds which conform to the general formula CnH2n+1OH.

Evolution of texture and strain in Sn coating with Cr addition and its effect on the coating corrosion behavior
Sn-Cr coatings with different amounts of Cr (∼1.3-5.5 wt%) were electrodeposited over mild steel substrate. Addition of Cr altered the coating morphol. from less compact and columnar for pristine Sn coating to relatively more compact and globular for Sn-Cr coatings. Incorporation of Cr led to reduction in crystallite sizes, increase in coating strain, and enhancement in Sn crystal growth along {011} and {112} planes. Microstructural characterization revealed the presence of Cr at the grain boundaries and formation of Sn and Sn-Cr grains in the coating microstructure. Corrosion measurements conducted using the Tafel polarization and electrochem. impedance spectroscopy revealed that incorporation of minor amounts of Cr leads to significant enhancement in the corrosion resistance property of the coatings when compared to the pristine Sn coating. When compared to the pristine Sn coating, the Sn-1.3 wt% Cr coating exhibited a 40% reduction in the corrosion c.d. value. The corrosion resistance properties however deteriorated for Sn-Cr coatings with higher Cr content (3.3 and 5.4 wt%). Reduction in the corrosion rate for lower Cr additions was attributed to enhancement in the grain boundary fraction and segregation of Cr to the grain boundaries. Enhancement in the corrosion rate for higher Cr addition was attributed mainly to increase in the coating strain.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts