Synthetic Route of 527-07-1, Sodium Gluconate is the sodium salt of gluconic acid with chelating property. Sodium gluconate chelates and forms stable complexes with various ions, preventing them from engaging in chemical reactions.
Sodium gluconate is an organic sodium salt having D-gluconate as the counterion. It has a role as a chelator. It contains a D-gluconate.
D-Gluconic acid sodium salt is a glycol ether that is used as an injection solution. It has been shown to have antibacterial efficacy against wild-type strains of bacteria such as Escherichia coli, Pseudomonas aeruginosa, and Staphylococcus aureus. The in vitro antimicrobial action of D-gluconic acid sodium salt was found to be due to its ability to inhibit bacterial growth by interfering with the synthesis of DNA. D-gluconic acid sodium salt also has been shown to have antihypertensive effects in rats through the inhibition of angiotensin II type 1 receptor (AT1) signaling pathway and erythrocyte proliferation. This drug also has been shown to bind benzalkonium chloride and x-ray diffraction data show that it is crystalline in nature. The analytical method for determining the concentration of D-gluconic acid sodium salt is by electrochemical impedance, 527-07-1.
Synthetic Route of 527-07-1, In chemistry, an alcohol is a type of organic compound that carries at least one hydroxyl functional group (−OH) bound to a saturated carbon atom. 527-07-1, name is Sodium Gluconate, An important class of alcohols, of which methanol and ethanol are the simplest examples, includes all compounds which conform to the general formula CnH2n+1OH.
Di, You-Ying;Zhang, Guo-Chun;Liu, Yu-Pu;Kong, Yu-Xia;Zhou, Chun-Sheng research published 《 Crystal structure and thermodynamic properties of the coordination compound calcium D-gluconate Ca[D-C6H11O7]2(s)》, the research content is summarized as follows. The coordination compound calcium D-gluconate, Ca[D-C6H11O7]2(s), was synthesized and characterized by chem. anal., elemental anal., and x-ray crystallog. Single crystal x-ray diffraction technique revealed that the compound was formed by two D-gluconate anions and one calcium(II) cation. And the D-gluconate anion had a curved chain configuration with an intramol. bond. The compound exhibited an outstanding chelate property of D-gluconate anions to calcium(II) cations, and the calcium(II) cation was eight-coordinated and chelated by four D-gluconate anions. The lattice potential energy and ionic volume of the anion were calculated to be 1434.05 kJ·mol-1 and 0.4211 nm3 from crystallog. data. In accordance with famous Hess law, a reasonable thermochem. cycle was designed and the standard molar enthalpy of formation of Ca[D-C6H11O7]2(s) was calculated as ΔsHm[Ca[D-C6H11O7]2, s] = -(3545.19 ± 1.07) kJ·mol-1 by use of an isoperibol solution-reaction calorimeter. Furthermore, molar heat capacities of the compound were measured using a Quantum Design Phys. Properties Measurement System (PPMS) with sp. heat option within the temperature range from (1.9-300) K. The heat capacities of the compound increased with the temperature and no thermal anomaly was found in the whole temperature region. The exptl. data was fitted to a function of the absolute temperature T with a series of theor. and empirical models for the proper temperature ranges. The values of standard thermodn. function, Cop,m/J·K-1·mol-1, ΔT0Hom/kJ·mol-1, ΔT0Som/J·K-1·mol-1, and ΔToGom/T/J·K-1·mol-1 (=ΔT0Som-ΔT0Hom/T) from T = (0-300) K was calculated based on the fitting results. The standard molar heat capacity, entropy and enthalpy of the compound at T = 298.15 K and 0.1 MPa was determined to be Cop,m= (493.20 ± 2.70) J·K-1 mol-1, Hom= (75934 ± 805) J·mol-1, Som= (471.55 ± 2.78) J·K-1 mol-1, and Gom/T = – (64658 ± 808) J·K-1·mol-1, resp.
Synthetic Route of 527-07-1, Sodium Gluconate is the sodium salt of gluconic acid with chelating property. Sodium gluconate chelates and forms stable complexes with various ions, preventing them from engaging in chemical reactions.
Sodium gluconate is an organic sodium salt having D-gluconate as the counterion. It has a role as a chelator. It contains a D-gluconate.
D-Gluconic acid sodium salt is a glycol ether that is used as an injection solution. It has been shown to have antibacterial efficacy against wild-type strains of bacteria such as Escherichia coli, Pseudomonas aeruginosa, and Staphylococcus aureus. The in vitro antimicrobial action of D-gluconic acid sodium salt was found to be due to its ability to inhibit bacterial growth by interfering with the synthesis of DNA. D-gluconic acid sodium salt also has been shown to have antihypertensive effects in rats through the inhibition of angiotensin II type 1 receptor (AT1) signaling pathway and erythrocyte proliferation. This drug also has been shown to bind benzalkonium chloride and x-ray diffraction data show that it is crystalline in nature. The analytical method for determining the concentration of D-gluconic acid sodium salt is by electrochemical impedance, 527-07-1.
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts