Tag: M.W=200-250

Fischer, Christoph S. published the artcileEnhanced Brightness Emission-Tuned Nanoparticles from Heterodifunctional Polyfluorene Building Blocks, Product Details of C8H9BrO2, the main research area is enhanced brightness emission tuned nanoparticle heterodifunctional polyfluorene building block.

Three-coordinate complexes (bromo)[4-(2,2-dimethyl-1,3-dioxolan-4-yl)-phenyl](tri-tert-butyl-phosphine)palladium (1) and (bromo){4-[(tetrahydro-2H-pyran-2-yloxy)methyl]phenyl}(tri-tert-butyl-phosphine)palladium (2) were used to initiate Suzuki-Miyaura chain growth polymerization of 7′-bromo-9′,9′-dioctyl-fluoren-2′-yl-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane (3). The polymerization was optionally terminated by end-capping with red-emitting N-(2-ethylhexyl)-1,6-bis(4-tert-octylphenoxy)-9-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-perylene-3,4-dicarboximide. Heterodisubstituted polyfluorenes of adjustable mol. weights between 5 × 103 and 1.0 × 104 g mol-1 and narrow mol. weight distribution (Mw/Mn < 1.2), bearing precisely one or two hydroxyl groups on one chain end and optionally a dye-label on the opposite end, were obtained virtually devoid of any side-products. Covalent attachment of polyethylene glycol (Mn = 2 × 103 g mol-1) to the reactive end groups yielded amphiphilic block copolymer, which afforded stable nanoparticles with diameters in the range of 25-50 nm when dispersed in water. These particles exhibited a bright fluorescence emission with quantum yields as high as Φ = 84%, which could optionally be tuned to longer wavelengths by energy transfer to the perylene monoimide dye. The heterodifunctional nature of these polyfluorenes is crucial for a bright and enduring fluorescence brightness as revealed by comparison to nanoparticles containing phys. mixed dye. Further addition of terrylene diimide dye to the nanoparticles of perylene-end-capped polyfluorene block copolymers allows for an energy cascade resulting in emission exclusively in the deep red and near-IR regime. Journal of the American Chemical Society published new progress about Fluorescence. 92093-23-7 belongs to class alcohols-buliding-blocks, name is 1-(4-Bromophenyl)ethane-1,2-diol, and the molecular formula is C8H9BrO2, Product Details of C8H9BrO2.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Rouchaud, Anne published the artcileA new and efficient synthesis of derivatives of octahydro-4H-pyrrolo[1,2-c]pyrido[1′,2′-a]imidazole, Computed Properties of 87905-98-4, the main research area is octahydropyrrolopyridoimidazole preparation.

When di-Et malonate was added to a solution of Δ1-piperideine, generated in situ by oxidative desamination and decarboxylation of L-lysine by N-bromosuccinimide (NBS), formation of the unexpected tricyclic compound I was observed The structure of I was deduced from anal. of its spectroscopic data and was confirmed both by chem. degradation and by total synthesis. We proved that 3-bromo-1-piperideine was implicated in its formation. Moreover, based on this feature, a new and efficient synthesis of I was developed. The elaborated pathway was adapted to access derivatives related to I that differed in their C-4 substituent.

European Journal of Organic Chemistry published new progress about Michael reaction. 87905-98-4 belongs to class alcohols-buliding-blocks, name is Benzyl (5-hydroxypentyl)carbamate, and the molecular formula is C13H19NO3, Computed Properties of 87905-98-4.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Teodorovic, Aleksandar V. published the artcileStabilization of long-chain intermediates in solution. Tridecyl radicals and cations, Quality Control of 58783-82-7, the main research area is tetradecanoic acid decarboxylation product formation tridecyl radical rearrangement.

Tetradecanoic acid was decarboxylated by means of lead(IV) acetate (LTA) under thermal (81 °C) and photolytic (r.t.) conditions in benzene solution The mixture of products, obtained in thermal reaction, consists of esters (acetoxyalkanes and carboxylates), tridecenes, tridecane and phenyltridecane. Addnl., tetradecane and hexacosane, under photolytic conditions, were formed. The classes of products and their distribution might be explained by presence of intermediate 1-tridecyl radical which can undergo intramol. (result in formation of rearranged carbon centered radicals) and intermol. stabilization pathways. Exptl. obtained results were used as input data for computational Monte Carlo simulation study of the reaction. On the basis of these results, radical rearrangements, as well as hydride shifts in tridecyl system are discussed.

Journal of Molecular Structure published new progress about Deamination. 58783-82-7 belongs to class alcohols-buliding-blocks, name is 5-Tridecanol, and the molecular formula is C13H28O, Quality Control of 58783-82-7.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Wendeln, Christian published the artcileCarbohydrate Microarrays by Microcontact Printing, Synthetic Route of 87905-98-4, the main research area is carbohydrate microarray microcontact printing.

This Article describes the preparation of carbohydrate microarrays by the immobilization of carbohydrates via microcontact printing (μCP) on glass and silicon substrates. To this end, diene-modified carbohydrates (galactose, glucose, mannose, lactose, and maltose) were printed on maleimide-terminated self-assembled monolayers (SAMs). A Diels-Alder reaction occurred exclusively in the contact area between stamp and substrate and resulted in a carbohydrate pattern on the substrate. It was found that cyclopentadiene-functionalized carbohydrates could be printed within minutes at room temperature, whereas furan-functionalized carbohydrates required long printing times and high temperatures By successive printing, microstructured arrays of up to three different carbohydrates could be produced. Immobilization and patterning of the carbohydrates on the surfaces was investigated with contact angle measurements, XPS, time-of-flight secondary ion mass spectrometry (TOF-SIMS), and fluorescence microscopy. Furthermore, the lectins Con A (ConA) and peanut agglutinin (PNA) bind to the microarrays, and the printed carbohydrates retain their characteristic selectivity toward these proteins.

Langmuir published new progress about Carbohydrates Role: ARG (Analytical Reagent Use), BUU (Biological Use, Unclassified), PEP (Physical, Engineering or Chemical Process), RCT (Reactant), SPN (Synthetic Preparation), TEM (Technical or Engineered Material Use), ANST (Analytical Study), USES (Uses), BIOL (Biological Study), PROC (Process), RACT (Reactant or Reagent), PREP (Preparation) (diene-modified). 87905-98-4 belongs to class alcohols-buliding-blocks, name is Benzyl (5-hydroxypentyl)carbamate, and the molecular formula is C13H19NO3, Synthetic Route of 87905-98-4.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Hirose, Keiji published the artcileEnantioselective complexation of phenolic crown ethers with chiral aminoethanol derivatives: effects of substituents of aromatic rings of hosts and guests on complexation, Quality Control of 92093-23-7, the main research area is enantioselective complexation phenolic crown ether chiral aminoethanol substituent effect.

Optically active azophenolic crown ethers having Ph groups substituted at the resp. para-position were prepared and their association constants with chiral aminoethanol derivatives, including 2-amino-2-phenylethanols having an electron-donating or an electron-withdrawing group, were determined in chloroform by means of UV-vis titration methods. The enantioselectivities of these crown ethers are estimated from the ratio of the association constants KR/KS and the effect of aromatic substituents of both hosts and guests on the binding abilities and enantioselectivities is discussed. The structures of the complexes were investigated on the basis of the 1H NMR and UV-vis spectra.

Perkin 2 published new progress about Chiral recognition. 92093-23-7 belongs to class alcohols-buliding-blocks, name is 1-(4-Bromophenyl)ethane-1,2-diol, and the molecular formula is C8H9BrO2, Quality Control of 92093-23-7.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Connah, Liam published the artcileSynergy of Key Properties Promotes Dendrimer Conjugates as Prospective Ratiometric Bioresponsive Magnetic Resonance Imaging Probes, Formula: C13H19NO3, the main research area is polyamidoamine dendrimer MRI contrast agent calcium gadolinium.

Bioresponsive or smart contrast agents (SCAs) sensitive to Ca2+ are of extreme interest in the development of functional magnetic resonance imaging (MRI) techniques as they can aid in tracking neural activity in vivo. To this end, the design of macromol. systems based on nanoscaffolds such as dendrimers functionalized with multiple MRI contrast agents has been used to conveniently increase the local concentration of paramagnetic MR reporters and slow the diffusion time of the probe, which are favorable in vivo characteristics. Moreover, previous studies with Ca-sensitive dendrimeric MRI probes revealed favorable properties crucial in the development of a ratiometric T2/T1-imaging method that provided a higher contrast-to-noise ratio compared to conventional T1- or T2-weighted imaging protocols. We therefore developed a series of novel dendrimeric MRI probes (DCAs) with differing structural properties and charge distributions. We thoroughly studied their features such as the relaxometric behavior and size change and examined their electrostatic behaviors prior to and after the addition of Ca2+. The most active DCA displayed a common increase in r1 (3.11 to 5.72 mM-1 s-1) and a remarkable increase in r2 (7.44 to 34.57 mM-1 s-1), resulting in a r2/r1 ratio increase of the factor 2.52, which is greater than what was previously achieved. These changes in r1 and r2 were followed with a hydrodynamic diameter increase from 7.1 ± 1.2 to 8.5 ± 0.7 nm upon the addition of Ca2+, along with a decrease in the neg. surface charge of the nanoparticle. Overall, our findings indicate that highly responsive DCAs can be developed only through a combination of properties such as changes in hydration and size of the mol., which are a consequence of intramol. structural and electrostatic changes in the particle. In turn, they provide a model for future preparations of responsive DCAs that can be utilized for both T1-weighted and ratiometric T2/T1-weighted imaging to visualize essential biol. processes in a dynamic fashion.

Biomacromolecules published new progress about Hydration process. 87905-98-4 belongs to class alcohols-buliding-blocks, name is Benzyl (5-hydroxypentyl)carbamate, and the molecular formula is C13H19NO3, Formula: C13H19NO3.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Perez, Maria published the artcileSynthesis of novel glycoconjugates and evaluation as inhibitors against β-glucosidase from almond, SDS of cas: 2595-07-5, the main research area is hydrolase glucosidase inhibition glycoside glycoconjugate preparation disaccharide structure activity; amino glycoside disaccharide preparation glucosidase inhibitor glycoconjugate glucosaminide lactose.

Hydrolytic activity of glycosidases can be influenced by inhibitors of glycosidic nature. We have synthesized glycoconjugates consisting of galactose, glucosaminide or lactose 1-O-linked with allyl alc., pentenol or tetra-ethylene-glycol moieties. These compounds were found to be inhibitors of the hydrolase activity of the β-glucosidase from almond, with Ki in the range of 7.7-107 mM and presenting different types of inhibition. Based on the structure of the functionalized glycosides and the inhibition studies performed, we suggest that the nature of the carbohydrate is determinant in the inhibitory strength of these glycoconjugates.

Journal of Molecular Catalysis B: Enzymatic published new progress about Disaccharides Role: BSU (Biological Study, Unclassified), RCT (Reactant), SPN (Synthetic Preparation), BIOL (Biological Study), RACT (Reactant or Reagent), PREP (Preparation). 2595-07-5 belongs to class alcohols-buliding-blocks, name is (2R,3R,4S,5R,6R)-2-(Allyloxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol, and the molecular formula is C9H16O6, SDS of cas: 2595-07-5.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Di Brisco, Riccardo published the artcileDevelopment of a fluorescent probe for the study of the sponge-derived simplexide immunological properties, Application In Synthesis of 2595-07-5, the main research area is simplexide immunol fluorescent probe disaccharide glycoside preparation glycosylation pentatriacontanol.

Simplexide is a glycolipid of marine origin, endowed with immunol. properties, composed of a long chain secondary alc. glycosylated by an α-D-glucosyl-(1→4)-β-D-galactosyl disaccharide residue. Herein we describe the preparation of a fluorescent derivative of simplexide, labeled at position 6 of the distal glucose with a dansyl group, as a probe for future studies on the mechanism by which simplexide affects the immune system. Fluorescent simplexide was prepared from a 6”-amino functionalized compound, which in turn was obtained through a highly efficient glycosylation between the preformed activated disaccharide and the long chain secondary alc. 18-pentatriacontanol.

Carbohydrate Research published new progress about Fluorescent indicators. 2595-07-5 belongs to class alcohols-buliding-blocks, name is (2R,3R,4S,5R,6R)-2-(Allyloxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol, and the molecular formula is C9H16O6, Application In Synthesis of 2595-07-5.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Pawliczek, Martin published the artcileAlkylative kinetic resolution of vicinal diols under phase-transfer conditions: a chiral ammonium borinate catalysis, Quality Control of 92093-23-7, the main research area is alc benzyloxy allyloxy asym synthesis; vicinal diol enantioselective regioselective phase transfer alkylative kinetic resolution.

Enantioselective synthesis of alcs. I [R1 = Ph, 2-MeC6H4, cyclohexyl, etc.; R2 = Ph, 2-MeC6H4, 2-naphthyl, (E)-PhCH:CH, etc.] and II (R3 = Ph, 4-FC6H4, 3-thienyl, etc.; R4 = Me, CH2:CHCH2) via alkylative kinetic resolution of vicinal diols R1CH(OH)CH2OH or R3R4C(OH)CH2OH, resp., with allylic or benzylic bromides realized by cooperative use of a chiral quaternary ammonium salt and an achiral borinic acid is reported. In addition, a catalytic regioselective alkylation of a secondary alc. in the presence of an unprotected primary one was presented, emphasizing the unique selectivity and potential of this ammonium borinate catalysis.

Chemical Science published new progress about Alkylation catalysts, stereoselective. 92093-23-7 belongs to class alcohols-buliding-blocks, name is 1-(4-Bromophenyl)ethane-1,2-diol, and the molecular formula is C8H9BrO2, Quality Control of 92093-23-7.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Yang, Haimei published the artcileAn array consisting of glycosylated quantum dots conjugated to MoS2 nanosheets for fluorometric identification and quantitation of lectins and bacteria, Safety of (2R,3R,4S,5R,6R)-2-(Allyloxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol, the main research area is lectin glycosylated quantum dot molybdenum disulfide nanosheet fluorometry; Fluorescence; Linear discriminant analysis; Milk sample; Multiple analysis; Saccharide binding.

A fluorescent array based on the use of saccharide-functionalized multicolored quantum dots (s-QDs) and of 4-mercaptophenylboronic acid-functionalized MoS2 nanosheets (PBA-MoS2) was constructed for multiple identification and quantitation of lectins and bacteria. In this array, the fluorescence of the s-QDs is quenched by the PBA-MoS2 nanosheets. In the presence of multiple lectins, s-QDs differentially detach from the surface of PBA-MoS2 nanosheets, producing distinct fluorescence response patterns due to both quenching and enhancement of fluorescence. By analyzing the fluorescence responses with linear discriminant anal., multiple lectins and bacteria were accurately identified with 100% accuracy. The limits of detection of Con A, Pisum sativum agglutinin, Peanut agglutinin, and Ricius communis I agglutinin are as low as 3.7, 8.3, 4.2 and 3.9 nM, resp. The array has further been evidenced to be potent for distinguishing and quantifying different bacterial species by recognizing their surface lectins. The detection limits of Escherichia coli and Enterococcus faecium are 87 and 66 cfu mL-1, resp.

Microchimica Acta published new progress about Arachis hypogaea (agglutinin). 2595-07-5 belongs to class alcohols-buliding-blocks, name is (2R,3R,4S,5R,6R)-2-(Allyloxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol, and the molecular formula is C9H16O6, Safety of (2R,3R,4S,5R,6R)-2-(Allyloxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts