Tag: M.W=200-250

Niu, Tengfei published the artcileHeterogeneous carbon nitride photocatalyst for C-C bond oxidative cleavage of vicinal diols in aerobic micellar medium, SDS of cas: 92093-23-7, the main research area is aryl aldehyde preparation green chem; vicinal diol aerobic oxidation carbon nitride photocatalyst.

A green and efficient visible-light promoted aerobic oxidative C-C bond cleavage of vicinal diols RC(R1)(OH)C(R2)(OH)R3 (R = Ph, pyridin-2-yl, 4-bromophenyl, etc.; R1 = H, Me, Ph; R2 = H, Me, Ph; R3 = H, 4-nitrophenyl, Ph, furan-2-yl, etc.) in micellar medium has been developed. This protocol used graphitic carbon nitride with nitrogen vacancies (CN620) as a metal-free recyclable photocatalyst and CTAB as surfactant in water. Control experiments and the ESR results indicated that superoxide radicals and valence band holes played an important role in the reaction. Further isotope experiments suggested both a β-scission/HAT pathway and an oxidation/hydrolysis/dehydration pathway for the reaction, which is different from previous reports. The semiconductor/micellar catalyst system can be recycled at least 10 times without a significant reduction in activity. Furthermore, this reaction could be carried out under solar light irradiation and was applicable to large-scale reactions with similar results.

Green Chemistry published new progress about Aryl aldehydes Role: SPN (Synthetic Preparation), PREP (Preparation). 92093-23-7 belongs to class alcohols-buliding-blocks, name is 1-(4-Bromophenyl)ethane-1,2-diol, and the molecular formula is C8H9BrO2, SDS of cas: 92093-23-7.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Jones, Kevin M. published the artcileMetal-Free Dihydroxylation of Alkenes using Cyclobutane Malonoyl Peroxide, Formula: C8H9BrO2, the main research area is lactone preparation green chem; allylic alc preparation green chem; alkene dihydroxylation cyclobutane malonoyl peroxide.

Cyclobutane malonoyl peroxide I, prepared in a single step from the com. available diacid 6, is an effective reagent for the dihydroxylation of alkenes. Reaction of a chloroform solution of I with an alkene in the presence of 1 equiv of water at 40 °C followed by alk. hydrolysis leads to the corresponding diol, e.g., II, in 30-84% yield. With 1,2-disubstituted alkenes, the reaction proceeds with syn-selectivity (3:1 → 50:1). A mechanism consistent with exptl. findings is proposed, which is supported by deuterium and oxygen labeling studies and explains the stereoselectivity observed Alternative reaction pathways that are dependent on the structure of the starting alkene are also described leading to the synthesis of allylic alcs. and γ-lactones.

Journal of Organic Chemistry published new progress about Allylic alcohols Role: SPN (Synthetic Preparation), PREP (Preparation). 92093-23-7 belongs to class alcohols-buliding-blocks, name is 1-(4-Bromophenyl)ethane-1,2-diol, and the molecular formula is C8H9BrO2, Formula: C8H9BrO2.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Shen, Lingyun published the artcileSelective Transformation of Vicinal Glycols to α-Hydroxy Acetates in Water via a Dehydrogenation and Oxidization Relay Process by a Self-Supported Single-Site Iridium Catalyst, Application In Synthesis of 92093-23-7, the main research area is alpha hydroxy acetate preparation; vicinal glycol dehydrogenation oxidization relay process water; self supported single site iridium catalyst.

α-Hydroxy acids have attracted broad attention because of their prevalence in bioactive mols. and biodegradable polymers, but their conventional syntheses are usually restricted to aromatic substrates, especially, in a stepwise manner. Herein, the transformation of alkyl and aryl vicinal glycols to α-hydroxy acetates in water under the air atm. with the solid self-supported NHC-Ir single-site catalyst is reported. Both aliphatic and aromatic glycols are compatible with a much higher catalytic efficiency in the presence of this solid single-site catalyst than other viable mol. catalysts (93% vs <35%) because of the ""isolation effect"". Remarkably, this catalyst could be reused for 20 runs without an obvious loss in catalytic activity and selectivity. Control experiments and d. functional theory calculations reveal that the reaction firstly undergoes a dehydrogenation facilitated by the catalyst, and then it proceeds through an unexpected oxidization relay step by oxygen in the air, leading to the α-hydroxy acetate formation. This protocol can potentially contribute to the valorization of readily available and inexpensive diols. ACS Catalysis published new progress about Acetates Role: SPN (Synthetic Preparation), PREP (Preparation) (hydroxy). 92093-23-7 belongs to class alcohols-buliding-blocks, name is 1-(4-Bromophenyl)ethane-1,2-diol, and the molecular formula is C8H9BrO2, Application In Synthesis of 92093-23-7.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Pungente, Michael D. published the artcileAntibody-catalyzed formation of a 14-membered ring lactone, Formula: C13H19NO3, the main research area is macrocyclic phosphonate lactone preparation monoclonal antibody catalyst.

Monoclonal antibody (MAb) F123, raised against a macrocyclic phosphonate transition-state analog, catalyzed an intramol. transesterification of the corresponding hydroxy ester to give a 14-membered ring lactone. The MAB reaction displayed enzyme-like Michaelis-Menten kinetics with a Km of 255 μM and a kcat of 0.01 min-1 based on p-nitrophenol release and calculated on an active-site basis. Substrate specificity and competitive inhibition by a transition state analog (Ki = 3 μM) demonstrated that the catalytic activity was associated with binding in the antibody-combining site. The lactone product was isolated from a large-scale catalytic experiment through ether extraction and identified by gas chromatog. – mass spectroscopy.

Canadian Journal of Chemistry published new progress about Catalytic monoclonal antibodies Role: CAT (Catalyst Use), USES (Uses) (F123). 87905-98-4 belongs to class alcohols-buliding-blocks, name is Benzyl (5-hydroxypentyl)carbamate, and the molecular formula is C13H19NO3, Formula: C13H19NO3.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Xia, Chengfeng published the artcileThio-isoglobotrihexosylceramide, an Agonist for Activating Invariant Natural Killer T Cells, Formula: C9H16O6, the main research area is thioisoglobotrihexosylceramide natural killer T cell activation.

Thio-isoglobotrihexosylceramide (S-iGb3) might be resistant to α-galactosidases in antigen-presenting cells and have a longer retaining time in the lysosome before being loaded to CD1d. The biol. assay showed that S-iGb3 demonstrates a much higher increase as a stimulatory ligand toward invariant natural killer T (iNKT) cells as compared to iGb3.

Organic Letters published new progress about CD1d antigens Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 2595-07-5 belongs to class alcohols-buliding-blocks, name is (2R,3R,4S,5R,6R)-2-(Allyloxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol, and the molecular formula is C9H16O6, Formula: C9H16O6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Abe, Shigeaki published the artcileVersatile synthesis of oligosaccharide-containing fullerenes, Application In Synthesis of 87905-98-4, the main research area is oligosaccharide fullerene preparation; oxylamine fullerene preparation; ligation oxylamine fullerene oligosaccharide.

Oxylamine-functionalized fullerene derivatives have been synthesized in order to attach oligosaccharides to the fullerene surface by simple chem. ligation. This method greatly simplifies the synthetic process for a variety of oligosaccharide-containing fullerenes without any complicated chem. modification.

Tetrahedron: Asymmetry published new progress about Fullerenes Role: SPN (Synthetic Preparation), PREP (Preparation) (oligosaccharide). 87905-98-4 belongs to class alcohols-buliding-blocks, name is Benzyl (5-hydroxypentyl)carbamate, and the molecular formula is C13H19NO3, Application In Synthesis of 87905-98-4.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Tanimoto, Toshiko published the artcileRetention behavior of positional isomers of disubstituted cyclomalto-oligosaccharide (cyclodextrin) derivatives on an ODS column, Formula: C13H28O, the main research area is disubstituted cyclomalto oligosaccharide retention liquid chromatog; HPLC disubstituted cyclomalto oligosaccharide ODS column; cyclodextrin derivative positional isomer ODS column liquid chromatog.

The correlation between hydrophobic effects and structures of three and four positional isomers of 61,6n-di-O-triphenylmethyl (trityl)- or 61,6n-di-O-tert.- butyldimethylsilyl (tert.-BuMe2Si)-cyclomaltohexaoses (cG6s, α-cyclodextrin) (n = 2-4), -cyclomaltoheptaoses (cG7s, β-cyclodextrin) (n = 2-4), and -cyclomaltooctaoses (cG8s, γ-cyclodextrin) (n = 2-5) on an ODS column are discussed. Cyclodextrins with two hydrophobic-substituted groups bonded to hydroxyl groups tended to show low retention of positional isomers in which the binding positions of the two substituted groups on the cyclodextrin ring were far apart from each other.

Journal of Chromatography A published new progress about Aliphatic alcohols Role: ANT (Analyte), PRP (Properties), ANST (Analytical Study). 58783-82-7 belongs to class alcohols-buliding-blocks, name is 5-Tridecanol, and the molecular formula is C13H28O, Formula: C13H28O.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Chung, Jou-Ku published the artcileStructure-toxicity relationship study of para-halogenated styrene analogues in CYP2E1 transgenic cells, Formula: C8H9BrO2, the main research area is structure toxicity relationship styrene analog bioactivation CYP2E1.

Styrene is one of the most important industrial intermediates consumed in the world and is mainly used as a monomer for reinforced plastics and rubber. Styrene has been found to be hepatotoxic and pneumotoxic in humans and exptl. animals. The toxicity of styrene is suggested to be metabolism-dependent. Styrene-7,8-oxide has been considered as the major metabolite responsible for styrene-induced cytotoxicity. The objective of the study was to investigate the correlation between cytotoxicity of styrene and chem. and biochem. properties of the vinyl group of styrene by development of structure activity relationships (SAR). 4-Fluorostyrene, 4-chlorostyrene and 4-bromostyrene were selected for the SAR study. Cytotoxicity of styrene and the halogenated styrene derivatives with an order of 4-bromostyrene > 4-chlorostyrene > 4-fluorostyrene ≈ styrene was observed in CYP2E1 transgenic cells. Similar orders in the efficiency of the metabolism of styrene and the halogenated styrene analogs to their oxides and in the electrophilicity of the corresponding oxides were observed Addnl., the order of the potency of cellular glutathione depletion and the degree of protein adduction induced by styrene and the halogenated styrenes were consistent with that of their cytotoxicities. The wild-type cells were less susceptible to the toxicity of the corresponding model compounds than CYP2E1 cells. The present study provided insight into the roles of the biochem. and chem. properties of styrene in its cytotoxicity.

Toxicology Letters published new progress about Cytotoxicity. 92093-23-7 belongs to class alcohols-buliding-blocks, name is 1-(4-Bromophenyl)ethane-1,2-diol, and the molecular formula is C8H9BrO2, Formula: C8H9BrO2.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Wang, Yan-Bing published the artcileNaOH-Mediated Direct Synthesis of Quinoxalines from o-Nitroanilines and Alcohols via a Hydrogen-Transfer Strategy, Recommanded Product: 1-(4-Bromophenyl)ethane-1,2-diol, the main research area is sodium hydroxide quinoxaline synthesis nitroaniline alc hydrogen transfer.

A NaOH-mediated sustainable synthesis of functionalized quinoxalines is disclosed via redox condensation of o-nitroamines with diols and α-hydroxy ketones. Under optimized conditions, various o-nitroamines and alcs. are well tolerated to generate the desired products in 44-99% yields without transition metals and external redox additives.

Journal of Organic Chemistry published new progress about Cyclocondensation reaction (redox cyclocondensation). 92093-23-7 belongs to class alcohols-buliding-blocks, name is 1-(4-Bromophenyl)ethane-1,2-diol, and the molecular formula is C8H9BrO2, Recommanded Product: 1-(4-Bromophenyl)ethane-1,2-diol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Gao, Yongjun published the artcileEfficient Preparation of Glycoclusters from Silsesquioxanes, COA of Formula: C13H19NO3, the main research area is POSS polyhedral oligosilsesquioxane preparation photochem addition human glycoprotein receptor; human glycoprotein inhibition receptor glycocluster silsesquioxane preparation addition lectin; glycocluster silsesquioxane preparation lactoside mannoside photochem addition glycoside oligosaccharide.

A new type of glycocluster based on polyhedral oligo-silsesquioxanes (POSS) has been efficiently prepared from unprotected mannoside and lactoside employing a convergent approach of thiol-radical addition reaction. The versatility of this approach was demonstrated by functionalization of mannosides and lactosides of different-length spacers. Preliminary lectin binding study indicated that these novel glycoclusters showed strong inhibition of the binding of asialo-oligosaccharide mixture derived from human 1-acid glycoprotein by RCA120.

Organic Letters published new progress about Glycoproteins Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 87905-98-4 belongs to class alcohols-buliding-blocks, name is Benzyl (5-hydroxypentyl)carbamate, and the molecular formula is C13H19NO3, COA of Formula: C13H19NO3.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts