Tag: M.W=200-250

Lee, Reiko T. published the artcileSynthesis of 3-(2-aminoethylthio)propyl glycosides, HPLC of Formula: 2595-07-5, the main research area is allyl alc glycoside addition; ethylthiopropyl glycoside; glucopyranoside ethylthiopropyl; galactopyranoside ethylthiopropyl.

Anomeric pairs of 3-(2-aminoethylthio)propyl D-galactopyranoside D-glucopyranoside and 2-acetamido-2-deoxy-D-glucopyranoside were prepared by addition of H2N(CH2)2SH to the corresponding anomeric allyl glycosides. The allyl α-glycosides were prepared by refluxing the sugars with allyl alc. in the presence of an acid catalyst; the allyl β-glycosides were prepared by the reaction of acetylated glycosyl bromides with allyl alc. in the presence of Hg(CN)2 followed by O-deacetylation. The rate of thiol addition to the allylic group was different for each glycoside.

Carbohydrate Research published new progress about Glycosides Role: SPN (Synthetic Preparation), PREP (Preparation). 2595-07-5 belongs to class alcohols-buliding-blocks, name is (2R,3R,4S,5R,6R)-2-(Allyloxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol, and the molecular formula is C9H16O6, HPLC of Formula: 2595-07-5.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Ziegler, Thomas published the artcileSynthesis of the 5-aminopentyl glycoside of β-D-Galp-(1→4)-β-D-GlcpNAc-(1→3)-L-Fucp and fragments thereof related to glycopeptides of human Christmas factor and the marine sponge Microciona prolifera, Synthetic Route of 87905-98-4, the main research area is aminopentyl glycoside acetamidodeoxy oligosaccharide; glycopeptide christmas factor acetamidodeoxy oligosaccharide; marine sponge Microciona prolifera oligosaccharide.

The marine sponge Microciona prolifera and human coagulation factor IX (Christmas factor)-related mono- to tri-saccharide 5-aminopentyl glycosides β-D-Galp-R, β-D-GlcpNAc-R (16), β-D-Galp-(1→4)-β-D-GlcpNAc-R, β-D-GlcpNAc-(1→3)-β-L-Fucp-R, β-D-GlcpNAc-(1→3)-α-L-Fucp-R, β-D-Galp-(1→4)-β-D-GlcpNAc-(1→3)- β-L-Fucp-R, and β-D-Galp-(1→4)-β-D-GlcpNAc-(1→3)- α-L-Fucp-R, where R is a 5-aminopentyloxy spacer moiety, which allowed the construction of glycoconjugates, were prepared

Carbohydrate Research published new progress about Glycosides Role: SPN (Synthetic Preparation), PREP (Preparation). 87905-98-4 belongs to class alcohols-buliding-blocks, name is Benzyl (5-hydroxypentyl)carbamate, and the molecular formula is C13H19NO3, Synthetic Route of 87905-98-4.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Nilsson, Kurt G. I. published the artcileA simple strategy for changing the regioselectivity of glycosidase-catalyzed formation of disaccharides. Part II. Enzymic synthesis in situ of various acceptor glycosides, Application In Synthesis of 2595-07-5, the main research area is galactopyranoside acceptor preparation; transglycosidation lactose galactosidase; raffinose transglycosidation; galactopyranosylgalactopyranoside disaccharide.

β-D-Galactosidase induced the formation of allyl, benzyl, and trimethylsilylethyl β-D-galactopyranosides on a 1-20 g scale from lactose and allyl alc., benzyl alc., and trimethylsilylethanol. Similarly, α-D-galactosidase catalyzed the formation of allyl α-D-galactopyranoside from raffinose and allyl alc. The galactosides were used as acceptors for the preparation of several galactopyranosylgalactopyranoside disaccharides.

Carbohydrate Research published new progress about Glycosides Role: SPN (Synthetic Preparation), PREP (Preparation). 2595-07-5 belongs to class alcohols-buliding-blocks, name is (2R,3R,4S,5R,6R)-2-(Allyloxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol, and the molecular formula is C9H16O6, Application In Synthesis of 2595-07-5.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Wang, Azhong published the artcilePalladium-Catalyzed Direct Oxidation of Alkenes with Molecular Oxygen: General and Practical Methods for the Preparation of 1,2-Diols, Aldehydes, and Ketones, Related Products of alcohols-buliding-blocks, the main research area is terminal disubstituted olefin oxygen base palladium dihydroxylation; diol preparation; oxygen terminal disubstituted olefin PTSA palladium oxidative cleavage; aldehyde Ketone preparation green chem reaction mechanism; dihydroxylation oxidative cleavage catalyst palladium.

Novel and environmentally benign methods for palladium-catalyzed dihydroxylation and oxidative cleavage of olefins with oxygen as sole oxidant are presented. The cleavage reactions were performed with acid as additive in aqueous solution, whereas 1,2-diols were formed in the presence of base. A broad substrate scope has been demonstrated allowing monosubstituted aromatic and aliphatic terminal alkenes, 1,2-disubstituted, and 1,1-disubstituted olefins. The cleavage reactions of dioxo-PdII complexes implicate 1,2-diol might act as a key intermediate of olefin cleavage.

Journal of Organic Chemistry published new progress about Aldehydes Role: SPN (Synthetic Preparation), PREP (Preparation). 92093-23-7 belongs to class alcohols-buliding-blocks, name is 1-(4-Bromophenyl)ethane-1,2-diol, and the molecular formula is C8H9BrO2, Related Products of alcohols-buliding-blocks.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Meng, Shan-Shui published the artcileAerobic oxidation of alcohols with air catalyzed by decacarbonyldimanganese, Application of 1-(4-Bromophenyl)ethane-1,2-diol, the main research area is manganese catalyzed aerobic oxidation functionalized alc.

The oxidation of alcs. to carbonyl compounds using air as the terminal oxidant is highly desirable. As described in previous reports, the abstraction of α-H of the alc. is the most important step, and it typically requires not only a metal catalyst but also complex ligands, co-catalysts and bases. Herein, we report a practical and efficient method for the oxidation of primary alcs., secondary alcs., 1,2-diols, 1,2-amino alcs., and other α-functionalized alcs. using a com. available catalyst, Mn2(CO)10, and no additives. Preliminary mechanistic studies indicated that an alkoxyl radical intermediate existed in our system, and a plausible mechanism consistent with the exptl. results and literature was proposed.

Green Chemistry published new progress about Amino alcohols Role: RCT (Reactant), RACT (Reactant or Reagent). 92093-23-7 belongs to class alcohols-buliding-blocks, name is 1-(4-Bromophenyl)ethane-1,2-diol, and the molecular formula is C8H9BrO2, Application of 1-(4-Bromophenyl)ethane-1,2-diol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Xie, Ya-Fei published the artcileBifunctional organocatalysts for the conversion of CO2, epoxides and aryl amines to 3-aryl-2-oxazolidinones, Related Products of alcohols-buliding-blocks, the main research area is aryl oxazolidinone preparation; epoxide carbon dioxide aryl amine regioselective ring opening cycloaddition.

A route to synthesize 3-aryl-2-oxazolidinones I (R1 = Me, H2C:CHCH2OCH2, Ph, 4-FC6H4, etc.; R2 = Ph, 1-naphthyl, 2-pyridyl, etc.) through a three-component reaction between CO2, aryl amines R2NH2, and the corresponding 2-R1-substituted epoxides with a binary organocatalytic system composed of organocatalysts II (R3 = R4 = Me; R3 = H, R4 = Me, i-Pr, MeSCH2, Ph, 4-HOC6H4; X = I, Br, Cl) and DBU (1,8-diazabicyclo[5.4.0]undec-7-ene) was developed. The method allows wide scopes of epoxide and aryl amine substrates with various functional groups under mild reaction conditions. The control experiments indicate that a cyclic carbonate is formed via cycloaddition of epoxides with CO2, which further reacts with the β-amino alc. originating from epoxides and aryl amines, resulting in the formation of 3-aryl-2-oxazolidinones.

Organic & Biomolecular Chemistry published new progress about Aromatic amines Role: RCT (Reactant), RACT (Reactant or Reagent). 92093-23-7 belongs to class alcohols-buliding-blocks, name is 1-(4-Bromophenyl)ethane-1,2-diol, and the molecular formula is C8H9BrO2, Related Products of alcohols-buliding-blocks.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Russo, Laura published the artcileThiol-ene Mediated Neoglycosylation of Collagen Patches: A Preliminary Study, COA of Formula: C9H16O6, the main research area is thiol ene neoglycosylation collagen patch surface treatment.

Despite the relevance of carbohydrates as cues in eliciting specific biol. responses, the covalent surface modification of collagen-based matrixes with small carbohydrate epitopes has been scarcely investigated. We report thereby the development of an efficient procedure for the chemoselective neoglycosylation of collagen matrixes (patches) via a thiol-ene approach, between alkene-derived monosaccharides and the thiol-functionalized material surface. Synchrotron radiation-induced XPS (SR-XPS), Fourier transform-IR (FT-IR), and enzyme-linked lectin assay (ELLA) confirmed the effectiveness of the collagen neoglycosylation. Preliminary biol. evaluation in osteoarthritic models is reported. The proposed methodol. can be extended to any thiolated surface for the development of smart biomaterials for innovative approaches in regenerative medicine.

Langmuir published new progress about Collagen type I Role: RCT (Reactant), RACT (Reactant or Reagent). 2595-07-5 belongs to class alcohols-buliding-blocks, name is (2R,3R,4S,5R,6R)-2-(Allyloxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol, and the molecular formula is C9H16O6, COA of Formula: C9H16O6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Holme, Kevin R. published the artcileN-[2-(Glycosyloxy)ethyl]chitosan derivatives. Part I. Preparation and characterization of N-[2-(glycosyloxy)ethyl]chitosan derivatives., Name: (2R,3R,4S,5R,6R)-2-(Allyloxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol, the main research area is chitosan glycosyloxyethyl preparation water solubility; glycosyloxyethylchitosan preparation water solubility; allyl glycoside preparation carbon proton NMR; ozonolysis allyl glycoside; reduction alkylation chitosan oxoethyl formylmethyl glycoside.

Allyl glycosides of 8 simple sugars were prepared and characterized, including 1H- and 13C-NMR assignments. Formylmethyl glycosides, obtained by reductive ozonolysis of the allyl glycosides, were reductively N-alkylated to chitosan with typical yields of 80%. The glycosides of α- and β-D-glucopyranose, α- and β-D-galactopyranose, 2-acetamido-2-deoxy-α- and β-D-glucopyranose, β-D-glucuronic acid, and β-lactose were incorporated by this method. The degree of substitution (d.s.) of the products was controlled by varying the molar ratio of glycoside to free amine groups of chitosan by between 0.5 and 3.0. Derivatives of degree of substitution > 0.3 were typically water soluble, and compounds of higher d.s. generally gave less-viscous aqueous solutions Assignment of 13C-NMR chem. shifts verified the structure of these derivatives The linewidths of the branch resonances (5-100 Hz) provided qual. information about the relationship between d.s. and branch mobility. The resonances of high-d.s. products were narrower and more intense than analogous low-d.s. derivatives The chitosan resonances of the backbone were generally broader (50-200 Hz) and less intense, and as a result were difficult to assign fully.

Carbohydrate Research published new progress about Carbohydrates Role: SPN (Synthetic Preparation), PREP (Preparation). 2595-07-5 belongs to class alcohols-buliding-blocks, name is (2R,3R,4S,5R,6R)-2-(Allyloxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol, and the molecular formula is C9H16O6, Name: (2R,3R,4S,5R,6R)-2-(Allyloxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Farkas, Erzsebet published the artcileEnzymatic synthesis of galactose-containing disaccharides employing β-galactosidase from Bacillus circulans, COA of Formula: C9H16O6, the main research area is galactose disaccharide enzymic preparation; carbohydrate enzymic galactosylation.

Galβ1â†? disaccharide structures are vital core units of the oligosaccharide components of glycoconjugates. β-Galactosidase from Bacillus circulans (E.C.3.2.1.23) catalyzes the transfer of galactose from a donor structure such as GalβOpNP to various GlcNAc and galactose derivatives, forming β1â†? linkages. The synthesis of several biol. relevant disaccharides [Galβ1â†?GlcNAcαOAll, Galβ1â†?GlcNAcβOAll, Galβ1â†?GalαOAll, Galβ1â†?GalβOAll, Galβ1â†?GalβSPh, Galβ1â†?GalβOpNP] and the trisaccharide Galβ1â†?Galβ1â†?GalβOpNP was achieved in 30-66% yield by application of this enzyme.

European Journal of Organic Chemistry published new progress about Disaccharides Role: SPN (Synthetic Preparation), PREP (Preparation). 2595-07-5 belongs to class alcohols-buliding-blocks, name is (2R,3R,4S,5R,6R)-2-(Allyloxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol, and the molecular formula is C9H16O6, COA of Formula: C9H16O6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Fukuhara, Kenji published the artcileRegioselective, Tin-Free Sulfation of Unprotected Hexopyranosides by Using Phenylboronic Acid, Related Products of alcohols-buliding-blocks, the main research area is regioselective sulfation unprotected glycopyranoside phenylboronic acid hydroxy group protecting; trichloroethyl protected glycoside preparation; unprotected glycopyranoside regioselective sulfation trichloroethyl sulfurylimidazolium.

Regioselective, tin-free sulfation of a number of unprotected glycopyranosides derived from L-fucose, L-rhamnose, D-arabinose, D-glucose, D-galactose, and D-trehalose was achieved by using phenylboronic acid for masking the hydroxy groups and a 2,2,2-trichloroethyl-protected sulfurylimidazolium salt as the sulfating reagent. The formation of phenylborate ester remarkably improved the solubility of the carbohydrates in organic solvents and indicated high reactivity and regioselectivity in the sulfation reactions. This methodol. was successfully adapted to result in a one-pot procedure that did not require separation or purification of the reaction intermediates.

European Journal of Organic Chemistry published new progress about Arylboronic acids Role: RCT (Reactant), RACT (Reactant or Reagent). 2595-07-5 belongs to class alcohols-buliding-blocks, name is (2R,3R,4S,5R,6R)-2-(Allyloxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol, and the molecular formula is C9H16O6, Related Products of alcohols-buliding-blocks.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts