Tag: M.W=200-250

Timmer, Brian J. J. published the artcileAcid-Assisted Direct Olefin Metathesis of Unprotected Carbohydrates in Water, Product Details of C9H16O6, the main research area is disaccharide glycoside chelation galactopyranoside mannoside preparation olefin metathesis minimization; carbene ligands; carbohydrates; homogeneous catalysis; olefin metathesis; synthetic methods.

The ability to use unprotected carbohydrates in olefin metathesis reactions in aqueous media is demonstrated. By using water-soluble, amine-functionalized Hoveyda-Grubbs catalysts under mildly acidic aqueous conditions, the self-metathesis of unprotected alkene-functionalized α-D-manno- and α-D-galactopyranosides could be achieved through minimization of non-productive chelation and isomerization. Cross-metathesis with allyl alc. could also be achieved with reasonable selectivity. The presence of small quantities (2.5 vol %) of acetic acid increased the formation of the self-metathesis product while significantly reducing the alkene isomerization process. These results demonstrate the potential of directly using unprotected carbohydrate structures in olefin metathesis reactions under mild conditions compatible with biol. systems, and thereby enabling their use in, for example, drug discovery and protein derivatization.

Chemistry – A European Journal published new progress about Chelation. 2595-07-5 belongs to class alcohols-buliding-blocks, name is (2R,3R,4S,5R,6R)-2-(Allyloxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol, and the molecular formula is C9H16O6, Product Details of C9H16O6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Kachholz, T. published the artcileDegradation of long chain alkanes by bacilli. II. Metabolic pathways, Synthetic Route of 58783-82-7, the main research area is Bacillus alkane metabolism temperature.

Five species of bacilli tested at 30° degraded hydrocarbons by cooxidn. A subterminal degradation pathway in these bacilli was proved by the presence of isomeric esters (like the products of Baeyer-Villiger oxidation of ketones), diols, ketols, and diketones. The composition of fatty acids in the lipids of bacilli grown with and without alkane and with position of fatty acids in the lipids of bacilli grown with and without alkane and with labeled n-tridecane suggested a subterminal, partly di-subterminal, pathway. Bacillus stearothermophilus did not grow on alkane as the sole C source even in a thermophilic temperature range; oxidation products were formed in amounts 20-fold less when grown on cooxidn. medium at 50°, compared to product formation on the same medium at 30°.

European Journal of Applied Microbiology and Biotechnology published new progress about Diketones. 58783-82-7 belongs to class alcohols-buliding-blocks, name is 5-Tridecanol, and the molecular formula is C13H28O, Synthetic Route of 58783-82-7.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Prathima, P. Sai published the artcileCuI/L-proline-catalyzed selective one-step mono-acylation of styrenes and stilbenes, Quality Control of 92093-23-7, the main research area is monoacylated diol preparation copper proline catalyst; styrene stilbene vicinal dioxygenation copper proline catalyst.

Vicinal di-oxygenation of styrene-type olefins was achieved with cheaper, less toxic CuI in the presence of L-proline as ligand and NaIO4 as the oxidant. This approach provides a straightforward and efficient access to mono-acylated diols from both styrene and stilbene derivatives with good to excellent yields and diastereoselectivity.

Tetrahedron Letters published new progress about Acylation. 92093-23-7 belongs to class alcohols-buliding-blocks, name is 1-(4-Bromophenyl)ethane-1,2-diol, and the molecular formula is C8H9BrO2, Quality Control of 92093-23-7.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Cai, Zhongyu published the artcileResponsive Photonic Crystal Carbohydrate Hydrogel Sensor Materials for Selective and Sensitive Lectin Protein Detection, HPLC of Formula: 2595-07-5, the main research area is photonic crystal carbohydrate hydrogel sensor detection lectin; biosensors; carbohydrate hydrogels; copolymerization; lectin proteins detection; photonic crystals.

Lectin proteins, such as the highly toxic lectin protein, ricin, and the immunochem. important lectin, jacalin, play significant roles in many biol. functions. It is highly desirable to develop a simple but efficient method to selectively detect lectin proteins. Here the authors report the development of carbohydrate containing responsive hydrogel sensing materials for the selective detection of lectin proteins. The copolymerization of a vinyl linked carbohydrate monomer with acrylamide and acrylic acid forms a carbohydrate hydrogel that shows specific “”multivalent”” binding to lectin proteins. The resulting carbohydrate hydrogels are attached to 2-D photonic crystals (PCs) that brightly diffract visible light. This diffraction provides an optical readout that sensitively monitors the hydrogel volume The authors use lactose, galactose, and mannose containing hydrogels to fabricate a series of 2-D PC sensors that show strong selective binding to the lectin proteins ricin, jacalin, and Con A. This binding causes a carbohydrate hydrogel shrinkage which significantly shifts the diffraction wavelength. The resulting 2-D PC sensors can selectively detect the lectin proteins ricin, jacalin, and Con A. These unoptimized 2-D PC hydrogel sensors show a limit of detection (LoD) of 7.5 × 10-8 M for ricin, a LoD of 2.3 × 10-7 M for jacalin, and a LoD of 3.8 × 10-8 M for Con A, resp. This sensor fabrication approach may enable numerous sensors for the selective detection of numerous lectin proteins.

ACS Sensors published new progress about Biosensors. 2595-07-5 belongs to class alcohols-buliding-blocks, name is (2R,3R,4S,5R,6R)-2-(Allyloxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol, and the molecular formula is C9H16O6, HPLC of Formula: 2595-07-5.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Balcerzak, Anna K. published the artcileStructurally diverse disaccharide analogs of antifreeze glycoproteins and their ability to inhibit ice recrystallization, Quality Control of 2595-07-5, the main research area is structure activity antifreeze glycoprotein inhibit ice recrystallization disaccharide preparation; galactosamine disaccharide preparation antifreeze glycoprotein inhibit ice recrystallization.

The β-D-galactosyl-(1,3)-α-N-acetyl-D-galactosamine disaccharide is present in antifreeze glycoproteins (AFGPs). Analogs of this disaccharide including the β-linked (1,3)-, (1,4)-, and (1,6)-galactosyl-N-acetyl galactosamine and the β-(1,3)-galactosyl-galactoside were synthesized and evaluated for ice recrystallization inhibition (IRI) activity. The results from this study demonstrate that the β-linked-(1,4) disaccharide exhibits more potent IRI activity than the native β-linked-(1,3) disaccharide. The C2 N-acetyl group of the disaccharide does not affect IRI activity but in monosaccharides, the presence of the C2 N-acetyl group decreases IRI activity. The current study will facilitate the design of potent small-mol. ice recrystallization inhibitors.

Bioorganic & Medicinal Chemistry Letters published new progress about Antifreeze. 2595-07-5 belongs to class alcohols-buliding-blocks, name is (2R,3R,4S,5R,6R)-2-(Allyloxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol, and the molecular formula is C9H16O6, Quality Control of 2595-07-5.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Houseman, Benjamin T. published the artcileCarbohydrate arrays for the evaluation of protein binding and enzymatic modification, COA of Formula: C13H19NO3, the main research area is carbohydrate array protein binding.

This paper reports a chem. strategy for preparing carbohydrate arrays and utilizes these arrays for the characterization of carbohydrate-protein interactions. Carbohydrate chips were prepared by the Diels-Alder-mediated immobilization of carbohydrate-cyclopentadiene conjugates to self-assembled monolayers that present benzoquinone and penta(ethylene glycol) groups. Surface plasmon resonance spectroscopy showed that lectins bound specifically to immobilized carbohydrates and that the glycol groups prevented nonspecific protein adsorption. Carbohydrate arrays presenting ten monosaccharides were then evaluated by profiling the binding specificities of several lectins. These arrays were also used to determine the inhibitory concentrations of soluble carbohydrates for lectins and to characterize the substrate specificity of β-1,4-galactosyltransferase. Finally, a strategy for preparing arrays with carbohydrates generated on solid phase is shown. This surface engineering strategy will permit the preparation and evaluation of carbohydrate arrays that present diverse and complex structures.

Chemistry & Biology published new progress about Adsorption. 87905-98-4 belongs to class alcohols-buliding-blocks, name is Benzyl (5-hydroxypentyl)carbamate, and the molecular formula is C13H19NO3, COA of Formula: C13H19NO3.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Kachholz, T. published the artcileDegradation of long chain alkanes by bacillus. I. Development and product formation by bacilli degrading alkanes in the presence of other carbon sources, SDS of cas: 58783-82-7, the main research area is Bacillus alkane oxidation; alc formation Bacillus alkane.

No Bacillus among 14 type strains and 100 soil isolates could assimilate C14-C18 alkanes as sole C source, although 5 type strains could oxidize alkanes in the presence of glucose. When grown with pure n-C13H28, or n-C14H30, the 5 strains gave mainly mixtures of the corresponding secondary alcs., with some ketone and small amounts of primary alcs. B. lentus oxidized C13H28 poorly compared to C14H30. B. stearothermophilus and B. macerans gave �0-fold more alcs. than the other species. The extracellular fatty acid composition of B. macerans changed when alkane was added to a glucose-based medium.

European Journal of Applied Microbiology published new progress about Fatty acids. 58783-82-7 belongs to class alcohols-buliding-blocks, name is 5-Tridecanol, and the molecular formula is C13H28O, SDS of cas: 58783-82-7.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Blute, Irena published the artcilePhase behavior of alkyl glycerol ether surfactants, Category: alcohols-buliding-blocks, the publication is Tenside, Surfactants, Detergents (1998), 35(3), 207-212, database is CAplus.

The phase behavior and phys. properties of a series of alkyl (C₆, C₈, C₁₂ and iso-C₈) monoglycerol ethers and 2-hydroxyalkyl (C₆, C₈, C₁₂) monoglycerol ethers are presented. The binary phase diagram for the surfactants shows very little dependence on temperature It can be seen that as the alkyl chain length increases the tendency to form lamellar liquid crystalline phases increases. The branched alkyl chain shows no formation of lamellar phases even at high concentrations of surfactant. The difference in phase behavior between the surfactants is attributed to the variation in the critical packing parameter of the surfactants. The presence of an addnl. hydroxyl group in the alkyl chain causes temperature-independent solubility behavior. Ternary phase diagrams were prepared using dodecane as the oil phase. Hexyl glycerol ether was the only one of the alkyl glycerol ethers that was sufficiently water-soluble to determine the surface tension and CMC. The CMC was 15 mM and surface tension was 26 mN m^-1.

Tenside, Surfactants, Detergents published new progress about 70445-33-9. 70445-33-9 belongs to alcohols-buliding-blocks, auxiliary class Aliphatic Chain, name is 3-((2-Ethylhexyl)oxy)propane-1,2-diol, and the molecular formula is C11H24O3, Category: alcohols-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Shinoda, Kozo published the artcilePrinciples of attaining very large solubilization (microemulsion): inclusive understanding of the solubilization of oil and water in aqueous and hydrocarbon media, Recommanded Product: 3-((2-Ethylhexyl)oxy)propane-1,2-diol, the publication is Journal of Physical Chemistry (1984), 88(21), 5126-9, database is CAplus.

It is intrinsically important to change the hydrophile-lipophile balance (HLB) of surfactant mixture continuously by various devices in order to attain a large solubilization or ultimately complete mixing of hydrocarbon and H₂O with less surfactant. The maximum solubilization of hydrocarbon (or H₂O) was observed close to the surfactant phase separation at which the hydrophile-lipophile property of a surfactant mixture balances for a given system. The relative solubilities of H₂O and oil in the surfactant phase change with the HLB of a surfactant mixture When the hydrophile-lipophile property of a surfactant is balanced, 3 phases, i.e., H₂O, surfactant, and oil, coexist at low surfactant concentration When it is hydrophilic the solubility of water in the surfactant phase is infinite and an aqueous solubilized micellar solution + oil system is obtained. When it is lipophilic the solubility of oil in the surfactant phase is infinite and a reversed micellar solution of hydrocarbon + water system is obtained. These conceptual interpretations on the solubilization of oil and water in surfactant aggregates were embodied on the phase diagrams presented. The devices of cosurfactants, surfactants, and their combinations yielded very large solubilization. The hydrophile-lipophile balance (HLB) of a surfactant is certainly a functions of various variables such as surfactant composition, temperature, valence of the counterions, salt concentration, etc. It is argued that the HLB of a surfactant in the system and the HLB number of the surfactant should not be confused.

Journal of Physical Chemistry published new progress about 70445-33-9. 70445-33-9 belongs to alcohols-buliding-blocks, auxiliary class Aliphatic Chain, name is 3-((2-Ethylhexyl)oxy)propane-1,2-diol, and the molecular formula is C7H16ClNO2, Recommanded Product: 3-((2-Ethylhexyl)oxy)propane-1,2-diol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Ryzhkov, O. G. published the artcileInterrelation of the structure and properties of mono- and dialkylpyrocatechols, Related Products of alcohols-buliding-blocks, the publication is Khimiya Tverdogo Topliva (Leningrad) (1975), 154-9, database is CAplus.

Alkylation of pyrocatechol, by olefins (e.g., propene trimer and diisobutylene) and alcs. (e.g., Me2CHCH2OH, Me2CHCH2CH2OH), catalyzed by cationite KU 2, gave 3- and 4-monoalkyl and 3,5-dialkyl derivatives; product compositions were determined by uv, ir, and thin-layer chromatog. Ionization constants of the monoalkyl derivatives were determined

Khimiya Tverdogo Topliva (Leningrad) published new progress about 1139-46-4. 1139-46-4 belongs to alcohols-buliding-blocks, auxiliary class Benzene,Phenol, name is 4-(2,4,4-Trimethylpentan-2-yl)benzene-1,2-diol, and the molecular formula is C14H22O2, Related Products of alcohols-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts