Tag: M.W=150-200

Zhang, Kaifu published the artcileSynthesis of a Gold-Metal Oxide Core-Satellite Nanostructure for In Situ SERS Study of CuO-Catalyzed Photooxidation, Product Details of C9H22OSi, the publication is Angewandte Chemie, International Edition (2020), 59(41), 18003-18009, database is CAplus and MEDLINE.

This work reports on an assembling-calcining method for preparing gold-metal oxide core-satellite nanostructures, which enable surface-enhanced Raman spectroscopic detection of chem. reactions on metal oxide nanoparticles. By using the nanostructure, we study the photooxidation of Si-H catalyzed by CuO nanoparticles. As evidenced by the in situ spectroscopic results, oxygen vacancies of CuO are found to be very active sites for oxygen activation, and hydroxyl radicals (·OH) adsorbed at the catalytic sites are likely to be the reactive intermediates that trigger the conversion from silanes into the corresponding silanols. According to our finding, oxygen vacancy-rich CuO catalysts are confirmed to be of both high activity and selectivity in photooxidation of various silanes.

Angewandte Chemie, International Edition published new progress about 17877-23-5. 17877-23-5 belongs to alcohols-buliding-blocks, auxiliary class Protection and Derivatization Reagent, name is Triisopropylsilanol, and the molecular formula is C21H24O8, Product Details of C9H22OSi.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Zhang, Zhihao published the artcileSerum metabolomics reveals the effect of electroacupuncture on urinary leakage in women with stress urinary incontinence, Synthetic Route of 621-37-4, the publication is Journal of Pharmaceutical and Biomedical Analysis (2020), 113513, database is CAplus and MEDLINE.

Stress urinary incontinence (SUI), which is defined as an involuntary loss of urine upon phys. exertion coughing, sneezing or laughing, has a significant neg. impact on the quality of life of many women. Multi-center, large-scale and randomized clin. trials have illustrated that non-invasive electroacupuncture is an effective treatment for SUI, but its therapeutic mechanism in treating SUI remains unknown. Here, gas chromatog.-mass spectrometry based serum metabolomics was performed to reveal metabolic profiles and diagnostic biomarkers from recruitment of 25 patients and 25 healthy women before and after electroacupuncture. We identified 10 differentially abundant metabolites, including butantriol, 3,4-dihydroxybutanoic acid, succinic acid, 1-deoxypentitol, psicose, citric acid, 3-hydroxybutyric acid, hydracrylic acid, 3-hydroxyphenylacetic acid and D-mannitol, from patients between before and after electroacupuncture. The electroacupuncture therapy altered propanoate metabolism, butanoate metabolism and the tricarboxylic acid cycle. A panel of 8 biomarkers (butantriol, 3,4-dihydroxybutanoic acid, succinic acid, 1-deoxypentitol, psicose, citric acid, 3-hydroxybutyric acid and hydracrylic acid) was evaluated to determine the effect of electroacupuncture on SUI and differentiated well between before and after treatment. The area under the receiver operating characteristic curve was 0.962. The sensitivity, specificity and coincidence rate were 92%, 92% and 96%, resp., at a 95% confidence interval ranging from 0.9053 to 1. Furthermore, the levels of these diagnostic biomarkers were not significantly altered in healthy subjects after sham electroacupuncture. It was indicated that an 8-biomarker panel might be constructed for the therapeutic evaluation of electroacupuncture treatment for SUI.

Journal of Pharmaceutical and Biomedical Analysis published new progress about 621-37-4. 621-37-4 belongs to alcohols-buliding-blocks, auxiliary class Carboxylic acid,Benzene,Phenol,Natural product, name is 3-Hydroxyphenylacetic acid, and the molecular formula is C4H12ClNO, Synthetic Route of 621-37-4.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Liao, Liangkun published the artcileAnti-inflammatory effect of essential oil from Amomum Tsaoko Crevost et Lemarie, Quality Control of 106-25-2, the publication is Journal of Functional Foods (2022), 105087, database is CAplus.

Amomum Tsaoko Crevost et Lemarie is a kind of spices and traditional Chinese medicines with great com. value. Traditional treatment often uses essential oils from Amomum Tsaoko in aromatherapy. In this study, researchers analyzed the composition of steam-distilled essential oil from Amomum tsaoko (ATEO) and evaluated its potential antioxidant and anti-inflammatory activity. GC-MS identified a total of 33 volatile compounds, the majority of which were alc. (1,8-cineole and nerol) and aldehyde ((2E)-2-decenal) compounds Addnl., ATEO showed great anti-inflammatory activity in LPS-induced RAW 264.7 macrophages. ATEO markedly inhibited the nitric oxide (NO) release, and decreased the expression level of TNF-α, IL-1β, IL-6 and monocyte chemotactic protein-1 (MCP-1) in a dose-dependent manner. Furthermore, ATEO significantly reduced the expression of iNOS, COX-2, NF-κB p-p65 and p-ERK. These results suggested that ATEO has great anti-inflammatory activity in LPS-induced RAW 264.7 cells, which will facilitate the development of ATEO as a functional food.

Journal of Functional Foods published new progress about 106-25-2. 106-25-2 belongs to alcohols-buliding-blocks, auxiliary class Natural product, name is cis-3,7-Dimethyl-2,6-Octadien-1-Ol, and the molecular formula is C10H18O, Quality Control of 106-25-2.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Mandlaa published the artcileL-sorbose is not only a substrate for 2-keto-L-gulonic acid production in the artificial microbial ecosystem of two strains mixed fermentation, Name: (3S,4R,5S)-3,4,5,6-Tetrahydroxy-2-oxohexanoic acid, the publication is Journal of Industrial Microbiology & Biotechnology (2015), 42(6), 897-904, database is CAplus and MEDLINE.

The co-culture system of the fermentation process of vitamin C can be regarded as an artificial microbial ecosystem (AME). To extend our understanding of this AME, an investigation of the relationship between strains, substrate and product was carried out in this study. The results showed that both Ketogulonicigenium vulgare and 2-keto-L-gulonic acid (2-KLG, the precursor of vitamin C) can inhibit the growth of the helper strain, while the helper strain promoted the growth of K. vulgare and 2-KLG production Moreover, L-sorbose is not only a substrate for 2-KLG production in the AME, but also a promoter of K. vulgare and an inhibitor of the helper strain. In the earlier stage of fermentation, the inhibition of L-sorbose on the helper strain’s growth is a key factor for ensuring an efficient fermentation In the condition of adding the extra helper strain (OD: 0.57, ratio of inoculation: 2 %), the yields of 2-KLG is increased by 9 % in the 14 % L-sorbose medium. To the best of our knowledge, this is the first report about the inhibition of substrate in the AME of 2-KLG production

Journal of Industrial Microbiology & Biotechnology published new progress about 526-98-7. 526-98-7 belongs to alcohols-buliding-blocks, auxiliary class Sugar Units,Other Sugar Units, name is (3S,4R,5S)-3,4,5,6-Tetrahydroxy-2-oxohexanoic acid, and the molecular formula is C6H10O7, Name: (3S,4R,5S)-3,4,5,6-Tetrahydroxy-2-oxohexanoic acid.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Mandlaa published the artcileTwo-helper-strain co-culture system: a novel method for enhancement of 2-keto-L-gulonic acid production, COA of Formula: C6H10O7, the publication is Biotechnology Letters (2013), 35(11), 1853-1857, database is CAplus and MEDLINE.

A novel two-helper-strain co-culture system (TSCS) was developed to enhance 2-keto-L-gulonic acid (2-KLG) productivity for vitamin C production Bacillus megaterium and B. cereus (with a seeding culture ratio of 1:3, volume/volume), used as helper strains, increased the 2-KLG yield using Ketogulonigenium vulgare compared to the conventional one-helper-strain (either B. cereus or B. megaterium) co-culture system (OSCS). After 45 h cultivation, 2-KLG concentration in the TSCS (69 g l^-1) increased by 8.9 and 7 % over that of the OSCS (B. cereus: 63.4 g l^-1; B. megaterium: 64.5 g l^-1). The fermentation period of TSCS was 4 h shorter than that of OSCS (B. cereus). The increased cell numbers of K. vulgare stimulated by the two helper strains possibly explain the enhanced 2-KLG yield. The results imply that TSCS is a viable method for enhancing industrial production of 2-KLG.

Biotechnology Letters published new progress about 526-98-7. 526-98-7 belongs to alcohols-buliding-blocks, auxiliary class Sugar Units,Other Sugar Units, name is (3S,4R,5S)-3,4,5,6-Tetrahydroxy-2-oxohexanoic acid, and the molecular formula is C6H10O7, COA of Formula: C6H10O7.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Zhu, X. published the artcileInfluence of Saccharomyces cerevisiae autochthonous MQ3 strain on terpenes during the alcoholic fermentation of Chardonnay dry white wine, COA of Formula: C10H18O, the publication is Australian Journal of Grape and Wine Research (2022), 28(1), 41-49, database is CAplus.

Terpenes are major varietal aroma compounds significantly contributing to wine quality and style. Autochthonous microbial starters can promote the formation and release of the terpenes and thus highlight the terroir typicality of wines. This study compared the physicochem. parameters, changes in the terpene concentration, β-D-glucosidase activity and sensory attributes of Chardonnay wines fermented individually by the Saccharomyces cerevisiae autochthonous MQ3 strain isolated from spontaneous fermented grape must and by three com. S. cerevisiae strains. The evolution of terpenes during alc. fermentation was followed with ultrasound-assisted liquid-liquid extraction combined with GC. The physicochem. parameters of wine fermented by the MQ3 strain were significantly different from those of the wines fermented by other yeasts. The pattern of the terpenes detected, including linalool, α-terpineol, farnesol, geraniol, nerol and citronellol, varied during alc. fermentation The MQ3 strain induced greater accumulation of terpenes with increased concentration of α-terpineol, geraniol and (E,E)-farnesol. Besides, the MQ3 strain exhibited an enhanced ability to produce β-D-glucosidase compared to that of the other three strains. With the exception of α-terpineol and (E,E)-farnesol, there was no significant correlation between the concentration of the other terpenoids and β-D-glucosidase activity as shown by Pearson’s correlation anal. Wine produced with the MQ3 strain was characterised by a distinctive complex flavor with enhanced floral and fruity aromas. Conclusions : The autochthonous MQ3 strain had a pos. effect on the varietal aroma and sensory quality of the wines. Significance of the Study : Due to its aroma enhancing ability, the MQ3 strain could be applied to produce quality Chardonnay wine with terroir typicality.

Australian Journal of Grape and Wine Research published new progress about 106-25-2. 106-25-2 belongs to alcohols-buliding-blocks, auxiliary class Natural product, name is cis-3,7-Dimethyl-2,6-Octadien-1-Ol, and the molecular formula is C15H20BNO3, COA of Formula: C10H18O.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Cao, Jilei published the artcileMetal-free hydrogen evolution cross-coupling enabled by synergistic photoredox and polarity reversal catalysis, HPLC of Formula: 17877-23-5, the publication is Green Chemistry (2021), 23(22), 8988-8994, database is CAplus.

A synergistic combination of photoredox and polarity reversal catalysis enabled a hydrogen evolution cross-coupling of silanes with H₂O, alcs., phenols, and silanols, which afforded the corresponding silanols, monosilyl ethers, and disilyl ethers, resp., in moderate to excellent yields. The dehydrogenative cross-coupling of Si-H and O-H proceeded smoothly with broad substrate scope and good functional group compatibility in the presence of only an organophotocatalyst 4-CzIPN and a thiol HAT catalyst, without the requirement of any metals, external oxidants and proton reductants, which is distinct from the previously reported photocatalytic hydrogen evolution cross-coupling reactions where a proton reduction cocatalyst such as a cobalt complex is generally required. Mechanistically, a silyl cation intermediate is generated to facilitate the cross-coupling reaction, which therefore represents an unprecedented approach for the generation of silyl cation via visible-light photoredox catalysis.

Green Chemistry published new progress about 17877-23-5. 17877-23-5 belongs to alcohols-buliding-blocks, auxiliary class Protection and Derivatization Reagent, name is Triisopropylsilanol, and the molecular formula is C9H22OSi, HPLC of Formula: 17877-23-5.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Wang, Xuewei published the artcileYnamide-Mediated Intermolecular Esterification, Recommanded Product: 4-(1H-Pyrrol-1-yl)phenol, the publication is Journal of Organic Chemistry (2020), 85(9), 6188-6194, database is CAplus and MEDLINE.

An ynamide-mediated one-pot, two-step intermol. esterification via the condensation of carboxylic acids with nucleophilic hydroxyl species is reported. A broad substrate scope with respect to carboxylic acids, alcs., and phenols is observed The α-acyloxyenamide intermediates formed by the addition of carboxylic acids to ynamides proved to be effective acylating reagents for the esterification of alc. and phenol derivatives with the assistance of base catalysis. Notably, the racemization of the α-chiral center of carboxylic acids can be avoided.

Journal of Organic Chemistry published new progress about 23351-09-9. 23351-09-9 belongs to alcohols-buliding-blocks, auxiliary class Pyrrole,Benzene,Alcohol, name is 4-(1H-Pyrrol-1-yl)phenol, and the molecular formula is C18H35NO, Recommanded Product: 4-(1H-Pyrrol-1-yl)phenol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Wang, Hou published the artcileEnantioseparation of amino acid and mandelic acid enantiomers using Garphos derivatives as chiral extractants, Application of 2-Hydroxy-2-phenylacetic acid, the publication is Chirality (2022), 34(9), 1239-1246, database is CAplus and MEDLINE.

In this paper, Garphos with different substituents were employed as chiral extractants to enantiosep. racemic amino acid and mandelic acid. The influences of metal precursors, pH of aqueous solution, Garphos-metal concentration, extraction temperature, and substituent effect on extraction were investigated. The results indicated that the substituent groups significantly affected the π-π interaction between extractant and substrate. And the separation factors (α) for Garphos could be remarkably improved by regulating substituent groups. Garphos-II-Pd, Garphos-VI-Pd, Garphos-III-Pd, Garphos-I-Cu, Garphos-VI-Cu, and Garphos-V-Pd were the most efficient extractants for phenylalanine (Phe), homophenylalanine (Hphe), 4-nitrophenylalanine (Nphe), 3-chlorophenylglycine (Cpheg), mandelic acid (MA), and 2-chlormandelic acid (CMA) with α values of 2.40, 2.37, 5.37, 1.59, 5.98, and 3.69, resp. This work provided an important reference for the design of efficient chiral extractants in future work.

Chirality published new progress about 90-64-2. 90-64-2 belongs to alcohols-buliding-blocks, auxiliary class Carboxylic acid,Benzene,Alcohol,Natural product, name is 2-Hydroxy-2-phenylacetic acid, and the molecular formula is C21H20BrNO4S, Application of 2-Hydroxy-2-phenylacetic acid.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Chen, Jiayu published the artcileCharacterization of the key differential volatile components in different grades of Dianhong Congou tea infusions by the combination of sensory evaluation, comprehensive two-dimensional gas chromatography-time-of-flight mass spectrometry, and odor activity value, Synthetic Route of 106-25-2, the publication is LWT–Food Science and Technology (2022), 113755, database is CAplus.

Aroma is an important factor in evaluating tea infusion quality. In this study, the aroma quality of 44 Dianhong Congou tea infusions was classified into high-quality group and non-high-quality group according to the sensory evaluation. The volatile components were investigated by using headspace solid phase microextraction combined with comprehensive two-dimensional gas chromatog.-time-of-flight mass spectrometry. A total of 258 volatile components were identified, of which the three component types with the highest relative percentages were alcs. (17.05%), aldehydes (15.12%), and heterocycles (15.12%). Clear discrimination was achieved by orthogonal partial least squares discrimination anal. (R2Y = 0.94, Q2 = 0.82). In addition, 69 important differential compounds were identified based on variable importance in the projection value (VIP > 1.0) and one-way ANOVA (p < 0.05). Moreover, seven common key odorants with odor activity values (OAVs) >1 were screened out, including (E, E)-2,4-heptadienal, linalool, 1-octene-3-one, geraniol, β-myrcene, (Z)-4-heptenal, and nonanal. Aroma character impact value indicated that linalool performed a pos. supportive role in the aroma quality of Dianhong Congou tea infusions, while (E, E)-2,4-heptadienal neg. affected the aroma quality. These results contribute to providing a theor. support for directional processing of high-quality black tea.

LWT–Food Science and Technology published new progress about 106-25-2. 106-25-2 belongs to alcohols-buliding-blocks, auxiliary class Natural product, name is cis-3,7-Dimethyl-2,6-Octadien-1-Ol, and the molecular formula is C10H18O, Synthetic Route of 106-25-2.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts