Tag: M.W=150-200

Zhang, Yanrong published the artcileA further understanding on the strength development of cement pastes in the presence of triisopropanolamine used in CRTS III slab track, Synthetic Route of 122-20-3, the publication is Construction and Building Materials (2022), 125743, database is CAplus.

Accelerators are commonly used in the self-compacting concrete of CRTS III slab track to advance its strength development in cold areas. Triisopropanolamine (TIPA) is a known accelerator, and its influences on the strength development of hardened cement pastes (HCPs) were discussed based on a further understanding of cement hydration and microstructure. The results show that the addition of TIPA visibly heightens hydration degree at each age because it triggers the reaction of C4AF and gently promotes C3S hydration. At low dosages, more hydrates deposited in capillary pores facilitate a refined pore structure and therefore, significantly increase the early and late strengths. On the contrary, a high dosage of TIPA results in a loose and porous structure at an early age owing to the emergence of numerous AFm platelets and the reduction of Ca(OH)₂ crystals, so that the heightened hydration degree only slightly increases the early compressive and flexural strengths. At a later age, high dosages of TIPA cause an increase in the volume of harmful pores (greater than 50 nm), which may result from the appearance of some pores full of fractional AFm and the changed morphol. of Ca(OH)₂. Therefore, the late compressive strength of HCPs remains almost unchanged under the pos. effect of the heightened hydration degree coupled with the neg. effect of the increased volume of the harmful pores. In contrast, the late flexural strength sharply decreases, which is ascribed to both of the increased volume of the pores larger than 50 nm and the morphol. changes of hydration products.

Construction and Building Materials published new progress about 122-20-3. 122-20-3 belongs to alcohols-buliding-blocks, auxiliary class Organic Pigment, name is Triisopropanolamine, and the molecular formula is C24H20Ge, Synthetic Route of 122-20-3.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Zhang, Pianpian published the artcileMass production of a single-atom cobalt photocatalyst for high-performance visible-light photocatalytic CO₂ reduction, Formula: C9H21NO3, the publication is Journal of Materials Chemistry A: Materials for Energy and Sustainability (2021), 9(46), 26286-26297, database is CAplus.

The photocatalytic reduction of carbon dioxide (CO₂RR) into value-added chem. products is a promising way to enrich energy supply and reduce CO₂ emission. The proposal of a high-efficiency, low-cost and easy-to-operate photocatalyst is an essential segment for promoting the CO₂RR from small-scale laboratory examination to large-scale industrial application. Herein, we first come up with a Co photocatalyst with isolated Co single atoms anchored on a com. super conductive carbon black (Co-SA@SP-800) and employ it to effectively boost the photocatalytic CO₂ reduction reaction. Large scale production of the Co-SA@SP-800 catalyst can be achieved by a simple and practical adsorption-pyrolysis method. The as-prepared Co-SA@SP-800 catalyst presents remarkable photoactivity and CO selectivity with a CO production yield of 1.64 x 104μmol g^-1 and a CO selectivity of 84.2% after 2 h of UV illumination in a heterogeneous system, and significantly outperforms other reference samples and most of the other efficient photocatalysts reported recently toward the conversion of CO₂. In situ diffuse reflectance IR Fourier transform (DRIFT) spectroscopy was carried out to investigate the reaction intermediates during the photocatalytic CO₂RR. Control experiments and theor. calculations revealed that the isolated single at. Co-N₄ sites greatly lower the energy barrier for the desorption of CO* during CO₂-to-CO conversion, while suppressing H₂ evolution in the competing water splitting reaction. This work provides valuable new insights for rationally designing and synthesizing high-performance single atom catalysts for photocatalytic CO₂ reduction with ease of large-scale production

Journal of Materials Chemistry A: Materials for Energy and Sustainability published new progress about 122-20-3. 122-20-3 belongs to alcohols-buliding-blocks, auxiliary class Organic Pigment, name is Triisopropanolamine, and the molecular formula is C5H6N2O2, Formula: C9H21NO3.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Zhang, H.-L. published the artcileEnantioselective synthesis of enantiopure chiral alcohols using carbonyl reductases screened from Yarrowia lipolytica, Recommanded Product: 7-Chloro-2,3,4,5-tetrahydro-1H-benzo[b]azepin-5-ol, the publication is Journal of Applied Microbiology (2019), 126(1), 127-137, database is CAplus and MEDLINE.

Aims : We aimed to explore Yarrowia lipolytica carbonyl reductases as effective biocatalysts and to develop efficient asym. reduction systems for chiral alc. synthesis. Methods and Results : Yarrowia lipolytica carbonyl reductase genes were obtained via homologous sequence amplification strategy. Two carbonyl reductases, YaCRI and YaCRII, were identified and characterized, and used to catalyze the conversion of 2-hydroxyacetophenone (2-HAP) to optically pure (S)-1-phenyl-1,2-ethanediol. Enzymic assays revealed that YaCRI and YaCRII exhibited specific activities of 6·96 U mg^-1 (99·8% e.e.) and 7·85 U mg^-1 (99·9% e.e.), resp., and showed moderate heat resistance at 40-50°C and acid tolerance at pH 5·0-6·0. An efficient whole-cell two-phase system was established using reductase-expressing recombinant Escherichia coli. The conversion of 2-HAP (20·0 g l^-1) conversion with the solvent of di-Bu phthalate was approx. 70-fold higher than in water. Furthermore, the two recombinant E. coli displayed biocatalyst activity and enantioselectivity towards several different carbonyl compounds, and E. coliBL21 (DE3)/pET-28a-yacrII showed a broad substrate spectrum. Conclusions : A new whole-cell recombinant E. coli-based bioreduction system for enantiopure alc. synthesis with high enantioselectivity at high substrate concentrations was developed. Significance and Impact of the Study : We proposed a promising approach for the efficient preparation of enantiopure chiral alcs.

Journal of Applied Microbiology published new progress about 1310357-40-4. 1310357-40-4 belongs to alcohols-buliding-blocks, auxiliary class Benzenes, name is 7-Chloro-2,3,4,5-tetrahydro-1H-benzo[b]azepin-5-ol, and the molecular formula is C24H12, Recommanded Product: 7-Chloro-2,3,4,5-tetrahydro-1H-benzo[b]azepin-5-ol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Wang, Ting published the artcileThe underlying rationality of Chinese medicine herb pair Coptis chinensis and Dolomiaea souliei: From the perspective of metabolomics and intestinal function, COA of Formula: C8H8O3, the publication is Journal of Ethnopharmacology (2022), 115065, database is CAplus and MEDLINE.

The combination of Coptis chinensis (RC) and Dolomiaea souliei (VR) has long been used as a classic herb pair for the treatment of gastrointestinal diseases, but the underlying mechanisms remain unknown. In this study, the rationality of evidence-based RC and VR combination was explored from the perspective of metabolism, gut microbiota and gastrointestinal function. After 5 wk treatment, VR extracts (700 mg/kg) and RC alkaloids (800 mg/kg) showed no toxic effect on mice. However, RC administration significantly decreased the body weight of mice. Gastric emptying, gastrointestinal motility function and the absorption of FITC dextran were retarded in the mice of RC group, taking RC along with low dose VR (RC-VRL) and high dose VR (RC-VRH) reversed the impaired gastrointestinal function caused by RC. RC administration significantly increased villus height/crypt depth value. Notably, VR administration increased the number of crypts in mice ileum and reduced villus height/crypt depth value in VR and RC combination group. RC treatment significantly increased the expression of occludin compared to NC group; RC-VRL treatment reversed this tendency. While, VR administration increased ZO1 expression by 99.4% compared to NC mice. As for gut microbiota, RC gavage decreased the gut microbiota diversity, but gut microbiota in VR group was similar to NC group, and VR and RC combination increased gut microbiota diversity. RC administration obviously increased the proportion of Akkermansia muciniphila, Bacteroides thetaiotaomicron, Parabacteroides distasonis, and Escherichia coli, compared to NC mice. VR treatment increased the richness of Bacteroides thetaiotaomicron, Parabacteroides distasonis. RC-VRL and RC-VRH treatment dose-dependently increased the richness of Rikenellaceae RC9, Lactobacillus, and decreased the abundance of Psychrobacter, Bacteroides and Ruminococcus in mice. Serum metabolomic anal. revealed that RC gavage significantly down regulated 76 metabolites and up regulated 31 metabolites. VR treatment significantly down regulated 30 metabolites and up regulated 12 metabolites. Weight loss caused by RC may attribute to the elevated methylxanthine level in mice. The potential adverse effects caused by high dose RC intake may partially alleviate by high serum contents of adenosine, inosine and urolithin A resulted from VR coadministration. VR may alleviate RC caused “fluid retention” via normalizing gastrointestinal function, gut microbiota and modulating the perturbed metabolism

Journal of Ethnopharmacology published new progress about 90-64-2. 90-64-2 belongs to alcohols-buliding-blocks, auxiliary class Carboxylic acid,Benzene,Alcohol,Natural product, name is 2-Hydroxy-2-phenylacetic acid, and the molecular formula is C8H4FNO3, COA of Formula: C8H8O3.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Li, Shuhong published the artcileStudy on changes of volatile components in instant scallop before and after sterilization, Category: alcohols-buliding-blocks, the publication is Shipin Gongye Keji (2012), 33(4), 117-121, database is CAplus.

The influence of sterilization on flavor components in instant scallop was investigated. Gas chromatog.-mass spectrometry (GC-MS) combined with technique of headspace solid phase micro-extraction (HS-SPME) was used to analyze flavor components in instant scallop before and after sterilization. The results showed that 117 flavor components in scallop before sterilization and 119 ones in scallop after sterilization, resp. In the instant scallop before sterilization, the content of alcs., aldehydes, esters, ketones, acids, aromatic series, furans, phenols, hydrocarbon and others content was 3.21%, 4.78%, 2.06%, 0.47%, 0.25%, 8.38%, 0.03%, 0.72%, 32.58% and 47.52%, the number was 7, 9, 9, 4, 2, 22, 1, 1, 33 and 29, resp. In the instant scallop after sterilization, the content of alcs., aldehydes, esters, ketones, acids, aromatic series, furans, phenols, hydrocarbon and others content was 2.85%, 4.48%, 11.54%, 0.90%, 0.49%, 7.81%, 0.86%, 0.55%, 28.20% and 42.32%, the number was 9, 11, 11, 6, 5, 15, 5, 3, 32 and 22, resp., 67 ingredients species were the same in before and after sterilization scallop. The contents of aroma components of instant scallops after sterilization esters and furans were significantly more than that before sterilization. Thus sterilization process on the aroma components of instant scallop had a role in the retention and aroma, making instant scallop seafood was more dense fragrance, aroma coordination.

Shipin Gongye Keji published new progress about 23351-09-9. 23351-09-9 belongs to alcohols-buliding-blocks, auxiliary class Pyrrole,Benzene,Alcohol, name is 4-(1H-Pyrrol-1-yl)phenol, and the molecular formula is C10H9NO, Category: alcohols-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Chen, Kai published the artcileFreeze-thaw cycles characterize varietal aroma of Vidal blanc grape during late harvest by shaping self-assembled microeukaryotic communities, Application of cis-3,7-Dimethyl-2,6-Octadien-1-Ol, the publication is Food Chemistry (2022), 132553, database is CAplus and MEDLINE.

To study the effects of microeukaryotic communities on development of varietal aroma of Vidal blanc grape during late harvest, metagenomics, gas chromatog.-mass spectrometry, climate factors and SEM were jointly used to discover how freeze-thaw stress influences grape skin and shapes the microeukaryotic consortia. Most free terpenes, monoterpenes and C13-norisoprenoids developed during late harvest. Freeze-thaw cycles caused damage of the wax layer and microfissures on the cuticle of grape berries. This increased nutrients availability and supported the dominance of oxidative and fermentative ascomycetous populations. Microbial assemblages possessed certain ecosystem functions, which correlated to the development of characteristic volatile organic compounds, such as free terpenes and phenylalanine derivatives Significantly upregulated genes of CAZy were identified as FENNEDOB12352, OJNJMGIN252777, EGHMEMAM161340, EGHMEMAM158447, KKFIDJDF144524, BEDCFLNK31943, LHALBBHN88115, BEDCFLNK41042. Zymoseptoria tritici, Kluyveromyces lactis, Yarrowia lipolytica, and Pichia kudriavzevii were selected as key factors in yeast assemblage.

Food Chemistry published new progress about 106-25-2. 106-25-2 belongs to alcohols-buliding-blocks, auxiliary class Natural product, name is cis-3,7-Dimethyl-2,6-Octadien-1-Ol, and the molecular formula is C10H18O, Application of cis-3,7-Dimethyl-2,6-Octadien-1-Ol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Cai, Lei published the artcileGenetic engineering of Ketogulonigenium vulgare for enhanced production of 2-keto-L-gulonic acid, HPLC of Formula: 526-98-7, the publication is Journal of Biotechnology (2012), 157(2), 320-325, database is CAplus and MEDLINE.

Folate derivatives are crucial growth factors for Ketogulonigenium vulgare which is used in mixed culture with Bacillus megaterium for the industrial production of 2-keto-L-gulonic acid (2-KGA), the precursor of L-ascorbic acid (L-AA) or vitamin C (Vc). To improve the growth and 2-KGA production, five genes involved in folate biosynthesis identified in a folate gene cluster from Lactococcus lactis MG1363, including folB, folKE, folP, folQ and folC, were over-expressed in K. vulgare. Intracellular folate concentration in the recombinant strain harboring folate biosynthesis genes cluster under the control of P_sdh (sorbose dehydrogenase gene sdh promoter from K. vulgare) was 8 times higher than that of the wildtype K. vulgare DSM 4025 (P < 0.001). In shake flask studies, the cell d. and 2-KGA production of the recombinant K. vulgare Rif (pMCS2PsdhfolBC) were increased by 18% (P < 0.001) and 14% (P < 0.001), resp., under a relatively stable pH 7 condition. In fermentor studies, enhancements around 25% cell d. (P < 0.001) and approx. 35% 2-KGA productivity (P < 0.001) were observed in comparison with the controls without over-expressing the folate biosynthesis genes. This was the first successful study of metabolic engineering on K. vulgare for enhanced 2-KGA production

Journal of Biotechnology published new progress about 526-98-7. 526-98-7 belongs to alcohols-buliding-blocks, auxiliary class Sugar Units,Other Sugar Units, name is (3S,4R,5S)-3,4,5,6-Tetrahydroxy-2-oxohexanoic acid, and the molecular formula is C6H10O7, HPLC of Formula: 526-98-7.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Gao, Yun published the artcileComprehensive Quality Evaluation of Corn Steep Liquor in 2-Keto-L-gulonic Acid Fermentation, Category: alcohols-buliding-blocks, the publication is Journal of Agricultural and Food Chemistry (2011), 59(18), 9845-9853, database is CAplus and MEDLINE.

Corn steep liquor (CSL) is one of the main raw materials in 2-keto-L-gulonic acid (2-KLG) fermentation by Ketogulonicigenium vulgare and Bacillus megaterium. Due to its natural origin and variations in the manufacturing process, unpredicted and uncontrolled variability of CSL has a great influence on 2-KLG production; however, conventional quality specifications are not enough to ensure stability of fermentation behaviors. A process anal. technol. (PAT) could be considered to explore the relationship between CSL quality and 2-KLG production comprehensively. The compositions of CSL from six manufacturers were profiled by gas chromatog. with time-of-flight mass spectrometry (GC-TOFMS) and inductively coupled plasma-at. emission spectroscopy (ICP-AES), combined with orthogonal partial least-squares discriminant anal. (OPLS-DA). Seventeen components were identified as the most discriminant marker compounds related to 2-KLG production Results revealed that they were responsible for providing nutrients and protecting osmotic pressure. Furthermore, nine amino acids were verified as potential group markers by addition to the medium and demonstration of the correlation to 2-KLG production The comprehensive approach provided an important platform to explore CSL marker compounds for quality evaluation in 2-KLG fermentation

Journal of Agricultural and Food Chemistry published new progress about 526-98-7. 526-98-7 belongs to alcohols-buliding-blocks, auxiliary class Sugar Units,Other Sugar Units, name is (3S,4R,5S)-3,4,5,6-Tetrahydroxy-2-oxohexanoic acid, and the molecular formula is C6H10O7, Category: alcohols-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Gujar, Jitendra B. published the artcileSynthesis of Dihydropyrano[2,3-C]pyrazoles Using Mandelic Acid as an Efficient Catalyst, Formula: C8H8O3, the publication is Organic Preparations and Procedures International (2022), 54(2), 138-144, database is CAplus.

A simple new synthetic protocol for the preparation of dihydropyrano[2,3-C]pyrazole derivatives I (R = 4-methylphenyl, piperonyl, Et, etc.) using conventional and US methods with green characteristics. The model reaction was performed using one-pot MCR of Et acetoacetate, hydrazine hydrate, p-methylbenzaldehyde RCHO, and malononitrile in water at reflux or US method, using mandelic acid as an efficient catalyst. The considerable advantages of these methods include short reaction times, very good yields, and the avoidance of the use of environmentally hazardous solvents.

Organic Preparations and Procedures International published new progress about 90-64-2. 90-64-2 belongs to alcohols-buliding-blocks, auxiliary class Carboxylic acid,Benzene,Alcohol,Natural product, name is 2-Hydroxy-2-phenylacetic acid, and the molecular formula is C8H8O3, Formula: C8H8O3.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Cardenas-Castro, Alicia P. published the artcileIn vitro gastrointestinal digestion and colonic fermentation of tomato (Solanum lycopersicum L.) and husk tomato (Physalis ixocarpa Brot.): Phenolic compounds released and bioconverted by gut microbiota, Formula: C8H8O3, the publication is Food Chemistry (2021), 130051, database is CAplus and MEDLINE.

Two of the most important Mexican plant-foods are tomato (Solanum lycopersicum L.) and husk tomato (Physalis ixocarpa Brot.). In this study three objectives were followed: i) to evaluate the bioaccessible phenolic compounds (PC) in T and HT during upper gastrointestinal digestion, ii) to in vitro ferment the indigestible fractions of the samples to evaluate the short-chain fatty acids (SCFA) production, iii) the microbial metabolites, bioconverted PC and volatile organic compounds (VOCs) generated during the fermentation Vanillic acid was the most bioaccessible PC and after 48 h, 3-hydroxyphenylacetic acid was the most abundant microbial metabolite identified in both samples. The identification of VOCs belonging to terpenes (and derivatives) group in T and HT can be product of the microbial metabolism of carotenoids. The study shows new knowledge of the in vitro intestinal digestion and fermentation of T and HT final compounds with biol. potential which should be evaluated in further studies.

Food Chemistry published new progress about 621-37-4. 621-37-4 belongs to alcohols-buliding-blocks, auxiliary class Carboxylic acid,Benzene,Phenol,Natural product, name is 3-Hydroxyphenylacetic acid, and the molecular formula is C8H8O3, Formula: C8H8O3.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts