Tag: M.W=150-200

Alinezhad, Heshmatollah; Pakzad, Khatereh published the artcile< C-S Cross-coupling reaction using novel and green synthesized CuO nanoparticles assisted by Euphorbia maculata extract>, Recommanded Product: 2-(Phenylthio)ethanol, the main research area is copper oxide nanoparticle green catalyst preparation; aqueous Euphorbia maculata copper sulfate extract green biosynthesis; thioether preparation green chem; thiol aryl halide cross coupling CuO nanoparticle catalyst.

In the present study, biosynthesis of CuO nanoparticles using a rapid, eco-friendly, cost-effective and efficient method was reported employing aqueous Euphorbia maculata extract as mild, renewable and non-toxic reducing and capping agents without adding any surfactants. This biogenic and green method had some benefits compared to conventional phys. and chem. methods. The biosynthesized CuO NP displayed a color change pattern (from sky blue to black) on preparation and presented its resp. broad peak at 365 nm, which was analyzed by UV-vis spectroscopy. Using FT-IR anal., biomols. in E. maculata extract which were responsible for bioreduction activity and synthesized CuO NP, were identified. XRD, EDX and FESEM results confirmed successful synthesis of CuO nanoparticles of 18 nm sizes, with spherical and sponge crystal structure. Catalytic activity of biosynthesized CuO NPs was studied in C-S cross-coupling reaction of thiols with aryl halides. This method had the advantages of high yields, easy work-up, and simple reusability. The recovered CuO NP could be reused four times without any considerable loss of its catalytic activity.

Applied Organometallic Chemistry published new progress about Aryl halides Role: RCT (Reactant), RACT (Reactant or Reagent). 699-12-7 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H10OS, Recommanded Product: 2-(Phenylthio)ethanol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Molaei, Somayeh; Ghadermazi, Mohammad published the artcile< Heterogeneously catalyzed selective aerobic oxidation of sulfides with supported Dy on SBA-15 as recyclable catalyst under green condition>, COA of Formula: C8H10OS, the main research area is dysprosium oxopyrrolidine carboxylic acid silica catalyst sulfide green oxidation.

This manuscript presents a simple, efficient and environmentally benign room temperature aerobic catalytic process to the selective oxidation of sulfides to sulfoxides by Dy (III)-substituted 5-oxopyrrolidine-2-carboxylic acid (Glp) immobilized on SBA-15(SBA-15-Glp-Dy). The catalyst could be reused seven cycles without any loss in performance. This is the first selective aerobic oxidation of sulfides using a Dy-based heterogeneous system.

Solid State Sciences published new progress about Green chemistry. 699-12-7 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H10OS, COA of Formula: C8H10OS.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Chen, Qincao; Zhu, Yin; Dai, Weidong; Lv, Haipeng; Mu, Bing; Li, Pengliang; Tan, Junfeng; Ni, Dejiang; Lin, Zhi published the artcile< Aroma formation and dynamic changes during white tea processing>, Product Details of C10H18O, the main research area is aroma compound white tea withering drying; Amino acid; Aroma; GC × GC-TOFMS; Glycosidically bound volatile; White tea.

The formation of and dynamic changes in aroma during white tea processing have not previously been systematically investigated. In this study, advanced comprehensive two-dimensional gas chromatog.-time-of-flight mass spectrometry was employed to investigate the mechanism of white tea aroma formation. A total of 172 volatiles were identified and mainly comprising endogenous volatiles, which displayed diverse change trends during the withering period. In this process, free aroma precursor amino acids and glycosidically bound volatiles (GBVs) were found to contribute to the formation of white tea aroma, with the differential expression of aroma-related key genes accounting for various accumulation of endogenous volatiles and GBVs. In addition, the drying was also shown to play an important role in the formation of white tea aroma. Our study provides the first characterization of white tea aroma formation and establishes a theor. basis for quality control during white tea processing operations.

Food Chemistry published new progress about Drying process. 78-70-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C10H18O, Product Details of C10H18O.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Chaudhuri, Susri Ray; Modak, Arindam; Bhaumik, Asim; Swarnakar, Snehasikta published the artcile< Phloroglucinol derivatives as potential anti-ulcer compound that inhibits matrix metalloproteinase-9>, Related Products of 4396-13-8, the main research area is antiulcer phloroglucinol derivative matrix metalloproteinase 9 gastric ulceration.

Three phloroglucinol based polyphenolic compounds have been synthesized and their potential efficacy against gastric ulceration in mice was investigated. Polyphenol (I, II, III) were synthesized through Vilsmeier-Haack formylation, Schiff-base condensation of diformyl- phloroglucinol with 4-amino salicylic acid and Duff formylation reactions resp. We administered indomethacin, a non-steroidal anti inflammatory drug (NSAID), to induce gastric ulceration in Balb/c mice and tested antiulcer efficacy of synthesized phloroglucinol derivatives The pathogenesis of NSAID-induced ulceration is known to be associated to upregulation of matrix metalloproteinase (MMP)-9. All derivatives of phloroglucinol were found to prevent gastric ulceration in mice through depletion of oxidative stress in gastric tissue. Phloroglucinol derivatives also possessed antioxidant activity and they suppressed antioxidant enzymes in gastric tissues to almost normalcy during gastroprotection. Compound III was found to be most efficient anti-ulcer agent among others that inhibited the MMP-9 activity near to control value during prevention of NSAID-induced gastric ulceration. Thus, new polyphenolic compounds derived from phloroglucinol have antioxidant as well as anti-ulcer activity. We conclude that phloroglucinol derivatives as potent anti-ulcer compound in prevention of indomethacin induced gastric ulceration via attenuation of MMP-9 activity.

International Journal of Pharmaceutical Applications published new progress about Antioxidants. 4396-13-8 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H6O5, Related Products of 4396-13-8.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Guo, Huan; Yuan, Qin; Fu, Yuan; Liu, Wen; Su, Ya-Hong; Liu, Hui; Wu, Chao-Yi; Zhao, Li; Zhang, Qing; Lin, De-Rong; Chen, Hong; Qin, Wen; Wu, Ding-Tao published the artcile< Extraction optimization and effects of extraction methods on the chemical structures and antioxidant activities of polysaccharides from snow chrysanthemum (Coreopsis tinctoria)>, SDS of cas: 3458-28-4, the main research area is coreopsis polysaccharide uronic acid monosaccharide antioxidant UAE MAE; Coreopsis tinctoria; antioxidant activity; chemical structure; extraction optimization; polysaccharide.

In order to explore snow chrysanthemum polysaccharides (SCPs) as functional food ingredients and natural antioxidants for industrial applications, both microwave-assisted extraction (MAE) and ultrasonic-assisted extraction (UAE) were firstly optimized for the extraction of SCPs. Furthermore, the effects of conventional hot water extraction, UAE, and MAE on the chem. structures and antioxidant activities of SCPs were investigated. The maximum extraction yields of SCPs extracted by UAE (4.13 ± 0.24%) and MAE (4.26 ± 0.21%) were achieved at the optimized extraction parameters as follows: ultrasound amplitude (68%) and microwave power (500 W), ultrasound extraction time (21 min) and microwave extraction time (6.5 min), and ratio of liquid to raw material (42.0 mL/g for UAE and 59.0 mL/g for MAE). In addition, different extraction methods significantly affected the contents of uronic acids, the mol. weights, the molar ratio of constituent monosaccharides, and the degree of esterification of SCPs. SCPs exhibited remarkable DPPH (IC50 = 1.702 mg/mL), ABTS (IC50 = 1.121 mg/mL), and nitric oxide (IC50 = 0.277 mg/mL) radical scavenging activities, as well as reducing power (= 80.17 ± 4.8μg Trolox/mg), which suggested that SCPs might be one of the major contributors toward the antioxidant activities of snow chrysanthemum tea. The high antioxidant activities (DPPH, IC50 = 0.693 mg/mL; ABTS, IC50 = 0.299 mg/mL; nitric oxide, IC50 = 0.105 mg/mL; and reducing power, 127.79 ± 2.57μg Trolox/mg) observed in SCP-M extracted by the MAE method might be partially attributed to its low mol. weight and high content of unmethylated galacturonic acids. Results suggested that the MAE method could be an efficient technique for the extraction of SCPs with high antioxidant activity, and SCPs could be further explored as natural antioxidants for industrial application.

Polymers (Basel, Switzerland) published new progress about Antioxidants. 3458-28-4 belongs to class alcohols-buliding-blocks, and the molecular formula is C6H12O6, SDS of cas: 3458-28-4.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Ke, Yanguo; Abbas, Farhat; Zhou, Yiwei; Yu, Rangcai; Yue, Yuechong; Li, Xinyue; Yu, Yunyi; Fan, Yanping published the artcile< Genome-wide analysis and characterization of the Aux/IAA family genes related to floral scent formation in Hedychium coronarium>, Computed Properties of 78-70-6, the main research area is IAA volatile compound floral scent Hedychium; Aux/IAA; HcIAA; Hedychium coronarium; floral scent.

Auxin plays a key role in different plant growth and development processes, including flower opening and development. The perception and signaling of auxin depend on the cooperative action of various components, among which auxin/indole-3-acetic acid (Aux/IAA) proteins play an imperative role. In a recent study, the entire Aux/IAA gene family was identified and comprehensively analyzed in Hedychium coronarium, a scented species used as an ornamental plant for cut flowers. Phylogenetic anal. showed that the Aux/IAA gene family in H. coronarium is slightly contracted compared to Arabidopsis, with low levels of non-canonical proteins. Sequence anal. of promoters showed numerous cis-regulatory elements related to various phytohormones. HcIAA genes showed distinct expression patterns in different tissues and flower developmental stages, and some HcIAA genes showed significant responses to auxin and ethylene, indicating that Aux/IAAs may play an important role in linking hormone signaling pathways. Based on the expression profiles, HcIAA2, HcIAA4, HcIAA6 and HcIAA12, were selected as candidate genes and HcIAA2 and HcIAA4 were screened for further characterization. Downregulation of HcIAA2 and HcIAA4 by virus-induced gene silencing in Hedychium coronarium flowers modified the total volatile compound content, suggesting that HcIAA2 and HcIAA4 play important roles in Hedychium coronarium floral scent formation. The results presented here will provide insights into the putative roles of HcIAA genes and will assist the elucidation of their precise roles during floral scent formation.

International Journal of Molecular Sciences published new progress about Arabidopsis. 78-70-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C10H18O, Computed Properties of 78-70-6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Kim, Min-Gu; Kim, Seong-Man; Min, Jae-Hong; Kwon, Ok-Kyoung; Park, Mi-Hyeong; Park, Ji-Won; Ahn, Hye In; Hwang, Jeong-Yeon; Oh, Sei-Raying; Lee, Jae-Won; Ahn, Kyung-Seop published the artcile< Anti-inflammatory effects of linalool on ovalbumin-induced pulmonary inflammation>, Application In Synthesis of 78-70-6, the main research area is allergic asthma airway inflammation mucus linalool therapeutics; Allergic asthma; Eosinophil; Linalool; Mucus; NF-κB; Th2 cytokines.

Linalool is a natural product present in fruits and aromatic plants with biol. activities. Researchers have reported that the inhalation of linalool exerts anti-inflammatory activities. In this study, we examined the therapeutic effects of linalool on airway inflammation and mucus overproduction in mice with allergic asthma. Oral administration of linalool significantly inhibited the levels of eosinophil numbers, Th2 cytokines and IgE (IgE) caused by ovalbumin (OVA) exposure. Linalool exerted preventive effects against the influx of inflammatory cells and mucus hypersecretion in the lung tissues. Linalool also dose-dependently decreased the levels of inducible nitric oxide synthase (iNOS) expression and protein kinase B (AKT) activation in the lung tissues. Linalool effectively downregulated the activation of mitogen-activated protein kinases (MAPKs) and nuclear factor-kappaB caused by OVA exposure. Furthermore, linalool exerted inhibitory effect on OVA-induced airway hyperresponsiveness (AHR). In the in vitro study, the increased secretion of MCP-1 was attenuated with linalool treatment in lipopolysaccharide (LPS)-stimulated H292 airway epithelial cells. In conclusion, linalool effectively exerts a protective role in OVA-induced airway inflammation and mucus hypersecretion, and its protective effects are closely related to the downregulation of inflammatory mediators and MAPKs/NF-kappaB signaling.

International Immunopharmacology published new progress about Asthma. 78-70-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C10H18O, Application In Synthesis of 78-70-6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Jafari, Fariba; Ghorbani-Choghamarani, Arash; Hasanzadeh, Neda published the artcile< Guanidine complex of copper supported on boehmite nanoparticles as practical, recyclable, chemo and homoselective organic-inorganic hybrid nanocatalyst for organic reactions>, Category: alcohols-buliding-blocks, the main research area is copper immobilized guanidine modified boehmite nanoparticle preparation thermal stability; nitrile copper guanidine modified boehmite nanoparticle catalyst homoselective cycloaddition; phenyl tetrazole preparation; sulfide copper guanidine modified boehmite nanoparticle catalyst chemoselective sulfoxidation; sulfinyl preparation.

Boehmite (BO) nanoparticles (NPs) were prepared via the injection of aqueous NaOH solution to aqueous aluminum nitrate solution at room temperature Afterwards, a new complex of copper was immobilized on BO-NPs (Cu-Guanidine@BO-NPs). This heterogeneous nanocatalyst was used as a practical, recyclable, chemo and homoselective nanocatalyst in the organic processes, i.e. the preparation of tetrazole five-membered heterocycles and chemoselective sulfoxidation of sulfides using H2O2 as oxidant. In this sense, the prepared nanocatalyst was characterized by AAS, N2 adsorption-desorption isotherms, WDX, EDS, SEM, and TGA techniques. The reusability of this catalyst was investigated in the described organic reactions for several runs without notable loss of its catalytic activity. Moreover, all of the tetrazole and sulfoxide derivatives were isolated in high Turn Over Number (TON) and Turn Over Frequency (TOF) numbers indicating the high activity and selectivity of Cu-Guanidine@BO-NPs in the described reactions.

Applied Organometallic Chemistry published new progress about [3+2] Cycloaddition reaction (homoselective). 699-12-7 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H10OS, Category: alcohols-buliding-blocks.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Song, Ya; Zhu, Minqian; Hao, Huili; Deng, Jie; Li, Meiying; Sun, Yuanming; Yang, Ruili; Wang, Hong; Huang, Riming published the artcile< Structure characterization of a novel polysaccharide from Chinese wild fruits (Passiflora foetida) and its immune-enhancing activity>, Electric Literature of 3458-28-4, the main research area is Passiflora polysaccharide immune enhancement; Immune-enhancing activity; Passiflora foetida; Polysaccharide; Structure characterization.

A novel polysaccharide (PFP1) with an average mol. weight of 2.02 × 105 g/mol was isolated from Passiflora foetida fruits through hot water extraction, ethanol precipitation and column chromatog. The structure of PFP1 was determined by GPC-MALS-RI, IC, FT-IR, GC-MS and NMR. The structural anal. showed that PFP1 was a heteropolysaccharide and composed of mannose (48.83%), galactose (32.46%), glucose (6.21%), arabinose (5.88%), fructose (2.24%), galacturonic acid (2.20%), xylose (1.17%), fucose (0.17%), ribose (0.05%), and glucuronic acid (0.78%), with a backbone structure of →1)-α-D-Manp→1,2)-β-D-Manp-linked 1,2,6)-β-D-Manp residues and side chains consisted of →1)-β-D-Galp, →1,4)-α-D-Manp, →1, 4)-β-D-Glcp, →1,3)-α-D-Galp, →1,6)-β-D-Manp, →1,6)-β-D-Galp, →1,2,3)-β-D-Manp and →1,3,6)-β-D-Galp residues. The results of immune-enhancing assays revealed that PFP1 could obviously promote the production of NO and secretion of cytokines (TNF-α and IL-6) of macrophage RAW264.7. These findings demonstrate that P. foetida fruit polysaccharides can be utilized as a potential immune-enhancing functional food.

International Journal of Biological Macromolecules published new progress about Health food (functional). 3458-28-4 belongs to class alcohols-buliding-blocks, and the molecular formula is C6H12O6, Electric Literature of 3458-28-4.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Zhang, Bo; Yu, Pingfeng; Wang, Zijian; Alvarez, Pedro J. J. published the artcile< Hormetic promotion of biofilm growth by polyvalent bacteriophages at low concentrations>, Computed Properties of 492-62-6, the main research area is hormetic promotion biofilm growth polyvalent bacteriophages concentration.

Interactions between bacteriophages (phages) and biofilms are poorly understood despite their broad ecol. and water quality implications. Here, we report that biofilm exposure to lytic polyvalent phages at low concentrations (i.e., 102-104 phages/mL) can counterintuitively promote biofilm growth and densification (corroborated by confocal laser scanning microscopy (CLSM)). Such exposure hormetically upregulated quorum sensing genes (by 4.1- to 24.9-fold), polysaccharide production genes (by 3.7- to 9.3-fold), and curli synthesis genes (by 4.5- to 6.5-fold) in the biofilm-dwelling bacterial hosts (i.e., Escherichia coli and Pseudomonas aeruginosa) relative to unexposed controls. Accordingly, the biofilm matrix increased its polysaccharide and extracellular DNA content relative to unexposed controls (by 41.8 ± 2.3 and 81.4 ± 2.2%, resp.), which decreased biofilm permeability and increased structural integrity. This contributed to enhanced resistance to disinfection with chlorine (bacteria half-lives were 6.08 ± 0.05 vs 3.91 ± 0.03 min for unexposed controls) and to subsequent phage infection (biomass removal was 18.2 ± 1.2 vs 32.3 ± 1.2% for unexposed controls), apparently by mitigating diffusion of these antibacterial agents through the biofilm. Overall, low concentrations of phages reaching a biofilm may result in unintended biofilm stimulation, which might accelerate biofouling, biocorrosion, or other biofilm-related water quality problems.

Environmental Science & Technology published new progress about Antibacterial agents. 492-62-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C6H12O6, Computed Properties of 492-62-6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts