Tag: M.W=150-200

Chen, Yueting; Weng, Yuanyuan; Zhou, Min; Meng, Yiyu; Liu, Jialu; Yang, Lin; Zuo, Zhaojiang published the artcile< Linalool- and α-terpineol-induced programmed cell death in Chlamydomonas reinhardtii>, SDS of cas: 78-70-6, the main research area is Chlamydomonas programmed cell death linalool alpha terpineol algaecide; Algaecide; Chlamydomonas reinhardtii; Linalool; Programmed cell death; α-Terpineol.

Plant allelochems. effectively inhibit and/ or control algal growth, and have potential to use as algaecide. To uncover the lethal mechanism of 2 anti-algal compounds linalool and α-terpineol identified from Cinnamomum camphora extracts, and promote their development as algaecide, the H2O2 production, photosynthetic abilities, H2O2 content burst in linalool treatment at 0.5 h and in α-terpineol treatment at 1 h, with increases of 2.7 folds and 1.3 folds, resp., compared to that at 0 h. The photosynthetic pigments gradually degraded, and Fv/Fm gradually declined to zero, indicating that the cell death was not a necrosis due to the gradual disappearance of physiol. process. In C. reinhardtii cells, the caspase-9-like and caspase-3-like were activated in the treatments with the 2 compounds for 1 h. With prolonging the treatment time, the fluorescent intensity of the cell nucleuses stained by DAPI gradually enhanced and then faded, and the genomic DNA isolated from the cells gradually degraded. These hallmarks indicated that the death of C. reinhardtii cells in linalool and α-terpineol treatments was a (PCD) triggered by the increased reactive oxygen species (ROS). Compared to α-terpineol treatment, linalool treatment showed stronger promoting effects on PCD at the same time point, which may be caused by the higher ROS content inducing higher caspase-9-like and caspase-3-like activities in a short time.

Ecotoxicology and Environmental Safety published new progress about Algicides. 78-70-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C10H18O, SDS of cas: 78-70-6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Nikoorazm, Mohsen; Moradi, Parisa; Noori, Nourolah; Azadi, Gouhar published the artcile< L-Arginine complex of copper on modified core-shell magnetic nanoparticles as reusable and organic-inorganic hybrid nanocatalyst for the chemoselective oxidation of organosulfur compounds>, Synthetic Route of 699-12-7, the main research area is arginine copper complex magnetic nanocatalyst preparation crystallinity; organosulfur compound chemoselective oxidation; sulfoxide green preparation.

The fabrication and characterization of a stable heterogeneous nanostructure catalyst of copper immobilized on Fe3O4@SiO2@L-Arginine, for the oxidation of sulfides and oxidative coupling of thiols was reported. The prepared nanocatalyst was characterized by different techniques such as FTIR, XRD, SEM, TEM and TGA. These nanoparticles were the effective catalyst for selective oxidation of sulfides and oxidative coupling of thiols using 30% H2O2. The suggested method offered several prominent advantages such as mild condition, use of magnetically reusable catalyst, simple workup procedure, good to high yields of products and great selectivity.

Journal of the Iranian Chemical Society published new progress about Crystallinity. 699-12-7 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H10OS, Synthetic Route of 699-12-7.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Mirfakhraei, Saeideh; Hekmati, Malak; Eshbala, Fereshteh Hosseini; Veisi, Hojat published the artcile< Fe3O4/PEG-SO3H as a heterogeneous and magnetically-recyclable nanocatalyst for the oxidation of sulfides to sulfones or sulfoxides>, Electric Literature of 699-12-7, the main research area is sulfide oxidation; sulfoxide preparation; sulfone preparation; magnetite sulfonated oxidation nanocatalyst.

A sulfonated-polyethylene glycol-coated Fe3O4 nanocomposite (Fe3O4/PEG-SO3H) as a greatly effective and ecol. nanocatalyst for the selective oxidation of sulfides to sulfoxides or sulfones with high yields under solvent-free conditions by employing 30% hydrogen peroxide as the oxidant, is presented. A number of sulfides containing alc., ester, and aldehyde functional groups were effectively and selectively oxidized without altering the desired characteristics. The magnetic nanocatalyst (Fe3O4/PEG-SO3H) can be conveniently and swiftly retrieved through the utilization of an external magnetic tool and recycled for more than 10 reaction runs without significantly decreasing its catalytic behavior.

New Journal of Chemistry published new progress about Nanocatalysts. 699-12-7 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H10OS, Electric Literature of 699-12-7.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Tamoradi, Taiebeh; Ghadermazi, Mohammad; Ghorbani-Choghamarani, Arash; Molaei, Somayeh published the artcile< Synthesis and characterization of oxo-vanadium complex anchored onto SBA-15 as a green, novel and reusable nanocatalyst for the oxidation of sulfides and oxidative coupling of thiols>, Quality Control of 699-12-7, the main research area is SBA15 vanadium complex oxidation oxidative coupling catalyst.

The present work describes the synthesis of a new oxo-vanadium complex immobilized on SBA-15 nanostructure as an efficient catalyst for oxidation of sulfides and oxidative coupling of thiols. Characterization of the resultant AMPD@SBA-15 nanostructure was performed by various physico-chem. techniques such as Fourier transform IR spectroscopy, transmission and scanning electron microscopies, energy-dispersive X-ray spectroscopy, inductively coupled plasma optical emission spectroscopy, X-ray diffraction, thermal gravimetric anal., and N2 adsorption and desorption. The results of the developed procedure bring several benefits such as the use of com. available, ecol. benign, operational simplicity, and cheap and chem. inert reagents. It shows good reaction times, practicability and high efficiency, and is easily recovered from the reaction mixture by simple filtration and reused for several consecutive cycles without noticeable change in its catalytic activity. More importantly, high efficiency, simple and an inexpensive procedure, com. available materials, easy separation, and an eco-friendly procedure are the several advantages of the currently employed heterogeneous catalytic system. Graphical Abstract: [Figure not available: see fulltext.].

Research on Chemical Intermediates published new progress about Oxidation catalysts. 699-12-7 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H10OS, Quality Control of 699-12-7.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Chenavas, Sophie; Fiorini-Puybaret, Christel; Joulia, Philippe; Larrouquet, Camille; Waton, Hugues; Martinez, Agathe; Casabianca, Herve; Fabre, Bernard published the artcile< New formylated phloroglucinol compounds from Eucalyptus globulus foliage>, Related Products of 4396-13-8, the main research area is Eucalyptus formylated phloroglucinol compound acylphloroglucinol.

Two new acylphloroglucinols were isolated from the leaves of Eucalyptus globulus Labill and identified as macrocarpals P (1) and Q (2). Structural elucidations were carried out using conventional 1D and 2D NMR and mass spectrometry together with complementary techniques (UV and IR). Macrocarpal Q was a diastereoisomer of macrocarpal E (3), configuration of which was not precised. Simultaneous isolation of macrocarpals E and Q allowed to determine the configurations of both compounds The diformylphloroglucinol (4) was also isolated as well as already known compounds grandinol, macrocarpals D, I, L, N, O and am-1.

Phytochemistry Letters published new progress about Eucalyptus globulus. 4396-13-8 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H6O5, Related Products of 4396-13-8.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Hu, Weichao; Zhao, Yuqing; Yang, Yong; Zhang, Huifang; Ding, Chunbang; Hu, Chao; Zhou, Lijun; Zhang, Zhongwei; Yuan, Shu; Chen, Yanger; Yuan, Ming published the artcile< Microwave-assisted extraction, physicochemical characterization and bioactivity of polysaccharides from Camptotheca acuminata fruits>, Product Details of C6H12O6, the main research area is Camptotheca fruit polysaacharide CAP3 antioxidant immunomodulatory activity; Antioxidant activity; Camptotheca acuminate polysaccharides; Immunomodulatory activity; Microwave-assisted extraction.

Microwave-assisted extraction of polysaccharides from Camptotheca acuminate (CAPs) was optimized by response surface methodol. The optimal parameters were as follows: microwave power, 600 W; liquid-solid ratio, 40:1 g/mL; extraction time, 14 min; and extraction temperature, 70 °C. Under these conditions, the yield of CAPs reached up to 8.61%. CAP-3, an acidic polysaccharide with a mol. weight of 121.34 kDa, was separated and purified from CAPs, which was only composed of glucose and mannose. CAP-3 exhibited strong antioxidant activity against DPPH (IC50: 0.78 mg/mL), hydroxyl radicals (IC50: 0.84 mg/mL) and also showed synergistic antioxidative effect with ascorbic acid in vitro. Meanwhile, CAP-3 could protect plasmid DNA from oxidative damage. Moreover, CAP-3 could improve immunomodulatory activity of RAW264.7 cells through promoting the phagocytosis and nitric oxide release. Therefore, CAP-3 had a strong potential in functional food, pharmaceuticals and cosmetics industries.

International Journal of Biological Macromolecules published new progress about Antioxidants. 3458-28-4 belongs to class alcohols-buliding-blocks, and the molecular formula is C6H12O6, Product Details of C6H12O6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Mizushima, Taiga; Oka, Marina; Imada, Yasushi; Iida, Hiroki published the artcile< Low-Voltage-Driven Electrochemical Aerobic Oxygenation with Flavin Catalysis: Chemoselective Synthesis of Sulfoxides from Sulfides>, Name: 2-(Phenylthio)ethanol, the main research area is sulfoxide preparation chemoselective green chem electrochem; sulfide electrochem aerobic oxygenation flavin catalyst.

The chemoselective electrochem. oxygenation of sulfides RSR1 (R = Ph, Bu, pyridin-2-yl, etc.; R1 = Me, cyclopropyl, prop-2-en-1-yl, etc.) and dithiane to sulfoxides RS(O)R1 and 1,3-dithiane 1-oxide was performed using a biomimetic flavin catalyst that enables the activation of mol. oxygen under a low cathode potential. Diverse functional groups, including alcs., ketones, aldehydes, cyclopropane, carboxylic acids, pyridine, alkenes, and alkynes, are well tolerated under low-voltage electrolytic conditions.

Advanced Synthesis & Catalysis published new progress about Chemoselectivity. 699-12-7 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H10OS, Name: 2-(Phenylthio)ethanol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Jung, Jong-Woon; Damodar, Kongara; Kim, Jin-Kyung; Jun, Jong-Gab published the artcile< First synthesis and in vitro biological assessment of isosideroxylin, 6,8-dimethylgenistein and their analogues as nitric oxide production inhibition agents>, Related Products of 4396-13-8, the main research area is isosideroxylin preparation nitric oxide inhibitory antiinflammatory activity; dimethylgenistein preparation nitric oxide inhibitory antiinflammatory activity; Vilsmeier Haack Friedel Crafts acylation Gammill protocol Suzuki.

A modular and efficient synthesis of the biol. significant C-methylisoflavones isosideroxylin (I), 6,8-dimethylgenistein (II) and their analogs is established for the first time. The synthesis is realized in 7-8 steps in overall yields of 16%-24% from com. inexpensive phloroglucinol and features a high yielding Vilsmeier-Haack reaction, Friedel-Crafts acylation, Gammill’s protocol and Suzuki coupling as the pivotal transformations. Next, these compounds evaluated for their inhibitory potency on the production of nitric oxide (NO) in lipopolysaccharide (LPS)-activated RAW-264.7 cells as an indicator of anti-inflammatory activity. The results showed that all the compounds decreased NO production in a dose-dependent manner without marked cytotoxicity and IC50 values are found in the range of 10.17-33.88 μmol/L. Of note, some compounds show comparable inhibitory activity with pos. control (N-monomethyl-L-arginine, L-NMMA).

Chinese Chemical Letters published new progress about Anti-inflammatory agents. 4396-13-8 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H6O5, Related Products of 4396-13-8.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Bharate, Sandip B.; Khan, Shabana I.; Tekwani, Babu L.; Jacob, Melissa; Khan, Ikhlas A.; Singh, Inder Pal published the artcile< S-Euglobals: Biomimetic synthesis, antileishmanial, antimalarial, and antimicrobial activities>, SDS of cas: 4396-13-8, the main research area is euglobal analog preparation antileishmanial antimalarial antimicrobial structure.

Several new euglobal analogs (named as S-euglobals) were synthesized from phloroglucinol using a biomimetic three-component reaction involving Knoevenagel condensation and Diels-Alder cycloaddition with a monoterpene. Newly synthesized euglobal analogs involve monoterpenes that have not yet been encountered in natural euglobals. S-Euglobals along with previously synthesized robustadial A and B were evaluated for in vitro antileishmanial, antimalarial, antimicrobial, and cytotoxic activities. Out of sixteen analogs prepared, nine analogs were found to exhibit antileishmanial activity against Leishmania donovani promastigotes. A 2-carene-derived S-euglobal was the most potent antileishmanial with IC50 of 2.4 μg/mL and IC90 of 8 μg/mL, followed by a second 2-carene-derived S-euglobal and a nopol-derived S-euglobal (IC50 5.5 and 9.5 μg/mL). Antileishmanial activity of robustadial A (5) and B (6) was moderate with IC50 of 20 and 16 μg/mL, resp. Robustadial A and B and a 2-carene-derived S-euglobal exhibited weak antimalarial activity against Plasmodium falciparum (IC50 of 2.7-4.76 μg/mL). Few of the euglobal analogs showed antibacterial activity against methicillin-resistant Staphylococcus aureus. Amongst these, a nopol-derived S-euglobal was the most potent with IC50 of 1.0 μg/mL and MIC of 5.0 μg/mL. Most of the compounds were not cytotoxic up to 25 μg/mL in a panel of cell lines consisting of both cancer (SK-MEL, KB, BT-549, and SK-OV-3) as well as non-cancer kidney (Vero and LLC-PK11) cells.

Bioorganic & Medicinal Chemistry published new progress about Antimalarials. 4396-13-8 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H6O5, SDS of cas: 4396-13-8.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Do, Thi Bich Thuy; Tran, Bao Khanh; Tran, Thi Van Thi; Le, Trung Hieu; Cnockaert, Margo; Vandamme, Peter; Nguyen, Thi Hong Chuong; Nguyen, Chinh Chien; Hong, Sung Hyun; Kim, Soo Young; Van Le, Quyet published the artcile< Decoding the Capability of Lactobacillus plantarum W1 Isolated from Soybean Whey in Producing an Exopolysaccharide>, Safety of (2S,3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol, the main research area is exopolysaccharide Lactobacillus soybean whey.

This study aims at producing exopolysaccharides (EPS) from a lactic acid bacterial strain. The soybean whey-isolated Lactobacillus plantarum W1 (EPS-W1), which belongs to genus Lactobacillus, is identified using the phenylalanyl-tRNA sequencing method. Of all the examined strains, R-49778 (as numbered by BCCM/LMG Bacteria Collection, Ghent University, Belgium) showed the highest capability of producing exopolysaccharides. Structural characterization revealed a novel exopolysaccharide consisting of repeating units of →6)-D-Glcp-(1→; →3)-D-Manp-(1→; →3)-D-Glcp-(1→ and a branch of →6)-D-Manp-(1→; →2)-D-Glcp-(1→. This discovery opens up avenues for the production of EPS for food industries, functional foods, and biomedical applications.

ACS Omega published new progress about Exopolysaccharides Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 492-62-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C6H12O6, Safety of (2S,3R,4S,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts