Tag: M.W=150-200

Liu, Xue; Cai, Jiaxin; Chen, Haiming; Zhong, Qiuping; Hou, Yaqi; Chen, Weijun; Chen, Wenxue published the artcile< Antibacterial activity and mechanism of linalool against Pseudomonas aeruginosa>, Name: 3,7-Dimethylocta-1,6-dien-3-ol, the main research area is Pseudomonas linalool antibacterial cell membrane permeability; Antibacterial activity; Antibacterial mechanism; Linalool; Pseudomonas aeruginosa.

The purpose of this study was to evaluate the antibacterial activity and mechanism of linalool against Pseudomonas aeruginosa. The determination of antibacterial activity was based on the min. inhibitory concentration (MIC) and the min. bactericide concentration (MBC). Further, the antibacterial mechanism was explored by a growth curve assay, SEM (SEM), cell membrane permeability, membrane potential and respiratory chain dehydrogenase determination The MIC and the MBC of linalool were 431μg/mL and 862μg/mL, resp. The growth curve assay showed that the growth of P. aeruginosa was inhibited. The results of SEM revealed that linalool disrupted the normal morphol. of the cell. The release of nucleic acids as well as the decrease in the membrane potential proved that the membrane integrity of P. aeruginosa was destroyed. Moreover, the respiratory chain was damaged by respiratory chain dehydrogenase determination as the absorbance at 490 nm decreased. This research suggested that it was possible for linalool to become a preservative of food by destroying the cell membrane, resulting in cell death.

Microbial Pathogenesis published new progress about Antibacterial agents. 78-70-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C10H18O, Name: 3,7-Dimethylocta-1,6-dien-3-ol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Molaei, Somayeh; Tamoradi, Taiebeh; Ghadermazi, Mohammad; Ghorbani-Choghamarani, Arash published the artcile< Ordered mesoporous SBA-15 functionalized with yttrium(III) and cerium(III) complexes: Towards active heterogeneous catalysts for oxidation of sulfides and preparation of 5-substituted 1H-tetrazoles>, Synthetic Route of 699-12-7, the main research area is sulfoxide tetrazole preparation SBA 15 functionalized yttrium cerium complex; sulfide nitrile oxidation.

Mesoporous SBA-15 was synthesized and modified with 3-chloropropyltrimethoxysilane and then used in immobilization of creatinine groups, which were employed to introduce Y3+ and Ce3+ to give rise to two novel yttrium and cerium catalysts: SBA-15@Creatinine@M (M = Y and Ce). The structures of the SBA-15@Creatinine@M catalysts were determined using various techniques. These catalysts offered outstanding catalytic performances in the oxidation of sulfides to sulfoxides and in the preparation of 5-substituted 1H-tetrazoles. An important characteristic of the SBA-15@Creatinine@M catalysts is that they are very stable without a considerable decrease in their catalytic performance lasting seven cycles.

Applied Organometallic Chemistry published new progress about IR spectra. 699-12-7 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H10OS, Synthetic Route of 699-12-7.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Ma, Shuang-Jiang; Yu, Jie; Yan, Da-Wei; Wang, Da-Cheng; Gao, Jin-Ming; Zhang, Qiang published the artcile< Meroterpene-like compounds derived from β-caryophyllene as potent α-glucosidase inhibitors>, Formula: C8H6O5, the main research area is meroterpene derivative preparation beta caryophyllene glucosidase inhibitor antidiabetic agent.

Meroterpenoids isolated from guava (Psidium guajava) and Rhodomyrtus tomentosa possess special skeletons which incorporate terpenoids with phloroglucinol derivatives Most of these meroterpenoids showed high cytotoxicity against cancer cell lines. However, their chem. diversity is very limited. Here, we employed a biomimetic hetero-cycloaddition starting from ortho-quinone methides and an abundant natural product, β-caryophyllene, to generate meroterpene-like compounds Considering that the source plant has hyperglycemic functions, α-glucosidase was selected as a target for bioassay. Nine compounds were screened out for promising activities (IC50 < 15 μM), which were better than the pos. controls, genistein and acarbose. The best inhibitor 12 (IC50 = 2.73 μM) possessed 2 caryophyllene moieties. They represented a new type of skeleton possessing activities against α-glucosidase. The kinetic study exhibited that these inhibitors belong to a non-competitive type. All of these inhibitors may provide an opportunity to develop a new class of antidiabetic agents. Organic & Biomolecular Chemistry published new progress about Antidiabetic agents. 4396-13-8 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H6O5, Formula: C8H6O5.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Guo, M.-Z.; Meng, M.; Duan, S.-Q.; Feng, C.-C.; Wang, C.-L. published the artcile< Structure characterization, physicochemical property and immunomodulatory activity on RAW264.7 cells of a novel triple-helix polysaccharide from Craterellus cornucopioides>, Recommanded Product: (2S,3S,4R,5R)-2,3,4,5,6-Pentahydroxyhexanal, the main research area is Craterellus macrophage immunomodulation polysaccharide; Chemical structure; Craterellus cornucopioides; Polysaccharide; Stability immunomodulatory activity.

In the study, a new triple-helix polysaccharide with favorable stability was purified from C. cornucopioides. Its structural characterization, stability and solution behavior were investigated by the GC-MS, periodate oxidation-smith degradation, FT-IR, 1D and 2D NMR spectroscopy, methylation anal., Scanning electron microscope, Congo-red, CD, TGA and DSC anal. The results showed that Craterellus cornucopioide polysaccharide (CCP) possessed the mol. weight of 1.97 × 103 kDa, is mainly composed of mannose (48.73%), galactose (17.37%), glucose (15.97%) and xylose (17.93%), resp. It was a heteroglycan with (1 → 3)-linked-β-D-Manp-(1 → 6)-linked a-D-Galp backbone distributed by (1 → 4)-linked-a-D-Xylp-t-a-D-Manp and t-β-D-Glup units at O-6. The result of TGA and DSC assay indicated that CCP has a favorable thermal stability. MTT and Scanning electro microscopy (SEM) assay showed that CCP could significantly improve the proliferation activity and induce cells activation of RAW264.7 in a certain range of concentrations and period.

International Journal of Biological Macromolecules published new progress about Carbohydrates Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 3458-28-4 belongs to class alcohols-buliding-blocks, and the molecular formula is C6H12O6, Recommanded Product: (2S,3S,4R,5R)-2,3,4,5,6-Pentahydroxyhexanal.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Pang, Xueli; Yu, Weisong; Cao, Changdai; Yuan, Xiaoxiang; Qiu, Jun; Kong, Fanyu; Wu, Jihong published the artcile< Comparison of Potent Odorants in Raw and Ripened Pu-Erh Tea Infusions Based on Odor Activity Value Calculation and Multivariate Analysis: Understanding the Role of Pile Fermentation>, Recommanded Product: 3,7-Dimethylocta-1,6-dien-3-ol, the main research area is odorant raw ripened Pu erh tea pile fermentation; aroma extract dilution analysis (AEDA); odor active marker; odor activity value (OAV); odor threshold (OT); pu-erh tea infusion.

Infusions prepared from raw pu-erh tea (RAPT) and ripened pu-erh tea (RIPT) showed remarkable aroma differences. Predominant odorants in RAPT and RIPT infusions were identified and compared by the combined use of gas chromatog.-olfactometry, aroma extract dilution anal., odor activity values (OAVs), and multivariate anal. A total of 35 and 19 odorants (OAV > 1) were detected in RIPT and RAPT, resp. Odorants in RAPT and RIPT are significantly different in both odor properties and aroma compound intensities. Overall, RAPT contained a complex variety of chem. classes with diverse odors and moderate odor intensities, while RIPT is dominated by structurally and organoleptically similar compounds with high potency. Specifically, stale and musty smelling methoxybenzenes contributed the most to RIPT, while floral-, sweet-, and woody-smelling terpene alcs., terpene ketones, and phenolic compounds were the predominant odorants in RAPT. Orthogonal partial least squares discriminant anal. revealed that linalool, α-ionone, 1,2,4-trimethoxybenzene, 1,2,3-trimethoxy-5-methylbenzene, 1,2,3,4-tetramethoxybenzene, and 1,2,3-trimethoxybenzene underwent remarkable changes during pile fermentation and could be used as potential odor-active markers for RIPT and RAPT discrimination. The comprehensive aroma characterization of pu-erh tea and determination of the effect of pile fermentation on odorant alteration herein will provide guidance for pu-erh tea flavor quality control and evaluation.

Journal of Agricultural and Food Chemistry published new progress about Fermentation (pile). 78-70-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C10H18O, Recommanded Product: 3,7-Dimethylocta-1,6-dien-3-ol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Porter, Ashlin G.; Hu, Hanfeng; Liu, Xuemei; Raghavan, Adharsh; Adhikari, Sarju; Hall, Derrick R.; Thompson, Dylan J.; Liu, Bin; Xia, Yu; Ren, Tong published the artcile< Heptamolybdate: a highly active sulfide oxygenation catalyst>, Application In Synthesis of 699-12-7, the main research area is crystal structure heptamolybdate preparation sulfide oxidation catalyst kinetics sulfone.

The sulfide oxygenation activities of both heptamolybdate ([Mo7O24]6-, [1]6-) and its peroxo adduct [Mo7O22(O2)2]6- ([2]6-) were examined in this contribution. [Mo7O22(O2)2]6- was prepared in a yield of 65% from (NH4)6[Mo7O24] (1a) upon treatment of 10 equiv of H2O2 and structurally identified through single crystal x-ray diffraction study. (Bu4N)6[Mo7O22(O2)2] (2b) is an efficient catalyst for the sequential oxygenation of Me Ph sulfide (MPS) by H2O2 to the corresponding sulfoxide and subsequently sulfone with a 100% utility of H2O2. Surprisingly, (Bu4N)6[Mo7O24] (1b) is a significantly faster catalyst than 2b for MPS oxygenation under identical conditions. The pseudo-first order kcat constants from initial rate kinetics are 54 M-1 s-1 and 19 M-1 s-1 for 1b and 2b, resp. Electrospray ionization mass spectrometry (ESI-MS) study of 1b under the catalytic reaction conditions revealed that [Mo2O11]2- is likely the main active species in sulfide oxygenation by H2O2.

Dalton Transactions published new progress about Crystal structure. 699-12-7 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H10OS, Application In Synthesis of 699-12-7.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Coll Araoz, M. V.; Jacobi, V. G.; Fernandez, P. C.; Luft Albarracin, E.; Virla, E. G.; Hill, J. G.; Catalan, C. A. N. published the artcile< Volatiles mediate host-selection in the corn hoppers Dalbulus maidis (Hemiptera: Cicadellidae) and Peregrinus maidis (Hemiptera: Delphacidae)>, Computed Properties of 78-70-6, the main research area is volatile organic compound Dalbulus Peregrinus; Auchenorrhyncha; leafhopper; olfactometry; planthopper; volatile organic compounds.

Volatile organic compounds (VOCs) released by plants are generally involved in host recognition and host selection for many phytophagous insects. However, for leafhoppers and planthoppers, host recognition is mainly thought to involve a phototactic response, but it is not clear if a host plant could be selected based on the volatile cues it emits. In this study we evaluated olfactory responses in dual choice tests of two Hemiptera species, Dalbulus maidis (De Long) (Cicadellidae) and Peregrinus maidis (Ashmead) (Delphacidae), vectors of maize-stunting diseases, to three maize (Zea mays L.) germplasms, a temperate and a tropical hybrid and a landrace. VOCs emitted by the germplasms were collected and identified using gas chromatog.-mass spectrometry. The temperate hybrid released significantly more VOCs than the tropical hybrid and the landrace, and its volatile profile was dominated by (±)-linalool. D. maidis preferred odours emitted from the temperate hybrid, whereas P. maidis preferred odours from the tropical hybrid and the landrace over the temperate one. In order to test if linalool plays a role in the behavioral responses, we assayed this compound in combination with the tropical hybrid, to provide other contextual olfactory cues. D. maidis was attracted to the tropical hybrid plus a 0.0001% linalool solution, indicating that this compound could be part of a blend of attractants. Whereas addition of linalool resulted in a slight, though not significant, reduction in host VOC attractiveness for P. maidis. Both hopper species responded to olfactory cues in the absence of supplementary visual cues.

Bulletin of Entomological Research published new progress about Behavior. 78-70-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C10H18O, Computed Properties of 78-70-6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Abraham, Raymond J.; Cooper, M. Ashley; Reid, Matthew published the artcile< The use of MM/QM calculations of 13C chemical shifts in the conformational analysis of some monosaccharides and sucrose>, Formula: C6H12O6, the main research area is MM QM conformational monosaccharide sucrose crystal structure.

The 13C NMR chem. shifts of some common pyranose monosaccharides in D2O solution were predicted using a combined mol. mechanics (Pcmod 9.1/MMFF94) and ab initio (GIAO (B3LYP/DFT, 6-31G(d))) model. This method has been successfully used for a range of organic mols. in CDCl3 solution but has not previously been used for aqueous solutions The method gave such good agreement with experiment that the populations of the conformers at C6 of the monosaccharides could be obtained. This has been attempted previously by various methods with diverse results. In all the compounds studied the α and β anomers have similar populations. In glucose the populations of the GG and GT conformers are ca equal with TG a minor component, in galactose GT has the largest population and GG the smallest, in mannose GG is preferred with TG a minor component and in talose GT and TG are favored with GG a minor constituent. The results are in general agreement with previous work. To our knowledge this is the first time that 13C shifts have been used to determine sugar conformations in solution The conformation of sucrose in D2O solution was examined by both 1H and 13C NMR. The complete anal. of the 1H NMR spectrum has been achieved and provides information on the preferred conformations of the CH2OH fragments at G6 (GG) and F6 (GG, GT). Calculations of the 13C shifts confirm these results and show also that the conformation at F1 is mainly GG plus TG. The sucrose conformational profile in solution includes the crystal structure together with the above conformations at F1 and F6.

New Journal of Chemistry published new progress about Ab initio methods. 492-62-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C6H12O6, Formula: C6H12O6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Salarbashi, Davoud; Bazeli, Javad; Fahmideh-Rad, Elham published the artcile< Fenugreek seed gum: Biological properties, chemical modifications, and structural analysis- A review>, Application In Synthesis of 3458-28-4, the main research area is review Fenugreek seed gum physicochem functional property; Fenugreek seed gum; Functional properties; Physico-chemical properties.

A review. Fenugreek is a leguminous plant belongs to the family Fabaceae, which is extensively cultivated as a semiarid crop in Northern Africa, the Mediterranean, India, and Canada. In the present review paper, first we summarized the extraction, purification, chem. composition, mol. structure, and rheol. behavior of the mucilages isolated from Fenugreek seeds (FSG), and then their functional properties presented to elucidate the potential application of this traditional source of hydrocolloids in food, pharmaceutical, and other industries. To date, there is no technique that can successfully remove the attached protein from FSG. From a structural point of view, galactose and mannose are the most abundant polysaccharide in FSG composition, suggesting a galactomannan-like structure. FSG is the most soluble of the seed gums. FSG solutions at various temperatures and concentrations showed a time-dependent shear thinning behavior. Furthermore, these hydrocolloids can be employed for the fabrication of eco-friendly packaging systems. Antioxidant capacity and anti-fungi activity of FSG has been proved in different studies. In conclusion, industrial applications of FSG are possible due to its strong thickening properties. Addnl., FSG has an excellent emulsification capacity, which enables its application in the food, cosmetic and/or pharmaceutical industries.

International Journal of Biological Macromolecules published new progress about Antioxidants. 3458-28-4 belongs to class alcohols-buliding-blocks, and the molecular formula is C6H12O6, Application In Synthesis of 3458-28-4.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Zeng, Fanke; Chen, Wenbo; He, Ping; Zhan, Qiping; Wang, Qian; Wu, Hui; Zhang, Mengmeng published the artcile< Structural characterization of polysaccharides with potential antioxidant and immunomodulatory activities from chinese water chestnut peels>, Product Details of C6H12O6, the main research area is Eleocharis polysaccharide antioxidant immunomodulation; Antioxidant activity; Chinese water chestnut peels; Immunomodulatory activity; Polysaccharides; Structural features.

Chinese water chestnut peels are a kind of vegetable processing waste containing many active components such as polysaccharides, the structure of which remains unknown. To elucidate the structure of polysaccharides from Chinese water chestnut peels, two polysaccharides named WVP-1 and WVP-2 were isolated. WVP-1 (3.16 kDa) consisted of mannose (1.75%), glucose (84.69%), galactose (6.32%), and arabinose (7.24%), while WVP-2 (56.97 kDa) was composed of mannose (3.18%), rhamnose (1.52%), glucuronic acid (1.42%), galacturonic acid (4.83%), glucose (11.51%), galactose (36.02%), and arabinose (41.53%). Linkage and NMR data indicated that WVP-1 was composed mainly of →4)-α-D-Glcp(1→ and a certain proportion of →3)-β-D-Glcp-(1→, including linear and branched polysaccharides simultaneously. WVP-2 was a pectin-like polysaccharide with →4)-α-D-GalpA6Me-(1→ units and the branch points of →3,4)-α-L-Arap-(1→, →3,6)-β-D-Galp-(1→. WVP-2 exhibited stronger potential antioxidant and immunomodulatory activities than WVP-1 in vitro. These results provide a foundation for the further study of polysaccharides from Chinese water chestnut peels.

Carbohydrate Polymers published new progress about Antioxidants. 3458-28-4 belongs to class alcohols-buliding-blocks, and the molecular formula is C6H12O6, Product Details of C6H12O6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts