Tag: M.W=150-200

Skolia, Elpida; Gkizis, Petros L.; Nikitas, Nikolaos F.; Kokotos, Christoforos G. published the artcile< Photochemical aerobic oxidation of sulfides to sulfoxides: the crucial role of wavelength irradiation>, COA of Formula: C8H10OS, the main research area is sulfoxide green preparation; sulfide aerobic photochem oxidation.

Herein, a novel, sustainable, light-driven protocol was reported for photochem. aerobic oxidation of sulfides to sulfoxides RS(O)R1 [R = Ph, naphth-2-yl, n-Bu, etc.; R1 = Me, Et, n-Pr, etc.], where the impact of wavelength irradiation on sulfide aerobic photooxidation was examined In this work, two different low-catalyst loading (0.05-0.5 mol%) protocols, utilizing anthraquinone as the photocatalyst (under CFL lamps or 427 nm irradiation) were developed and a catalyst-free protocol (under 370 nm irradiation) was also assessed. In addition, a broad scope of substrates was tested and extensive mechanistic studies were performed, in order to distinguish the mechanistic pathways that were followed in the different cases of aryl or alkyl sulfide oxidation under different wavelength irradiation Also implemented this protocols toward the oxidation of several intermediates en route to Sulforaphane.

Green Chemistry published new progress about Bromoalkanes Role: RCT (Reactant), RACT (Reactant or Reagent). 699-12-7 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H10OS, COA of Formula: C8H10OS.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Ghorbani-Choghamarani, Arash; Mohammadi, Masoud; Tamoradi, Taiebeh; Ghadermazi, Mohammad published the artcile< Covalent immobilization of Co complex on the surface of SBA-15: Green, novel and efficient catalyst for the oxidation of sulfides and synthesis of polyhydroquinoline derivatives in green condition>, Related Products of 699-12-7, the main research area is silica cobalt complex catalyst polyhydroquinoline sulfoxide synthesis sulfide oxidation.

In this work, a green and novel catalyst was prepared through immobilization of cobalt complex on the surface of mesostructured SBA-15 and characterized by TGA, SEM, FT-IR, EDX, ICP, BET and X-ray mapping anal. methods. This mesostructural material was used as an efficient and green interphase catalyst for the oxidation reactions and synthesis of polyhydroquinoline derivatives All reactions were performed in short times and good yields. Moreover, the prepared catalyst could be used up to six runs without significant degradation in its catalytic activity or cobalt leaching.

Polyhedron published new progress about Green catalysts. 699-12-7 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H10OS, Related Products of 699-12-7.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Natsch, Andreas; Nagelin, Marco; Leijs, Hans; van Strien, Michel; Gimenez-Arnau, Elena; Vey, Matthias; Gonzalez, Cecile published the artcile< Exposure source for skin sensitizing hydroperoxides of limonene and linalool remains elusive: An analytical market surveillance>, Computed Properties of 78-70-6, the main research area is Consumer products; Market surveillance; Quantification; Skin allergy; Terpene hydroperoxides.

Pos. patch test reactions of dermatol. patients to oxidized samples of linalool and limonene are frequently reported. The sensitizing ingredients in the oxidation mixtures are hydroperoxides (HP). It is not clear whether fragranced consumer products are a relevant exposure source for HP. Anal. methodologies had been validated, allowing quantification of HP in different consumer products. The anal. approach was used to analyze 104 consumer products. Samples included aged and new samples from the same brand, products suspected by patients to elicit their symptoms and products containing essential oils. Only four samples contained >50 μg/g of at least one of the HP by the screening method. Confirmatory anal. by LC-MS methods indicated that levels are even below those observed by the conservative screening method. The samples retrieved from patch-test pos. patients were below detection limit for all target analytes. This market surveillance indicates that concentrations of HP in consumer products and patient products are orders of magnitude below sensitizing doses in animal tests. No evidence for hydroperoxide accumulation in aged products or products used by patients was found. The nature and source of the inducing agent responsible for the frequent pos. patch test reactions to oxidized terpenes remains elusive.

Food and Chemical Toxicology published new progress about 78-70-6. 78-70-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C10H18O, Computed Properties of 78-70-6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Ghorbani-Choghamarani, Arash; Seydyosefi, Zeinab; Tahmasbi, Bahman published the artcile< Tribromide ion supported on boehmite nanoparticles as a reusable catalyst for organic reactions>, Reference of 699-12-7, the main research area is sulfoxide preparation chemoselective; sulfide sulfoxidation tribromide ion nanocatalyst; dihydroquinazolinone preparation; benzaldehyde anthranilamide condensation tribromide ion nanocatalyst; polyhydroquinoline preparation; dimedone benzaldehyde ethyl acetoacetate ammonium acetate condensation tribromide ion.

Boehmite nanoparticles are not air or moisture sensitive; therefore, they were prepared in water at room temperature using inexpensive materials, without inert atm., by a very simple and inexpensive procedure. When the surface of boehmite nanoparticles was modified by N,N,N’,N’-tetraethyldiethylenetriamine (TEDETA), tribromide ions became immobilized on modified boehmite nanoparticles (Br3-TEDETA@Boehmite). These materials were characterized by Fourier transform IR spectroscopy, thermogravimetric anal., Brunauer-Emmett-Teller, X-ray diffraction, energy-dispersive X-ray spectroscopy, and SEM techniques. Finally, the catalytic activity of Br3-TEDETA@Boehmite was examined in the selective oxidation of sulfides R1SR2 [R1 = Ph, Me, (CH2)2CH3, etc.; R1R2 = -(CH2)4-; R2 = Me, benzyl, (CH2)2OH, etc.] to sulfoxides R1S(O)R2. Besides, the catalytic activity of Br3-TEDETA@Boehmite was extended to the synthesis of organic heterocyclic compounds, such as 2,3-dihydroquinazolin-4(1H)-one I [R3 = 4-Cl, 4-NO2, 3,4-(OMe)2, etc.] and polyhydroquinoline derivatives II [R4 = 2,3-(Cl)2, 3-NO2, 4-OEt, etc.]. This catalyst was reused several times without significant loss of its catalytic efficiency.

Comptes Rendus Chimie published new progress about Benzaldehydes Role: RCT (Reactant), RACT (Reactant or Reagent). 699-12-7 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H10OS, Reference of 699-12-7.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Tamoradi, Taiebeh; Taheri, Atefeh; Vahedi, Shima; Ghadermazi, Mohammad published the artcile< Gd (III) and Tb (III) immobilized tryptophan functionalized magnetic nanoparticles for eco-friendly oxidation rections>, Safety of 2-(Phenylthio)ethanol, the main research area is sulfide thiol oxidation gadolinium terbium tryptophan magnetic nanoparticle catalyst.

In this study, Gd (III) and Td (III) immobilized magnetic nanocatalysts were prepared following a simple procedure using available materials. These nanoparticles were characterized by FT-IR, XRD, TGA, EDX, and ICP-OES studies and utilized in the S-oxidation reactions. It was observed that the rate of oxidation with Tb magnetic nanocatalyst was higher than that of Gd. Significant advantages of this environmental friendly process include short reaction times, high efficiency, and convenient recovery and reusability of the catalyst for several times without any significant loss of activity.

Solid State Sciences published new progress about Magnetic nanoparticles. 699-12-7 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H10OS, Safety of 2-(Phenylthio)ethanol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Gas-Pascual, Elisabet; Ichikawa, Hiroshi Travis; Sheikh, Mohammed Osman; Serji, Mariam Isabella; Deng, Bowen; Mandalasi, Msano; Bandini, Giulia; Samuelson, John; Wells, Lance; West, Christopher M. published the artcile< CRISPR/Cas9 and glycomics tools for toxoplasma glycobiology>, Safety of (2S,3S,4R,5R)-2,3,4,5,6-Pentahydroxyhexanal, the main research area is genome editing CRISPR Cas9 glycome Toxoplasma human infection; CRISPR/Cas; Toxoplasma gondii; glycan; glycobiology; glycogene; glycomics; glycosyltransferase; mass spectrometry (MS); parasitology; protein glycosylation.

Infection with the protozoan parasite Toxoplasma gondii is a major health risk owing to birth defects, its chronic nature, ability to reactivate to cause blindness and encephalitis, and high prevalence in human populations. Unlike most eukaryotes, Toxoplasma propagates in intracellular parasitophorous vacuoles, but like nearly all other eukaryotes, Toxoplasma glycosylates many cellular proteins and lipids and assembles polysaccharides. Toxoplasma glycans resemble those of other eukaryotes, but species-specific variations have prohibited deeper investigations into their roles in parasite biol. and virulence. The Toxoplasma genome encodes a suite of likely glycogenes expected to assemble N-glycans, O-glycans, a C-glycan, GPI-anchors, and polysaccharides, along with their precursors and membrane transporters. To investigate the roles of specific glycans in Toxoplasma, here we coupled genetic and glycomics approaches to map the connections between 67 glycogenes, their enzyme products, the glycans to which they contribute, and cellular functions. We applied a double-CRISPR/Cas9 strategy, in which two guide RNAs promote replacement of a candidate gene with a resistance gene; adapted MS-based glycomics workflows to test for effects on glycan formation; and infected fibroblast monolayers to assess cellular effects. By editing 17 glycogenes, we discovered novel Glc0-2-Man6-GlcNAc2-type N-glycans, a novel HexNAc-GalNAc-mucin-type O-glycan, and Tn-antigen; identified the glycosyltransferases for assembling novel nuclear O-Fuc-type and cell surface Glc-Fuc-type O-glycans; and showed that they are important for in vitro growth. The guide sequences, editing constructs, and mutant strains are freely available to researchers to investigate the roles of glycans in their favorite biol. processes.

Journal of Biological Chemistry published new progress about Amplicon Role: BUU (Biological Use, Unclassified), BIOL (Biological Study), USES (Uses) (DHFR). 3458-28-4 belongs to class alcohols-buliding-blocks, and the molecular formula is C6H12O6, Safety of (2S,3S,4R,5R)-2,3,4,5,6-Pentahydroxyhexanal.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Heindel, Daniel W.; Koppolu, Sujeethraj; Zhang, Yue; Kasper, Brian; Meche, Lawrence; Vaiana, Christopher A.; Bissel, Stephanie J.; Carter, Chalise E.; Kelvin, Alyson A.; Elaish, Mohamed; Lopez-Orozco, Joaquin; Zhang, Bin; Zhou, Bin; Chou, Tsui-Wen; Lashua, Lauren; Hobman, Tom C.; Ross, Ted M.; Ghedin, Elodie; Mahal, Lara K. published the artcile< Glycomic analysis of host response reveals high mannose as a key mediator of influenza severity>, Reference of 3458-28-4, the main research area is mannose lectin MBL2 Influenza virus infection glycomic; MBL2; lectin array; lectin microarray; mannan binding lectin; mannose binding lectin.

Influenza virus infections cause a wide variety of outcomes, from mild disease to 3 to 5 million cases of severe illness and ∼290,000 to 645,000 deaths annually worldwide. The mol. mechanisms underlying these disparate outcomes are currently unknown. Glycosylation within the human host plays a critical role in influenza virus biol. However, the impact these modifications have on the severity of influenza disease has not been examined Herein, we profile the glycomic host responses to influenza virus infection as a function of disease severity using a ferret model and our lectin microarray technol. We identify the glycan epitope high mannose as a marker of influenza virus-induced pathogenesis and severity of disease outcome. Induction of high mannose is dependent upon the unfolded protein response (UPR) pathway, a pathway previously shown to associate with lung damage and severity of influenza virus infection. Also, the mannan-binding lectin (MBL2), an innate immune lectin that neg. impacts influenza outcomes, recognizes influenza virus-infected cells in a high mannose-dependent manner. Together, our data argue that the high mannose motif is an infection-associated mol. pattern on host cells that may guide immune responses leading to the concomitant damage associated with severity.

Proceedings of the National Academy of Sciences of the United States of America published new progress about Epitopes (glycan). 3458-28-4 belongs to class alcohols-buliding-blocks, and the molecular formula is C6H12O6, Reference of 3458-28-4.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Molaei, Somayeh; Ghadermazi, Mohammad published the artcile< Selective and efficient oxidation of sulfides and thiols to their corresponding sulfoxides and disulfides catalyzed with praseodymium (III) and dysprosium (III) isonicotinamide (INA) complexes grafted onto modified mesoporous MCM-41>, Formula: C8H10OS, the main research area is sulfide thiol oxidation praseodymium dysprosium isonicotinamide complex.

Praseodymium (III) and dysprosium (III) isonicotinamide (INA) complexes grafted onto modified mesoporous MCM-41 with 3-chloropropyltriethoxysilane (CPTES), as two novel catalysts, were synthesized. The catalysts were determined using SEM, Mapping, EDX, FT-IR, TGA, XRD, ICP, and BET anal. The catalysts (MCM-41-INA-Pr and MCM-41-INA-Dy) were further studied for the oxidation reaction of sulfur-containing compounds Catalytic results displayed that the MCM-41-INA-Pr and MCM-41-INA-Dy show high effectiveness for promoting the oxidation reaction of sulfur-containing compounds The catalysts could be recycled for seven runs with negligible destruction of catalytic performance.

Solid State Sciences published new progress about Adsorption. 699-12-7 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H10OS, Formula: C8H10OS.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Gallegos, Felipe E.; Meneses, Lorena M.; Cuesta, Sebastian A.; Santos, Juan C.; Arias, Josefa; Carrillo, Pamela; Pilaquinga, Fernanda published the artcile< Computational Modeling of the Interaction of Silver Clusters with Carbohydrates>, Product Details of C6H12O6, the main research area is computational modeling interaction silver cluster carbohydrate.

Silver nanoparticles are recognized for their numerous phys., biol., and pharmaceutical applications. In the present study, the interaction of silver clusters with monosaccharide mols. is examined to identify which mol. works better as a reducing agent in the application of a green synthesis approach. Geometry optimization of clusters containing one, three, and five silver atoms is performed along with the optimization of α-D-glucose, α-D-ribose, D-erythrose, and glyceraldehyde using d. functional theory. Optimized geometries allow identifying the interaction formed in the silver cluster and monosaccharide complexes. An electron localization function anal. is performed to further analyze the interaction found and explain the reduction process in the formation of silver nanoparticles. The overall results indicate that glyceraldehyde presents the best characteristics to serve as the most efficient reducing agent.

ACS Omega published new progress about Complexation. 492-62-6 belongs to class alcohols-buliding-blocks, and the molecular formula is C6H12O6, Product Details of C6H12O6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Liu, Kai-Jian; Wang, Zheng; Lu, Ling-Hui; Chen, Jin-Yang; Zeng, Fei; Lin, Ying-Wu; Cao, Zhong; Yu, Xianyong; He, Wei-Min published the artcile< Synergistic cooperative effect of CF3SO2Na and bis(2-butoxyethyl)ether towards selective oxygenation of sulfides with molecular oxygen under visible-light irradiation>, Product Details of C8H10OS, the main research area is sulfone sulfoxide synthesis selective synthesis oxidation sulfide.

A safe, practical and eco-friendly method for the switchable synthesis of sulfoxides and sulfones through visible-light-initiated oxygenation of sulfides at ambient temperature under transition-metal-, additives-free and minimal solvent conditions. The synergistic catalytic efforts between CF3SO2Na and 2-butoxyethyl ether represents the key promoting factor for the reaction.

Green Chemistry published new progress about Oxidation. 699-12-7 belongs to class alcohols-buliding-blocks, and the molecular formula is C8H10OS, Product Details of C8H10OS.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts