Tag: M.W=100-200

Product Details of 1195-58-0. The mechanism of aromatic electrophilic substitution of aromatic heterocycles is consistent with that of benzene. Compound: Pyridine-3,5-dicarbonitrile, is researched, Molecular C7H3N3, CAS is 1195-58-0, about Organosilicon compounds. XX. Synthesis of aromatic diamines via trimethylsilyl-protecting aniline intermediates. Author is Pratt, J. Richard; Massey, W. Dale; Pinkerton, Frank H.; Thames, Shelby F..

A synthetic approach utilizing a Me3Si protecting group was used to produce Si and diketo containing diamines. Thus, the halogen-metal interchange of N,N-bis(trimethylsilyl)bromoanilines with BuLi in ether produced Li derivatives, which were treated with dichloro silanes or dinitriles to afford the N,N-bis(trimethylsilyl)silicon containing dianilines or the corresponding lithioimines, resp. Hydrolysis removed the trimethylsilyl protecting groups and converted the lithioimines to the carbonyl compounds to afford the free diamines.

Compounds in my other articles are similar to this one(Pyridine-3,5-dicarbonitrile)Product Details of 1195-58-0, you can compare them to see their pros and cons in some ways,such as convenient, effective and so on.

Reference:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Heterocyclic compounds can be divided into two categories: alicyclic heterocycles and aromatic heterocycles. Compounds whose heterocycles in the molecular skeleton cannot reflect aromaticity are called alicyclic heterocyclic compounds. Compound: 7661-33-8, is researched, Molecular C10H10ClNO, about Scope and selectivity in palladium-catalyzed directed C-H bond halogenation reactions, the main research direction is haloarom compound regioselective preparation; aromatic compound halogenation palladium.Application of 7661-33-8.

Palladium-catalyzed ligand directed C-H activation/halogenation reactions have been extensively explored. Both the nature of the directing group and the substitution pattern on the arene ring of the substrate lead to different reactivity profiles, and often different and complementary products, in the presence and absence of the catalyst.

In some applications, this compound(7661-33-8)Application of 7661-33-8 is unique.If you want to know more details about this compound, you can contact with the author or consult more relevant literature.

Reference:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Related Products of 7661-33-8. Aromatic compounds can be divided into two categories: single heterocycles and fused heterocycles. Compound: 1-(4-Chlorophenyl)pyrrolidin-2-one, is researched, Molecular C10H10ClNO, CAS is 7661-33-8, about Utilization of Cyclic Amides as Masked Aldehyde Equivalents in Reductive Amination Reactions. Author is Prince, Robin J.; Gao, Fang; Pazienza, Jessica E.; Marx, Isaac E.; Schulz, Jurgen; Hopkins, Brian T..

An operationally simple protocol has been discovered that couples primary or secondary amines with N-aryl-substituted lactams to deliver differentiated diamines in moderate to high yields. The process allows for the partial reduction of a lactam in the presence of Cp2ZrHCl (Schwartz’s reagent), followed by a reductive amination between the resulting hemiaminal and primary or secondary amine. These reactions can be telescoped in a one-pot fashion to significantly simplify the operation. The scope of amines and substituted lactams of various ring sizes was demonstrated through the formation of a range of differentiated diamine products. Furthermore, this methodol. was expanded to include N-aryl pyrrolidinone substrates with an enantiopure ester group at the 5-position, and α-amino piperidinones were prepared with complete retention of stereochem. information. The development of this chem. has enabled the consideration of lactams as useful synthons.

In some applications, this compound(7661-33-8)Related Products of 7661-33-8 is unique.If you want to know more details about this compound, you can contact with the author or consult more relevant literature.

Reference:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Application of 1195-58-0. So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic. Compound: Pyridine-3,5-dicarbonitrile, is researched, Molecular C7H3N3, CAS is 1195-58-0, about Two-Phase Oxidations with Aqueous Hydrogen Peroxide Catalyzed by Amphiphilic Pyridinium and Diazinium Salts.

Amphiphilic pyridinium and diazinium salts were shown to be effective catalysts in two-phase (water/chloroform or water/dichloromethane) sulfoxidations and N-oxidations with hydrogen peroxide under mild conditions. This unprecedented oxidation method utilizes covalent bonding of hydrogen peroxide to a simple pyridinium or diazinium nucleus to increase the lipophilicity of the hydroperoxide species and to subsequently activate it for oxidations in a non-polar medium. The catalytic efficiency was found to depend on the type of heteroarenium core and on the lipophilicity of the catalyst. Five series of heteroarenium catalysts were prepared and investigated: 1-Alkyl-3,5-dicyanopyridinium, 1-alkyl-3,5-dinitropyridinium, 1-alkyl-3-cyanopyrazinium, 1-alkyl-4-cyanopyrimidinium and 1-alkyl-4-(trifluoromethyl)pyrimidinium triflates (alkyl=butyl, hexyl, octyl, decyl, dodecyl and hexadecyl). Among them, the 1-octyl-3,5-dinitropyridinium and 1-decyl-4-(trifluoromethyl)pyrimidinium triflates were found to be superior catalysts, showing the best stability and the highest catalytic activity, achieving acceleration by a factor of 350 relative to the non-catalyzed reaction. In contrast to other organocatalytic two-phase oxidations that use hydrogen peroxide, the presented method is characterized by high chemoselectivity and low catalyst loading (5 mol%) and with the reactions being performed under mild conditions, i.e., at 25° using diluted hydrogen peroxide and a non-basic aqueous phase. The catalysts have simple structures and are readily available from com. materials. Practical applications are demonstrated via the oxidation of several types of sulfides and amines.

In some applications, this compound(1195-58-0)Application of 1195-58-0 is unique.If you want to know more details about this compound, you can contact with the author or consult more relevant literature.

Reference:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Most of the compounds have physiologically active properties, and their biological properties are often attributed to the heteroatoms contained in their molecules, and most of these heteroatoms also appear in cyclic structures. A Journal, Article, Research Support, Non-U.S. Gov’t, Journal of Developmental Physiology called Decrease in intestinal permeability to polyethylene glycol 1000 during development in the pig, Author is Westroem, B. R.; Tagesson, C.; Leandersson, P.; Folkesson, H. G.; Svendsen, J., which mentions a compound: 7661-33-8, SMILESS is O=C1N(C2=CC=C(Cl)C=C2)CCC1, Molecular C10H10ClNO, Reference of 1-(4-Chlorophenyl)pyrrolidin-2-one.

Changes in intestinal permeability during postnatal development in the pig were investigated by using different-sized polyethylene glycols (PEGs) in the Mr 766-1338 range (PEG 1000) as permeability probes. Pigs of varying age, newborn (0 h), 36-45 h old, and 22-28 days old, were gavage-fed PEG 1000 together with the macromol. markers bovine serum albumin, ovalbumin, or FITC-labeled dextran 70,000. The 4-h blood serum concentrations of the different markers were determined and taken as an estimate of their intestinal transmission. In the newborn pigs, high serum levels of PEGs were obtained, concomitant with high serum levels of bovine serum albumin and FITC-dextran. After intestinal macromol. closure in the 36-45 h-old pigs, lower serum PEG levels were found, especially of those with a Mr > 1100 Da. In the 22-28 day-old pigs, PEG levels were reduced to ≤10% of those in the 36-45-h-old pigs, with the levels decreasing markedly with increasing mol. size. These results show that there is a correlation between the intestinal permeability of PEGs, especially those >1100 Da, and macromols. in the newborn pig around intestinal closure, suggesting that such PEGs traverse the gut by the macromol. route. During later development, further intestinal maturation results in a markedly reduced permeability to PEG 1000.

In some applications, this compound(7661-33-8)Reference of 1-(4-Chlorophenyl)pyrrolidin-2-one is unique.If you want to know more details about this compound, you can contact with the author or consult more relevant literature.

Reference:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Safety of 1-(4-Chlorophenyl)pyrrolidin-2-one. So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic. Compound: 1-(4-Chlorophenyl)pyrrolidin-2-one, is researched, Molecular C10H10ClNO, CAS is 7661-33-8, about Ruthenium-catalyzed synthesis of N-substituted lactams by acceptorless dehydrogenative coupling of diols with primary amines.

The first example of synthesis of N-substituted lactams I (R = Ph, 4-(propan-2-yl)phenyl, 2H-1,3-benzodioxol-5-yl, naphthalen-2-yl, etc.; n = 1,2,3) and N-(p-tolyl)isoindolin-2-one via an acceptorless dehydrogenative coupling of diols HO(CH2)2(CH2)nCH2OH and [2-(hydroxymethyl)phenyl]methanol with primary amines RNH2 in one step, which was enabled by combining Ru3(CO)12 with a hybrid N-heterocyclic carbene-phosphine-phosphine ligand as the catalyst have been reported.

In some applications, this compound(7661-33-8)Safety of 1-(4-Chlorophenyl)pyrrolidin-2-one is unique.If you want to know more details about this compound, you can contact with the author or consult more relevant literature.

Reference:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

The reaction of an aromatic heterocycle with a proton is called a protonation. One of articles about this theory is 《Reaction of Grignard reagent with 3,5-dicyanopyridines》. Authors are Lukes, R.; Kuthan, J..The article about the compound:Pyridine-3,5-dicarbonitrilecas:1195-58-0,SMILESS:N#CC1=CC(C#N)=CN=C1).Related Products of 1195-58-0. Through the article, more information about this compound (cas:1195-58-0) is conveyed.

Et2O solutions of 3,5-dicyanopyridines reacted at 20-40° with MeMgI (Ia) or EtMgBr (Ib) in 4-6-fold excess to form NH.CR1:C(CN).CR2:C(CN).CHR3 or NH.CR1:C(CN).CHR2.C(CN):CR3. The following were prepared: R1 = R2 = R3 = H (I); R1 = R2 = H, R3 = Me (II); R1 = R3 = H, R2 = Et (III); R1 = Me, R2 = R3 = H (IV); R1 = R3 = Me, R3 = H (V); R1 = R3 = Me, R2 = H (VI); R1 = H, R2 = R3 = Me (VII); R1 = H, R2 = Me, R3 = Et (VIII); R1 = H, R2 = Et, R3 = Me (IX); R1 = R3 = Me, R2 = H (X); R1 = R2 = R3 = Me (XI); R1 = R2 = H, R3 = Me (XII); R1 = R3 = H, R2 = Et (XIII); R1 = R2 = Me, R3 = H (XIV); R1 = R2 = R3 = Me (XV). I with Ia gave 76% XII, I with Ib 65% XIII, II with Ia 66% VII, II with Ib 48% VIII, III with Ia 89% IX, IV with Ia about 43% X and XIV, V with Ia 82% XI, VI with Ia 35% XV.

In some applications, this compound(1195-58-0)Related Products of 1195-58-0 is unique.If you want to know more details about this compound, you can contact with the author or consult more relevant literature.

Reference:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Most of the compounds have physiologically active properties, and their biological properties are often attributed to the heteroatoms contained in their molecules, and most of these heteroatoms also appear in cyclic structures. A Journal, Canadian Journal of Chemistry called Photochemistry of matrix-isolated 5-cyano-2H-pyran-2-one (δ-cyano-α-pyrone) and cyanocyclobuta-1,3-diene, Author is Menke, Jessica L.; McMahon, Robert J., which mentions a compound: 1195-58-0, SMILESS is N#CC1=CC(C#N)=CN=C1, Molecular C7H3N3, Product Details of 1195-58-0.

Matrix-isolation photochem. (λ > 299 nm; Ar, 10 K) of 5-cyano-2H-pyran-2-one (5, δ-cyano-α-pyrone) shows complete conversion to a mixture of several ring-opened ketene isomers (6) and a ring-closed Dewar lactone (7), as detected by IR spectroscopy. Subsequent irradiation (λ > 200 nm) causes decarboxylation of the Dewar lactone (7) to produce cyanocyclobuta-1,3-diene (8). Continued irradiation (λ > 200 nm) results in the photodecomposition of cyanocyclobuta-1,3-diene (8) to cyanoacetylene and acetylene. 4-Cyanopyridine (10) was explored as an alternative photochem. precursor to cyanocyclobuta-1,3-diene (8). It was found, however, that 10 does not exhibit observable photochem. under our irradiation conditions.

When you point to this article, it is believed that you are also very interested in this compound(1195-58-0)Product Details of 1195-58-0 and due to space limitations, I can only present the most important information.

Reference:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: Pyridine-3,5-dicarbonitrile( cas:1195-58-0 ) is researched.Computed Properties of C7H3N3.Menke, Jessica L.; McMahon, Robert J. published the article 《Photochemistry of matrix-isolated 5-cyano-2H-pyran-2-one (δ-cyano-α-pyrone) and cyanocyclobuta-1,3-diene》 about this compound( cas:1195-58-0 ) in Canadian Journal of Chemistry. Keywords: photochem matrix isolated cyanopyranone; Dewar lactone produces cyanocyclobutadiene. Let’s learn more about this compound (cas:1195-58-0).

Matrix-isolation photochem. (λ > 299 nm; Ar, 10 K) of 5-cyano-2H-pyran-2-one (5, δ-cyano-α-pyrone) shows complete conversion to a mixture of several ring-opened ketene isomers (6) and a ring-closed Dewar lactone (7), as detected by IR spectroscopy. Subsequent irradiation (λ > 200 nm) causes decarboxylation of the Dewar lactone (7) to produce cyanocyclobuta-1,3-diene (8). Continued irradiation (λ > 200 nm) results in the photodecomposition of cyanocyclobuta-1,3-diene (8) to cyanoacetylene and acetylene. 4-Cyanopyridine (10) was explored as an alternative photochem. precursor to cyanocyclobuta-1,3-diene (8). It was found, however, that 10 does not exhibit observable photochem. under our irradiation conditions.

When you point to this article, it is believed that you are also very interested in this compound(1195-58-0)Computed Properties of C7H3N3 and due to space limitations, I can only present the most important information.

Reference:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Virtanen, P. Olavi I.; Ruostesuo, Pirkko; Ruostesuo, Pirkko published an article about the compound: 1-(4-Chlorophenyl)pyrrolidin-2-one( cas:7661-33-8,SMILESS:O=C1N(C2=CC=C(Cl)C=C2)CCC1 ).Reference of 1-(4-Chlorophenyl)pyrrolidin-2-one. Aromatic heterocyclic compounds can be classified according to the number of heteroatoms or the size of the ring. The authors also want to convey more information about this compound (cas:7661-33-8) through the article.

The dipole moments of 1-phenyl-2-pyrrolidone and its 2′-methyl, 3′-methyl, 4′-methyl, 2′-chloro, 3′-chloro, 4′-chloro, 2′-methoxy, 3′-methoxy, and 4′-methoxy derivatives were measured in dioxane at 30° and the dipole moments of the 1st 4 compounds also in cyclohexane at 30°. The dipole moments were larger in dioxane than in cyclohexane. The dipole moments of all the compounds except 1-(3-methoxyphenyl)-2-pyrrolidone and 1-(4-methoxyphenyl)-2-pyrrolidone agree with the values calculated by applying Eyring’s treatment and assuming free rotation of the pyrrolidonyl group about the bond joining it to the aromatic ring.

In some applications, this compound(7661-33-8)Reference of 1-(4-Chlorophenyl)pyrrolidin-2-one is unique.If you want to know more details about this compound, you can contact with the author or consult more relevant literature.

Reference:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts