Tag: M.W=100-150

Recently I am researching about MANNOSE-BINDING LECTIN; IMMUNE COMPONENT FICOLIN-3; ALL-CAUSE MORTALITY; VASCULAR COMPLICATIONS; COMPLEMENT; ASSOCIATION; MICROALBUMINURIA; POPULATION; DEFICIENCY; SEVERITY, Saw an article supported by the Danish Diabetes Association; Danish Council for Independent ResearchDet Frie Forskningsrad (DFF); Health Research Fund of Central Denmark Region; Folkhalsan Research Foundation; Academy of FinlandAcademy of FinlandEuropean Commission [316664, 299200]; Wilhelm and Else Stockmann Foundation; Novo Nordisk FoundationNovo Nordisk Foundation [OC0013659]; Paivikki and Sakari Sohlberg Foundation; Medical Society of Finland; Finnish Diabetes Research Foundation; Finnish Foundation for Cardiovascular Research; Karl Walter and Jarl Walter Perklen Foundation; Dorothea Olivia; HUH state research funding (EVO governmental grant) [TYH2018207]; Liv och Halsa Society. Published in NATURE RESEARCH in BERLIN ,Authors: Ostergaard, JA; Sigfrids, FJ; Forsblom, C; Dahlstrom, EH; Thorn, LM; Harjutsalo, V; Flyvbjerg, A; Thiel, S; Hansen, TK; Groop, PH. The CAS is 105-13-5. Through research, I have a further understanding and discovery of (4-Methoxyphenyl)methanol. Recommanded Product: 105-13-5

H-ficolin recognizes patterns on microorganisms and stressed cells and can activate the lectin pathway of the complement system. We aimed to assess H-ficolin in relation to the progression of diabetic kidney disease (DKD), all-cause mortality, diabetes-related mortality, and cardiovascular events. Event rates per 10-unit H-ficolin-increase were compared in an observational follow-up of 2,410 individuals with type 1 diabetes from the FinnDiane Study. DKD progression occurred in 400 individuals. The unadjusted hazard ratio (HR) for progression was 1.29 (1.18-1.40) and 1.16 (1.05-1.29) after adjustment for diabetes duration, sex, HbA(1c), systolic blood pressure, and smoking status. After adding triglycerides to the model, the HR decreased to 1.07 (0.97-1.18). In all, 486 individuals died, including 268 deaths of cardiovascular causes and 192 deaths of complications to diabetes. HRs for all-cause mortality and cardiovascular mortality were 1.13 (1.04-1.22) and 1.05 (0.93-1.17), respectively, in unadjusted analyses. These estimates lost statistical significance in adjusted models. However, the unadjusted HR for diabetes-related mortality was 1.19 (1.05-1.35) and 1.18 (1.02-1.37) with the most stringent adjustment level. Our results, therefore, indicate that H-ficolin predicts diabetes-related mortality, but neither all-cause mortality nor fatal/non-fatal cardiovascular events. Furthermore, H-ficolin is associated with DKD progression, however, not independently of the fully adjusted model.

Recommanded Product: 105-13-5. About (4-Methoxyphenyl)methanol, If you have any questions, you can contact Ostergaard, JA; Sigfrids, FJ; Forsblom, C; Dahlstrom, EH; Thorn, LM; Harjutsalo, V; Flyvbjerg, A; Thiel, S; Hansen, TK; Groop, PH or concate me.

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In 2021 J CHEM TECHNOL BIOT published article about AROMATIC ALCOHOLS; MULTICOMPONENT SYNTHESIS; TIO2 NANOPARTICLES; AEROBIC OXIDATION; TITANIUM-DIOXIDE; IONIC LIQUIDS; METAL-OXIDES; EFFICIENT; ALDEHYDES; DEGRADATION in [Taghavi, Shaghayegh; Amoozadeh, Ali; Nemati, Firouzeh] Semnan Univ, Fac Chem, Dept Organ Chem, Semnan 3513119111, Iran in 2021, Cited 76. The Name is (4-Methoxyphenyl)methanol. Through research, I have a further understanding and discovery of 105-13-5. Recommanded Product: 105-13-5

BACKGROUND Deep eutectic solvents (DESs) are prepared by mixing solid organic precursors to form a liquid driven from strong hydrogen-bond interactions. The physical and chemical properties of these compounds have been widely investigated, and it has been shown that they are benign media for biotransformations, organicsynthesis, biodieselpreparation, and a sustainable media for nanoscale and functional materials. RESULTS This study is the first report on the synthesis of n-TiO2-P25@TDI@DES (urea: ZnCl2) with photo catalytic activity. This nano photocatalyst was obtained through covalent grafting of TiO2-P25 nanoparticles to an inexpensive and highly reactive linker (2,4-toluene diisocyanate). The presented nano photocatalyst has been employed as a covalently grafted Lewis acidic deep eutectic solvent to oxidize various primary benzyl alcohols to their corresponding carbonyl compounds by sodium nitrate as oxidant, under visible light exposure. CONCLUSION This highly efficient nanocatalyst was investigated by various characterization techniques including fourier transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD), thermogravimetric analysis (TGA), scanning electron microscopy equipped with energy-dispersive X-ray spectroscopy (SEM with EDX), and elemental analysis. Owing to its enhanced catalytic activity, thermal stability, and environmentally friendly nature, the present method can be regarded as an attractive green chemistry approach. (c) 2020 Society of Chemical Industry (SCI)

About (4-Methoxyphenyl)methanol, If you have any questions, you can contact Taghavi, S; Amoozadeh, A; Nemati, F or concate me.. Recommanded Product: 105-13-5

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In 2021 CANCER MANAG RES published article about GROWTH-FACTOR RECEPTOR; 1ST-LINE TREATMENT; BRAIN METASTASES; OPEN-LABEL; PHASE-II; RESISTANCE; CHEMOTHERAPY; GEFITINIB; ERLOTINIB; MULTICENTER in [Peng, Da; Dai, Chengcheng; Wang, Zifan; Huang, Ziyi; Peng, Rui; Ma, Xuezhen] Qingdao Univ, Affiliated Qingdao Cent Hosp, Dept Oncol, 127 Siliunan Rd, Qingdao 266042, Shandong, Peoples R China; [Shan, Dongfeng] Qingdao Univ, Affiliated Hosp, Qingdao, Shandong, Peoples R China; [Li, Jie] Jiaozhou Cent Hosp, Dept Oncol, Jiaozhou, Peoples R China; [Zhao, Peng] Qingdao Univ, Affiliated Qingdao Cent Hosp, Biotherapy Ctr, Qingdao, Shandong, Peoples R China in 2021, Cited 25. The Name is (4-Methoxyphenyl)methanol. Through research, I have a further understanding and discovery of 105-13-5. Quality Control of (4-Methoxyphenyl)methanol

Purpose: As a third-generation EGFR TKI has been taken orally, Osimertinib effectively inhibits mutant EGFR, including T790M EGFR resistance mutations. Here, we examined real-world efficacy and tolerability of Osimertinib among Chinese patients with advanced EGFR T790M-mutant NSCLC. Patients and Methods: A total of 106 advanced NSCLC patients who were taking Osimertinib following disease progression after EGFR-TKIs or other treatments were retro-spectively recruited in this study. The PFS and OS after Osimertinib treatment were analyzed as the primary endpoints. Results: Osimertinib was used as a second line and >= 3rd line treatment in 22.6% and 77.4% of the patients, respectively. DCR and ORR were 93.4% and 57.5%, respectively. Median PFS was 12.4 12 (95% CI, 10.5-13.5) months. The PFS was 11 (8.0, 14.0) and 12 (10.3,13.7) months (p = 0.373), in patients with and without CNS metastasis, respectively. PFS in 2nd and >= 3rd line treatment was 11 (9.0, 13.0) and 12.4 12 (8.9, 15.1) months (p = 0.799), respectively. In patients with EGFR exon 19 deletion and exon 21 L858 mutation, the median PFS was 11 (9.2, 12.8) and 12 (9.2, 14.8) months, respectively (p = 0.833). Median PFS in the monotherapy group and combined anti-angiogenesis group was 11 (9.9,12.1) and 14 (11.2,16.8) months, respectively. Median OS after Osimertinib initiation was 27 (19.6, 34.4) months: 15 (6.9, 23.1) and 27 (22, 32) months in patients with and without CNS metastasis (p=0.027), 27 (20.3,33.7) months and (undefined) as second line or >= 3rd line of treatment (p = 0.421), respectively. In patients with exon 19 deletion, the median OS was not reached, and in patients with exon 21 L858 mutations, the median OS was 23 (19.1,29.9) months (p=0.027). Median OS in the monotherapy group was 27 (21.7,32.3) months, and in combined anti-angiogenesis group was not reached (p=0.68). Conclusion: Osimertinib can effectively treat advanced NSCLC with T790M mutations independently of previous treatment lines.

Quality Control of (4-Methoxyphenyl)methanol. About (4-Methoxyphenyl)methanol, If you have any questions, you can contact Peng, D; Shan, DF; Dai, CC; Li, J; Wang, ZF; Huang, ZY; Peng, R; Zhao, P; Ma, XZ or concate me.

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An article Cross beta-alkylation of primary alcohols catalysed by DMF-stabilized iridium nanoparticles WOS:000627441700007 published article about N,N-DIMETHYLFORMAMIDE-STABILIZED PALLADIUM NANOCLUSTERS; ALPHA-ALKYLATION; BORROWING HYDROGEN; GUERBET REACTION; N-BUTANOL; METHYLATION; KETONES; METHANOL; DIMETHYLFORMAMIDE; ALPHA,OMEGA-DIOLS in [Kobayashi, Masaki; Yamaguchi, Hiroki; Obora, Yasushi] Kansai Univ, Fac Chem Mat & Bioengn, Dept Chem & Mat Engn, Suita, Osaka 5648680, Japan; [Suzuki, Takeyuki] Osaka Univ, Comprehens Anal Ctr, Inst Sci & Ind Res ISIR, 8-1 Mihogaoka, Ibaraki, Osaka 5670057, Japan in 2021, Cited 64. The Name is (4-Methoxyphenyl)methanol. Through research, I have a further understanding and discovery of 105-13-5. Application In Synthesis of (4-Methoxyphenyl)methanol

A simple method for the cross beta-alkylation of linear alcohols with benzyl alcohols in the presence of DMF-stabilized iridium nanoparticles was developed. The nanoparticles were prepared in one-step and thoroughly characterized. Furthermore, the optimum reaction conditions have a wide substrate scope and excellent product selectivity.

Application In Synthesis of (4-Methoxyphenyl)methanol. About (4-Methoxyphenyl)methanol, If you have any questions, you can contact Kobayashi, M; Yamaguchi, H; Suzuki, T; Obora, Y or concate me.

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In 2021 CATAL LETT published article about METAL-ORGANIC FRAMEWORK; SELECTIVE OXIDATION; AROMATIC ALCOHOLS; HYDROGEN-PRODUCTION; REACTIVE DYE; NANOCOMPOSITE; EFFICIENT; MIL-101; NANOPARTICLES; PERFORMANCE in [Wang, Mingming; Ma, Yali; Lv, Bolin; Hua, Fenglin; Meng, Shuangyan; Lei, Xuedi; Wang, Qingtao; Su, Bitao; Lei, Ziqiang; Yang, Zhiwang] Northwest Normal Univ, Coll Chem & Chem Engn, Key Lab Polymer Mat Gansu Prov, Key Lab Ecofunct Polymer Mat,Minist Educ, Lanzhou 730070, Peoples R China in 2021, Cited 44. The Name is (4-Methoxyphenyl)methanol. Through research, I have a further understanding and discovery of 105-13-5. Safety of (4-Methoxyphenyl)methanol

A novel photoactive porous material of GR/FeMIL-101 based on FeMIL-101 metal organic frameworks (MOFs) was successfully synthesized via a simple hydrothermal method. The structural and photoelectric properties of the GR/FeMIL-101 was analyzed by XRD, SEM, TEM, TGA, XPS, UV-vis DRS, FT-IR, PL and EIS methods. The photocatalytic performance for the selective oxidation of benzyl alcohol with GR/FeMIL-101 as catalysts was evaluated under visible light irradiation. The results showed that the GR/FeMIL-101 nanohybrid had better photocatalytic performance than both of FeMIL-101 and the pristine MIL-101. It was further found that the incorporation of Fe and MIL-101 caused valence fluctuations of Fe3+/Fe2+ which improved the absorption of visible-light and increased the separation efficiency of photogenerated charges. In addition, the combination of FeMIL-101 and GR could further promote the transfer rate of the photoelectrons. The mechanism of the reaction revealed that center dot O-2(-) was the dominating active specie in this reaction through active species trapping experiments. [GRAPHICS] .

Safety of (4-Methoxyphenyl)methanol. About (4-Methoxyphenyl)methanol, If you have any questions, you can contact Wang, MM; Ma, YL; Lv, BL; Hua, FL; Meng, SY; Lei, XD; Wang, QT; Su, BT; Lei, ZQ; Yang, ZW or concate me.

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An article Application of deep eutectic solvent and SWCNT-ZrO2 nanocomposite as conductive mediators for the fabrication of simple and rapid electrochemical sensor for determination of trace anti-migration drugs WOS:000647794500010 published article about CARBON-PASTE ELECTRODE; SOLID-PHASE EXTRACTION; VOLTAMMETRIC SENSOR; GRAPHENE OXIDE; RIZATRIPTAN BENZOATE; GLUCOSE SENSOR; ASCORBIC-ACID; MIGRAINE; TRIPTANS; ACETAMINOPHEN in [Bavandpour, Razieh; Rajabi, Maryam; Asghari, Alireza] Semnan Univ, Dept Chem, Semnan 35195363, Iran; [Karimi-Maleh, Hassan] Univ Elect Sci & Technol China, Sch Resources & Environm, POB 611731,Xiyuan Ave, Chengdu, Peoples R China; [Karimi-Maleh, Hassan] Quchan Univ Technol, Dept Chem Engn, Quchan, Iran; [Karimi-Maleh, Hassan] Univ Johannesburg, Dept Chem Sci, POB 17011,Doornfontein Campus, ZA-2028 Johannesburg, South Africa in 2021, Cited 73. The Name is (4-Methoxyphenyl)methanol. Through research, I have a further understanding and discovery of 105-13-5. Name: (4-Methoxyphenyl)methanol

In this study, a green deep eutectic solvent (DES) was synthesized at room temperature-based choline chloride (ChCl) and 4-methoxybenzyl alcohol (Anisyl alcohol (An-OH)) used as the conductive binder for modification of carbon paste electrode (CPE). In addition, single wall carbon nanotubes decorated by ZrO2 (SWCNT-ZrO2) nanocomposite was synthesized by the hydrothermal method and characterized by field emission scanning electron microscopy (FE-SEM), energy dispersive spectroscopy (EDAX), and X-ray powder diffraction (XRD) analytical techniques. The DES and SWCNT-ZrO2 were used as a binder and modifier in the carbon paste electrode structure to form CPE/DES/SWCNT-ZrO2 as an electrochemical sensor for the simultaneous determination of paracetamol and rizatriptan as two anti-migration drugs for the first time. In the direction of optimal experimental conditions, the effective parameters such as pH, amount of modifier, and electrolyte type were optimized. Under these conditions, the limits of detection (LODs) 0.7 nM and 9.0 nM; linear dynamic ranges (LDRs) 0.003?100 and 0.08?100; and relative standard deviations (RSDs for n = 5) 1.63 and 1.52 were sequentially found for rizatriptan and paracetamol. The results indicate that the sensor can be applied for the detection of trace amounts of paracetamol and rizatriptan in clinical and pharmaceutical samples.

About (4-Methoxyphenyl)methanol, If you have any questions, you can contact Bavandpour, R; Rajabi, M; Karimi-Maleh, H; Asghari, A or concate me.. Name: (4-Methoxyphenyl)methanol

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In 2021 TETRAHEDRON LETT published article about TRANSITION-METAL-FREE; S BOND FORMATION; AMIDE SYNTHESIS; ONE-POT; AMINES; EFFICIENT; ALCOHOLS; ALPHA; NANOPARTICLES; PD in [Rerkrachaneekorn, Tanawat; Tankam, Theeranon; Sukwattanasinitt, Mongkol; Wacharasindhu, Sumrit] Chulalongkorn Univ, Fac Sci, Nanotec CU Ctr Excellence Food & Agr, Dept Chem, Bangkok 10330, Thailand; [Wacharasindhu, Sumrit] Chulalongkorn Univ, Fac Sci, Dept Chem, Green Chem Fine Chem Prod STAR, Bangkok 10330, Thailand in 2021, Cited 62. The Name is (4-Methoxyphenyl)methanol. Through research, I have a further understanding and discovery of 105-13-5. Computed Properties of C8H10O2

In this research, we have developed a mild electrochemical process for oxidative amidation of benzyl alcohols/aromatic aldehydes with cyclic amines into the corresponding benzamides. This electroorganic synthetic method proceeds using NaI as a redox mediator under ambient temperature in undivided cell, providing more than 25 examples of amide products in moderate to good yields. The benefits of this reaction include one-pot synthesis, open air condition, proceed in aqueous media and no requirement of external conducting salt, base and oxidant. (C) 2021 Elsevier Ltd. All rights reserved.

Computed Properties of C8H10O2. About (4-Methoxyphenyl)methanol, If you have any questions, you can contact Rerkrachaneekorn, T; Tankam, T; Sukwattanasinitt, M; Wacharasindhu, S or concate me.

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COA of Formula: C8H10O2. Recently I am researching about MCM-41 MOLECULAR-SIEVES; AROMATIC-AMINES; SILICA NANOPARTICLES; SOLVENT-FREE; OXIDATION; IRON; BENZYLATION; RUTHENIUM; AMINATION; SECONDARY, Saw an article supported by the Tarbiat Modares University; Iran National Science Foundation (INSF)Iran National Science Foundation (INSF) [96009299]. Published in WILEY in HOBOKEN ,Authors: Nasresfahani, Z; Kassaee, MZ. The CAS is 105-13-5. Through research, I have a further understanding and discovery of (4-Methoxyphenyl)methanol

A bimetallic catalyst (Ni/Cu-MCM-41) is prepared via co-condensation method. The latter is characterized by Fourier transform infrared (FT-IR), X-ray powder diffraction (XRD), scanning electron microscopy (SEM), energy dispersive X-ray spectroscopy (EDX), diffuse reflectance spectroscopy (DRS), and nitrogen adsorption-desorption analysis. Catalytic performance of Ni/Cu-MCM-41 is probed in N-alkylation of amines with alcohols through a hydrogen autotransfer process. Noteworthy, this catalytic system appears very efficient for synthesis of a range of secondary and tertiary amines in good to excellent isolated yields. Moreover, the catalyst is successfully recovered and reused four times without notable decrease in its activity.

COA of Formula: C8H10O2. About (4-Methoxyphenyl)methanol, If you have any questions, you can contact Nasresfahani, Z; Kassaee, MZ or concate me.

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Computed Properties of C8H10O2. Authors Xia, YY; Lv, QY; Yuan, H; Wang, JY in SPRINGER INTERNATIONAL PUBLISHING AG published article about in [Xia, Yu-Yan; Lv, Qing-Yang; Yuan, Hua; Wang, Jia-Yi] Wuhan Inst Technol, Minist Educ, Key Lab Green Chem Proc, Wuhan 430073, Peoples R China in 2021, Cited 46. The Name is (4-Methoxyphenyl)methanol. Through research, I have a further understanding and discovery of 105-13-5

An efficient method for catalyzing the ammoxidation of aromatic alcohols to aromatic nitriles was developed, in which a new heterogeneous catalyst based on transition metal elements was employed, the new catalyst was named Co-[Bmim]Br/C-700 and then characterized by X-ray photo-electronic spectroscopy, transmission electron microscope and X-ray diffraction. The reaction was carried out by two consecutive dehydrogenations under the catalysis of Co-[Bmim]Br/C-700, which catalytically oxidized the alcohol to the aldehyde, and then the aldehyde was subjected to ammoxidation to the nitrile. The catalyst system was suitable for a wide range of substrates and nitriles obtained in high yields, especially, the conversion rate of benzyl alcohol, 4-methoxybenzyl alcohol, 4-chlorobenzyl alcohol and 4-nitrobenzyl alcohol reached 100%. The substitution of ammonia and oxygen for toxic cyanide to participate in the reaction accords with the theory of green chemistry.

Computed Properties of C8H10O2. About (4-Methoxyphenyl)methanol, If you have any questions, you can contact Xia, YY; Lv, QY; Yuan, H; Wang, JY or concate me.

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Authors Lin, Q; Wang, WL; Yang, LP; Duan, XH in SPANDIDOS PUBL LTD published article about in [Yang, Liping; Duan, Xiaohua] Yunnan Univ Chinese Med, Yunnan Key Lab Dai & Yi Med, 1076 Yuhua Rd, Kunming 650500, Yunnan, Peoples R China; [Lin, Qing; Wang, Weili] Yunnan Univ Chinese Med, Dept Pharmacol, Kunming 650500, Yunnan, Peoples R China in 2021, Cited 40. Application In Synthesis of (4-Methoxyphenyl)methanol. The Name is (4-Methoxyphenyl)methanol. Through research, I have a further understanding and discovery of 105-13-5

Damage to the blood-brain barrier (BBB) during the process of cerebral ischemic injury is a key factor that affects the treatment of this condition. The present study aimed to assess the potential effects of 4-methoxybenzyl alcohol (4-MA) on brain microvascular endothelial cells (bEnd.3) against oxygen-glucose deprivation/reperfusion (OGD/Rep) using an in vitro model that mimics in vivo ischemia/reperfusion injury. In addition, the present study aimed to explore whether this underlying mechanism was associated with the inhibition of pro-inflammatory factors and the activation status of the PI3K/Akt signaling pathway. bEnd.3 cells were subjected to OGD/Rep-induced injury before being treated with 4-MA, following which cell viability, lactate dehydrogenase (LDH) release and levels of nitric oxidase (NO) were detected by colorimetry, pro-inflammatory factors including tumor necrosis factor-alpha (TNF-alpha), interleukin (IL)-1 beta and IL-6, were detected by ELISA. The expression levels of occluding and claudin-5were evaluated by immunofluorescence staining. The expression levels of AKT, phosphorylated (p)-Akt, endothelial nitric oxide synthase (eNOS) and p-eNOS were also measured by western blot analysis. After bEnd.3 cells were subjected to OGD/Rep-induced injury, cell viability and NO levels were significantly decreased, whilst LDH leakage and inflammatory factor (TNF-alpha, IL-1 beta and IL-6) levels were significantly increased. Treatment with 4-MA significantly ameliorated cell viability, LDH release and the levels of NO and pro-inflammatory factors TNF-alpha, IL-1 beta and IL-6 as a result of OGD/Rep. Furthermore, treatment with 4-MA upregulated the expression of occludin, claudin-5, Akt and eNOS, in addition to increasing eNOS and AKT phosphorylation in bEnd.3 cells. These results suggest that 4-MA can alleviate OGD/Rep-induced injury in bEnd.3 cells by inhibiting inflammation and by activating the PI3K/AKT signaling pathway as a possible mechanism. Therefore, 4-MA can serve as a potential candidate for treating OGD/Rep-induced injury.

About (4-Methoxyphenyl)methanol, If you have any questions, you can contact Lin, Q; Wang, WL; Yang, LP; Duan, XH or concate me.. Application In Synthesis of (4-Methoxyphenyl)methanol

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