Tag: M.W=100-150

Hight-Huf, Nicholas published the artcileStabilization of Three-Particle Excitations in Monolayer MoS2 by Fluorinated Methacrylate Polymers, Recommanded Product: n-Octanol, the main research area is molybdenum sulfide monolayer fluorinated methacrylate polymer trion stabilization.

While extrinsic factors, such as substrates and chem. doping, are known to strongly influence visible photoemission from monolayer MoS2, key fundamental knowledge for p-type polymeric dopants is lacking. We investigated perturbations to the electronic environment of 2D MoS2 using fluorinated polymer coatings and specifically studied stabilization of three-particle states by monitoring changes in intensities and emission maxima of three-particle and two-particle emissions. We calculated changes in carrier d. and trion binding energy, the latter having an addnl. contribution from MoS2 polarization by the polymer. Polarization is further suggested by Kelvin probe force microscopy (KPFM) measurements of large Fermi level shifts. Changes similar in magnitude, but opposite in sign, were observed in 2D MoS2 coated with an analogous nonfluorinated polymer. These findings highlight the important interplay between electron exchange and electrostatic interactions at the interface between polymers and transition metal dichalcogenides (TMDCs), which govern fundamental electronic properties relevant to next-generation devices.

Journal of Physical Chemistry Letters published new progress about Binding energy. 111-87-5 belongs to class alcohols-buliding-blocks, name is n-Octanol, and the molecular formula is C8H18O, Recommanded Product: n-Octanol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Khajone, Vijay B. published the artcileBronsted acid functionalized phthalocyanine on perylene diimide framework knotted with ionic liquid: An efficient photo-catalyst for production of biofuel component octyl levulinate at ambient conditions under visible light irradiation, Application of n-Octanol, the main research area is Bronsted acid functionalized phthalocyanine perylene diimide framework esterification; biofuel octyl levulinate visible light irradiation ionic liquid photocatalyst.

Novel Broensted acid functionalized phthalocyanine on perylene diimide framework knotted with ionic liquid (BAFPcPDIL) was synthesized and confirmed by instrumentation techniques. DRS-spectrum and Hammett value has been determined to confirm band-gap and proton levels of photo-catalyst, resp. The photo-catalytic performance was evaluated by production of octyl levulinate (OL) using levulinic acid (LA) with n-octyl alc. (OA) under visible light irradiations. Response surface methodol. (RSM) with Box-Behnken design (BBD) with 29 experiments was applied to explore consequences of 4 crucial process variables: catalyst loading (A), molar ratio of reactants (B) and power of visible light (C), duration in hour (D) on OL yield. From the model, the optimum conditions for the utmost conversion were found as: 10 mg catalyst with (1:1) alc. to LA molar ratio under 12 W lamp, in 12 h for completing esterification reaction with 95.58% yield of OL. With optimum conditions, various alkyl esters such as Me levulinate 92.14%, Et levulinate 93.12%, Pr levulinate 91.45%, isoPr levulinate 92.38%, Bu levulinate 85.13%, n-pentyl levulinate 86.35%, n-hexyl levulinate 89.57%, CMe3 levulinate 91.58%, were successfully synthesized with excellent yields. The plausible photocatalytic mechanism of the esterification reaction was also described. The study was extended on blending of OL with diesel sample in 10-30%, found comparable result of d., kinematic viscosity, calorific values, cetane number, flash, fire and pour point of the blended samples with blank diesel sample and appreciable changes in exhaust gases of 25% blended diesel sample. Addnl., BAFPcPDIL displayed good recyclability without loss of photo reactivity after 4 runs.

Fuel published new progress about Biodiesel fuel. 111-87-5 belongs to class alcohols-buliding-blocks, name is n-Octanol, and the molecular formula is C8H18O, Application of n-Octanol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Xuan, Tiemin published the artcileAn optical study on spray and combustion characteristics of ternary hydrogenated catalytic biodiesel/methanol/n-octanol blends; part I: Spray morphology, ignition delay, and flame lift-off length, Category: alcohols-buliding-blocks, the main research area is biodiesel methanol octanol blend spray morphol optical combustion.

A fundamental study on spray morphol., ignition delay, and flame lift-off length of two ternary hydrogenated catalytic biodiesel (HCB)/methanol/n-octanol blends were carried out by performing visualization tests through high-speed Schlieren and OH* chemiluminescence simultaneously within a quiescent combustion chamber. The two ternary mixtures are 68% by volume HCB, 17% octanol, and 15% methanol, as well as 58% HCB, 17% octanol, and 25% methanol, which are denoted as M15 and M25 resp. It was found that the mixture stability of HCB/methanol is significantly enhanced using n-octanol as the co-solvent. The pure HCB (M0) was also tested under the same operating conditions as references All the sprays were injected into the chamber through an injector equipped with a single-hole nozzle. Exptl. results show that spray of M0 presents a faster penetration, following by M15 and M25, which is mainly caused by the shorter ignition delay of M0; With the increase of methanol percentage in the blends, the stoichiometric fuel mass fraction increases because of the high oxygen content of methanol, which contributes to a longer ignition delay; There are two factors of the blended fuel properties affecting flame lift-off length, namely stoichiometric fuel mass fraction and cetane number It was found the cetane number plays a much more important role than that of stoichiometric fuel mass fraction on lift-off length.

Fuel published new progress about Biodiesel fuel. 111-87-5 belongs to class alcohols-buliding-blocks, name is n-Octanol, and the molecular formula is C8H18O, Category: alcohols-buliding-blocks.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Sidharth published the artcileComparison of properties of ternary fuel blends of diesel-octanol with biodiesel, COA of Formula: C8H18O, the main research area is biodiesel octanol nitrogen oxide transesterification petroleum diesel.

Biodiesel is adopted by many countries as a substitute to diesel and is used in blended form in a diesel engine. It has very similar properties to diesel. However, owing to slightly higher viscosity, d. and nitrogen oxide (NOX) emissions on burning, it still is not the best choice. Octanol, have similar properties to diesel. Octanol has added oxygen and also reduces the NOX emissions due to the quenching effect in the cylinder. However, its lower calorific value shall reduce engine performance. In the current study, waste cooking oil biodiesel is produced by a single step transesterification process and several blends of diesel, biodiesel and octanol were prepared Fourier-transform IR spectroscopy (FTIR) and oxidation stability tests of the produced biodiesel were performed. FTIR test confirmed the presence of biodiesel. Oxidation stability test of biodiesel was also passed as the induction time in over 6 h. Blends of diesel and octanol were prepared in proportion of diesel (95%, 90%, 85% and 80%) and octanol (5%, 10%, 15% and 20%). These blends were added to 3%, 5% and 10% biodiesel. Several physico-chem. properties namely d., viscosity, calorific value, flash point and cold filter plugging point (CFPP) were determined as per ASTM standards It is concluded that the 10% octanol, 90% diesel when mixed with 10% biodiesel showed very similar properties to diesel and shall be a viable alternative to petroleum diesel.

IOP Conference Series: Materials Science and Engineering published new progress about Biodiesel fuel. 111-87-5 belongs to class alcohols-buliding-blocks, name is n-Octanol, and the molecular formula is C8H18O, COA of Formula: C8H18O.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Zarini, Daniele published the artcileAre In Silico Approaches Applicable As a First Step for the Prediction of e-Liquid Toxicity in e-Cigarettes?, Category: alcohols-buliding-blocks, the main research area is toxicity electronic cigarette liquid QSAR model.

Recent studies have raised concerns about e-cigarette liquid inhalation toxicity by reporting the presence of chems. with European Union CLP toxicity classification. In this scenario, the regulatory context is still developing and is not yet up to date with vaping current reality. Due to the paucity of toxicol. studies, robust data regarding which components in tent. In this study we applied computational methods for studied chems. as a useful tool for predicting the acute toxicity of chems. contained in e-liquids The purpose of t the potential health concerns associated with e-liquid ingredients, (b) to prioritize e-liquid ingredients by calculating the e-tox index, and (c) to estimate acute toxicity of e-liquid mixtures QSAR models were generated using QSARINS software to fill the acute toxicity data gap of 264 e-liquid ingredients. As a second step, the potential acute toxicity of e-liquids mixtures was evaluated. Our preliminary data suggest that a computational approa serve as a roadmap to enable regulatory bodies to better regulate e-liquid composition and to contribute to consumer health protection.

Chemical Research in Toxicology published new progress about Acute toxicity. 505-10-2 belongs to class alcohols-buliding-blocks, name is 3-(Methylthio)propan-1-ol, and the molecular formula is C4H10OS, Category: alcohols-buliding-blocks.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

MacCannell, Amanda D. V. published the artcileSexual dimorphism in adipose tissue mitochondrial function and metabolic flexibility in obesity, Safety of (S)-2-hydroxysuccinic acid, the main research area is gene expression sexual dimorphism adipose tissue metabolic flexibility obesity.

The prevalence of obesity is growing globally. Adiposity increases the risk for metabolic syndrome, type 2 diabetes and cardiovascular disease. Adipose tissue distribution influences systemic metabolism and impacts metabolic disease risk. The link between sexual dimorphisms of adiposity and metabolism is poorly defined. We hypothesise that depot-specific adipose tissue mitochondrial function contributes to the sexual dimorphism of metabolic flexibility in obesity. Male and female mice fed high fat diet (HFD) or standard diet (STD) from 8-18 wk of age underwent whole animal calorimetry and high-resolution mitochondrial respirometry anal. on adipose tissue depots. To determine translatability we used RT-qPCR to examine key brown adipocyte-associated gene expression: peroxisome proliferator-activated receptor co-activator 1α, Uncoupling protein 1 and cell death inducing DFFA like effector a in brown adipose tissue (BAT) and s.c. adipose tissue (sWAT) of 18-wk-old mice and sWAT from human volunteers. Male mice exhibited greater weight gain compared to female mice when challenged with HFD. Relative to increased body mass, the adipose to body weight ratio for BAT and sWAT depots was increased in HFD-fed males compared to female HFD-fed mice. Oxygen consumption, energy expenditure, respiratory exchange ratio and food consumption did not differ between males and females fed HFD. BAT mitochondria from obese females showed increased Complex I & II respiration and maximal respiration compared to lean females whereas obese males did not exhibit adaptive mitochondrial BAT respiration. Sexual dimorphism in BAT-associated gene expression in sWAT was also associated with Body Mass Index in humans. We show that sexual dimorphism of weight gain is reflected in mitochondrial respiration anal. Female mice have increased metabolic flexibility to adapt to changes in energy intake by regulating energy expenditure through increased complex II and maximal mitochondrial respiration within BAT when HFD challenged and increased proton leak in sWAT mitochondria.

International Journal of Obesity published new progress about Adipose tissue. 97-67-6 belongs to class alcohols-buliding-blocks, name is (S)-2-hydroxysuccinic acid, and the molecular formula is C4H6O5, Safety of (S)-2-hydroxysuccinic acid.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Simmen, Frank A. published the artcileMalic enzyme 1 (ME1) in the biology of cancer: it is not just intermediary metabolism, Safety of (S)-2-hydroxysuccinic acid, the main research area is review malic enzyme cancer biol intermediary metabolism; NADPH; cancer; glutathione; hyperinsulinemia; malic enzyme; thioredoxin.

Malic enzyme 1 (ME1) is a cytosolic protein that catalyzes the conversion of malate to pyruvate while concomitantly generating NADPH from NADP. Early studies identified ME1 as a mediator of intermediary metabolism primarily through its participatory roles in lipid and cholesterol biosynthesis. ME1 was one of the first identified insulin-regulated genes in liver and adipose and is a transcriptional target of thyroxine. Multiple studies have since documented that ME1 is pro-oncogenic in numerous epithelial cancers. In tumor cells, the reduction of ME1 gene expression or the inhibition of its activity resulted in decreases in proliferation, epithelial-to-mesenchymal transition and in vitro migration, and conversely, in promotion of oxidative stress, apoptosis and/or cellular senescence. Here, we integrate recent findings to highlight ME1’s role in oncogenesis, provide a rationale for its nexus with metabolic syndrome and diabetes, and raise the prospects of targeting the cytosolic NADPH network to improve therapeutic approaches against multiple cancers.

Journal of Molecular Endocrinology published new progress about Adipose tissue. 97-67-6 belongs to class alcohols-buliding-blocks, name is (S)-2-hydroxysuccinic acid, and the molecular formula is C4H6O5, Safety of (S)-2-hydroxysuccinic acid.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Bikman, Benjamin T. published the artcileA high-carbohydrate diet lowers the rate of adipose tissue mitochondrial respiration, Synthetic Route of 97-67-6, the main research area is adipose tissue mitochondrial respiration diet rate.

Adipocyte mitochondrial respiration may influence metabolic fuel partitioning into oxidation vs. storage, with implications for whole-body energy expenditure. Although insulin has been shown to influence mitochondrial respiration, the effects of dietary macronutrient composition have not been well characterized. The aim of this exploratory study was to test the hypothesis that a high-carbohydrate diet lowers the oxygen flux of adipocyte mitochondria ex vivo. Among participants in a randomized-controlled weight-loss maintenance feeding trial, those consuming a high-carbohydrate diet (60% carbohydrate as a proportion of total energy, n = 10) had lower rates of maximal adipose tissue mitochondrial respiration than those consuming a moderate-carbohydrate diet (40%, n = 8, p = 0.039) or a low-carbohydrate diet (20%, n = 9, p = 0.005) after 10 to 15 wk. This preliminary finding may provide a mechanism for postulated calorie-independent effects of dietary composition on energy expenditure and fat deposition, potentially through the actions of insulin on fuel partitioning.

European Journal of Clinical Nutrition published new progress about Adipose tissue. 97-67-6 belongs to class alcohols-buliding-blocks, name is (S)-2-hydroxysuccinic acid, and the molecular formula is C4H6O5, Synthetic Route of 97-67-6.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Camarena-Pozos, David A. published the artcileSmells from the desert: Microbial volatiles that affect plant growth and development of native and non-native plant species, Safety of 3-(Methylthio)propan-1-ol, the main research area is Arabidopsis Nicotiana plant growth microbial volatile; agaves; arid environments; cacti; microbial organic volatile compounds; plant growth; plant microbiome; plant-microbe interactions.

The plant microbiota can affect host fitness via the emission of microbial volatile organic compounds (mVOCs) that influence growth and development. However, evidence of these mols. and their effects in plants from arid ecosystems is limited. We screened the mVOCs produced by 40 core and representative members of the microbiome of agaves and cacti in their interaction with Arabidopsis thaliana and Nicotiana benthamiana. We used SPME-GC-MS to characterize the chem. diversity of mVOCs and tested the effects of selected compounds on growth and development of model and host plants. Our study revealed that approx. 90% of the bacterial strains promoted plant growth both in A. thaliana and N. benthamiana. Bacterial VOCs were mainly composed of esters, alcs., and S-containing compounds with 25% of them not previously characterized. Remarkably, Et isovalerate, isoamyl acetate, 3-methyl-1-butanol, benzyl alc., 2-phenylethyl alc., and 3-(methylthio)-1-propanol, and some of their mixtures, displayed beneficial effects in A. thaliana and also improved growth and development of Agave tequilana and Agave salmiana in just 60 days. Volatiles produced by bacteria isolated from agaves and cacti are promising mols. for the sustainable production of crops in arid and semi-arid regions.

Plant, Cell & Environment published new progress about Agave salmiana. 505-10-2 belongs to class alcohols-buliding-blocks, name is 3-(Methylthio)propan-1-ol, and the molecular formula is C4H10OS, Safety of 3-(Methylthio)propan-1-ol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Hansen, Moritz E. published the artcileTotal synthesis of mutanobactins A, B from the human microbiome: Macrocyclization and thiazepanone assembly in a single step, Related Products of alcohols-buliding-blocks, the main research area is mutanobactin total synthesis human microbiome lipopeptide; aspartate substitution reduction Mutsunobu displacement phthalimide methanolysis cyclization; peptide coupling solid phase synthesis macrocyclization thiazepanone assembly; cyclization mechanism dehydration aldol addition; Cyclization; Macrocycles; Peptide Synthesis; Total Synthesis.

We report the first total syntheses of tricyclic mutanobactins A and B, lipopeptides incorporating a thiazepanone, isolated from Streptococcus mutans, a member of the human oral microbiome. A rapid, solid-phase peptide synthesis (SPPS) based route delivers these natural products from a cascade of cyclization reactions. This versatile process was also employed in a streamlined synthesis of mutanobactin D. Addnl., we provide an independent synthesis of a truncated mutanobactin A analog, utilizing a novel thiazepanone amino acid building block.

Angewandte Chemie, International Edition published new progress about Aldol addition. 22483-09-6 belongs to class alcohols-buliding-blocks, name is 2,2-Dimethoxyethanamine, and the molecular formula is C4H11NO2, Related Products of alcohols-buliding-blocks.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts