Tag: M.W=0-100

Yang, Zeyu; Fu, Hengwei; Ye, Wenjie; Xie, Youyu; Liu, Qinghai; Wang, Hualei; Wei, Dongzhi published the artcile< Efficient asymmetric synthesis of chiral alcohols using high 2-propanol tolerance alcohol dehydrogenase SmADH2 via an environmentally friendly TBCR system>, Name: (R)-Butane-1,3-diol, the main research area is asym synthesis chiral alc propanol oxidation alc dehydrogenase; thermostatic bubble column reactor system alc dehydrogenase ketone reduction.

Alc. dehydrogenases (ADHs) together with the economical substrate-coupled cofactor regeneration system play a pivotal role in the asym. synthesis of chiral alcs.; however, severe challenges concerning the poor tolerance of enzymes to 2-propanol and the adverse effects of the byproduct, acetone, limit its applications, causing this strategy to lapse. Herein, a novel ADH gene smadh2 was identified from Stenotrophomonas maltophilia by traditional genome mining technol. The gene was cloned into Escherichia coli cells and then expressed to yield SmADH2. SmADH2 has a broad substrate spectrum and exhibits excellent tolerance and superb activity to 2-propanol even at 10.5 M (80%, volume/volume) concentration Moreover, a new thermostatic bubble column reactor (TBCR) system is successfully designed to alleviate the inhibition of the byproduct acetone by gas flow and continuously supplement 2-propanol. The organic waste can be simultaneously recovered for the purpose of green synthesis. In the sustainable system, structurally diverse chiral alcs. are synthesized at a high substrate loading (>150 g L-1) without adding external coenzymes. Among these, about 780 g L-1 (6 M) Et acetoacetate is completely converted into Et (R)-3-hydroxybutyrate in only 2.5 h with 99.9% ee and 7488 g L-1 d-1 space-time yield. Mol. dynamics simulation results shed light on the high catalytic activity toward the substrate. Therefore, the high 2-propanol tolerance SmADH2 with the TBCR system proves to be a potent biocatalytic strategy for the synthesis of chiral alcs. on an industrial scale.

Catalysis Science & Technology published new progress about Alcohols, chiral Role: BPN (Biosynthetic Preparation), BIOL (Biological Study), PREP (Preparation). 6290-03-5 belongs to class alcohols-buliding-blocks, and the molecular formula is C4H10O2, Name: (R)-Butane-1,3-diol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Hess, Stephan N.; Mo, Xiaobin; Wirtz, Conny; Fuerstner, Alois published the artcile< Total Synthesis of Limaol>, Product Details of C4H8O, the main research area is limaol total synthesis Stille asym propargylation spirocyclization.

A nonthermodynamic array of four skipped methylene substituents on the hydrophobic tail renders limaol (I), a C40-polyketide of marine origin, unique in structural terms. This conspicuous segment was assembled by a two-directional approach and finally coupled to the polyether domain by an allyl/alkenyl Stille reaction under neutral conditions. The core region itself was prepared via a 3,3′-dibromo-BINOL-catalyzed asym. propargylation, a gold-catalyzed spirocyclization, and introduction of the southern sector via substrate-controlled allylation as the key steps.

Journal of the American Chemical Society published new progress about Diastereoselective synthesis. 627-27-0 belongs to class alcohols-buliding-blocks, and the molecular formula is C4H8O, Product Details of C4H8O.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Sudhakaran, Swetha; Taketoshi, Ayako; Siddiki, S. M. A. Hakim; Murayama, Toru; Nomura, Kotohiro published the artcile< Transesterification of Ethyl-10-undecenoate Using a Cu-Deposited V2O5 Catalyst as a Model Reaction for Efficient Conversion of Plant Oils to Monomers and Fine Chemicals>, Safety of But-3-en-1-ol, the main research area is transesterification ethyl undecenoate copper vanadium oxide catalyst plant oil.

Transesterification of ethyl-10-undecenoate (derived from castor oil) with 1,4-cyclohexanedimethanol over a recyclable Cu-deposited V2O5 catalyst afforded 1,ω-diene, the corresponding cyclohexane-1,4-diylbis(methylene) bis(undec-10-enoate), a promising monomer for the synthesis of biobased polyesters, in an efficient manner. Deposition of Cu plays an important role in proceeding the reaction with high selectivity, and both the activity and the selectivity are preserved for five recycled runs by the addition of the substrates. The present catalyst was effective for transesterification with other alcs., especially primary alcs., demonstrating a possibility of using this catalyst for efficient conversion of plant oil to various fine chems.

ACS Omega published new progress about Castor oil Role: RCT (Reactant), RACT (Reactant or Reagent). 627-27-0 belongs to class alcohols-buliding-blocks, and the molecular formula is C4H8O, Safety of But-3-en-1-ol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Zhai, Pingan; Li, Wenhui; Lin, Jianying; Huang, Shuangping; Gao, Wenchao; Li, Xing published the artcile< N-Alkyl nitrones as substrates for access to N-aryl isoxazolidines via a catalyst-free one-pot three-component reaction with nitroso compounds and olefins>, Computed Properties of 627-27-0, the main research area is nitrosobenzene methylmethanimine oxide ethene catalyst free three component reaction; phenyl isoxazoldine preparation regioselective chemoselective diastereoselective.

N-Alkyl nitrones were used as the starting materials to construct various N-aryl isoxazolidines, via a catalyst-free one-pot three-component reaction with nitroso compounds and olefins. The mechanism investigations indicated that the in-situ formation of N-aryl nitrones from the reaction of N-alkyl nitrones and nitrosoarenes was the key step. The protocol features broad substrate scope, good to excellent chemo-, regio- and diastereo-selectivities, and moderate to excellent yields for most substrates.

Organic Chemistry Frontiers published new progress about Alkenes Role: RCT (Reactant), RACT (Reactant or Reagent). 627-27-0 belongs to class alcohols-buliding-blocks, and the molecular formula is C4H8O, Computed Properties of 627-27-0.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Zhao, Huaibo; McMillan, Alastair J.; Constantin, Timothee; Mykura, Rory C.; Julia, Fabio; Leonori, Daniele published the artcile< Merging Halogen-Atom Transfer (XAT) and Cobalt Catalysis to Override E2-Selectivity in the Elimination of Alkyl Halides: A Mild Route toward contra-Thermodynamic Olefins>, HPLC of Formula: 627-27-0, the main research area is Merging Halogen Atom Transfer Cobalt Catalysis Elimination Alkyl Halides.

We report here a mechanistically distinct tactic to carry E2-type eliminations on alkyl halides. This strategy exploits the interplay of α-aminoalkyl radical-mediated halogen-atom transfer (XAT) with desaturative cobalt catalysis. The methodol. is high-yielding, tolerates many functionalities, and was used to access industrially relevant materials. In contrast to thermal E2 eliminations where unsym. substrates give regioisomeric mixtures, this approach enables, by fine-tuning of the electronic and steric properties of the cobalt catalyst, to obtain high olefin positional selectivity. This unprecedented mechanistic feature has allowed access to contra-thermodn. olefins, elusive by E2 eliminations.

Journal of the American Chemical Society published new progress about Crystal structure. 627-27-0 belongs to class alcohols-buliding-blocks, and the molecular formula is C4H8O, HPLC of Formula: 627-27-0.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Podrojkova, Natalia; Patera, Jan; Popescu, Radian; Skoviera, Jan; Orinakova, Renata; Orinak, Andrej published the artcile< Pyrolysis Degradation of Cellulose over Highly Effective ZnO and ZnO-CuO Nanocatalysts>, Recommanded Product: But-3-en-1-ol, the main research area is zinc copper oxide nanocatalyst cellulose pyrolysis degradation.

Pyrolysis of lignocellulosic biomass with the use of appropriative catalysts can lead to the production of high yields of fuels – bio-oils. Here, zinc oxide – copper oxide (ZnO-CuO) nanocatalysts were synthesized by solvothermal synthesis. High-angle annular dark-field imaging scanning transmission electron microscopy (HAADF-STEM), high-resolution transmission electron microscopy (HRTEM), and energy-dispersive X-ray spectroscopy (EDXS) results suggested that ZnO-CuO nanoparticles (D=23±5 nm) exhibit porous nanostructure. The pyrolytic degradation of cellulose using pyrolysis-gas chromatog.-mass spectrometry (Py-GC/MS) unit has been studied over ZnO and ZnO-CuO nanocatalysts at the temperature range 400-800 °C. The activation energy of ZnO-CuO (67.21 and 70.04 kJ/mol) was lower by 30 kJ/mol from the activation energy of clean ZnO and the calculated rate constants showed that the cellulose pyrolytic reaction is faster using ZnO-CuO catalyst. Nanoporous ZnO-CuO shifted the products maximum towards lower temperatures (< 500 °C), reduced the content of aldehydes at 400-500 °C and enhanced the overall product composition and bio-oil yield. Porous structure of ZnO nanocatalysts had a significant effect on the product selectivity and reaction mechanism of cellulose pyrolysis. ChemistrySelect published new progress about Acids Role: TEM (Technical or Engineered Material Use), USES (Uses). 627-27-0 belongs to class alcohols-buliding-blocks, and the molecular formula is C4H8O, Recommanded Product: But-3-en-1-ol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Yeh, Nai-Hua; Krueger, Ruby; Moeller, Kevin D. published the artcile< Microelectrode Arrays, Dihydroxylation, and the Development of an Orthogonal Safety-Catch Linker>, Recommanded Product: But-3-en-1-ol, the main research area is microelectrode array dihydroxylation orthogonal safety catch linker.

Construction of larger mol. libraries on an addressable microelectrode array requires a method for recovering and characterizing mols. from the surface of any electrode in the array. This method must be orthogonal to the synthetic strategies needed to build the array. The authors report here a method for achieving this goal that employs the site-selective dihydroxylation reaction of a simple olefin.

Organic Letters published new progress about Alkenes Role: PEP (Physical, Engineering or Chemical Process), RCT (Reactant), PROC (Process), RACT (Reactant or Reagent). 627-27-0 belongs to class alcohols-buliding-blocks, and the molecular formula is C4H8O, Recommanded Product: But-3-en-1-ol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Ballesteros-Soberanas, Jordi; Hernandez-Garrido, Juan Carlos; Ceron-Carrasco, Jose Pedro; Leyva-Perez, Antonio published the artcile< Selective semi-hydrogenation of internal alkynes catalyzed by Pd-CaCO3 clusters>, COA of Formula: C4H8O, the main research area is alkene preparation; internal alkyne selective semi hydrogenation palladium catalyst.

The de-novo synthesis of soluble or solid-supported Pd-(CaCO3)n clusters (n = 2-13) and their high catalytic activity for the semi-hydrogenation of internal alkynes compared to terminal alkynes, was presented. Mechanistic studies showed that this reactivity, i.e. internal alkynes more reactive than terminal alkynes, came from the higher electrophilicity of the Pd-(CaCO3)n cluster compared to the nanoparticulated Lindlar catalyst, which unveils the advantages of isolating the min. catalytic unit of a solid catalyst. Translating solid active sites into soluble catalysts turns around the classical approach and constitutes a paradigmatic shift in catalyst design.

Journal of Catalysis published new progress about Alkenes Role: SPN (Synthetic Preparation), PREP (Preparation). 627-27-0 belongs to class alcohols-buliding-blocks, and the molecular formula is C4H8O, COA of Formula: C4H8O.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Dong, Hao; Xu, Cheng-Hua; Yang, Fang-Lu; Du, Lei; Liu, Chen-Long; Chen, Wen-Jing; Wang, Lin published the artcile< 1,4-butanediol selective dehydration to 3-butene-1-ol over calcium-zirconium-tin composite oxide catalysts>, COA of Formula: C4H8O, the main research area is calcium zirconium tin composite oxide catalyst butanediol selective dehydration.

Ca-Zr-Sn composite oxides catalysts for 1,4-butanediol (BDO) selective dehydration to 3-butene-1-ol (BTO) are synthesized by impregnation and co-precipitation in the present work. The results show that Ca-Zr-Sn catalysts prepared from co-precipitation by using NaOH-Na2CO3 mixing alkali solution as precipitant exhibit an excellent catalytic property for BDO dehydration to BTO. For instance, Ca-Zr-Sn oxide with Ca/Zr and Sn/Zr molar ratio of 0.68 and 0.28 calcined at 650 U+00B0C gives a BDO conversion and BTO selectivity of about 97% and 82%, resp., and exhibits no deactivation during 1000 h scale-up exptl. testing. X-ray diffraction results indicate that catalytic active centers for BDO dehydration to BTO are from Ca0.15Zr0.85O crystal phase. NH3- and CO2-temperature programmed desorption prove that the surface of obtained catalysts can provide a large amount of acid and base sites simultaneously. FT-IR spectra of pyridine-adsorbed samples show that acid sites on the surface of Ca-Zr-Sn oxide catalyst mainly exist in a state of Lewis acid, which activates terminal -OH groups of BDO mol. through complexing. The activated -OH interacts with β-H activated on base sites O2- anions relative to Ca species, thereby the CH2=CH- bonds are produced through dehydration to form BTO.

Catalysts published new progress about Calcination. 627-27-0 belongs to class alcohols-buliding-blocks, and the molecular formula is C4H8O, COA of Formula: C4H8O.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Doner, Anna C.; Webb, Annabelle R.; Dewey, Nicholas S.; Hartness, Samuel W.; Christianson, Matthew G.; Koritzke, Alanna L.; Larsson, Alexander; Frandsen, Kelsey M.; Rotavera, Brandon published the artcile< Vacuum-ultraviolet absorption cross-sections of functionalized four-carbon species>, Related Products of 627-27-0, the main research area is four carbon species vacuum UV differential absorption spectroscopy.

Absorption cross-sections were measured in the vacuum UV from 5.17 – 9.92 eV using differential absorption spectroscopy for 33 four-carbon species: n-butane, trans-2-butene, cis-2-butene, butanal, butyric acid, ethyloxirane, trans-2,3-dimethyloxirane, cis-2,3-dimethyloxirane, 2-methyloxetane, 2,2′-bioxirane, vinyl oxirane, 3,4-epoxybutan-2-one, diacetyl, di-Et ether, Et vinyl ether, vinyl acetate, acetic anhydride, 1-butanol, 3-buten-1-ol, 1-hydroxy-butan-2-one, 1-hydroxy-butan-3-one, 2,3-epoxybutan-1-ol, 3,4-epoxybutan-1-ol, 2-oxetanemethanol, butanone, Me vinyl ketone, 4H-1,3-dioxine, allyl formate, 2-oxobutanal, 4-hydroxybutanal, 2-methyloxetan-3-one, cis-but-2-en-1-ol, and trans-2-but-enal. Uncertainties were quantified in all cases by accounting for errors in gas-phase concentration, exptl. repeatability, and signal-to-noise ratio as a function of photon energy. With the exception of 2-oxobutanal, which is reported with an uncertainty of 10%, convolving the sources of error using the root-sum-square method led to an upper limit of 5% uncertainty above the detection limit, which is largely attributable to chem. purity. The primary objective of the present work is to provide absolute cross-sections along with quantified uncertainty limits. The majority of the absorption spectra, which reflect electronic transitions such as σ → σ* and n → σ*, are reported for the first time and provide insight into fundamental chem. physics, such as vibrational band structure and Rydberg transitions. The quant. spectra in the present work facilitates the discovery of chem. intermediates that support improvement in the accuracy of computational models for low-temperature combustion and atm. chem.

Journal of Quantitative Spectroscopy & Radiative Transfer published new progress about Absorption spectra. 627-27-0 belongs to class alcohols-buliding-blocks, and the molecular formula is C4H8O, Related Products of 627-27-0.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts