Tag: M.W=0-100

Rodriguez, Andrea C.; Sad, Maria E.; Cruchade, Hugo; Pinard, Ludovic; Padro, Cristina L. published the artcile< Study of catalyst deactivation during 1,3-butanediol dehydration to produce butadiene>, Electric Literature of 627-27-0, the main research area is tungstophosphoric acid supported catalyst deactivation butanediol dehydration butadiene.

Catalyst deactivation and mechanism of coke formation during the gas phase dehydration of 1,3-butanediol were studied on solid acids of different nature: Al2O3, SiO2/Al2O3, HZSM5 and tungstophosphoric acid (TPA) supported on SiO2. All the catalysts deactivated on stream with a significant coke content ranged between 9% and 14% C. Fresh and spent catalysts as well as carbonaceous deposits were thoroughly characterized using different techniques such as N2 physisorption, FTIR spectroscopy, FTIR of adsorbed pyridine, DSC-TGA, GC-MS and MALDI-TOF MS (matrix-assisted laser desorption/ionization time of flight mass spectrometry). The IR spectra of spent and washed (after direct extraction with CH2Cl2) samples and the superficial soluble coke characterized by MALDI-TOF MS showed the different nature of coke formed in each catalyst with carbonaceous products of higher mol. weights on HZSM5 and TPA/SiO2 than on Al2O3 and SiO2/Al2O3. After catalyst dissolution using hydrofluoric acid and extraction with CH2Cl2 both total soluble and insoluble coke were analyzed. Insoluble coke was only detected on TPA/SiO2 and it was attributed to the strength of its Bronsted acid sites. GC-MS chromatograms of total soluble coke showed the presence of aromatic and polyromantic species, that were very alkylated in the case of HZSM5. Particularly, the well differentiated nature of coke on HZSM5 including alkylnaftalenes and alkylantracenes suggested the coke formation by a shape selectivity mechanism.

Microporous and Mesoporous Materials published new progress about Acidity. 627-27-0 belongs to class alcohols-buliding-blocks, and the molecular formula is C4H8O, Electric Literature of 627-27-0.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Lee, Jeong Hwan; Hong, Suk Bong published the artcile< Dehydration of 1,3-butanediol to butadiene over medium-pore zeolites: Another example of reaction intermediate shape selectivity>, Electric Literature of 627-27-0, the main research area is butanediol butadiene dehydration pore zeolite intermediate shape selectivity.

Here we compare the catalytic properties of the proton form of 11 medium-pore zeolites, with different framework topologies and/or compositions for the dehydration of biomass-derived 1,3-butanediol at 300°C under excess water conditions (H2O/1,3-butanediol = 45). It was found that high-silica H-ferrierite (Si/Al = 130) with intersecting 10- and 8-ring channels exhibits the highest butadiene yield, together with the best durability, among the zeolites tested. Due to its highly inactive nature, however, 3-buten-1-ol, one of the butenol reaction intermediates in 1,3-butanediol dehydration, also remained a major byproduct. IR spectroscopy with adsorbed 3-buten-1-ol shows that intramolecularly hydrogen-bonded 3-buten-1-ol exists predominantly in H-ZSM-5 with two intersecting 10-ring channels, while the one with no intramol. hydrogen bonding is another species found not only in H-ferrierite but also in the one-dimensional 10-ring zeolite H-ZSM-22. By combining both exptl. and theor. results, we conclude that 1,3-butanediol dehydration over medium-pore zeolites may constitute another example of reaction intermediate shape selectivity.

Applied Catalysis, B: Environmental published new progress about Acidity. 627-27-0 belongs to class alcohols-buliding-blocks, and the molecular formula is C4H8O, Electric Literature of 627-27-0.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Mou, Xue-Qing; Ren, Liang-Chen; Zhang, Mei; Wang, Min; Jin, Yu-Fan; Guan, Qing-Xin; Cai, Ang; Zhang, Shi-Min; Ren, Hai; Zhang, Yun; Chen, Yong-Zheng published the artcile< Complementary Copper-Catalyzed and Electrochemical Aminosulfonylation of O-Homoallyl Benzimidates and N-Alkenyl Amidines with Sodium Sulfinates>, HPLC of Formula: 627-27-0, the main research area is alkylsulfonyl oxazine preparation; benzimidate sodium sulfinate copper catalyst aminosulfonylation; alkyl sulfonyl tetrahydropyrimidine preparation; alkenyl amidine sodium sulfinate copper catalyst aminosulfonylation; sulfonyl oxazepine preparation; sodium sulfinate benzimidate trichloroacetimidate copper electrochem aminosulfonylation cyclization regioselective.

A complementary copper-catalyzed and electrochem. aminosulfonylation of O-homoallyl benzimidates/N-alkenyl amidines with sodium sulfinates were developed. The terminal alkene substrate produced Sulfone-containing 1,3-oxazines and tetrahydropyrimidines in the presence of Cu(OAc)2, Ag2CO3 and DPP, and under similar reaction conditions, sulfonylated tetrahydro-1,3-oxazepines were prepared from 1-aryl-substituted O-homoallyl benzimidates in moderate to good yields. For certain electron-rich 1,1- diaryl-substituted alkene substrate, corresponding tetrahydro-1,3-oxazepines was also be obtained in similar or even higher yield via a green electrochem. technique.

Organic Letters published new progress about Alkenes Role: PRP (Properties), RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 627-27-0 belongs to class alcohols-buliding-blocks, and the molecular formula is C4H8O, HPLC of Formula: 627-27-0.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Sudhakaran, Swetha; Siddiki, S. M. A. Hakim; Kitiyanan, Boonyarach; Nomura, Kotohiro published the artcile< CaO Catalyzed Transesterification of Ethyl 10-Undecenoate as a Model Reaction for Efficient Conversion of Plant Oils and Their Application to Depolymerization of Aliphatic Polyesters>, Quality Control of 627-27-0, the main research area is CaO transesterification ethyl undecenoate plant oil depolymerization polyester.

Transesterification of Et 10-undecenoate (derived from castor oil) with cyclohexanemethanol over a CaO catalyst (prebaked at 300 °C) gave undec-10-enoate exclusively (yield 92%, selectivity 95-98%) at 100 °C, and the activity increased at 120 °C with maintaining the high selectivity (97-98%). The transesterification with other alcs., especially primary alcs. (2-ethyl-1-butanol, 1-hexanol, 3-buten-1-ol, and 10-undecen-1-ol), afforded the corresponding esters with high selectivity, indicating the possibility for application of efficient conversion of plant oils to various fine chems. including the monomer for the synthesis of polyesters. Efficient acid-, base-free depolymerization of aliphatic polyesters, poly(ethylene adipate) and poly(butylene adipate), has been demonstrated in this catalysis by transesterification with ethanol and cyclohexanemethanol, affording corresponding adipates and ethylene glycol or butylene glycol exclusively: the reusability of a CaO catalyst has also been demonstrated.

ACS Sustainable Chemistry & Engineering published new progress about Polyesters, aliphatic Role: RCT (Reactant), RACT (Reactant or Reagent). 627-27-0 belongs to class alcohols-buliding-blocks, and the molecular formula is C4H8O, Quality Control of 627-27-0.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Zhang, Youcan; Geng, Hui-Qing; Wu, Xiao-Feng published the artcile< Palladium-Catalyzed Carbonylative Four-Component Synthesis of β-Perfluoroalkyl Amides>, SDS of cas: 627-27-0, the main research area is perfluoroalkyl amide preparation chemoselective; alkene perfluoroalkyl halide amine perfluoroalkylation aminocarbonylation tandem; aminocarbonylation; multicomponent reaction; palladium catalyst; perfluoroalkylation; β-perfluoroalkyl amides.

Transition-metal-catalyzed multicomponent carbonylation is one of the most efficient strategies to construct carbonyl-containing compounds Herein, a palladium-catalyzed four-component perfluoroalkylation/aminocarbonylation of unactivated alkenes with perfluoroalkyl halides, and amines was developed. A wide range of substrates, including anilines, alkylamines, sulfonamides, and hydrazines are all suitable reaction partners for this catalyst system, resulting in various β-perfluoroalkyl amides with good functional-group tolerance and excellent chemoselectivity. Furthermore, not only alkyl olefins, but also aliphatic alkynes, and even alkyl allenes can all be employed. Notably, several medical and bioactive related mols. are compatible here as well.

Chemistry – A European Journal published new progress about Alkenes Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 627-27-0 belongs to class alcohols-buliding-blocks, and the molecular formula is C4H8O, SDS of cas: 627-27-0.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Sheridan, Thomas; Yayla, Hatice G.; Lian, Yajing; Genovino, Julien; Monck, Nat; Burton, Jonathan W. published the artcile< Organophotochemical SNAr Reactions of Mildly Electron-Poor Fluoroarenes>, Safety of (R)-Butane-1,3-diol, the main research area is organophotochem nucleophilic aromatic substitution fluoroarene alc pyrazole blue LEDs.

C-F functionalization of arenes with a range of alc. and pyrazole nucleophiles has been achieved without the need for metal catalysts or highly electron-poor substrates. Treatment of fluoroarenes with alcs. or pyrazoles and DDQ under irradiation by blue LED light provides the corresponding substituted products. The procedure is complementary to classical SNAr chem. which generally requires basic reaction conditions and high temperatures, and provides products under non-basic conditions at ≈ 40°C.

European Journal of Organic Chemistry published new progress about Alcohols Role: RCT (Reactant), RACT (Reactant or Reagent). 6290-03-5 belongs to class alcohols-buliding-blocks, and the molecular formula is C4H10O2, Safety of (R)-Butane-1,3-diol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Liu, Can; Li, Kang; Shang, Rui published the artcile< Arenethiolate as a Dual Function Catalyst for Photocatalytic Defluoroalkylation and Hydrodefluorination of Trifluoromethyls>, Recommanded Product: But-3-en-1-ol, the main research area is difluoroarene preparation; trifluoroarene thiol catalyst photochem defluoroalkylation; difluoroamide preparation; trifluoroacetamide thiol catalyst photochem defluoroalkylation; difluoroacetate preparation; trifluoroacetate thiol catalyst photochem defluoroalkylation.

An arene thiolate with an appropriate substituent was photoactivated under visible light to function as both a strongly reducing electron-donating redox catalyst and a HAT catalyst to enable catalytic C-F activation of trifluoromethyl substrates for selective hydrodefluorination and coupling with various alkenes in the presence of formate salts. These reactions demonstrated the promising utility of arenethiolates as dual function photocatalysts. The synthetic utility of this method was demonstrated by the broad scope of amenable trifluoromethyl substrates, including trifluoromethylated (hetero)arenes, trifluoroacetates, and trifluoroacetamides, which exhibited high levels of chemoselectivity. The reaction efficacy allowed site-selective late-stage functionalization of multitrifluoromethylated bioactive compounds and pharmaceuticals.

ACS Catalysis published new progress about Acetamides Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation) (trifluoro). 627-27-0 belongs to class alcohols-buliding-blocks, and the molecular formula is C4H8O, Recommanded Product: But-3-en-1-ol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Pan, Yani; Blum, Amy Szuchmacher; Simine, Lena; Mauzeroll, Janine published the artcile< Nanometals templated by tobacco mosaic virus coat protein with enhanced catalytic activity>, Recommanded Product: But-3-en-1-ol, the main research area is nanometal tobacco mosaic virus protein green catalyst catalytic activity.

Bio-nano hybrid materials feature eco-friendly synthesis, various self-assembly patterns and numerous possibilities for surface functionalization. With these unique advantages, biol. scaffolds have been regarded as green alternatives to fabricate metallic nanomaterials. Herein, a bulky tobacco mosaic virus coat protein (TMVCP) was employed as a versatile template to synthesize metallic nanoparticles at room temperature These materials exhibited exceptional performance for organic transformations under green conditions. Remarkably, while Au NPs showed rapid kinetics in pollutant 4-nitrophenol reduction, Pd NPs demonstrated superior catalytic activity towards hydrogenation of unsaturated alcs. The enhanced performance is likely related to the protein. To ascertain the protein structure-function effect on the catalytic performance, an in-depth anal. was performed for a TMVCP-Pd NP system via mol. dynamic (MD) simulations. Our results suggest that due to minimal passivation of bulky protein, a large portion of the Pd NP surface remains approachable for the reactants, thus resulting in high reaction rate.

Applied Catalysis, B: Environmental published new progress about Binding energy. 627-27-0 belongs to class alcohols-buliding-blocks, and the molecular formula is C4H8O, Recommanded Product: But-3-en-1-ol.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Singh, Kawaljit; Kaur, Gurminder; Shanika, Petrus Siningu; Dziwornu, Godwin Akpeko; Okombo, John; Chibale, Kelly published the artcile< Structure-activity relationship analyses of fusidic acid derivatives highlight crucial role of the C-21 carboxylic acid moiety to its anti-mycobacterial activity>, SDS of cas: 29335-36-2, the main research area is fusidic acid fusidane triterpenoid synthesis SAR tuberculostatic tuberculosis; Anti-mycobacterial activity; Bioisosteres; Cytotoxicity; Fusidic acid.

Fusidic acid (FA) is a potent congener of the fusidane triterpenoid class of antibiotics. Structure-activity relationship (SAR) studies suggest the chem. structure of FA is optimal for its antibacterial activity. SAR studies from our group within the context of a drug repositioning approach in tuberculosis (TB) suggest that, as with its antibacterial activity, the C-21 carboxylic acid group is indispensable for its anti-mycobacterial activity. Further studies have led to the identification of 16-deacetoxy-16β-ethoxyfusidic acid (58), an analog which exhibited comparable activity to FA with an in vitro MIC99 value of 0.8μM. Preliminary SAR studies around the FA scaffold suggested that the hydrophobic side chain at C-20, like the C-11 OH group, was required for activity. The C-3 OH group, however, can be functionalized to obtain more potent compounds

Bioorganic & Medicinal Chemistry published new progress about Structure-activity relationship. 29335-36-2 belongs to class alcohols-buliding-blocks, and the molecular formula is C3H8N2O, SDS of cas: 29335-36-2.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Yan, Feng-Zhi; Shao, Yuan-Guang; Zhang, Zibin; Shen, Yan-Feng; Huang, Xue-Chun; Zhang, Pei-Ling; Li, Shijun published the artcile< Synthesis of Catenanes from a BMP32C10-Based Cryptand Tuned by the Linkage Length of Paraquat Salts>, Synthetic Route of 627-27-0, the main research area is catenane preparation; BMP32C10 based cryptand paraquat guest olefin metathesis.

A series of catenanes was synthesized through olefin metathesis from a BMP32C10-based cryptand and paraquat guests attached with two terminal alkenes. Distribution of catenane products could be significantly affected by linkage length on paraquat guests. In presence of BMP32C10-based cryptand, paraquat salt with a long linkage facilitates intramol. olefin metathesis to release a [2]catenane as sole catenation product, while use of a paraquat salt with a shorter linkage led to simultaneous generation of [2]-, [3]-, and [4]-catenanes.

Synthesis published new progress about Catenanes Role: SPN (Synthetic Preparation), PREP (Preparation). 627-27-0 belongs to class alcohols-buliding-blocks, and the molecular formula is C4H8O, Synthetic Route of 627-27-0.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts