Tag: 600-700

Liposome-Assisted Enzymatic Modulation of Plasmonic Photoelectrochemistry for Immunoassay was written by Chen, Feng-Zao;Han, De-Man;Chen, Hong-Yuan. And the article was included in Analytical Chemistry (Washington, DC, United States) in 2020.Recommanded Product: (2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl dipalmitate The following contents are mentioned in the article:

Recently emerged liposomal photoelectrochem. (PEC) bioanal. has brought new opportunities for biosensor development. This work presents the new concept of liposome-assisted enzymic modulation of plasmonic photoelectrochem. for PEC bioanal., which was exemplified by an Au nanoclusters (NCs)-sensitized nanoporous TiO₂ nanotubes (Au NC@TiO₂ NT) photoelectrode and an alk. phosphatase (ALP)-loaded liposomal immunoassay of heart-type fatty acid binding protein in a 96-well plate. After sandwich immunorecognition and subsequent lysis treatment, enzymically generated ascorbic acid by the released ALP was directed to reduce Au³⁺ into Au nanoparticles using the Au NCs as seeds, leading to the in situ change of the photoelectrochem. of the electrode and corresponding reduction of the photocurrent. The depressed signal could be correlated with the target concentration with good anal. performance in terms of sensitivity and selectivity. This work features the liposome-assisted enzymic modulation of plasmonic photoelectrochem., which provides a new protocol for general PEC bioanal. development. This study involved multiple reactions and reactants, such as (2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl dipalmitate (cas: 923-61-5Recommanded Product: (2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl dipalmitate).

(2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl dipalmitate (cas: 923-61-5) belongs to alcohols. Alkyl halides are often synthesized from alcohols, in effect substituting a halogen atom for the hydroxyl group. Alcohols may be oxidized to give ketones, aldehydes, and carboxylic acids. These functional groups are useful for further reactions. Oxidation of organic compounds generally increases the number of bonds from carbon to oxygen (or another electronegative element, such as a halogen), and it may decrease the number of bonds to hydrogen.Recommanded Product: (2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl dipalmitate

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Lipid and Protein Transfer between Nanolipoprotein Particles and Supported Lipid Bilayers was written by Dang, Amanda T.;He, Wei;Ivey, Daniela B.;Coleman, Matthew A.;Kuhl, Tonya L.. And the article was included in Langmuir in 2019.Name: (2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl dipalmitate The following contents are mentioned in the article:

A nanolipoprotein particle (NLP) is a lipid bilayer disk stabilized by two amphipathic “scaffold” apolipoproteins. It has been most notably utilized as a tool for solubilizing a variety of membrane proteins while preserving structural and functional properties. Transfer of functional proteins from NLPs into model membrane systems such as supported lipid bilayers (SLBs) would enable new opportunities for example: Two-dimensional protein crystallization and studies on protein-protein interactions. This work used fluorescence microscopy (FM) and at. force microscopy (AFM) to investigate the interaction between NLPs and SLBs. When incubated with SLBs, NLPs were found to spontaneously deliver lipid and protein cargo. The impact of membrane composition on lipid exchange was explored, revealing a pos. correlation between the magnitude of lipid transfer and concentration of defects in the target SLB. Incorporation of lipids capable of binding specifically to polyhistidine tags encoded into the apolipoproteins also boosted transfer of NLP cargo. Optimal conditions for lipid and protein delivery from NLPs to SLBs are proposed based on interaction mechanisms. This study involved multiple reactions and reactants, such as (2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl dipalmitate (cas: 923-61-5Name: (2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl dipalmitate).

(2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl dipalmitate (cas: 923-61-5) belongs to alcohols. Alkyl halides are often synthesized from alcohols, in effect substituting a halogen atom for the hydroxyl group. The most common reactions of alcohols can be classified as oxidation, dehydration, substitution, esterification, and reactions of alkoxides.Name: (2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl dipalmitate

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Pectin-derived neoglycolipids: Tools for differentiation of Shiga toxin subtypes and inhibitors of Shiga toxin-mediated cellular injury was written by Pohlentz, Gottfried;Steil, Daniel;Rubin, Dennis;Mellmann, Alexander;Karch, Helge;Muething, Johannes. And the article was included in Carbohydrate Polymers in 2019.Formula: C37H74NO8P The following contents are mentioned in the article:

Gut pathogenic enterohemorrhagic Escherichia coli (EHEC) release Shiga toxins (Stxs) as major virulence factors, which bind to globotriaosylceramide (Gb3Cer, Galα1-4 Galβ1-4Glcβ1-1Cer) on human target cells. The aim of this study was the production of neoglycolipids (neoGLs) using citrus pectin-derived oligosaccharides and their application as potential inhibitors of Stxs. The preparation of neoGLs starts with the reduction of the carboxylic acid group of the pectic poly(α1-4)GalUA core structure to the corresponding alc., followed by hydrolytic cleavage of resulting poly(α1-4)Gal into (α1-4)Gal_n oligosaccharides and their linkage to phosphatidylethanolamine (PE). Thin-layer chromatog. overlay assays of the produced (α1-4)Gal_n-PE and corresponding Amadori (α1-4)Gal_n=PE neoGLs revealed distinguishable binding patterns for Stx1a, Stx2a, and Stx2e. Furthermore, prepared neoGLs protected Vero cells against the cytotoxic action of Stxs when applied as multivalent glycovesicles. The produced neoGLs are applicable for differentiation of Stx subtypes and represent a promising approach to combat infections of EHEC by blocking their major toxins. This study involved multiple reactions and reactants, such as (2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl dipalmitate (cas: 923-61-5Formula: C37H74NO8P).

(2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl dipalmitate (cas: 923-61-5) belongs to alcohols. Alcohols are among the most common organic compounds. They are used as sweeteners and in making perfumes, are valuable intermediates in the synthesis of other compounds, and are among the most abundantly produced organic chemicals in industry. Converting an alcohol to an alkene requires removal of the hydroxyl group and a hydrogen atom on the neighbouring carbon atom. Dehydrations are most commonly carried out by warming the alcohol in the presence of a strong dehydrating acid, such as concentrated sulfuric acid.Formula: C37H74NO8P

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Ultrasensitive molecularly imprinted electrochemiluminescence sensor based on enzyme-encapsulated liposome-linked signal amplification for trace analysis was written by Liu, Guangyan;Ling, Jun;Xie, Hanzhao;Li, Jianping. And the article was included in Sensors and Actuators, B: Chemical in 2022.Application In Synthesis of (2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl dipalmitate The following contents are mentioned in the article:

A molecularly imprinted polymer (MIP)-electrochemiluminescence (ECL) sensor was prepared and an ultrasensitive strategy was proposed for detecting an ultra-trace amount of ethiprole based on the enzymic signal amplification of glucose oxidase (GOD). The ethiprole mol. on the MIP was marked with GOD-encapsulated liposomes via light-triggered click reaction after elution and readsorption. Many GOD particles were released from the liposomes and catalyzed the reaction to produce a large amount of H2O2 in the presence of glucose, which considerably enhanced the ECL intensity of luminol. Therefore, the sensitivity for ethiprole determination was promoted remarkably. The ECL signal of the sensor was linearly related to the logarithm of ethiprole concentration from 5.00 x 10-16 M to 5.00 x 10-11 M, and the detection limit was 1.00 x 10-16 M, which was the lowest of all the anal. methods used in ethiprole determination Ethiprole in samples was determined directly without the tedious and complicated sample treatment procedures, such as separation and enrichment. The click chem. labeling method using liposomes simplified the operation steps of the MIP-ECL sensor in ethiprole determination This study involved multiple reactions and reactants, such as (2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl dipalmitate (cas: 923-61-5Application In Synthesis of (2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl dipalmitate).

(2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl dipalmitate (cas: 923-61-5) belongs to alcohols. Because alcohols are easily synthesized and easily transformed into other compounds, they serve as important intermediates in organic synthesis. Grignard and organolithium reagents are powerful tools for organic synthesis, and the most common products of their reactions are alcohols.Application In Synthesis of (2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl dipalmitate

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Antibacterial effect of indene on Helicobacter pylori correlates with specific interaction between its compound and dimyristoyl-phosphatidylethanolamine was written by Wanibuchi, Kiyofumi;Takezawa, Motoki;Hosoda, Kouichi;Amgalanbaatar, Avarzed;Tajiri, Kentaro;Koizumi, Yuki;Niitsu, Sakura;Masui, Hisashi;Sakai, Yuki;Shoji, Mitsuru;Takahashi, Takashi;Hirai, Yoshikazu;Shimomura, Hirofumi. And the article was included in Chemistry and Physics of Lipids in 2020.Synthetic Route of C37H74NO8P The following contents are mentioned in the article:

In this study we synthesized a new VDP1 derivative to advance further investigation as for the correlative relationship between VDP1 structure and anti-H. pylori activity or PE vesicle collapse induction activity. The derivative VD3-7 [(1R,7aR)-4-fluoro-7a-methyl-1-((R)-6-methylheptan-2-yl)octahydro-1H-indene] retained a fluorine atom in place of the oxygen atom of VDP1. The fluorination of the carbonyl portion of VDP1 forfeited the effective anti-H. pylori activity. We, therefore, prepared Coomassie brilliant blue (CBB)-containing unilamellar vesicles consisting of various PE mol. species, and examined the vesicle collapse induction activity of either VDP1 or VD3-7 by detecting the CBB eluted from the PE unilamellar vesicles. VDP1 strongly induced CBB elution from the unilamellar vesicles of rectus-PE retaining the same two fatty acid side-chains shorter than carbon numbers 14, indicating that VDP1 specifically disrupted the vesicular conformation of those PE unilamellar vesicles. Meanwhile, VD3-7 had no influence on the structural stability of any PE unilamellar vesicles. This study obtained addnl. evidence that VDP1 acts as a bactericidal agent on H. pylori by targeting the membranal di-14:0 PE. This study involved multiple reactions and reactants, such as (2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl dipalmitate (cas: 923-61-5Synthetic Route of C37H74NO8P).

(2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl dipalmitate (cas: 923-61-5) belongs to alcohols. Because alcohols are easily synthesized and easily transformed into other compounds, they serve as important intermediates in organic synthesis. Grignard and organolithium reagents are powerful tools for organic synthesis, and the most common products of their reactions are alcohols.Synthetic Route of C37H74NO8P

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Enhancing Detection Sensitivity of ZnO-Based Infrared Plasmonic Sensors Using Capped Dielectric Ga₂O₃ Layers for Real-Time Monitoring of Biological Interactions was written by Kuranaga, Yasuhiro;Matsui, Hiroaki;Ikehata, Akifumi;Shimoda, Yuta;Noiri, Makoto;Ho, Ya-Lun;Delaunay, Jean-Jacques;Teramura, Yuji;Tabata, Hitoshi. And the article was included in ACS Applied Bio Materials in 2020.Quality Control of (2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl dipalmitate The following contents are mentioned in the article:

Surface plasmon resonances on Ga-doped ZnO (ZnO/Ga) layer surfaces (ZnO-SPRs) have attracted substantial attention as alternative plasmonic materials in the IR range. We present further enhancement of the detection limits of ZnO-SPRs to monitor biol. interactions by introducing thin dielec. layers into ZnO-SPRs, which remarkably modify the elec. fields and the corresponding decay lengths on the sensing surfaces. The presence of a high-permittivity dielec. layer of Ga₂O₃ provides high wavelength sensitivities of the ZnO-SPRs due to the strongly confined elec. fields. The superior sensing capabilities of the proposed samples were verified by real-time monitoring of the biol. interactions between biotin and streptavidin mols. Introduction of the high-permittivity dielec. layer into ZnO-SPRs effectively enhances the detection sensitivity and therefore allowed for the observation of biol. interactions. This paper provides useful information for the development of optical detection techniques for use in biol. fields based on ZnO from the viewpoints of plasmonic applications. This study involved multiple reactions and reactants, such as (2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl dipalmitate (cas: 923-61-5Quality Control of (2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl dipalmitate).

(2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl dipalmitate (cas: 923-61-5) belongs to alcohols. Similar to water, an alcohol can be pictured as having an sp3 hybridized tetrahedral oxygen atom with nonbonding pairs of electrons occupying two of the four sp3 hybrid orbitals. Converting an alcohol to an alkene requires removal of the hydroxyl group and a hydrogen atom on the neighbouring carbon atom. Dehydrations are most commonly carried out by warming the alcohol in the presence of a strong dehydrating acid, such as concentrated sulfuric acid.Quality Control of (2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl dipalmitate

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

AHNAK C-Terminal Peptide Membrane Binding-Interactions between the Residues 5654-5673 of AHNAK and Phospholipid Monolayers and Bilayers was written by Yan, Xiaolin;Noel, Francis;Marcotte, Isabelle;DeWolf, Christine E.;Warschawski, Dror E.;Boisselier, Elodie. And the article was included in Langmuir in 2020.HPLC of Formula: 923-61-5 The following contents are mentioned in the article:

The dysferlin membrane repair complex contains a small complex, S100A10-annexin A2, which initiates membrane repair by recruiting the protein AHNAK to the membrane, where it interacts via binding sites in the C-terminal region. However, no mol. data are available for the membrane binding of the various proteins involved in this complex. Therefore, the present study investigated the membrane binding of AHNAK to elucidate its role in the cell membrane repair process. An artificially synthesized peptide (pAHNAK), comprising the 20 amino acids in the C-terminal domain of AHNAK, was applied to Langmuir monolayer models, and the binding parameters and insertion angles were measured with surface tensiometry and ellipsometry. The interaction of pAHNAK with lipid bilayers was studied using ³¹P solid-state NMR. PAHNAK preferentially and strongly interacted with phospholipids that comprised neg. charged polar head groups with unsaturated lipids. This finding provides a better understanding of AHNAK membrane behavior and the parameters that influence its function in membrane repair. This study involved multiple reactions and reactants, such as (2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl dipalmitate (cas: 923-61-5HPLC of Formula: 923-61-5).

(2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl dipalmitate (cas: 923-61-5) belongs to alcohols. Alcohols are weak acids. The most acidic simple alcohols (methanol and ethanol) are about as acidic as water, and most other alcohols are somewhat less acidic. Tertiary alcohols cannot be oxidized at all without breaking carbon-carbon bonds, whereas primary alcohols can be oxidized to aldehydes or further oxidized to carboxylic acids.HPLC of Formula: 923-61-5

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Characterization of low temperature-induced plasma membrane lipidome remodeling combined with gene expression analysis reveals mechanisms that regulate membrane lipid desaturation in Carica papaya was written by Chen, Mingjie;Liu, Ruiming;Huang, Xiaohui;Du, Zhenghua;Heng, Shuangpin;Zeng, Wei. And the article was included in Scientia Horticulturae (Amsterdam, Netherlands) in 2020.Synthetic Route of C37H74NO8P The following contents are mentioned in the article:

Carica papaya is a cold-sensitive horticultural crop, the mechanisms underlying its cold sensitivity remains unclear which limit its genetic improvements in cold tolerance. In this study, aqueous dextran-polyethylene glycol two-phase partition systems were applied to purify plasma membrane from papaya leaves grown under 28 °C and 10 °C, the plasma membrane total lipids were analyzed by lipidomic approach. Meanwhile, the transcription levels of putative fatty acid desaturases were quantified by RT-qPCR. We found that cerebrosides are dominate plasma membrane lipid species, followed by phospholipids and free sterols. Cold treatment increased the mono-unsaturated and di-unsaturated phospholipids, and decreased di-saturated phospholipids, the proportion of total phospholipids was not affected. Cold stress enhanced the transcription of CpFAD4, CpFAD6 and CpFAB2-2. Pathway anal. suggested that the cold induction of CpFAB2-2 transcription and CpFAD2 enzyme activities play important roles for plasma membrane lipidome remodeling under cold stress. Our findings uncovered potential targets to improve papaya cold tolerance. This study involved multiple reactions and reactants, such as (2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl dipalmitate (cas: 923-61-5Synthetic Route of C37H74NO8P).

(2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl dipalmitate (cas: 923-61-5) belongs to alcohols. Under appropriate conditions, inorganic acids also react with alcohols to form esters. To form these esters, a wide variety of specialized reagents and conditions can be used. Under carefully controlled conditions, simple alcohols can undergo intermolecular dehydration to give ethers. This reaction is effective only with methanol, ethanol, and other simple primary alcohols.Synthetic Route of C37H74NO8P

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Model System for Antiviral Peptide Transport Characterization was written by Zabrodskaya, Y. A.;Gorshkova, Y. E.;Shyrigina, A.-P. S.;Brodskaya, A. V.;Bobkov, D. E.;Gorshkov, A. N.;Bondarenko, A. B.;Lebedev, D. V.;Egorov, V. V.. And the article was included in Crystallography Reports in 2021.Electric Literature of C37H74NO8P The following contents are mentioned in the article:

Determination of the mechanism of action of potential medicinal substances is an integral stage in development of novel drugs. The interaction of antiviral peptide PB₁₆–₁₄ with lipid membranes in cell and cell-free model systems is demonstrated. Penetration of a fluorescently tagged analog of peptide into cells has been observed for 15 min using continuous-flow cytofluorometry and confocal microscopy. The specific features of interaction of the peptide under study with cell membranes have been studied using small-angle neutron scattering (SANS), at. force microscopy (AFM), and dynamic light scattering. It is shown that model liposomes (PC/PG) increased in size in the presence of peptide (in a 5% ethanol/5% DMSO/PBS buffer), while the ζ potential changed only slightly, which can be interpreted as a consequence of a change in the surface charge and may indicate peptide ability to interact with a lipid bilayer (not excluding its penetration into the membrane). The data obtained can be used both for studying the mechanism of therapeutic peptide transport and for developing drug-delivery agents. This study involved multiple reactions and reactants, such as (2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl dipalmitate (cas: 923-61-5Electric Literature of C37H74NO8P).

(2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl dipalmitate (cas: 923-61-5) belongs to alcohols. Alcohols are among the most common organic compounds. They are used as sweeteners and in making perfumes, are valuable intermediates in the synthesis of other compounds, and are among the most abundantly produced organic chemicals in industry. Tertiary alcohols cannot be oxidized at all without breaking carbon-carbon bonds, whereas primary alcohols can be oxidized to aldehydes or further oxidized to carboxylic acids.Electric Literature of C37H74NO8P

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Tyrosinase-encapsulated liposomes: Toward enzyme-induced in situ sensitization of semiconductor for sensitive photoelectrochemical immunoassay was written by Yu, Si-Yuan;Xue, Tie-Ying;Zhu, Li-Bang;Fan, Gao-Chao;Han, De-Man;Wang, Chengshuang;Zhao, Wei-Wei. And the article was included in Biosensors & Bioelectronics in 2019.COA of Formula: C37H74NO8P The following contents are mentioned in the article:

Liposomal photoelectrochem. (PEC) bioanal. holds enormous potential for future sensitive PEC bioanal. With tyrosinase (Tyr) and TiO₂ as representative enzyme and electrode, resp., this communication reports the elegant use of Tyr-loaded liposomes (TLL) toward in situ sensitization of the electrode and thereby the realization of ultrasensitive PEC immunoassay. Specifically, Tyr-encapsulated and detection antibody-functionalized liposomes were first prepared and used as the signal probe. The subsequent sandwich immunobinding could confine the functional liposomes, which were then lysed with surfactant to release the encapsulated Tyr. The free Tyr could then initiate the transformation of tyrosine to dopa, the latter could bind with the undercoordinated Ti sites, forming the stable dopa-Ti charge transfer complex and thus generating enhanced anodic photocurrent under visible light for signaling. Since different semiconductors and enzymes may be adapted into this format, this work is expected to stimulate more interest in the enzyme-induced activation of semiconductors for advanced liposomal PEC bioanal. This study involved multiple reactions and reactants, such as (2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl dipalmitate (cas: 923-61-5COA of Formula: C37H74NO8P).

(2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl dipalmitate (cas: 923-61-5) belongs to alcohols. Similar to water, an alcohol can be pictured as having an sp3 hybridized tetrahedral oxygen atom with nonbonding pairs of electrons occupying two of the four sp3 hybrid orbitals. Alcohols may be oxidized to give ketones, aldehydes, and carboxylic acids. These functional groups are useful for further reactions. Oxidation of organic compounds generally increases the number of bonds from carbon to oxygen (or another electronegative element, such as a halogen), and it may decrease the number of bonds to hydrogen.COA of Formula: C37H74NO8P

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts