Tag: 600-700

Assessing collision cross section calibration strategies for traveling wave-based ion mobility separations in structures for lossless ion manipulations was written by Li, Ailin;Conant, Christopher R.;Zheng, Xueyun;Bloodsworth, Kent J.;Orton, Daniel J.;Garimella, Sandilya V. B.;Attah, Isaac K.;Nagy, Gabe;Smith, Richard D.;Ibrahim, Yehia M.. And the article was included in Analytical Chemistry (Washington, DC, United States) in 2020.Product Details of 923-61-5 The following contents are mentioned in the article:

The collision cross section (CCS) is an important property that aids in the structural characterization of mols. Here, we investigated the CCS calibration accuracy with traveling wave ion mobility spectrometry (TWIMS) separations in structures for lossless ion manipulations (SLIM) using three sets of calibrants. A series of singly neg. charged phospholipids and bile acids were calibrated in nitrogen buffer gas using two different TW waveform profiles (square and sine) and amplitudes (20, 25, and 30 V_0-p). The calibration errors for the three calibrant sets (Agilent tuning mixture, polyalanine, and one assembled inhouse) showed negligible differences using a sine-shaped TW waveform. Calibration errors were all within 1-2% of the drift tube ion mobility spectrometry (DTIMS) measurements, with lower errors for sine waveforms, presumably due to the lower average and maximum fields experienced by ions. Finally, ultrahigh-resolution multipass (long path length) SLIM TWIMS separations demonstrated improved CCS calibration for phospholipid and bile acid isomers. This study involved multiple reactions and reactants, such as (2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl dipalmitate (cas: 923-61-5Product Details of 923-61-5).

(2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl dipalmitate (cas: 923-61-5) belongs to alcohols. Because alcohols are easily synthesized and easily transformed into other compounds, they serve as important intermediates in organic synthesis. The most common reactions of alcohols can be classified as oxidation, dehydration, substitution, esterification, and reactions of alkoxides.Product Details of 923-61-5

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Enhancing Detection Sensitivity of ZnO-Based Infrared Plasmonic Sensors Using Capped Dielectric Ga₂O₃ Layers for Real-Time Monitoring of Biological Interactions was written by Kuranaga, Yasuhiro;Matsui, Hiroaki;Ikehata, Akifumi;Shimoda, Yuta;Noiri, Makoto;Ho, Ya-Lun;Delaunay, Jean-Jacques;Teramura, Yuji;Tabata, Hitoshi. And the article was included in ACS Applied Bio Materials in 2020.Quality Control of (2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl dipalmitate The following contents are mentioned in the article:

Surface plasmon resonances on Ga-doped ZnO (ZnO/Ga) layer surfaces (ZnO-SPRs) have attracted substantial attention as alternative plasmonic materials in the IR range. We present further enhancement of the detection limits of ZnO-SPRs to monitor biol. interactions by introducing thin dielec. layers into ZnO-SPRs, which remarkably modify the elec. fields and the corresponding decay lengths on the sensing surfaces. The presence of a high-permittivity dielec. layer of Ga₂O₃ provides high wavelength sensitivities of the ZnO-SPRs due to the strongly confined elec. fields. The superior sensing capabilities of the proposed samples were verified by real-time monitoring of the biol. interactions between biotin and streptavidin mols. Introduction of the high-permittivity dielec. layer into ZnO-SPRs effectively enhances the detection sensitivity and therefore allowed for the observation of biol. interactions. This paper provides useful information for the development of optical detection techniques for use in biol. fields based on ZnO from the viewpoints of plasmonic applications. This study involved multiple reactions and reactants, such as (2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl dipalmitate (cas: 923-61-5Quality Control of (2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl dipalmitate).

(2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl dipalmitate (cas: 923-61-5) belongs to alcohols. Similar to water, an alcohol can be pictured as having an sp3 hybridized tetrahedral oxygen atom with nonbonding pairs of electrons occupying two of the four sp3 hybrid orbitals. Converting an alcohol to an alkene requires removal of the hydroxyl group and a hydrogen atom on the neighbouring carbon atom. Dehydrations are most commonly carried out by warming the alcohol in the presence of a strong dehydrating acid, such as concentrated sulfuric acid.Quality Control of (2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl dipalmitate

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

AHNAK C-Terminal Peptide Membrane Binding-Interactions between the Residues 5654-5673 of AHNAK and Phospholipid Monolayers and Bilayers was written by Yan, Xiaolin;Noel, Francis;Marcotte, Isabelle;DeWolf, Christine E.;Warschawski, Dror E.;Boisselier, Elodie. And the article was included in Langmuir in 2020.HPLC of Formula: 923-61-5 The following contents are mentioned in the article:

The dysferlin membrane repair complex contains a small complex, S100A10-annexin A2, which initiates membrane repair by recruiting the protein AHNAK to the membrane, where it interacts via binding sites in the C-terminal region. However, no mol. data are available for the membrane binding of the various proteins involved in this complex. Therefore, the present study investigated the membrane binding of AHNAK to elucidate its role in the cell membrane repair process. An artificially synthesized peptide (pAHNAK), comprising the 20 amino acids in the C-terminal domain of AHNAK, was applied to Langmuir monolayer models, and the binding parameters and insertion angles were measured with surface tensiometry and ellipsometry. The interaction of pAHNAK with lipid bilayers was studied using ³¹P solid-state NMR. PAHNAK preferentially and strongly interacted with phospholipids that comprised neg. charged polar head groups with unsaturated lipids. This finding provides a better understanding of AHNAK membrane behavior and the parameters that influence its function in membrane repair. This study involved multiple reactions and reactants, such as (2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl dipalmitate (cas: 923-61-5HPLC of Formula: 923-61-5).

(2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl dipalmitate (cas: 923-61-5) belongs to alcohols. Alcohols are weak acids. The most acidic simple alcohols (methanol and ethanol) are about as acidic as water, and most other alcohols are somewhat less acidic. Tertiary alcohols cannot be oxidized at all without breaking carbon-carbon bonds, whereas primary alcohols can be oxidized to aldehydes or further oxidized to carboxylic acids.HPLC of Formula: 923-61-5

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Characterization of low temperature-induced plasma membrane lipidome remodeling combined with gene expression analysis reveals mechanisms that regulate membrane lipid desaturation in Carica papaya was written by Chen, Mingjie;Liu, Ruiming;Huang, Xiaohui;Du, Zhenghua;Heng, Shuangpin;Zeng, Wei. And the article was included in Scientia Horticulturae (Amsterdam, Netherlands) in 2020.Synthetic Route of C37H74NO8P The following contents are mentioned in the article:

Carica papaya is a cold-sensitive horticultural crop, the mechanisms underlying its cold sensitivity remains unclear which limit its genetic improvements in cold tolerance. In this study, aqueous dextran-polyethylene glycol two-phase partition systems were applied to purify plasma membrane from papaya leaves grown under 28 °C and 10 °C, the plasma membrane total lipids were analyzed by lipidomic approach. Meanwhile, the transcription levels of putative fatty acid desaturases were quantified by RT-qPCR. We found that cerebrosides are dominate plasma membrane lipid species, followed by phospholipids and free sterols. Cold treatment increased the mono-unsaturated and di-unsaturated phospholipids, and decreased di-saturated phospholipids, the proportion of total phospholipids was not affected. Cold stress enhanced the transcription of CpFAD4, CpFAD6 and CpFAB2-2. Pathway anal. suggested that the cold induction of CpFAB2-2 transcription and CpFAD2 enzyme activities play important roles for plasma membrane lipidome remodeling under cold stress. Our findings uncovered potential targets to improve papaya cold tolerance. This study involved multiple reactions and reactants, such as (2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl dipalmitate (cas: 923-61-5Synthetic Route of C37H74NO8P).

(2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl dipalmitate (cas: 923-61-5) belongs to alcohols. Under appropriate conditions, inorganic acids also react with alcohols to form esters. To form these esters, a wide variety of specialized reagents and conditions can be used. Under carefully controlled conditions, simple alcohols can undergo intermolecular dehydration to give ethers. This reaction is effective only with methanol, ethanol, and other simple primary alcohols.Synthetic Route of C37H74NO8P

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Model System for Antiviral Peptide Transport Characterization was written by Zabrodskaya, Y. A.;Gorshkova, Y. E.;Shyrigina, A.-P. S.;Brodskaya, A. V.;Bobkov, D. E.;Gorshkov, A. N.;Bondarenko, A. B.;Lebedev, D. V.;Egorov, V. V.. And the article was included in Crystallography Reports in 2021.Electric Literature of C37H74NO8P The following contents are mentioned in the article:

Determination of the mechanism of action of potential medicinal substances is an integral stage in development of novel drugs. The interaction of antiviral peptide PB₁₆–₁₄ with lipid membranes in cell and cell-free model systems is demonstrated. Penetration of a fluorescently tagged analog of peptide into cells has been observed for 15 min using continuous-flow cytofluorometry and confocal microscopy. The specific features of interaction of the peptide under study with cell membranes have been studied using small-angle neutron scattering (SANS), at. force microscopy (AFM), and dynamic light scattering. It is shown that model liposomes (PC/PG) increased in size in the presence of peptide (in a 5% ethanol/5% DMSO/PBS buffer), while the ζ potential changed only slightly, which can be interpreted as a consequence of a change in the surface charge and may indicate peptide ability to interact with a lipid bilayer (not excluding its penetration into the membrane). The data obtained can be used both for studying the mechanism of therapeutic peptide transport and for developing drug-delivery agents. This study involved multiple reactions and reactants, such as (2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl dipalmitate (cas: 923-61-5Electric Literature of C37H74NO8P).

(2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl dipalmitate (cas: 923-61-5) belongs to alcohols. Alcohols are among the most common organic compounds. They are used as sweeteners and in making perfumes, are valuable intermediates in the synthesis of other compounds, and are among the most abundantly produced organic chemicals in industry. Tertiary alcohols cannot be oxidized at all without breaking carbon-carbon bonds, whereas primary alcohols can be oxidized to aldehydes or further oxidized to carboxylic acids.Electric Literature of C37H74NO8P

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Tyrosinase-encapsulated liposomes: Toward enzyme-induced in situ sensitization of semiconductor for sensitive photoelectrochemical immunoassay was written by Yu, Si-Yuan;Xue, Tie-Ying;Zhu, Li-Bang;Fan, Gao-Chao;Han, De-Man;Wang, Chengshuang;Zhao, Wei-Wei. And the article was included in Biosensors & Bioelectronics in 2019.COA of Formula: C37H74NO8P The following contents are mentioned in the article:

Liposomal photoelectrochem. (PEC) bioanal. holds enormous potential for future sensitive PEC bioanal. With tyrosinase (Tyr) and TiO₂ as representative enzyme and electrode, resp., this communication reports the elegant use of Tyr-loaded liposomes (TLL) toward in situ sensitization of the electrode and thereby the realization of ultrasensitive PEC immunoassay. Specifically, Tyr-encapsulated and detection antibody-functionalized liposomes were first prepared and used as the signal probe. The subsequent sandwich immunobinding could confine the functional liposomes, which were then lysed with surfactant to release the encapsulated Tyr. The free Tyr could then initiate the transformation of tyrosine to dopa, the latter could bind with the undercoordinated Ti sites, forming the stable dopa-Ti charge transfer complex and thus generating enhanced anodic photocurrent under visible light for signaling. Since different semiconductors and enzymes may be adapted into this format, this work is expected to stimulate more interest in the enzyme-induced activation of semiconductors for advanced liposomal PEC bioanal. This study involved multiple reactions and reactants, such as (2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl dipalmitate (cas: 923-61-5COA of Formula: C37H74NO8P).

(2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl dipalmitate (cas: 923-61-5) belongs to alcohols. Similar to water, an alcohol can be pictured as having an sp3 hybridized tetrahedral oxygen atom with nonbonding pairs of electrons occupying two of the four sp3 hybrid orbitals. Alcohols may be oxidized to give ketones, aldehydes, and carboxylic acids. These functional groups are useful for further reactions. Oxidation of organic compounds generally increases the number of bonds from carbon to oxygen (or another electronegative element, such as a halogen), and it may decrease the number of bonds to hydrogen.COA of Formula: C37H74NO8P

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Antitrypanosomal activity of epi-polygodial from Drimys brasiliensis and its effects in cellular membrane models at the air-water interface was written by Goncalves, Giulia Elisa Guimaraes;Morais, Thiago Rahal;Gomes, Kaio de Souza;Costa-Silva, Thais Alves;Tempone, Andre Gustavo;Lago, Joao Henrique Ghilardi;Caseli, Luciano. And the article was included in Bioorganic Chemistry in 2019.COA of Formula: C37H74NO8P The following contents are mentioned in the article:

Epi-polygodial, a drimane sesquiterpene was isolated from Drimys brasiliensis (Winteraceae). This compound demonstrated high parasite selectivity towards Trypanosoma cruzi trypomastigotes (IC₅₀ = 5.01 μM) with a selectivity index higher than 40. These results were correlated with the effects observed when this compound was incorporated in cellular membrane models of protozoans, represented by Langmuir monolayers of dipalmitoylphosphoethanolamine (DPPE). Surface pressure-area isotherms showed that epi-polygodial expands DPPE monolayers at higher areas and condenses them at lower areas, which was attributed to the preferential interaction with the polar heads of the lipid. This mechanism of action could be corroborated with Polarization-Modulation Reflection-Absorption Spectroscopy and Brewster Angle Microscopy. These results pointed to the fact that the interaction of epi-polygodial with DPPE monolayers at the air-water interface affects the phys. chem. properties of the mixed film, which may be important to comprehend the interaction of this drug with cellular membranes at the mol. level. This study involved multiple reactions and reactants, such as (2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl dipalmitate (cas: 923-61-5COA of Formula: C37H74NO8P).

(2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl dipalmitate (cas: 923-61-5) belongs to alcohols. A strong base can deprotonate an alcohol to yield an alkoxide ion (R―O−). For example, sodamide (NaNH2), a very strong base, abstracts the hydrogen atom of an alcohol. Converting an alcohol to an alkene requires removal of the hydroxyl group and a hydrogen atom on the neighbouring carbon atom. Dehydrations are most commonly carried out by warming the alcohol in the presence of a strong dehydrating acid, such as concentrated sulfuric acid.COA of Formula: C37H74NO8P

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Theoretical study of rhodium- and cobalt-catalyzed decarboxylative transformations of isoxazolones: origin of product selectivity was written by Rong, Wei;Zhang, Tian;Li, Ting;Li, Juan. And the article was included in Organic Chemistry Frontiers in 2021.Related Products of 923-61-5 The following contents are mentioned in the article:

Divergent catalytic reactions provide access to diverse nitrogen-containing heterocycles through controlled catalysts. This study presents a computational study of rhodium- and cobalt-catalyzed decarboxylative transformations of isoxazolones. The calculations clarified the mechanistic details of the reaction and the origins of the catalyst controlled product selectivity. We identified a mechanism in which alkene insertion precedes CO₂ elimination in rhodium- and cobalt-catalyzed decarboxylative transformations of isoxazolones. The kinetic feasibility of this mechanism is attributed to the avoidance of formation of a highly unstable four-membered rhodacycle intermediate. The reason for the formation of different products with the two metals lies in the different geometries of the metal centers in the key transition states. The energy barrier of C-N-bond-forming reductive elimination via the triplet state for the cobalt system is small because the distorted trigonal-bipyramidal coordination geometry of the transition state maximizes the overlap between the π* orbital of the N atom and the σ* orbital of the C atom. This study involved multiple reactions and reactants, such as (2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl dipalmitate (cas: 923-61-5Related Products of 923-61-5).

(2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl dipalmitate (cas: 923-61-5) belongs to alcohols. Alcohols are weak acids. The most acidic simple alcohols (methanol and ethanol) are about as acidic as water, and most other alcohols are somewhat less acidic. The most common reactions of alcohols can be classified as oxidation, dehydration, substitution, esterification, and reactions of alkoxides.Related Products of 923-61-5

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

A Trifunctional Linker for Palmitoylation and Peptide and Protein Localization in Biological Membranes was written by Syga, Lukasz;de Vries, Reinder H.;van Oosterhout, Hugo;Bartelds, Rianne;Boersma, Arnold J.;Roelfes, Gerard;Poolman, Bert. And the article was included in ChemBioChem in 2020.Safety of (2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl dipalmitate The following contents are mentioned in the article:

Attachment of lipophilic groups is an important post-translational modification of proteins, which involves the coupling of one or more anchors such as fatty acids, isoprenoids, phospholipids, or glycosylphosphatidyl inositols. To study its impact on the membrane partitioning of hydrophobic peptides or proteins, we designed a tyrosine-based trifunctional linker. The linker allows the facile incorporation of two different functionalities at a cysteine residue in a single step. We determined the effect of the lipid modification on the membrane partitioning of the synthetic a-helical model peptide WALP with or without here and in all cases below; palmitoyl groups in giant unilamellar vesicles that contain a liquid-ordered (L_o) and liquid-disordered (L_d) phase. Introduction of two palmitoyl groups did not alter the localization of the membrane peptides, nor did the membrane thickness or lipid composition In all cases, the peptide was retained in the L_d phase. These data demonstrate that the L_o domain in model membranes is highly unfavorable for a single membrane-spanning peptide. This study involved multiple reactions and reactants, such as (2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl dipalmitate (cas: 923-61-5Safety of (2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl dipalmitate).

(2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl dipalmitate (cas: 923-61-5) belongs to alcohols. Alcohols are among the most common organic compounds. They are used as sweeteners and in making perfumes, are valuable intermediates in the synthesis of other compounds, and are among the most abundantly produced organic chemicals in industry. The most common reactions of alcohols can be classified as oxidation, dehydration, substitution, esterification, and reactions of alkoxides.Safety of (2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl dipalmitate

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Contribution of headgroup and chain length of glycerophospholipids to thermal stability and permeability of liposomes loaded with calcein was written by Prislan, Iztok;Lokar, Marusa;Zirdum, Martina;Valant, Janez;Poklar Ulrih, Natasa. And the article was included in Chemistry and Physics of Lipids in 2019.Name: (2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl dipalmitate The following contents are mentioned in the article:

Biol. membranes are complex systems that are composed of lipids, proteins and carbohydrates. They are difficult to study, so it is established practice to use lipid vesicles that consist of closed ‘shells’ of phospholipid bilayers as model systems to study various functional and structural aspects of lipid organization. To define the effects of the structural properties of lipid vesicles on their phase behavior, we investigated their headgroup and chain length, and the chem. bonds by which their acyl chains are attached to the glycerol moiety of glycerophospholipid species, in terms of phase transition temperature, enthalpy change and calcein permeability. We used differential scanning calorimetry to measure the temperature and enthalpy changes of phase transition, and fluorescence to follow calcein release through the bilayer structure. Our data show that longer acyl chains increase the stability of the lipid bilayers, whereas higher salt concentrations decrease the thermal stability and widen the phase transitions of these lipid bilayers. We discuss the possible reasons for the observed phase transition behavior. This study involved multiple reactions and reactants, such as (2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl dipalmitate (cas: 923-61-5Name: (2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl dipalmitate).

(2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl dipalmitate (cas: 923-61-5) belongs to alcohols. A strong base can deprotonate an alcohol to yield an alkoxide ion (R―O−). For example, sodamide (NaNH2), a very strong base, abstracts the hydrogen atom of an alcohol. Tertiary alcohols cannot be oxidized at all without breaking carbon-carbon bonds, whereas primary alcohols can be oxidized to aldehydes or further oxidized to carboxylic acids.Name: (2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl dipalmitate

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts