Tag: 500-600

TLC-Based Fingerprinting Analysis of the Geographical Variation of Melastoma malabathricum in Inland and Archipelago Regions: A Rapid and Easy-to-Use Tool for Field Metabolomics Studies was written by Mayasari, Dian;Murti, Yosi Bayu;Pratiwi, Sylvia Utami Tunjung;Sudarsono, Sudarsono;Hanna, George;Hamann, Mark T.. And the article was included in Journal of Natural Products in 2022.Reference of 29106-49-8 The following contents are mentioned in the article:

Melastoma malabathricum is an Indo-Pacific herb that has been used traditionally to treat numerous ailments such as wounds, dysentery, diarrhea, toothache, and diabetes. The objective of this study was to evaluate the variability of the metabolic profiles of M. malabathricum across its geog. distribution. By employing thin layer chromatog. (TLC), specimens collected from six terrestrial and archipelago regions of Indonesia were analyzed by densitometry for metabolomic fingerprinting anal. combined with chemometric tools: principal component anal. (PCA) and hierarchical cluster anal. (HCA). Two PCAs were identified as PC1 and PC2 with 41.90% and 20.36%, resp. Our results indicate the importance of considering geog. distribution during field-collection efforts since they demonstrate regional metabolic variation in secondary metabolites of M. malabathricum, as illustrated by TLC and their biol. activities. This study involved multiple reactions and reactants, such as (2R,2’R,3R,3’R,4R)-2,2′-Bis(3,4-dihydroxyphenyl)-[4,8′-bichromane]-3,3′,5,5′,7,7′-hexaol (cas: 29106-49-8Reference of 29106-49-8).

(2R,2’R,3R,3’R,4R)-2,2′-Bis(3,4-dihydroxyphenyl)-[4,8′-bichromane]-3,3′,5,5′,7,7′-hexaol (cas: 29106-49-8) belongs to alcohols. The oxygen atom of the strongly polarized O―H bond of an alcohol pulls electron density away from the hydrogen atom. This polarized hydrogen, which bears a partial positive charge, can form a hydrogen bond with a pair of nonbonding electrons on another oxygen atom. Under carefully controlled conditions, simple alcohols can undergo intermolecular dehydration to give ethers. This reaction is effective only with methanol, ethanol, and other simple primary alcohols.Reference of 29106-49-8

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Preventive Effect of Apple Polyphenol Extract on High-Fat Diet-Induced Hepatic Steatosis in Mice through Alleviating Endoplasmic Reticulum Stress was written by Yan, Bei;Chen, Lei;Wang, Yanhui;Zhang, Jiacheng;Zhao, Hui;Hua, Qinglian;Pei, Shengjie;Yue, Zihang;Liang, Hui;Zhang, Huaqi. And the article was included in Journal of Agricultural and Food Chemistry in 2022.Application of 29106-49-8 The following contents are mentioned in the article:

In this work, the protective effect of apple polyphenol extract (APE) on hepatic steatosis was investigated. Thirty-two C57BL/6J mice were assigned randomly to control group, hepatic steatosis group, lovastatin group, and APE group. After 8 wk of intervention, APE supplementation markedly decreased the body weight gain, liver weight, liver index, epididymal adipose weight, epididymal adipose index, serum, and hepatic lipid levels. Hematoxylin and eosin staining revealed that APE supplementation alleviated histopathol. changes of hepatic steatosis. Western blot revealed that APE downregulated the protein levels of GRP78, IRE1α, p-IRE1α, XBP1, PERK, p-PERK, p-eIF2α, ATF6, PPAR-γ, SREBP-1c, FAS, and ACC1. In conclusion, this study found that APE inhibited IRE1α-XBP1, PERK-eIF2α, and ATF6 signaling pathways to alleviate endoplasmic reticulum stress, thereby improving HFD-induced hepatic steatosis. This study involved multiple reactions and reactants, such as (2R,2’R,3R,3’R,4R)-2,2′-Bis(3,4-dihydroxyphenyl)-[4,8′-bichromane]-3,3′,5,5′,7,7′-hexaol (cas: 29106-49-8Application of 29106-49-8).

(2R,2’R,3R,3’R,4R)-2,2′-Bis(3,4-dihydroxyphenyl)-[4,8′-bichromane]-3,3′,5,5′,7,7′-hexaol (cas: 29106-49-8) belongs to alcohols. The oxygen atom of the strongly polarized O―H bond of an alcohol pulls electron density away from the hydrogen atom. This polarized hydrogen, which bears a partial positive charge, can form a hydrogen bond with a pair of nonbonding electrons on another oxygen atom. Secondary alcohols are easily oxidized without breaking carbon-carbon bonds only as far as the ketone stage. No further oxidation is seen except under very stringent conditions.Application of 29106-49-8

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Changes in Proanthocyanidin Content during the Processing of Umeshu, a Spirit-Based Liqueur of Japanese Apricot (Prunus mume Sieb. et Zucc.) Fruit was written by Horinishi, Asako;Toyama, Yoshimasa;Watanabe, Minoru;Ayano, Shigeru;Ozaki, Yoshihiko. And the article was included in ACS Food Science & Technology in 2022.Related Products of 29106-49-8 The following contents are mentioned in the article:

Japanese apricot (Prunus mume Sieb. et.Zucc.), also known as Ume, is used as a food item and a folk remedy in most east Asian countries, including Japan. Umeshu is a liqueur made from Ume and is one of the most popular products obtained from this fruit. The polyphenols (PPs) and proanthocyanidins (PAs) present in Umeshu and the residual fruit obtained post immersion were analyzed. We are the first to report the characteristics of the phenolic compounds obtained during the processing of Umeshu. The concentration of PA in Umeshu was approx. 16μg/mL, and this concentration was significantly lower than the concentrations of PA present in other liqueurs. It is believed that most of the PAs contained in Umeshu leach out from the endocarp. The total amounts of extractable PAs decreased, and the total amounts of nonextractable PAs increased in Umeshu and the residual fruit during the processing stage. This study involved multiple reactions and reactants, such as (2R,2’R,3R,3’R,4R)-2,2′-Bis(3,4-dihydroxyphenyl)-[4,8′-bichromane]-3,3′,5,5′,7,7′-hexaol (cas: 29106-49-8Related Products of 29106-49-8).

(2R,2’R,3R,3’R,4R)-2,2′-Bis(3,4-dihydroxyphenyl)-[4,8′-bichromane]-3,3′,5,5′,7,7′-hexaol (cas: 29106-49-8) belongs to alcohols. A strong base can deprotonate an alcohol to yield an alkoxide ion (R―O−). For example, sodamide (NaNH2), a very strong base, abstracts the hydrogen atom of an alcohol. Tertiary alcohols cannot be oxidized at all without breaking carbon-carbon bonds, whereas primary alcohols can be oxidized to aldehydes or further oxidized to carboxylic acids.Related Products of 29106-49-8

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Evaluating the changes in phytochemical composition, hypoglycemic effect, and influence on mice intestinal microbiota of fermented apple juice was written by Wang, Xiaowei;Wang, Yaqin;Han, Mengzhen;Liang, Jingjing;Zhang, Meina;Bai, Xue;Yue, Tianli;Gao, Zhenpeng. And the article was included in Food Research International in 2022.Computed Properties of C30H26O12 The following contents are mentioned in the article:

Apples are rich in phenolic antioxidants, which have various beneficial effects on human health. The purposes of our study were to evaluate the effects of Lactobacillus fermentum 21828 fermentation on the phytochem. composition and bioactivity of Aksu (Fuji) apple juice (AJ), and to evaluate the hypoglycemic effect of fermented AJ (FAJ) and its effect on intestinal flora. Fermentation altered the phytochem. and enhanced the biol. activity (hypoglycemic and antioxidant activities) of AJ. FAJ improved fasting blood glucose and insulin levels in diabetic mice, regulated blood lipid metabolism, reduced oxidative damage, restored damaged islet cells, and reshaped the intestinal flora of diabetic mice by increasing the relative abundance of Actinobacteria, Bifidobacteria, and Faecalibaculum. The results indicate that FAJ is a fermented product that is rich in bioactive components and has potential hypoglycemic and antioxidant activities. This study involved multiple reactions and reactants, such as (2R,2’R,3R,3’R,4R)-2,2′-Bis(3,4-dihydroxyphenyl)-[4,8′-bichromane]-3,3′,5,5′,7,7′-hexaol (cas: 29106-49-8Computed Properties of C30H26O12).

(2R,2’R,3R,3’R,4R)-2,2′-Bis(3,4-dihydroxyphenyl)-[4,8′-bichromane]-3,3′,5,5′,7,7′-hexaol (cas: 29106-49-8) belongs to alcohols. Under appropriate conditions, inorganic acids also react with alcohols to form esters. To form these esters, a wide variety of specialized reagents and conditions can be used. A multistep synthesis may use Grignard-like reactions to form an alcohol with the desired carbon structure, followed by reactions to convert the hydroxyl group of the alcohol to the desired functionality.Computed Properties of C30H26O12

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Enzymatic modification of oat globulin enables covalent interaction with procyanidin B2 was written by Korpela, Bei;Pitkanen, Leena;Heinonen, Marina. And the article was included in Food Chemistry in 2022.COA of Formula: C30H26O12 The following contents are mentioned in the article:

The effect of enzyme treatment on protein-tannin interactions was investigated using up-to-date anal. approaches for improving their phys. properties. The formation of ligands between procyanidin B2 and native oat globulin (OG) was observed to be affected by the ratio of procyanidin B2 to OG and the availability of tryptophan. For the transglutaminase-treated OG, the results obtained from CD (CD) and size exclusion chromatog. (SEC) revealed that procyanidin B2 acted as an acyl acceptor in the process of OG deamidation. Procyanidin B2 also inhibited the non-covalent protein-protein interactions occurring between the aromatic side-chains or sedimentation of tryptophan aggregates. For trypsin-treated OG, procyanidin B2 interacted with phenylalanine and the tryptophan side-chain of OG. The inhibition of procyanidin B2 towards protein-protein aggregation was proved by the observation of CD, SEC and asym. flow field-flow fractionation. This study involved multiple reactions and reactants, such as (2R,2’R,3R,3’R,4R)-2,2′-Bis(3,4-dihydroxyphenyl)-[4,8′-bichromane]-3,3′,5,5′,7,7′-hexaol (cas: 29106-49-8COA of Formula: C30H26O12).

(2R,2’R,3R,3’R,4R)-2,2′-Bis(3,4-dihydroxyphenyl)-[4,8′-bichromane]-3,3′,5,5′,7,7′-hexaol (cas: 29106-49-8) belongs to alcohols. Because alcohols are easily synthesized and easily transformed into other compounds, they serve as important intermediates in organic synthesis. Tertiary alcohols cannot be oxidized at all without breaking carbon-carbon bonds, whereas primary alcohols can be oxidized to aldehydes or further oxidized to carboxylic acids.COA of Formula: C30H26O12

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Construction of Optically Active Quaternary Propargyl Amines by Highly Enantioselective Zinc/BINOL-Catalyzed Alkynylation of Ketoimines was written by Huang, Gaochao;Yin, Zengsheng;Zhang, Xingang. And the article was included in Chemistry – A European Journal in 2013.Application In Synthesis of (R)-[1,3′:1′,1”:3”,1”’-Quaternaphthalene]-2′,2”-diol The following contents are mentioned in the article:

A general and efficient method for the highly enantioselective alkynylation of ketoimines through a zinc/1,1′-bi-2-naphthol (BINOL)-catalyzed process has been developed. A variety of ketoimines, including α-fluoroalkyl α-imine esters, α-aryl α-imine esters, and trifluoromethyl aryl ketoimines, are applicable and provide their corresponding quaternary propargyl amines in excellent yields with high ee values (up to 99 % ee). Both the steric and electronic effects of substituents at the 3,3′ positions of BINOL are critical for the reaction efficiency and enantioselectivity. To demonstrate the usefulness of the method, (R)-α-CF₃ α-proline has been prepared in a highly efficient manner. The notable features of this protocol are its broad substrate scope, high reaction efficiency (up to 99 %) and enantioselectivity (up to 99 % ee), low catalyst loading (5 mol % of BINOL derivative), and mild reaction conditions. This study involved multiple reactions and reactants, such as (R)-[1,3′:1′,1”:3”,1”’-Quaternaphthalene]-2′,2”-diol (cas: 851615-07-1Application In Synthesis of (R)-[1,3′:1′,1”:3”,1”’-Quaternaphthalene]-2′,2”-diol).

(R)-[1,3′:1′,1”:3”,1”’-Quaternaphthalene]-2′,2”-diol (cas: 851615-07-1) belongs to alcohols. A strong base can deprotonate an alcohol to yield an alkoxide ion (R―O−). For example, sodamide (NaNH2), a very strong base, abstracts the hydrogen atom of an alcohol. Under carefully controlled conditions, simple alcohols can undergo intermolecular dehydration to give ethers. This reaction is effective only with methanol, ethanol, and other simple primary alcohols.Application In Synthesis of (R)-[1,3′:1′,1”:3”,1”’-Quaternaphthalene]-2′,2”-diol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Proanthocyanidin B2 and transglutaminase synergistically improves gel properties of oxidized myofibrillar proteins was written by Zhang, Daojiu;Yang, Xu;Wang, Yichun;Wang, Biao;Wang, Shaoyu;Chang, Jinyang;Liu, Suwen;Wang, Hao. And the article was included in Food Chemistry in 2022.Computed Properties of C30H26O12 The following contents are mentioned in the article:

We investigated the roles of Proanthocyanidin B2 (PCB2) and transglutaminase (TGase) in improving myofibrillar protein (MP) gel properties. TGase and PCB2 increased the surface hydrophobicity (41%) and water holding capacity (WHC) (16%) of the MP. Secondary and tertiary structures of MP were resp. analyzed by Fourier transform IR spectroscopy (FTIR) and fluorescence spectrophotometry. The content of α -helix in MP was found to be increased while its fluorescence intensity decreased upon the addition of PCB2 and TGase. The addition of PCB2 and TGase resulted in formation of a dense MP network structure as revealed by SEM (SEM). Low-field NMR (LF-NMR) and magnetic resonance imaging (MRI) anal. showed that immobilized water levels in the MP gel were markedly increased while the amount of free water was significantly decreased after PCB2 and TGase addition These findings indicate that a combination of PCB2 and TGase are potential additives for meat products. This study involved multiple reactions and reactants, such as (2R,2’R,3R,3’R,4R)-2,2′-Bis(3,4-dihydroxyphenyl)-[4,8′-bichromane]-3,3′,5,5′,7,7′-hexaol (cas: 29106-49-8Computed Properties of C30H26O12).

(2R,2’R,3R,3’R,4R)-2,2′-Bis(3,4-dihydroxyphenyl)-[4,8′-bichromane]-3,3′,5,5′,7,7′-hexaol (cas: 29106-49-8) belongs to alcohols. Similar to water, an alcohol can be pictured as having an sp3 hybridized tetrahedral oxygen atom with nonbonding pairs of electrons occupying two of the four sp3 hybrid orbitals. The most common reactions of alcohols can be classified as oxidation, dehydration, substitution, esterification, and reactions of alkoxides.Computed Properties of C30H26O12

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Effect of inoculation method on the quality and nutritional characteristics of low-alcohol kiwi wine was written by Huang, Jintao;Wang, Yaqin;Ren, Yichen;Wang, Xingnan;Li, Hongcai;Liu, Zhande;Yue, Tianli;Gao, Zhenpeng. And the article was included in LWT–Food Science and Technology in 2022.Synthetic Route of C30H26O12 The following contents are mentioned in the article:

In order to prepare the kiwi wine with high nutritional characteristics and low alc. content, the physicochem. properties, organic acids, monomer phenols, water-soluble vitamins and aroma of kiwi wine fermented by Saccharomyces cerevisiae and Wickerhamomyces anomalus in different inoculation method were analyzed. The results showed that the alc. content of the three kiwi wines ranged from 5.3 to 5.5% (volume/volume). The lactic acid content of COF (inoculated with a mix of S. cerevisiae and W. anomalus) low-alc. kiwi wine was 10.99 mg/mL. The quercetin and catechin contents of WSF (sequential inoculation with W. anomalus followed by S. cerevisiae) low-alc. kiwi wine were significantly lower than those in the other kiwi wines. The aroma in COF and WSF low-alc. kiwi wines were predominately from W. anomalus, while those in SWF (sequential inoculation with S. cerevisiae followed by W. anomalus) low-alc. kiwi wine were predominately from S. cerevisiae. This study involved multiple reactions and reactants, such as (2R,2’R,3R,3’R,4R)-2,2′-Bis(3,4-dihydroxyphenyl)-[4,8′-bichromane]-3,3′,5,5′,7,7′-hexaol (cas: 29106-49-8Synthetic Route of C30H26O12).

(2R,2’R,3R,3’R,4R)-2,2′-Bis(3,4-dihydroxyphenyl)-[4,8′-bichromane]-3,3′,5,5′,7,7′-hexaol (cas: 29106-49-8) belongs to alcohols. Alcohols are weak acids. The most acidic simple alcohols (methanol and ethanol) are about as acidic as water, and most other alcohols are somewhat less acidic. Secondary alcohols are easily oxidized without breaking carbon-carbon bonds only as far as the ketone stage. No further oxidation is seen except under very stringent conditions.Synthetic Route of C30H26O12

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Alleviation of postharvest rib-edge darkening and chilling injury of carambola fruit by brassinolide under low temperature storage was written by Duan, Wenhui;Ngaffo Mekontso, Francine;Li, Wen;Tian, Jixin;Li, Jiangkuo;Wang, Qing;Xu, Xiangbin. And the article was included in Scientia Horticulturae (Amsterdam, Netherlands) in 2022.Category: alcohols-buliding-blocks The following contents are mentioned in the article:

Carambola fruit produced in the tropical and subtropical region could easily suffer the postharvest loss in low temperature storage and cold chain logistics owing to the hazard of chilling injury (CI). Here, the effects of brassinolide (BR) on phenolic metabolism, rib-edge darkening and CI of carambola fruit were studied. The present results showed that BR treatment effectively delayed the CI and weight loss, maintained peel color and flesh firmness, and inhibited the increases of electrolyte leakage, malondialdehyde and reactive oxygen species production, induced total phenols and proline accumulation. Moreover, BR treatment raised the activities of antioxidant enzymes and higher content of individual phenolic compounds, inhibited membrane lipid peroxidation and safeguard cellular membrane integrity. This study for the first time demonstrated that BR could alleviate CI in carambola fruit during low temperature storage and cold chain circulation. This study involved multiple reactions and reactants, such as (2R,2’R,3R,3’R,4R)-2,2′-Bis(3,4-dihydroxyphenyl)-[4,8′-bichromane]-3,3′,5,5′,7,7′-hexaol (cas: 29106-49-8Category: alcohols-buliding-blocks).

(2R,2’R,3R,3’R,4R)-2,2′-Bis(3,4-dihydroxyphenyl)-[4,8′-bichromane]-3,3′,5,5′,7,7′-hexaol (cas: 29106-49-8) belongs to alcohols. A strong base can deprotonate an alcohol to yield an alkoxide ion (R―O−). For example, sodamide (NaNH2), a very strong base, abstracts the hydrogen atom of an alcohol. Grignard and organolithium reagents are powerful tools for organic synthesis, and the most common products of their reactions are alcohols.Category: alcohols-buliding-blocks

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Phenolic-rich feijoa extracts from flesh, peel and whole fruit activate apoptosis pathways in the LNCaP cell line was written by Peng, Yaoyao;Bishop, Karen Suzanne;Ferguson, Lynnette Robin;Quek, Siew Young. And the article was included in Food Chemistry in 2022.Product Details of 29106-49-8 The following contents are mentioned in the article:

This study aimed to explore the potential anticancer activity of phenolic-rich feijoa extracts from the flesh, peel, and whole fruit on the human prostate cancer cell line (LNCaP). Results showed that feijoa extracts had cancer-specific anti-proliferative activity on the LNCaP cell line. The anticancer activity of feijoa extracts was shown through activation of the caspase-dependent apoptosis pathway based on the increase of sub-G1 phase in the cell cycle, the decrease of mitochondrial membrane potential, as well as the elevated caspase 3, 8, and 9 activity in the treated LNCaP cells. The anti-cancer activity of feijoa extracts could be attributed to the high total phenolic contents (0.14-0.37 mg GAE/mg dw) and, in particular, the high ellagic acid content (2.662-9.119μg/mg dw). The successful activation of the caspase-dependent apoptosis pathway indicates that phenolic-rich feijoa extracts have a good potential to be utilized as a functional ingredient in foods and nutraceuticals. This study involved multiple reactions and reactants, such as (2R,2’R,3R,3’R,4R)-2,2′-Bis(3,4-dihydroxyphenyl)-[4,8′-bichromane]-3,3′,5,5′,7,7′-hexaol (cas: 29106-49-8Product Details of 29106-49-8).

(2R,2’R,3R,3’R,4R)-2,2′-Bis(3,4-dihydroxyphenyl)-[4,8′-bichromane]-3,3′,5,5′,7,7′-hexaol (cas: 29106-49-8) belongs to alcohols. A strong base can deprotonate an alcohol to yield an alkoxide ion (R―O−). For example, sodamide (NaNH2), a very strong base, abstracts the hydrogen atom of an alcohol. Converting an alcohol to an alkene requires removal of the hydroxyl group and a hydrogen atom on the neighbouring carbon atom. Dehydrations are most commonly carried out by warming the alcohol in the presence of a strong dehydrating acid, such as concentrated sulfuric acid.Product Details of 29106-49-8

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts