Tag: 300-400

Hatairaktham, Suneerat;Masaratana, Patarabutr;Hantaweepant, Chattree;Srisawat, Chatchawan;Sirivatanauksorn, Vorapan;Siritanaratkul, Noppadol;Panichkul, Narumol;Kalpravidh, Ruchaneekorn W. published 《Curcuminoids supplementation ameliorates iron overload, oxidative stress, hypercoagulability, and inflammation in non-transfusion-dependent β-thalassemia/Hb E patients》 in 2021. The article was appeared in 《Annals of Hematology》. They have made some progress in their research.Recommanded Product: 119-47-1 The article mentions the following:

Curcuminoids, polyphenol compounds in turmeric, possess several pharmacol. properties including antioxidant, iron-chelating, and anti-inflammatory activities. Effects of curcuminoids in thalassemia patients have been explored in a limited number of studies using different doses of curcuminoids. The present study aims to evaluate the effects of 24-wk curcuminoids supplementation at the dosage of 500 and 1000 mg/day on iron overload, oxidative stress, hypercoagulability, and inflammation in non-transfused β-thalassemia/Hb E patients. In general, both curcuminoids dosages significantly lowered the levels of oxidative stress, hypercoagulability, and inflammatory markers in the patients. In contrast, reductions in iron parameter levels were more remarkable in the 1000 mg/day group. Subgroup anal. revealed that a marker of hypercoagulability was significantly decreased only in patients with baseline ferritin ≤ 1000 ng/mL independently of curcuminoids dosage. Moreover, the alleviation of iron loading parameters was more remarkable in patients with baseline ferritin > 1000 ng/mL who receive 1000 mg/day curcuminoids. On the other hand, the responses of oxidative stress markers were higher with 500 mg/day curcuminoids regardless of baseline ferritin levels. Our study suggests that baseline ferritin levels should be considered in the supplementation of curcuminoids and the appropriate curcuminoids dosage might differ according to the required therapeutic effect. The experimental procedure involved many compounds, such as 2,2-Methylenebis(6-tert-butyl-p-cresol) (cas: 119-47-1) .

Recommanded Product: 119-47-12,2′-Methylenebis(4-methyl-6-tert-butylphenol)(CAS: 119-47-1) is a natural product found in Streptomyces and Aspergillus fumigatus .

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Formula: C23H32O2《Comparative analysis of volatile profiles in four pine-mushrooms using HS-SPME/GC-MS and E-nose》 was published in 2022. The authors were Guo, Qiyong;Adelina, Nadya Mara;Hu, Jintao;Zhang, Ligang;Zhao, Yuhong, and the article was included in《Food Control》. The author mentioned the following in the article:

Pine-mushrooms is rich in bioactive compounds, possess a unique aroma profile for culinary art. In China, pine-mushroom has been produced in Southwest and Northeast area. However, the discrepancy of volatile profiles in pine-mushrooms from two regions was unclear due to different extraction and detection method applied in research. This study attempted to compare the volatile profiles of four pine-mushrooms from Southwest (LS) and Northeast (HEB, SY, MDJ) using Headspace Solid Phase Microextraction coupled with Gas Chromatog. Mass Spectrometry (HS-SPME/GC-MS) and Electronic nose (E-nose). showed a significant difference in aroma profiles among samples. A total of 100 volatile compounds were identified, and separated into 11 classes. Benzaldehyde and hexanal were detected in all samples, which could be the pivotal aroma components in pine-mushrooms. Aromatic components, were present in LS pine-mushroom from Southwest China, including abundant of Me (Z)-N-hydroxybenzenecarboximidate, benzaldehyde, and Me 3-phenylprop-2-enoate. Meanwhile, some alcs. (such as oct-1-en-3-ol, hexan-1-ol) were characteristic compounds present in HEB, SY and MDJ samples. Principal component anal. (PCA) of E-nose data showed a clear distinction among samples. In addition, this study also highlighted the correlation between key volatile compounds detected by GC-MS and E-nose sensors, which could be benefit for further explanation to the origin of differences in sensory quality of pine-mushrooms. The experimental procedure involved many compounds, such as 2,2-Methylenebis(6-tert-butyl-p-cresol) (cas: 119-47-1) .

Formula: C23H32O22,2′-Methylenebis(4-methyl-6-tert-butylphenol)(CAS: 119-47-1) is a natural product found in Streptomyces and Aspergillus fumigatus .

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Grand, Caroline;Cogen, Jeffrey M.;Wills, Scott T. published 《Stability of phenolic antioxidants in the presence of sulfonic acid: model compound studies for moisture-crosslinked polyethylene》. The research results were published in《Polymer Degradation and Stability》 in 2021.Formula: C23H32O2 The article conveys some information:

Alkoxysilane-functionalized polyethylene can be crosslinked in the presence of acid catalysts, including Bronsted acids, to yield durable pipe and cable insulation materials. To provide guidelines for the selection of stable phenolic antioxidants in the presence of Bronsted acids, reactions of 4 model alkylphenol compounds in the presence of p-dodecylbenzenesulfonic acid (DBSA) in dodecane were studied as a solution model for polyethylene-based systems. The results point to increasing stability towards DBSA of phenolic compounds when: (i) alkyl groups have less substitution (tertiary carbon compared to quaternary carbon), (ii) they have alkyl-substitution in the para position, and (iii) they have a reduced number of alkyl substituents around the phenol ring. Antioxidants with alkyl or isocyanurate bridges had reaction rates comparable to butylated hydroxytoluene (BHT) and followed the trend outlined in model alkylphenols. The sulfur-bridged antioxidant stood out as rapidly consumed under the reaction conditions. Therefore, selection of phenolic antioxidants for formulations containing strong Bronsted acids should generally favor phenolic compounds with alkyl-substituted para positions and limited number of alkyl substituents in non-para positions, and without quaternary carbon substituents. Moreover, stability of alternate sulfur-containing antioxidants should be assessed if used with sulfonic acids, given the rapid decomposition of the sulfur-bridged antioxidant observed in this work. And 2,2-Methylenebis(6-tert-butyl-p-cresol) (cas: 119-47-1) was used in the research process.

Formula: C23H32O22,2′-Methylenebis(4-methyl-6-tert-butylphenol)(CAS: 119-47-1) is a natural product found in Streptomyces and Aspergillus fumigatus .

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Cao, Bili;Lv, Xue;Chen, Zijing;Xu, Kun published 《Supplementing green light under strong sunlight improves growth and functional ingredients of ginger (Zingiber officinale Rosc.) in summer》 in 2021. The article was appeared in 《Industrial Crops and Products》. They have made some progress in their research.Electric Literature of C23H32O2 The article mentions the following:

The green light for ginger growth may not be as unimportant as often assumed, but still now the roles of green light in ginger remain poorly understood. To investigate this issue, the ‘Shandong Number 1’ginger cultivar was grown and treated with two contrasting light environments: sunlight (CK treatment), supplementing green light under strong sunlight (T1 treatment), and this study explored morphol. alterations, photosynthetic responses and gene expression of ginger in response to supplementing green light under strong sunlight, based on ginger’s own species characteristics. The results showed as follows. One hand, supplementing green light under strong sunlight promoted expression of gibberellin biosynthesis gene and altered the morphol. characteristics of ginger. In response to supplementing green light under strong sunlight, ginger presented not only shade avoidance symptoms characteristics, but also promotion of number of shoots, and thus rendered higher crown d. and greater crown volume When exposed to supplementing green light under strong sunlight condition, the strategies implemented by ginger to deal with stem elongation and branching increase seemed to be a species-specific response. On the other hand, the pos. effect of supplementing green light under strong sunlight on ginger also depends on the growth conditions. Previous research confirmed that ginger did not grow well under green light only treatment. In contrast, supplementing green light under strong sunlight resulted in higher crown d. and greater crown volume, which played a role in shading for the inner leaves and young pseudostems under summer sunlight, although strong summer light posed a threat to ginger growth. In addition, supplementing green light under strong sunlight led to upregulation of chlorophyll metabolism gene and an increase in Chlorophyll a content. Also, the enhancement of green light radiation effectively increased expressions of photosynthetic genes and photosynthesis rate. These all contributed to the improvement of photosynthetic efficiency of ginger leaves, as a way to increase light energy consumption, and thus reduced chloroplast senescence caused by excess light energy in summer. Furthermore, higher photosynthesis rate contributed to accumulation of photosynthetic products, and supported the material requirements for increasing biomass and improving rhizome functional ingredients. Taken together, this study will lay the foundations of a better understanding of the importance of green light to ginger. To complete the study, the researchers used 2,2-Methylenebis(6-tert-butyl-p-cresol) (cas: 119-47-1) .

Electric Literature of C23H32O22,2′-Methylenebis(4-methyl-6-tert-butylphenol)(CAS: 119-47-1) is a natural product found in Streptomyces and Aspergillus fumigatus .

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Safety of 2,2-Methylenebis(6-tert-butyl-p-cresol)In 2020, Gautier, Francoise;Tourneix, Fleur;Assaf Vandecasteele, Hind;van Vliet, Erwin;Bury, Dagmar;Alepee, Nathalie published 《Read-across can increase confidence in the Next Generation Risk Assessment for skin sensitisation: A case study with resorcinol》. 《Regulatory Toxicology and Pharmacology》published the findings. The article contains the following contents:

Historically skin sensitization risk assessment for cosmetic ingredients was based on animal models, however regulatory demands have led to Next Generation Risk Assessment (NGRA), using data from New Approach Methodologies (NAM) and Defined Approaches (DA). This case study was meant to investigate if the use of resorcinol at 0.2% in a face cream was safe and a maximum use concentration could be defined. The NAM data and DA predictions could not provide sufficient confidence to determine a point of departure (POD). Therefore, the application of read-across was explored to increase the level of confidence. Analog searches in various tools and databases using “mode of action” and “chem. structural features” retrieved 535 analogs. After refinement by excluding analogs without a defined structure, similar reactivity profile and skin sensitization data, 39 analogs remained. A final selection was made based on three approaches: expert judgment, chem. similarity or Local Lymph Node Assay data (LLNA). All read-across approaches supported a moderate potency. A POD derived from the LLNA EC3 of 3.6% was determined leading to a favorable NGRA conclusion and a maximum use concentration of 0.36%. This was supported by a traditional risk assessment based on the available animal data for resorcinol. And 2,2-Methylenebis(6-tert-butyl-p-cresol) (cas: 119-47-1) was used in the research process.

Safety of 2,2-Methylenebis(6-tert-butyl-p-cresol)2,2′-Methylenebis(4-methyl-6-tert-butylphenol)(CAS: 119-47-1) is a natural product found in Streptomyces and Aspergillus fumigatus .

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Ma, Xue-feng;Ru, Chao;Liu, Yu-qing;Song, Xue;Lu, Zhou-min published 《Ultrasonic-assisted solvent extraction of essential oil and main components of Citrus reticulata Blanco cv. Manau Gan》. The research results were published in《Shipin Yanjiu Yu Kaifa》 in 2021.Quality Control of 2,2-Methylenebis(6-tert-butyl-p-cresol) The article conveys some information:

The extraction solvent and material-liquid ratio were selected to optimize the essential oil extraction process of Citrus reticulata Blanco cv. Manau Gan. Results showed that the most suitable solvent for the essential oil extraction of Citrus reticulata Blanco cv. Manau Gan was petroleum ether, with a material-to-liquid ratio of 1:15 (g/mL). Three factors-ultrasonic time, temperature, and power were selected for a single-factor experiment An orthogonal condition optimization experiment was carried out for the ultrasonic extraction parameters of the essential oil of Citrus reticulata Blanco cv. Manau Gan. The optimization results were as follows: ultrasound time, 120 min; ultrasound temperature, 50 °C; and ultrasonic power, 60 W. The essential oil extraction rate of Citrus reticulata Blanco cv. Manau Gan reached 2.47% under these conditions. A total of 19 compounds were identified from the essential oil of Citrus reticulata Blanco cv. Manau Gan by gas chromatog.-mass spectrometry analyses, accounting for 97.60% of total volatiles. Thus, the optimized process could be used to extract the essential oil of Citrus reticulata Blanco cv. Manau Gan. And 2,2-Methylenebis(6-tert-butyl-p-cresol) (cas: 119-47-1) was used in the research process.

Quality Control of 2,2-Methylenebis(6-tert-butyl-p-cresol)2,2′-Methylenebis(4-methyl-6-tert-butylphenol)(CAS: 119-47-1) is a natural product found in Streptomyces and Aspergillus fumigatus .

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Wang, Yali;Yang, Lu;Zhang, Ke;Chen, Xiaoxiang;Wang, Hangyu;Cheng, Ping;Wang, Jinhui published 《Untargeted metabolomics analysis of different grape varieties and different parts of wine grape using gas chromatography and mass spectrometry technique》. The research results were published in《Journal of Biobased Materials and Bioenergy》 in 2021.Name: 2,2-Methylenebis(6-tert-butyl-p-cresol) The article conveys some information:

Natural active compounds are an important key to the development and utilization of functional foods and medicine. In this study, the chem. diversity and varietal differences of wine grape were studied by using the untargeted metabolomics method based on gas chromatog.-mass spectrometry (GC-MS), and the secondary metabolites of different cultivars and different parts were analyzed. A GC-MS-based metabolomic approach and chemometrics tools was used to identify potential active compounds in Vitis vinifera. The results showed that the content of active compounds in red wine varieties was higher than that in white wine varieties, and the content of active ingredients in grape seeds was significantly higher than that in fruits. In conclusion, this study analyzed the metabolite composition and differentiation of different wine grape fruits in Turpan as a whole, and is expected to lay a foundation for the study of wine grape and to provide a theor. basis for development and utilization of the Dietary supplement and medicine on them. And 2,2-Methylenebis(6-tert-butyl-p-cresol) (cas: 119-47-1) was used in the research process.

Name: 2,2-Methylenebis(6-tert-butyl-p-cresol)2,2′-Methylenebis(4-methyl-6-tert-butylphenol)(CAS: 119-47-1) is a natural product found in Streptomyces and Aspergillus fumigatus .

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Brzic, Sasa;Kovacevic, Nemanja;Grzetic, Jelena;Bogosavljevic, Marica;Mijatov, Slavko;Bogdanov, Jovica;Kovacevic, Tihomir published 《Multi-component elastomeric composites based on castor oil/AgI/KI for cloud seeding: processing and modeling of reagent efficiency》 in . The article was appeared in 《Polymer Bulletin (Heidelberg, Germany)》. They have made some progress in their research.Product Details of 119-47-1 The article mentions the following:

This study involves the development of sustainable technol./methodol. for the production, characterization and numerical calculation of highly effective multi-component anti-hail seeding reagents (seeding composites) based on silver iodide and iodide of an alkali metal, homogenized in synthetic or bio polyurethane binder. Polyurethane-based seeding composites are produced via casting method and the results of uniaxial tensile tests, hardness and dynamic-mech. anal. show that applied technique is more suitable compared to the conventional dry homogenization of the seeding active agents. Lower viscosity, uniform powd. seeding agents distribution and improved mech. properties, e.g. higher tensile strength (5.05 MPa) and Shore A hardness (89 ShA) are achieved using castor oil as bio-polymer binder, compared to the synthetic polymer hydroxyl terminated poly(butadiene). In addition, significantly higher glass transition temperature obtained for seeding composite with castor oil as polymer binder indicating higher d. and branched polymer network. Numerical models of the convective clouds are used to determine composition and mass of seeding agent which gives the best results concerning hail suppression or rain intensification. Results show that composite seeding reagents which contain silver iodide and potassium iodide in a molar ratio of 1:2 upon combustion generate freezing nuclei which are active above 0 °C, providing the most effective cloud seeding with 10.53% hail accumulations suppression. And 2,2-Methylenebis(6-tert-butyl-p-cresol) (cas: 119-47-1) was used in the research process.

Product Details of 119-47-12,2′-Methylenebis(4-methyl-6-tert-butylphenol)(CAS: 119-47-1) is a natural product found in Streptomyces and Aspergillus fumigatus .

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Wang, Peng;Wang, Junjie;Zhang, Huaiyu;Wang, Cong;Zhao, Lunaike;Huang, Ting;Qing, Ken published 《Chemical Composition, Crystal Morphology, and Key Gene Expression of the Cuticular Waxes of Goji (Lycium barbarum L.) Berries》. The research results were published in《Journal of Agricultural and Food Chemistry》 in 2021.Category: alcohols-buliding-blocks The article conveys some information:

The cuticular wax of fruit is closely related to quality, storability, and pathogen susceptibility after harvest. However, little is known about the cuticular wax of goji berry (Lycium barbarum L.) cultivars. In the present study, the chem. composition, crystal structures, and expression levels of associated genes of the cuticular wax of six goji cultivars were investigated. We detected 70 epicuticular wax compounds in six goji cultivars. Among them, fatty acids, alkanes, and primary alcs. were the major components of the cuticular wax of goji berries, which were related to the formation of irregular lamellar crystal structures. The terpenoid compounds in the cuticular wax of goji berries were highly resistant to Alternaria rot. Moreover, the CER1, CER6, LACS1, MAH1, LTP4, ABC11, MYB96, and WIN1 genes in goji berries might be closely related to wax synthesis. These results provide valuable information for breeding and screening goji cultivars suitable for postharvest storage. To complete the study, the researchers used 2,2-Methylenebis(6-tert-butyl-p-cresol) (cas: 119-47-1) .

Category: alcohols-buliding-blocks2,2′-Methylenebis(4-methyl-6-tert-butylphenol)(CAS: 119-47-1) is a natural product found in Streptomyces and Aspergillus fumigatus .

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Application In Synthesis of 2,2-Methylenebis(6-tert-butyl-p-cresol)《Analysis of the volatile components of Polygonum chinense L. extracted with different solvents by GC-MS》 was published in 2021. The authors were Wei, Anda;Zhu, Hua;Xie, Fengfeng;Zhang, Miao;Huang, Piaoiing;Yang, Wenqi, and the article was included in《Agricultural Biotechnology》. The author mentioned the following in the article:

This study was conducted to investigate the volatile components of Polygonum chinense L. The volatile components of the methanol extract, Et acetate extract, chloroform extract and petroleum ether extract of P. chinense were analyzed and determined by gas chromatog. The volatile components of the methanol extract from P. chinense were the most, and phenolic acids and ketones accounted for a relatively high proportion, among which pyrogallic acid had the highest content. The Et acetate extract contained the second most volatile components, mostly acids and esters, of which ss-sitosterol had the highest content; the chloroform and petroleum ether extracts had relatively few types of volatile components, most of which were alkanes, and the content of -sitosterol shared by the two was the highest. The common substances of the four extracts were palmitic acid and phytol. This study provides a theor. basis for the quality evaluation of P. chinense and a scientific basis for its resource development. And 2,2-Methylenebis(6-tert-butyl-p-cresol) (cas: 119-47-1) was used in the research process.

Application In Synthesis of 2,2-Methylenebis(6-tert-butyl-p-cresol)2,2′-Methylenebis(4-methyl-6-tert-butylphenol)(CAS: 119-47-1) is a natural product found in Streptomyces and Aspergillus fumigatus .

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