Tag: 300-400

Related Products of 119-47-1In 2021, Sicar, Milica Rankov;Micic, Radoslav;Tomic, Milan;Durisic-Mladenovic, Natasa published 《Efficiency of different additives in the improvement of the oxidation stability of fatty acid methyl esters with different properties》. 《Journal of the Serbian Chemical Society》published the findings. The article contains the following contents:

This study evaluates six formulations in improving the oxidation stability of different fatty acid Me esters (MEs). Two MEs differed in the unsaturation levels as they were synthesized from different feedstock: a blend of soybean and sunflower oils, and waste cooking oil; they did not fulfill the requirements of the EN 14214 standard concerning their oxidation stability (≈0.6 h) and some impurities. The third MEs (SoSuME-EN) were fully compliant with the standard Five formulations were phenolic-based, containing single or mixed antioxidant compounds of different mol. structures; one was amine-based. Different dosages of the formulations were added to the ME samples (corresponding to the addition range 50-48300 ppm). The MEs stability expressed as induction periods, IP, determined by the Rancimat method, were used for the calculation of stabilization factors, SF, indicating the efficiency of the applied formulation. The formulation containing 2-(1,1-dimethyl-ethyl)-1,4-benzenediol was the most efficient concerning the lowest consumption rate and the highest SF achieved for the low quality ME. 2,2′-Methylene-bis-(4-methyl-6-tert-butylphenol) was linked with higher antioxidant potency than the amine-based formulation and the phenolic compounds with two bulky tert-Bu groups. Among the 4 selected phenolic additives, butylated hydroxytoluene and 2,2′-methylene-bis-(4-methyl-6-tert-butylphenol) had similar efficiency in SoSuME-EN (at ≈500 ppm they produced SF ≈ 2), while it took twice of this amount for mixed butylphenols to achieve the same effect. The experimental procedure involved many compounds, such as 2,2-Methylenebis(6-tert-butyl-p-cresol) (cas: 119-47-1) .

Related Products of 119-47-12,2′-Methylenebis(4-methyl-6-tert-butylphenol)(CAS: 119-47-1) is a natural product found in Streptomyces and Aspergillus fumigatus .

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Jiang, Haifeng;Liu, Haipeng;Liu, Baolin;Zhang, Yu;Li, Shu;Chen, Jie published 《Effect of Cellulose-Lignin Interactions on Catalytic Pyrolysis over Formate Salt Catalysts》 in 2021. The article was appeared in 《ACS Sustainable Chemistry & Engineering》. They have made some progress in their research.HPLC of Formula: 119-47-1 The article mentions the following:

This work studied the effect of cellulose-lignin interactions under potassium formate (HCOOK) and nickel formate (Ni(HCOO)₂) on behavior and product distributions. The results indicated that the presence of HCOOK affected the whole thermal decomposition process, while the effect of Ni(HCOO)₂ was mainly manifested before 339°C. The interaction under the action of HCOOK favored the generation of carbonyl compounds, and the catalytic pyrolysis with Ni(HCOO)₂ was better for formating phenols. The high peak intensities of CO and CH₄ were achieved by adding nickel formate and potassium formate, resp. It was obviously different from noncatalytic pyrolysis. The evolution of a char structure further revealed that different formate salts had different effects on the interactions. The statistical method according to the distribution of the liquid component confirmed that HCOOK had the strongest effect for reducing the cellulose-lignin interactions. To complete the study, the researchers used 2,2-Methylenebis(6-tert-butyl-p-cresol) (cas: 119-47-1) .

HPLC of Formula: 119-47-12,2′-Methylenebis(4-methyl-6-tert-butylphenol)(CAS: 119-47-1) is a natural product found in Streptomyces and Aspergillus fumigatus .

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Du, Bibai;Li, Quan;Pan, Zibin;Zhang, Yun;Xie, Ruiman;Luo, Dan;Zeng, Lixi published 《Improved LC-MS/MS Method for the Simultaneous Determination of Synthetic Phenol Antioxidants and Relevant Metabolites Making Use of Atmospheric Pressure Chemical Ionization and a Trap Column》 in 2021. The article was appeared in 《Environmental Science & Technology Letters》. They have made some progress in their research.Synthetic Route of C23H32O2 The article mentions the following:

The prevalently used LC-MS/MS methods for the simultaneous determination of synthetic phenol antioxidants (SPAs) and relevant metabolites suffer from a serious drawback of low sensitivity for 2,6-di-tert-butyl-4-hydroxytoluene (BHT) and a common issue of background contamination, which hampers the simple and accurate detection of these substances at trace levels in environmental samples. In this study, we developed an improved LC-MS/MS method for the simultaneous determination of eight SPAs and four relevant metabolites, including BHT. By use of atm. pressure chem. ionization (APCI), the sensitivity of BHT in the LC-MS/MS was enhanced approx. 260 times vs. results obtained by using electrospray ionization (ESI), which allowed the anal. of BHT up to 1.1 ng/g in indoor dust and 0.06 ng/g in human plasma. Similarly, the sensitivity of 2,4,6-tri-tert-butylphenol and 2,6-di-tert-butyl-4-sec-butylphenol was also enhanced with APCI, which avoided their sep. anal. by GC-MS. By installation of a C₁₈ column after the eluent mixer and before the injector as a trap column, the target analytes leached out from the LC system were eluted at a much later retention time than those in the samples, which resulted in complete elimination of the instrumental background contamination. These improvements enable the method to be well applied to the real samples. The experimental procedure involved many compounds, such as 2,2-Methylenebis(6-tert-butyl-p-cresol) (cas: 119-47-1) .

Synthetic Route of C23H32O22,2′-Methylenebis(4-methyl-6-tert-butylphenol)(CAS: 119-47-1) is a natural product found in Streptomyces and Aspergillus fumigatus .

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Related Products of 119-47-1In 2022, Liyanage, D. S.;Omeka, W. K. M.;Sandamalika, W. M. Gayashani;Udayantha, H. M. V.;Jeong, Taehyug;Lee, Sukkyoung;Lee, Jehee published 《PDI family thioredoxin from disk abalone (Haliotis discus discus): Responses to stimulants (PAMPs, bacteria, and viral) and functional characterization》. 《Fish & Shellfish Immunology》published the findings. The article contains the following contents:

Thioredoxin, a highly conserved class of proteins involved in redox signaling, is found in a range of organisms from bacteria to higher-level eukaryotes. Thioredoxin acts as an active regulatory enzyme to eliminate excessive reactive oxygen species, thereby preventing cellular damage. In this study, the cDNA sequence of thioredoxin domain-containing 5 (AbTXNDC5) from the disk abalone transcriptomic database was characterized. An in silico anal. of AbTXNDC5 was performed, and its spatial and temporal expression patterns in hemocytes and gills in response to bacteria (Vibrio parahaemolyticus, Listeria monocytogenes), viral hemorrhagic septicemia virus, and pathogen-associated mol. pattern mols. were observed Furthermore, AbTXNDC5 expression was examined in different developmental stages. Functional assays to explore insulin disulfide reduction, anti-apoptotic activity, and protection against hypoxic cell death of AbTXNDC5 were conducted through recombinant proteins or overexpression in cells. AbTXNDC5 contains a 1179-bp open reading frame coding for 392 amino acids. Conserved thiol-disulfide cysteine residues within two Cys-X-X-Cys motifs were found in AbTXNDC5. Quant. real-time polymerase chain reaction indicated that healthy digestive tract and hemocyte tissues expressed high levels of AbTXNDC5 mRNA, which may protect the host from invading pathogens. Immune-challenged abalone hemocytes and gills exhibited upregulated expression of AbTXNDC5 at different time points. rAbTXNDC5 also exhibited a functional insulin disulfide reductase activity. AbTXNDC5 conferred protection to cultured cells from apoptosis and hypoxia-induced stress, compared to the pcDNA3.1(+) transfected control cells. Therefore, AbTXNDC5 can be considered an important gene in abalones in relation to the primary immune system and regulation of redox homeostasis and confers protection from stress. To complete the study, the researchers used 2,2-Methylenebis(6-tert-butyl-p-cresol) (cas: 119-47-1) .

Related Products of 119-47-12,2′-Methylenebis(4-methyl-6-tert-butylphenol)(CAS: 119-47-1) is a natural product found in Streptomyces and Aspergillus fumigatus .

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Song, Kai;Ren, Xu;Zhang, Qiaoyun;Xu, Linghan;Liu, Dan published 《Electrochemical treatment for leachate membrane retentate: Performance comparison of electrochemical oxidation and electro-coagulation technology》. The research results were published in《Chemosphere》 in 2022.HPLC of Formula: 119-47-1 The article conveys some information:

With the widespread use of membrane in advanced treatment of leachate, China produces a large amount of leachate membrane retentate (LMR) (23.4 million tons) annually, which is usually treated by incineration or recirculation in engineering, but these technologies have many drawbacks. LMR is suitable for electrochem. treatment due to its high elec. conductivity This study compared the performances of electrochem. oxidation (EO) and electro-coagulation (EC) technol. on LMR treatment under different exptl. conditions, including anode material, c.d., initial pH and reaction time. We found that EO optimal conditions achieved 70.1%, 83.1%, 78.7%, 98.7%, and 69.7% removal of total organic carbon (TOC), UV absorption (at 254 nm), chromaticity, ammonia nitrogen (NH₃-N), and total nitrogen (TN), resp. Compared with EO, EC exhibited a similar removal ability for organics and better removals of chroma, but much less performance for removing nitrogen pollutants in the same reaction time, i.e., removals of NH₃-N and TN were only 31.5% and 36.2%, resp. Meanwhile, EC showed much higher instantaneous current efficiency of COD than EO under its optimal reaction time (120 min). In addition, the UV-Vis spectra and 3D fluorescence spectra indicated that EO exhibited relatively outstanding performance in decomposing dissolved organic matter (DOM) with rather complicated structures than EC. Also, the flow field-flow fractionation technique demonstrated that EO preferentially destroy humic-like, large mol. weight DOM, and converting them to smaller mols., which resulted in more volatile organic compounds in EO samples than EC samples. While EC had little selectivity in the removal of organics, except humic-like DOM with relative small mol. These findings can provide a theor. basis for the electrochem. treatment of LMR. And 2,2-Methylenebis(6-tert-butyl-p-cresol) (cas: 119-47-1) was used in the research process.

HPLC of Formula: 119-47-12,2′-Methylenebis(4-methyl-6-tert-butylphenol)(CAS: 119-47-1) is a natural product found in Streptomyces and Aspergillus fumigatus .

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Ai, Zhengdong;Ma, Chong;Wan, Ruiming;Yin, Jingyi;Li, Guiming;Li, Yan;Chen, Li published 《Anticancer Activity and Molecular Mechanism of Momordica cochinchinensis Seed Extract in Chronic Myeloid Leukemia Cells》 in 2022. The article was appeared in 《Nutrition and Cancer》. They have made some progress in their research.Related Products of 119-47-1 The article mentions the following:

Targeting Bcr-Abl is the key to the treatment of chronic myeloid leukemia. Despite great progress in the treatment of patients with chronic CML, advanced CML patients are still unable to obtain effective and safe drugs. Momordica cochinchinensis seed is the dried ripe seed of Momordica cochinchinensis, which is a kind of fruit and consumed for dietary as well as medicinal uses. This study aimed to investigate the anticancer activity of Momordica cochinchinensis seed extract (MCSE) in CML cells. CML cells (KBM5 and KBM5-T315I) were treated with MCSE and analyzed for growth, apoptosis, and signal transduction. Nude mouse xenograft model was used to evaluate the antitumor activity of MCSE In Vivo. MCSE significantly reduced the cell viability of CML cells, triggered G0/G1 phase arrest in KBM5 cells and S phase arrest in KBM5-T315I cells. Concurrently, MCSE caused the activation of caspase-3, -8, -9, PARP and the degradation of Mcl-1, ultimately triggering endogenous and exogenous cell apoptosis. Meanwhile, MCSE downregulated Bcr-Abl levels and its downstream signaling pathways. Addnl., MCSE inhibited the growth of CML cells in nude mouse xenografts. Taken together, this study demonstrated the anticancer mechanism of MCSE, namely blocking Bcr-Abl and downregulating Mcl-1, and finally induced apoptosis of CML cells. The experimental procedure involved many compounds, such as 2,2-Methylenebis(6-tert-butyl-p-cresol) (cas: 119-47-1) .

Related Products of 119-47-12,2′-Methylenebis(4-methyl-6-tert-butylphenol)(CAS: 119-47-1) is a natural product found in Streptomyces and Aspergillus fumigatus .

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Wu, Fanglan;Wei, Qiusi;Yang, Mei;Deng, Rongyan;Liu, Shinan published 《Analysis of chemical components in two tree species of magnoliaceae, Magnolia sumatrana var. glauca (Blume) Figlar & Noot and Magnolia hypolampra (Dandy) Figlar》 in . The article was appeared in 《Natural Product Research》. They have made some progress in their research.Reference of 2,2-Methylenebis(6-tert-butyl-p-cresol) The article mentions the following:

The essential oils from roots, branches, leaves and bark of Magnolia sumatrana var. glauca (Blume) Figlar & Noot and Magnolia hypolampra (Dandy) Figlar were extracted by ultrasonic-assisted extraction and the chems. were determined by gas chromatog.-mass spectroscopy (GC-MS). The major constitutes of M. sumatrana var. glauca were trans-cinnamaldehyde (27.55%), caryophyllene (1.20-10.14%), (+)-bulnesol (9.70%), α-caryophyllene (2.35-6.35%), α-eudesmol (1.08-6.17%). M. hypolampra was characterized by the presence of safrole (0.18-35.01%), (+) cycloisosativene (18.70%), oxirane, hexadecyl- (0.72-12.79%), β-cubebene (1.53-8.90%), (Z)-14-tricosenyl formate (8.65%). This is the first study of the composition of essential oils from the roots, branches and bark of M. sumatrana var. glauca and the roots of M. hypolampra, and some compounds were being described for the first time. Combined with present results and literatures, phytochems. may be affected by multi-factors such as organs, growing location, and extraction methods, providing more approaches for further exploration of the non-wood resources of forestry species. To complete the study, the researchers used 2,2-Methylenebis(6-tert-butyl-p-cresol) (cas: 119-47-1) .

Reference of 2,2-Methylenebis(6-tert-butyl-p-cresol)2,2′-Methylenebis(4-methyl-6-tert-butylphenol)(CAS: 119-47-1) is a natural product found in Streptomyces and Aspergillus fumigatus .

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Application In Synthesis of 2,2-Methylenebis(6-tert-butyl-p-cresol)《Extracts of endophytic fungi from leaves of selected Nigerian ethnomedicinal plants exhibited antioxidant activity》 was published in 2021. The authors were Ibrahim, Mutiat;Oyebanji, Elizabeth;Fowora, Muinah;Aiyeolemi, Ayobami;Orabuchi, Chiamaka;Akinnawo, Babajide;Adekunle, Adedotun A., and the article was included in《BMC Complementary Medicine and Therapies》. The author mentioned the following in the article:

Plants with an ethnobotanical history are known to harbor diverse group of endophytic fungi, which constitute major natural sources of bioactive compounds In the present study, we evaluated the antioxidant activity of endophytic fungi from eight Nigerian ethnomedicinal plants. Endophytic fungi were isolated from the leaves of Acalypha ornata, Albizia zygia, Alchornea cordifolia, Chrysophyllum albidum, Ficus exasperata, Gomphrena celosioides, Millettia thonningii, and Newbouldia laevis. Endophytic fungi were isolated from the leaves of selected plants via surface sterilization. Isolated fungi were identified by internal transcribed spacer (ITS-rDNA) sequence anal. Pure fungal strains were subjected to fermentation process on solid rice medium and metabolites extracted using ethyl-acetate. Fungal crude extracts were screened for antioxidant activity using 2, 2- diphenyl-1-picrylhydrazyl (DPPH) radical scavenging and reduction of ferric ion assays. Gas chromatog./mass spectrometry (GC/MS) anal. was used to identify the major chem. constituents in active fungal extracts A total of eighteen fungal endophytes with fungal codes CU (061 and 062); ZA (161, 162, 163, and 164); LO (261); CA (041, 042, and 043); FE (081, 082, and 084); GE (091); MO (211 and 212); and NA (021 and 022) were isolated from the eight ethnomedicinal plants A. ornata, A. zygia, A. cordifolia, C. albidum, F. exasperata, G. celosioides, M. thonningii, and N. laevis resp. ZA 163 and MO 211 fungal extracts showed significant (p < 0.05) radical scavenging activity with IC50 values of 50.53 ± 0.01 and 86.69 ± 0.02μg/mL resp. Fungal extract CA 041 demonstrated significantly (p < 0.01) higher iron chelating activity than standard gallic acid with absorbance values of 0.803 and 1.107 at 250 and 500μg/mL concentrations resp. Pyrogallol, phenol, 2,6-dimethoxy-, phytol, dl-alpha-tocopherol, alpha-tocospiro, oleamide, Me stearate, oleic acid, palmitic acid, campesterol, stigmasterol, β-sitosterol, urs-12-en-24-oic acid, 3-oxo-, Me ester, lup-20(29)-en-3-one, and lupeol were detected in the selected active extracts These results showed that leaves of the selected Nigerian plants harbor diverse group of endophytic fungi, which can be potential antioxidant resource. The experimental procedure involved many compounds, such as 2,2-Methylenebis(6-tert-butyl-p-cresol) (cas: 119-47-1) .

Application In Synthesis of 2,2-Methylenebis(6-tert-butyl-p-cresol)2,2′-Methylenebis(4-methyl-6-tert-butylphenol)(CAS: 119-47-1) is a natural product found in Streptomyces and Aspergillus fumigatus .

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Wang, Wanyi;Wang, Xin;Zhu, Qingqing;Zhou, Qunfang;Wang, Yawei;Liao, Chunyang;Jiang, Guibin published 《Occurrence of synthetic phenolic antioxidants in foodstuffs from ten provinces in China and its implications for human dietary exposure》. The research results were published in《Food and Chemical Toxicology》 in 2022.Application In Synthesis of 2,2-Methylenebis(6-tert-butyl-p-cresol) The article conveys some information:

Synthetic phenolic antioxidants (SPAs) are widely used as food additives to delay the oxidation rate of oils and oil products. The concentrations and compositions of SPAs in Chinese residents most popular daily foods and the resulting exposure risk of SPAs are not clear. Therefore, this study collected food samples in 13 food categories (n = 289) from 10 provinces in China. At least one of the SPAs was detected in approx. 99.7% of foodstuffs, and the concentration of ∑SPAs ranged from not detected to 7830 (geometric mean (GM): 296 ng/g wet weight). 2,6-2 tert Bu p-1,4-benzoquinone (BHT-Q) was the main transformation product, but SPAs in food tend to exist in the parent form. A significant difference between food categories was analyzed. The highest GM of ΣSPAs occurred in cereals and cereal products, which was approx. 8 times higher than that in beverages. The estimated daily intakes of ΣSPAs in Chinese preschoolers, school-age children, adults and elderly individuals were 22200, 9970, 7540 and 7700 ng/kg bw/day, resp. The exposure risks of SPAs decreased with age. This is the first simultaneous anal. of SPAs in multiple provinces and multiple categories of foodstuffs. To complete the study, the researchers used 2,2-Methylenebis(6-tert-butyl-p-cresol) (cas: 119-47-1) .

Application In Synthesis of 2,2-Methylenebis(6-tert-butyl-p-cresol)2,2′-Methylenebis(4-methyl-6-tert-butylphenol)(CAS: 119-47-1) is a natural product found in Streptomyces and Aspergillus fumigatus .

Reference:
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HPLC of Formula: 119-47-1《Metabolome-microbiome signatures in the fermented beverage, Kombucha》 was published in 2020. The authors were Villarreal-Soto, Silvia Alejandra;Bouajila, Jalloul;Pace, Mauro;Leech, John;Cotter, Paul D.;Souchard, Jean-Pierre;Taillandier, Patricia;Beaufort, Sandra, and the article was included in《International Journal of Food Microbiology》. The author mentioned the following in the article:

Kombucha is a fermented tea. Here we investigate the fermentation kinetics, metabolite production, microbiome and potential health promoting properties of three different kombucha consortia. Shotgun metagenomic sequencing revealed several dominant bacterial genera such as Komagataeibacter, Gluconacetobacter and Gluconobacter. Brettanomyces and Schizosaccharomyces were the most dominant yeasts identified. Species distribution reflected different patterns of sugar consumption, with S. pombe being present in samples with the highest sugar conversion. Liquid-liquid extractions were performed with organic solvents in order to obtain dried extracts, which were later characterized. HPLC-DAD and GC-MS anal. revealed differences in the production of organic acids, sugars, alcs. and phenolic compounds, where the presence of caffeine, propanoic acid and 2,3 butanediol differ greatly across the three kombuchas. Metabolomic anal. exhibited a link between the microbiota and the production of bioactive compounds in kombucha fermentation In vitro assays were carried out in order to evaluate potential health-promoting features of the fermented teas, with notable outcomes including antioxidant ability against DPPH radical and against the 15-lipoxygenase enzyme, indicating a potential anti-inflammatory activity. These investigations considerably enhance our understanding of the relationship between the microbiota and metabolites as well as health promoting potential of kombucha and have the potential for the development of future generations of kombucha products in which these relationships are optimized. The experimental procedure involved many compounds, such as 2,2-Methylenebis(6-tert-butyl-p-cresol) (cas: 119-47-1) .

HPLC of Formula: 119-47-12,2′-Methylenebis(4-methyl-6-tert-butylphenol)(CAS: 119-47-1) is a natural product found in Streptomyces and Aspergillus fumigatus .

Reference:
Alcohol – Wikipedia,
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