Malecki, Jan et al. published their research in International Journal of Environmental Research and Public Health in 2022 |CAS: 585-88-6

The Article related to protein bar athlete syrup physicochem nutritional microstructure sensory property, contact angle, industrial application, liquid fiber, nutritional value, optical microscopy, plant protein and other aspects.Application of 585-88-6

Malecki, Jan; Terpilowski, Konrad; Nastaj, Maciej; Solowiej, Bartosz G. published an article in 2022, the title of the article was Physicochemical, Nutritional, Microstructural, Surface and Sensory Properties of a Model High-Protein Bars Intended for Athletes Depending on the Type of Protein and Syrup Used.Application of 585-88-6 And the article contains the following content:

The main objective of this study was to investigate the possibility of using a combination of vegetable proteins from soybean (SOY), rice (RPC), and pea (PEA) with liquid syrups: tapioca fiber (TF), oligofructose (OF), and maltitol (ML) in the application of high-protein bars to determine the ability of these ingredients to modify the textural, physicochem., nutritional, surface properties, microstructure, sensory parameters, and technol. suitability. Ten variants of the samples were made, including the control sample made of whey protein concentrate (WPC) in combination with glucose syrup (GS). All combinations used had a pos. effect on the hardness reduction of the bars after the storage period. Microstructure and the contact angle showed a large influence on the proteins and syrups used on the features of the manufactured products, primarily on the increased hydrophobicity of the surface of samples made of RPC + ML, SOY + OF, and RPC + TF. The combination of proteins and syrups used significantly reduced the sugar content of the product. Water activity (<0.7), dynamic viscosity (<27 mPas•g/cm3), and sensory anal. (the highest final ratings) showed that bars made of RPC + OF, SOY + OF, and SOY + ML are characterized by a high potential for use in this type of products. The experimental process involved the reaction of SweetPearlR P300 DC Maltitol(cas: 585-88-6).Application of 585-88-6

The Article related to protein bar athlete syrup physicochem nutritional microstructure sensory property, contact angle, industrial application, liquid fiber, nutritional value, optical microscopy, plant protein and other aspects.Application of 585-88-6

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Dimitrokalli, Evangelia et al. published their research in Molecules in 2021 |CAS: 585-88-6

The Article related to warfarin sodium stability oral formulation, dsc, ir, raman spectroscopy, x-ray powder diffraction, crystallization, oral suspension, warfarin, warfarin clathrate, warfarin sodium amorphous and other aspects.Product Details of 585-88-6

Dimitrokalli, Evangelia; Fertaki, Stefani; Lykouras, Michail; Kokkinos, Petros; Orkoula, Malvina; Kontoyannis, Christos published an article in 2021, the title of the article was Warfarin Sodium Stability in Oral Formulations.Product Details of 585-88-6 And the article contains the following content:

Warfarin sodium is a low-dose pharmaceutical blood thinner that exists in two forms: the clathrate form and the amorphous form. In com. available warfarin sodium oral suspension, the active pharmaceutical ingredient (API) is added in the amorphous state. This study investigates the apparent instability of the com. available warfarin liquid oral formulation using Raman and IR spectroscopy, X-ray diffraction, differential scanning calorimetry, UV spectroscopy, and optical microscopy. Warfarin, not its sodium salt, was identified as the undissolved solid existing in the suspension. This was found to be due to the dissociation of sodium salt and the protonation of the warfarin ion in the liquid phase, which triggered the crystallization of the sparingly soluble unsalted form. The coexistence of protonated and unprotonated warfarin ions in the supernatant, as detected by Raman and UV spectroscopy, confirmed this assumption. Study of the dissolution of warfarin sodium amorphous salt and crystalline sodium clathrate in the placebo and pure water verified the results. The effect of pH and temperature on warfarin precipitation was also explored. The experimental process involved the reaction of SweetPearlR P300 DC Maltitol(cas: 585-88-6).Product Details of 585-88-6

The Article related to warfarin sodium stability oral formulation, dsc, ir, raman spectroscopy, x-ray powder diffraction, crystallization, oral suspension, warfarin, warfarin clathrate, warfarin sodium amorphous and other aspects.Product Details of 585-88-6

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Alcohol – Wikipedia,
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Gatidou, Georgia et al. published their research in Chemosphere in 2020 |CAS: 585-88-6

The Article related to food additive biodegradability artificial sweetener preservative coloring, micropollutants, oecd protocol, ready biodegradability, sweeteners, ultimate biodegradation kinetics, wastewater and other aspects.Synthetic Route of 585-88-6

On February 29, 2020, Gatidou, Georgia; Vazaiou, Niki; Thomaidis, Nikolaos S.; Stasinakis, Athanasios S. published an article.Synthetic Route of 585-88-6 The title of the article was Biodegradability assessment of food additives using OECD 301F respirometric test. And the article contained the following:

The ready biodegradability of twenty food additives, belonging to the classes of artificial sweeteners, natural sweeteners, preservatives and colorings, was investigated using activated sludge as inoculum and OECD 301F respirometric test. According to the results, saccharin, aspartame, sodium cyclamate, xylitol, erythritol, maltitol, potassium sorbate, benzoic acid and sodium ascorbate are characterized as readily biodegradable compounds, partial biodegradation (<60% during the test) was noticed for steviol, inulin, alitame, curcumin, ponceau 4R and tartrazine, while no biodegradation was observed for the other five compounds The duration of lag phase before the start of biodegradation varied between the target compounds, while their ultimate biodegradation half-life values ranged between 0.7 ± 0.1 days (benzoic acid) and 24.6 ± 1.0 days (curcumin). The expected removal of target compounds due to ultimate biodegradation mechanism was estimated for a biol. wastewater treatment system operated at a retention time of one day and percentages higher than 40% were calculated for sodium cyclamate, potassium sorbate and benzoic acid. Higher removal percentages are expected in full-scale Sewage Treatment Plants (STPs) due to the contribution of other mechanisms such as sorption to suspended solids, (bio)transformation and co-metabolic phenomena. Further biodegradation experiments should be conducted under different exptl. conditions for the food additives that did not fulfill the requirements of the applied protocol. Future studies should also focus on the occurrence and fate of food colorants and natural sweeteners in full-scale STPs. The experimental process involved the reaction of SweetPearlR P300 DC Maltitol(cas: 585-88-6).Synthetic Route of 585-88-6

The Article related to food additive biodegradability artificial sweetener preservative coloring, micropollutants, oecd protocol, ready biodegradability, sweeteners, ultimate biodegradation kinetics, wastewater and other aspects.Synthetic Route of 585-88-6

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Usai-Satta, Paolo et al. published their research in Nutrients in 2021 |CAS: 585-88-6

The Article related to hydrogen breath test nutrition management digestive disease, fodmap, fructose and sorbitol malabsorption, hydrogen breath testing, lactose malabsorption and intolerance, nutritional management and other aspects.Application of 585-88-6

Usai-Satta, Paolo; Oppia, Francesco; Lai, Mariantonia; Cabras, Francesco published an article in 2021, the title of the article was Hydrogen breath tests: are they really useful in the nutritional management of digestive disease?.Application of 585-88-6 And the article contains the following content:

Carbohydrate malabsorption is a frequent digestive problem associated with abdominal pain, bloating and diarrhea. Hydrogen breath testing (BT) represents the most reliable and validated diagnostic technique. The aim of this manuscript was to clarify the usefulness of BTs in the nutritional management of these disorders. A literature search for BT related to carbohydrate malabsorption was carried out using the online databases of Pubmed, Medline and Cochrane. Lactose BT showed good sensitivity and optimal specificity for lactose malabsorption. However, an accurate diagnosis of lactose intolerance should require blind lactose challenge although this method is difficult to utilize in clin. practice. Regarding dose-depending fructose and sorbitol malabsorption, BTs could not add diagnostic advantage compared with a direct dietary intervention. In addition, carbohydrates are fundamental components of fermentable oligo-, di- and monosaccharides and polyols (FODMAPs). Before starting a low FODMAP diet, lactose BT should be suggested in a population with low prevalence of hypolactasia. BTs represent a valid and noninvasive technique in many digestive conditions. Regarding the management of carbohydrate intolerance, lactose BT can be recommended with some limitations. No sufficient evidence is available about the usefulness of BTs for other sugars in clin. practice. The experimental process involved the reaction of SweetPearlR P300 DC Maltitol(cas: 585-88-6).Application of 585-88-6

The Article related to hydrogen breath test nutrition management digestive disease, fodmap, fructose and sorbitol malabsorption, hydrogen breath testing, lactose malabsorption and intolerance, nutritional management and other aspects.Application of 585-88-6

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Lin, Jieye et al. published their research in Acta Crystallographica, Section C: Structural Chemistry in 2021 |CAS: 585-88-6

The Article related to isopropyl deoxy ribohexopyranoside glucopyranoside crystal structure dft, dft, chemical synthesis, crystal structure, isopropyl 3-deoxy-α-d-glucopyranoside, isopropyl 3-deoxy-α-d-ribo-hexopyranoside and other aspects.Related Products of 585-88-6

On August 1, 2021, Lin, Jieye; Oliver, Allen G.; Meredith, Reagan J.; Carmichael, Ian; Serianni, Anthony S. published an article.Related Products of 585-88-6 The title of the article was Isopropyl 3-deoxy-α-D-ribo-hexopyranoside (isopropyl 3-deoxy-α-D-glucopyranoside): evaluating trends in structural parameters. And the article contained the following:

Iso-Pr 3-deoxy-α-D-ribo-hexopyranoside (iso-Pr 3-deoxy-α-D-glucopyranoside), C9H18O5, (I), crystallizes from a methanol-Et acetate solvent mixture at room temperature in a 4C1 chair conformation that is slightly distorted towards the C5SC1 twist-boat form. A comparison of the structural parameters in (I), Me α-D-glucopyranoside, (II), α-D-glucopyranosyl-(1→4)-D-glucitol (maltitol), (III), and 3-deoxy-α-D-ribo-hexopyranose (3-deoxy-α-D-glucopyranose), (IV), shows that most endocyclic and exocyclic bond lengths, valence bond angles and torsion angles in the aldohexopyranosyl rings are more affected by anomeric configuration, aglycon structure and/or the conformation of exocyclic substituents, such as hydroxymethyl groups, than by monodeoxygenation at C3. The structural effects observed in the crystal structures of (I)-(IV) were confirmed though d. functional theory (DFT) calculations in computed structures (I)c-(IV)c. Exocyclic hydroxymethyl groups adopt the gauche-gauche (gg) conformation (H5 anti to O6) in (I) and (III), and the gauche-trans (gt) conformation (C4 anti to O6) in (II) and (IV). The O-glycoside linkage conformations in (I) and (III) resemble those observed in disaccharides containing β-(1→4) linkages. The experimental process involved the reaction of SweetPearlR P300 DC Maltitol(cas: 585-88-6).Related Products of 585-88-6

The Article related to isopropyl deoxy ribohexopyranoside glucopyranoside crystal structure dft, dft, chemical synthesis, crystal structure, isopropyl 3-deoxy-α-d-glucopyranoside, isopropyl 3-deoxy-α-d-ribo-hexopyranoside and other aspects.Related Products of 585-88-6

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Ye, Xianfeng et al. published their research in Microbiome in 2020 |CAS: 585-88-6

The Article related to corallococcus predatory myxobacterium fusarium wilt cucumber soil microbial community, cooccurrence network, corallococcus sp. egb, fusarium oxysporum f. sp. cucumerinum, micropredator, myxobacteria, root exudates, soil microbiome and other aspects.Related Products of 585-88-6

On December 31, 2020, Ye, Xianfeng; Li, Zhoukun; Luo, Xue; Wang, Wenhui; Li, Yongkai; Li, Rui; Zhang, Bo; Qiao, Yan; Zhou, Jie; Fan, Jiaqin; Wang, Hui; Huang, Yan; Cao, Hui; Cui, Zhongli; Zhang, Ruifu published an article.Related Products of 585-88-6 The title of the article was A predatory myxobacterium controls cucumber Fusarium wilt by regulating the soil microbial community. And the article contained the following:

Myxobacteria are micropredators in the soil ecosystem with the capacity to move and feed cooperatively. Some myxobacterial strains have been used to control soil-borne fungal phytopathogens. However, interactions among myxobacteria, plant pathogens, and the soil microbiome are largely unexplored. In this study, we aimed to investigate the behaviors of the myxobacterium Corallococcus sp. strain EGB in the soil and its effect on the soil microbiome after inoculation for controlling cucumber Fusarium wilt caused by Fusarium oxysporum f. sp. cucumerinum (FOC). A greenhouse and a 2-yr field experiment demonstrated that the solid-state fermented strain EGB significantly reduced the cucumber Fusarium wilt by 79.6% (greenhouse), 66.0% (2015, field), and 53.9% (2016, field). Strain EGB adapted to the soil environment well and decreased the abundance of soil-borne FOC efficiently. Spatiotemporal anal. of the soil microbial community showed that strain EGB migrated towards the roots and root exudates of the cucumber plants via chemotaxis. Cooccurrence network anal. of the soil microbiome indicated a decreased modularity and community number but an increased connection number per node after the application of strain EGB. Several predatory bacteria, such as Lysobacter, Microvirga, and Cupriavidus, appearing as hubs or indicators, showed intensive connections with other bacteria. The predatory myxobacterium Corallococcus sp. strain EGB controlled cucumber Fusarium wilt by migrating to the plant root and regulating the soil microbial community. This strain has the potential to be developed as a novel biol. control agent of soil-borne Fusarium wilt. The experimental process involved the reaction of SweetPearlR P300 DC Maltitol(cas: 585-88-6).Related Products of 585-88-6

The Article related to corallococcus predatory myxobacterium fusarium wilt cucumber soil microbial community, cooccurrence network, corallococcus sp. egb, fusarium oxysporum f. sp. cucumerinum, micropredator, myxobacteria, root exudates, soil microbiome and other aspects.Related Products of 585-88-6

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Holm, Tobias Palle et al. published their research in European Journal of Pharmaceutics and Biopharmaceutics in 2021 |CAS: 585-88-6

The Article related to freeze dried protein formulation lyoprotectant stability, excipients, formulation development, freeze-drying, high throughput, image analysis, intrinsic fluorescence spectroscopy, protein stability, solid state analysis and other aspects.Product Details of 585-88-6

On March 31, 2021, Holm, Tobias Palle; Meng-Lund, Helena; Rantanen, Jukka; Jorgensen, Lene; Grohganz, Holger published an article.Product Details of 585-88-6 The title of the article was Screening of novel excipients for freeze-dried protein formulations. And the article contained the following:

The typical excipients used as bulking agents and lyoprotectants for freeze-drying are usually limited to only a few selected substances, such as sucrose and mannitol. Considering the sheer diversity amongst proteins, it is doubtful that this limited choice should, in every case, provide the best possible option in order to achieve the most stable product. In this work, a screening of 12 proteins with 64 excipients was conducted in order to increase the knowledge space of potential excipients. Three critical quality attributes (CQAs) of the freeze-dried products, namely the solid state, the cake appearance and the protein integrity based on changes in tryptophan fluorescence were investigated by high throughput X-ray powder diffraction, image anal. and intrinsic fluorescence spectroscopy, resp. It was found, that in some cases the excipient had a dominating influence on the CQAs, while in other cases the CQAs were primarily protein dependent, or that the CQAs were dependent on the combination of both. In the course of this investigation, a general view of potentially relevant excipients, and their interplay with various proteins, was obtained, thereby furthermore paving the way for the use of novel freeze-drying excipients. The experimental process involved the reaction of SweetPearlR P300 DC Maltitol(cas: 585-88-6).Product Details of 585-88-6

The Article related to freeze dried protein formulation lyoprotectant stability, excipients, formulation development, freeze-drying, high throughput, image analysis, intrinsic fluorescence spectroscopy, protein stability, solid state analysis and other aspects.Product Details of 585-88-6

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Ilhan, Zehra Esra et al. published their research in Neurobiology of Disease in 2022 |CAS: 585-88-6

The Article related to carbamazepine lamotrigine topiramate antiseizure agent gut bacteria epilepsy, anaerobic metabolism, antiepileptic drugs, drug formulations, epilepsy, intestinal epithelial cells, microbiome, parabens, pharmaco-resistance, seizures, toxicity and other aspects.Electric Literature of 585-88-6

On June 1, 2022, Ilhan, Zehra Esra; Brochard, Vincent; Lapaque, Nicolas; Auvin, Stephane; Lepage, Patricia published an article.Electric Literature of 585-88-6 The title of the article was Exposure to anti-seizure medications impact growth of gut bacterial species and subsequent host response. And the article contained the following:

Anti-seizure medications (ASMs) are the first line of treatment for seizure control in children with epilepsy. Cumulative evidence suggests an imbalanced gut microbiota in refractory epilepsy patients. We systematically investigated the differential antimicrobial impacts of nine ASM active ingredients, seven common excipients of ASMs, and four syrup formulations on core early-life gut microbiota strains. Addnl., we evaluated the toxicity and gene expression profiles of HT-29 colon epithelial cells when exposed to active ingredients with or without bacterial supernatants. The physicochem. structure of ASM active ingredients and bacterial phylogeny were found to be related to ASM toxicity. Carbamazepine, lamotrigine, and topiramate reduced the growth of more than ten strains along with syrup excipient propyl-paraben. Various artificial sweeteners present in ASM formulations stimulated the growth of gut bacterial strains. The active ingredients that were more toxic to bacterial strains also exhibited toxicity towards HT-29 cells, yet Bifidobacterium longum supernatant reduced cytotoxic effects of carbamazepine and lamotrigine. Akkermansia muciniphila or mixed community supernatants reduced the expression of drug resistance genes in HT-29 cell lines. In summary, our results indicate that several ASM active ingredients and their excipients regulate the growth of gut bacterial strains in a species-specific manner. Interactions between ASMs and gut epithelial cells might be modulated by gut microbial metabolites. The experimental process involved the reaction of SweetPearlR P300 DC Maltitol(cas: 585-88-6).Electric Literature of 585-88-6

The Article related to carbamazepine lamotrigine topiramate antiseizure agent gut bacteria epilepsy, anaerobic metabolism, antiepileptic drugs, drug formulations, epilepsy, intestinal epithelial cells, microbiome, parabens, pharmaco-resistance, seizures, toxicity and other aspects.Electric Literature of 585-88-6

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Alcohol – Wikipedia,
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Beltra, Marta et al. published their research in Nutrients in 2022 |CAS: 585-88-6

The Article related to food calorie sweetener nutritional characterization spain, added sugar, beverages, food products reformulation, health claims, intense sweeteners, no calorie sweeteners, non-nutritive sweeteners, nutrient composition, nutrition claims, polyols, regulation compliance and other aspects.HPLC of Formula: 585-88-6

Beltra, Marta; Tomas, Hector; Lopez, Juan C.; Borras, Fernando; Ropero, Ana B. published an article in 2022, the title of the article was Nutritional Description of Foods with Low- and No-Calorie Sweeteners in Spain: The BADALI Project.HPLC of Formula: 585-88-6 And the article contains the following content:

The use of low- and no-calorie sweeteners (LNCS) in foods has increased in recent years in response to the neg. effects of free sugar on health. However, the health impact of LNCS is still unclear. Studies of the prevalence of LNCS in foods have been published previously, including in Spain. However, the use of health (HCs) and nutrition claims (NCs) to promote these foods and a full nutritional characterization are largely lacking. For this purpose, we used the BADALI database with 4218 foods present in the Spanish market. Our results show that 9.3% of foods have LNCS (including both intense and polyols). Sucralose and acesulfame K were the intense sweeteners most frequently used (52.4% and 48.2%, resp.), whereas maltitol was the preferred polyol (20.3%). Of all foods with LNCS, 30% also had added sugar. Many more foods with LNCS presented HCs and NCs than those without. Sugar was the nutrient most frequently claimed in NCs for LNCS-containing foods, whereas vitamins were for those without these sweeteners. NCs compliance with regulation was similar in both conditions (60.1% for foods without and 63.9% for foods with LNCS). As expected, foods with LNCS had less total sugar content and energy. Surprisingly, the nutrient profile of yogurts with LNCS changed completely: less total and saturated fat, whereas more proteins and sodium. Biscuits with LNCS contained more fiber. The results of our study reveal that the prevalence of LNCS is becoming high in some food types in Spain and that foods containing LNCS are more frequently promoted with HCs/NCs. In addition, it confirms the general reduction in energy and sugar content expected in foods with LNCS. Furthermore, it suggests a reformulation of products beyond sugar content. The experimental process involved the reaction of SweetPearlR P300 DC Maltitol(cas: 585-88-6).HPLC of Formula: 585-88-6

The Article related to food calorie sweetener nutritional characterization spain, added sugar, beverages, food products reformulation, health claims, intense sweeteners, no calorie sweeteners, non-nutritive sweeteners, nutrient composition, nutrition claims, polyols, regulation compliance and other aspects.HPLC of Formula: 585-88-6

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Alcohol – Wikipedia,
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Yang, Hua et al. published their research in Journal of Agricultural and Food Chemistry in 2022 |CAS: 585-88-6

The Article related to pyrroloquinoline quinone dependent dehydrogenase depa devosia structure deoxynivalenol detoxification, devosia pqq dependent dehydrogenase depa structure deoxynivalenol detoxification, crystal structure, deoxynivalenol, enzyme engineering, quinone-dependent dehydrogenase, substrate specificity and other aspects.Computed Properties of 585-88-6

On June 8, 2022, Yang, Hua; Yan, Ruxue; Li, Yue; Lu, Zhaoxin; Bie, Xiaomei; Zhao, Haizhen; Lu, Fengxia; Chen, Meirong published an article.Computed Properties of 585-88-6 The title of the article was Structure-function analysis of a quinone-dependent dehydrogenase capable of deoxynivalenol detoxification. And the article contained the following:

The pyrroloquinoline quinone (PQQ)-dependent dehydrogenase DepA detoxifies deoxynivalenol (DON) by converting the C3-OH into a keto group. Herein, two crystal structures of DepA and its complex with PQQ were determined, together with biochem. evidence confirming the interactions of DepA with PQQ and DON and revealing a unique tyrosine residue important for substrate selection. Furthermore, four loops over the active site essential for DepA activity were identified, of which three loops were stabilized by PQQ, and the fourth loop invisible in both structures was considered important for binding DON, together constituting a lid for the active site. Preliminary engineering of the loop showed its potential for enzyme improvement. This study provides structural insights into how a PQQ-dependent dehydrogenase is equipped with the function of DON conversion and for the first time shows the necessity of a lid structure for PQQ-dependent dehydrogenase activity, laying foundation for structure-based design to enhance catalysis efficiency. The experimental process involved the reaction of SweetPearlR P300 DC Maltitol(cas: 585-88-6).Computed Properties of 585-88-6

The Article related to pyrroloquinoline quinone dependent dehydrogenase depa devosia structure deoxynivalenol detoxification, devosia pqq dependent dehydrogenase depa structure deoxynivalenol detoxification, crystal structure, deoxynivalenol, enzyme engineering, quinone-dependent dehydrogenase, substrate specificity and other aspects.Computed Properties of 585-88-6

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