Tag: 300-400

Ospemifene for the treatment of vulvar and vaginal atrophy: A meta-analysis of randomized trials. Part I: Evaluation of efficacy was written by Di Donato, Violante;schiavi, Michele Carlo;iacobelli, Valentina;D’oria, Ottavia;Kontopantelis, Evangelos;Simoncini, Tommaso;Muzii, Ludovico;Benedetti Panici, Pierluigi. And the article was included in Maturitas in 2019.Recommanded Product: 128607-22-7 This article mentions the following:

Objective: To evaluate the efficacy of ospemifene in treating dyspareunia associated with postmenopausal vulvo-vaginal atrophy (VVA). Methods: A structured search was carried out in PubMed-Medlin, Embase, Cochrane Controlled Trials Register databases through to 31 July 2018. The search included the following terms: “Ospemifene”, “vulvovaginal atrophy”, “dyspareunia”, “SERM” and “randomized controlled trial” (RCTs). Four outcomes were selected: vaginal pH; proportions of parabasal and superficial vaginal cells; and perception of the most bothersome symptom (vaginal dryness or dyspareunia). A random-effects model was used in the meta-anal. Study quality and bias risk were assessed with the Cochrane tool. Results: Six RCTs comparing the efficacy of ospemifene against placebo after 12 and 52 wk of treatment were included in the meta-anal. At 12 wk, changes in vaginal Ph (SMD: -0.96, 95% CI:-1.12 to -0.81; p < 0.0001), parabasal cells (SMD: -36.84 95% CI -46.95 to -26.72; p < 0.0001), superficial cells (SMD: 8.23, 95% CI 3.73-12.74, p < 0.0003), and dyspareunia (SMD= – 2.70, 95% CI – 2.88 to -2.52, p < 0.0001) indicated that ospemifene was more effective than placebo. Conclusion: The present meta-anal. suggests that ospemifene 60 mg is associated with significant improvement in the morphol. and physiol. features of the vaginal mucosa that correlate with the symptoms associated with postmenopausal VVA. In the experiment, the researchers used many compounds, for example, (Z)-2-(4-(4-Chloro-1,2-diphenylbut-1-en-1-yl)phenoxy)ethan-1-ol (cas: 128607-22-7Recommanded Product: 128607-22-7).

(Z)-2-(4-(4-Chloro-1,2-diphenylbut-1-en-1-yl)phenoxy)ethan-1-ol (cas: 128607-22-7) belongs to alcohols. The oxygen atom of the strongly polarized O―H bond of an alcohol pulls electron density away from the hydrogen atom. This polarized hydrogen, which bears a partial positive charge, can form a hydrogen bond with a pair of nonbonding electrons on another oxygen atom. The most common reactions of alcohols can be classified as oxidation, dehydration, substitution, esterification, and reactions of alkoxides.Recommanded Product: 128607-22-7

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Comparative study on lignocellulose liquefaction in water, ethanol, and water/ethanol mixture: Roles of ethanol and water was written by Feng, Shanghuan;Wei, Rufei;Leitch, Mathew;Xu, Chunbao Charles. And the article was included in Energy (Oxford, United Kingdom) in 2018.Recommanded Product: 109-17-1 This article mentions the following:

This study aimed to investigate the roles of ethanol and water in the water/ethanol mixed solvent in liquefaction of lignocellulose biomass. To this end, an organosolv lignin, cellulose, cellulose/lignin (50:50, weight/weight) mixture and an acetone extracted white birch bark (EWBB) were comparatively liquefied in pure water, water/ethanol mixture (50:50, volume/volume) and pure ethanol at fixed condition (300 °C and 15 min). It was demonstrated that biomass liquefaction efficiency in three reaction media with respect to the bi-crude yield followed the order of water/ethanol mixed solvent >> pure water > pure ethanol regardless of the feedstocks. Cellulose derived bio-crudes mainly contained esters, furfurals and furfurals derivatives, and carboxylic acid substantially existed in the bio-crude from cellulose liquefaction in water, while lignin derived bio-crude mainly contained aromatics, as expected. It was found that hot-compress water accelerated biomass depolymerization by hydrolyzing cellulose/hemi-cellulose, while on the other hand ethanol promoted lignin degradation by dissolving the de-polymerized lignin products and hence prevented the repolymn. of the reaction intermediates. In addition, the mixed ethanol-water solvent increased the permeation of the solvent into the lignocellulose biomass structure, and increased the solubility of liquefaction intermediates, hence contributing to a higher bio-crude yield in liquefaction of lignocellulose biomass. In the experiment, the researchers used many compounds, for example, ((Oxybis(ethane-2,1-diyl))bis(oxy))bis(ethane-2,1-diyl) bis(2-methylacrylate) (cas: 109-17-1Recommanded Product: 109-17-1).

((Oxybis(ethane-2,1-diyl))bis(oxy))bis(ethane-2,1-diyl) bis(2-methylacrylate) (cas: 109-17-1) belongs to alcohols. A strong base can deprotonate an alcohol to yield an alkoxide ion (R―O−). For example, sodamide (NaNH2), a very strong base, abstracts the hydrogen atom of an alcohol. Tertiary alcohols cannot be oxidized at all without breaking carbon-carbon bonds, whereas primary alcohols can be oxidized to aldehydes or further oxidized to carboxylic acids.Recommanded Product: 109-17-1

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Hybrid polymeric systems of mesoporous silica/hydroxyapatite nanoparticles applied as antitumor drug delivery platform was written by dos Apostolos, Rafaela C. R.;Andrade, Gracielle F.;da Silva, Wellington M.;de Assis Gomes, Dawidson;de Miranda, Marcelo C.;de Sousa, Edesia M. B.. And the article was included in International Journal of Applied Ceramic Technology in 2019.Recommanded Product: 109-17-1 This article mentions the following:

In this study, we report the production of a mesoporous silica/hydroxyapatite-based nanocomposite containing copper (Cu) functionalized with methacrylic acid (MAA), a pH-sensitive polymer. The functionalization of the nanoparticles surface was performed using the microwave method in order to anchor the crosslinking tetraethylene glycol dimethacrylate (TEGDMA), onto the nanoparticles surface followed by MAA polymerization The materials were characterized by XRD, XRF spectroscopy, scanning and transmission electron microscopy, Fourier transform IR spectroscopy, thermal anal., zeta potential, and elemental anal. Studies of the incorporation and release of the antitumor methotrexate drug were performed in order to evaluate the potential use of these drug carrier systems in cancer therapy. Moreover, the in vitro cytotoxicity of the samples in fibroblast and SAOS-2 cells was investigated, and the activity of the adipose-derived stem cell alk. phosphatase on nanocomposites was studied by in vitro assays. The results indicate that the Cu-containing nanocomposites can be easily produced and that these compositions have beneficial effects in stem cells, maintaining cell viability, and allowing alk. phosphatase expression. In conclusion, data from this work show that the nanocomposites obtained have adequate characteristic to be used as drug delivery platform. Furthermore, the biomaterial is a promising structure for treatment of bone tumor. In the experiment, the researchers used many compounds, for example, ((Oxybis(ethane-2,1-diyl))bis(oxy))bis(ethane-2,1-diyl) bis(2-methylacrylate) (cas: 109-17-1Recommanded Product: 109-17-1).

((Oxybis(ethane-2,1-diyl))bis(oxy))bis(ethane-2,1-diyl) bis(2-methylacrylate) (cas: 109-17-1) belongs to alcohols. Alcohols are among the most common organic compounds. They are used as sweeteners and in making perfumes, are valuable intermediates in the synthesis of other compounds, and are among the most abundantly produced organic chemicals in industry. Grignard and organolithium reagents are powerful tools for organic synthesis, and the most common products of their reactions are alcohols.Recommanded Product: 109-17-1

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Polymer microparticles with a cavity designed for transarterial chemo-embolization with crystalline drug formulations was written by Karina, Aigerim;Benzina, Abderazak;Tazhibayeva, Samal;Fan, Haiyan;Koole, Levinus H.. And the article was included in Journal of Biomedical Materials Research, Part B: Applied Biomaterials in 2021.Reference of 109-17-1 This article mentions the following:

Transarterial chemo-embolization with drug-eluting embolic beads (DEB-TACE) is still evolving. Recent developments include the introduction of radiopaque (X-ray imageable) drug-eluting particles. Here, we report on conceptually different radiopaque polymeric drug-eluting embolic particles, which are (i), cross-linked poly(methacrylates); (ii), radiopaque; (iii), microporous. Furthermore, the particles are not perfectly spherical: they have a large indentation in the sense that they are either a spherical/cup-shaped or ellipsoid/mouth-shaped. The micropores and the large indentation can confer useful features upon the particles, since they can be filled with a crystalline lipophilic chemotherapeutic drug. It is important, in this respect that (i), many potent chemotherapeutics are lipophilic and crystalline; (ii), available drug-eluting beads (DEBs) have the limitation that they can only be used in combination with water-soluble chemotherapeutic agents. Cup- and mouth-shaped particles were obtained in a Cu(0) catalyzed free-radical polymerization reaction. The microparticles could be charged with crystalline drug, in such a manner that the crystals reside in both the micropores and the large cavity, and in quantities that would be required for effective local chemotherapy. The antifungal drug voriconazole, lipophilic, and crystalline, was used to demonstrate this. We believe that the ability of the microporous/cavitated DEBs to carry lipophilic chemotherapeutic drugs is especially important. DEB-TACE is likely to become a cornerstone method of interventional oncol. in the years ahead, and the new embolic particles described herein hold the promise of becoming scope widening for the technique. In the experiment, the researchers used many compounds, for example, ((Oxybis(ethane-2,1-diyl))bis(oxy))bis(ethane-2,1-diyl) bis(2-methylacrylate) (cas: 109-17-1Reference of 109-17-1).

((Oxybis(ethane-2,1-diyl))bis(oxy))bis(ethane-2,1-diyl) bis(2-methylacrylate) (cas: 109-17-1) belongs to alcohols. Under appropriate conditions, inorganic acids also react with alcohols to form esters. To form these esters, a wide variety of specialized reagents and conditions can be used. Converting an alcohol to an alkene requires removal of the hydroxyl group and a hydrogen atom on the neighbouring carbon atom. Dehydrations are most commonly carried out by warming the alcohol in the presence of a strong dehydrating acid, such as concentrated sulfuric acid.Reference of 109-17-1

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Knowledge of genito-urinary syndrome of menopause among Italian gynecologists: the DIADEM survey was written by Alvisi, Stefania;Baldassarre, Maurizio;Gava, Giulia;Mancini, Ilaria;Cagnacci, Angelo;Seracchioli, Renato;Meriggiola, Maria Cristina. And the article was included in Maturitas in 2021.Application of 128607-22-7 This article mentions the following:

The objective of this study was to present an updated picture of the knowledge and attitudes of Italian gynecologists with regard to the genitourinary syndrome of menopause (GSM). An anonymous survey was sent via electronic mail to 3892 gynecologists. Three hundred and seventy-four out of 3892 invited Italian gynecologists replied to the survey (response rate 9.7%). Most (84%) had a good knowledge of GSM and 74% reported that they investigated it during clinic visits, but most of them underestimated its prevalence. The most frequently prescribed treatment was topical hormonal therapy (60%), followed by vaginal moisturizers and lubricants (16%), ospemifene (12%) and systemic hormone therapy (12%). According to the clin. experience of respondents, the most effective therapy is local hormonal therapy (36%), followed by ospemifene (30%). According to respondents, less than 50% of patients continue therapy after 12 mo, due to the discomfort in vaginal application, the cost of oral therapies and the fear of possible side-effects. With the limitation of the low response rate, this study suggests that although Italian gynecologists who answered the survey had some knowledge of GSM, they underestimated its prevalence, did not know its most bothersome symptoms and had inadequate knowledge of the efficacy of treatments, patient compliance and satisfaction. In the experiment, the researchers used many compounds, for example, (Z)-2-(4-(4-Chloro-1,2-diphenylbut-1-en-1-yl)phenoxy)ethan-1-ol (cas: 128607-22-7Application of 128607-22-7).

(Z)-2-(4-(4-Chloro-1,2-diphenylbut-1-en-1-yl)phenoxy)ethan-1-ol (cas: 128607-22-7) belongs to alcohols. A strong base can deprotonate an alcohol to yield an alkoxide ion (R―O−). For example, sodamide (NaNH2), a very strong base, abstracts the hydrogen atom of an alcohol. The most common reactions of alcohols can be classified as oxidation, dehydration, substitution, esterification, and reactions of alkoxides.Application of 128607-22-7

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Finely Formed, Kinetically Modulated Wrinkle Structures in UV-Crosslinkable Liquid Prepolymers was written by Park, Seung Koo;Kwark, Young-Je;Moon, Jaehyun;Joo, Chul Woong;Yu, Byounggon;Lee, Jeong-Ik. And the article was included in Macromolecular Rapid Communications in 2015.Synthetic Route of C16H26O7 This article mentions the following:

Special characteristics of wrinkles such as a scattering source and a high surface area are finding use in high-tech applications. UV-crosslinkable prepolymers are occasionally used for fabricating wrinkled films. Wavelength of the wrinkles formed from the prepolymers is several tens and hundreds of micrometers. Here, a UV-crosslinkable liquid prepolymer was synthesized to spontaneously form wrinkle structures in the order of several micrometers. Double layers with a very thin hard skin and a soft and contractible foundation were formed at the same time, by ensuring that all the absorbance wavelengths of the photoinitiator were shorter than the min. wavelength at which the prepolymer is transparent. The rate of photo-crosslinking reaction, R_p, is also found to affect the thickness of the skin and foundation layers at the early UV-curing stage. The first-order apparent rate constant, k_app, is between ≈0.20 and ≈0.69 s^-1 for the wrinkle formation. This wrinkle structures can be simply modulated by changing R_p. In the experiment, the researchers used many compounds, for example, ((Oxybis(ethane-2,1-diyl))bis(oxy))bis(ethane-2,1-diyl) bis(2-methylacrylate) (cas: 109-17-1Synthetic Route of C16H26O7).

((Oxybis(ethane-2,1-diyl))bis(oxy))bis(ethane-2,1-diyl) bis(2-methylacrylate) (cas: 109-17-1) belongs to alcohols. Similar to water, an alcohol can be pictured as having an sp3 hybridized tetrahedral oxygen atom with nonbonding pairs of electrons occupying two of the four sp3 hybrid orbitals. A multistep synthesis may use Grignard-like reactions to form an alcohol with the desired carbon structure, followed by reactions to convert the hydroxyl group of the alcohol to the desired functionality.Synthetic Route of C16H26O7

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Molecular imprinted hydrogels in drug delivery applications was written by Bates, Jeffrey S.;Whitson, Luke R.;Albertson, Kelan M.;Hickerson, Nathan S.;Nichols, Patrick E.;Larson, Bethany E.;Sparks, Taylor D.. And the article was included in MRS Online Proceedings Library in 2015.Formula: C16H26O7 This article mentions the following:

Mol. imprinting is the process by which mols. are imprinted into the matrix of a material through non-covalent bonding, including hydrogen bonding and van der Waals interactions. In this study hydrogels were imprinted with glaucoma medication with the purpose of creating a reusable ocular drug delivery device with reversible binding sites. The material was synthesized and tested with UV-Vis spectroscopy to determine the concentration of the released drug after twelve hours in distilled water. Modifications were made to the polymer to explore methods required for the proper delivery of the drug over an adequate period of time. In the experiment, the researchers used many compounds, for example, ((Oxybis(ethane-2,1-diyl))bis(oxy))bis(ethane-2,1-diyl) bis(2-methylacrylate) (cas: 109-17-1Formula: C16H26O7).

((Oxybis(ethane-2,1-diyl))bis(oxy))bis(ethane-2,1-diyl) bis(2-methylacrylate) (cas: 109-17-1) belongs to alcohols. Alcohols are among the most common organic compounds. They are used as sweeteners and in making perfumes, are valuable intermediates in the synthesis of other compounds, and are among the most abundantly produced organic chemicals in industry. A multistep synthesis may use Grignard-like reactions to form an alcohol with the desired carbon structure, followed by reactions to convert the hydroxyl group of the alcohol to the desired functionality.Formula: C16H26O7

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Ospemifene for the treatment of vulvar and vaginal atrophy: A meta-analysis of randomized trials. Part II: Evaluation of tolerability and safety was written by Di Donato, Violante;Schiavi, Michele Carlo;Iacobelli, Valentina;D’oria, Ottavia;Kontopantelis, Evangelos;Simoncini, Tommaso;Muzii, Ludovico;Benedetti Panici, Pierluigi. And the article was included in Maturitas in 2019.Synthetic Route of C24H23ClO2 This article mentions the following:

Objective: To evaluate the tolerability and safety of ospemifene in treating dyspareunia associated with postmenopausal vulvo- vaginal atrophy (VVA). Methods: The literature was searched through to 31 July 2018 to identify randomized controlled trials comparing ospemifene 60 mg against placebo for the treatment of VVA. Two groups of outcomes were selected: 1. side-effects, including hot flushes, urinary tract infection (UTI), headache, deep venous thrombosis (DVT), coronary heart disease (CHD), cardiovascular event (CVE), discontinuation due to side-effects, serious adverse event (SAE); 2. Safety, in relation to endometrial thickness, vaginal bleeding, breast tenderness, breast and endometrial cancer. A random-effects model was used in the meta-anal. Study quality and bias risk were assessed with the Cochrane tool. Results: In the group of patients treated with ospemifene, there was a slightly higher rate of hot flushes (OR:2.36, 95% CI 1.26-4.42; p = 0.007) and UTI (OR:1.97, 95% CI 1.23-3.14, p = 0.005) at 12 wk of treatment, but no differences were noted after 52 wk. The incidence of headaches, DVT, CHD, CVE, discontinuation of treatment, and SAEs was not significantly different between groups. Ospemifene treatment was statistically associated with a greater endometrial thickness in women with an intact uterus both at 12 wk SMD: 0.40, (95% CI 0.17 to 0.63, p < 0.0005) and at 52 wk (SMD: 0.62, 95% CI 0.23-1.01, p = 0.002); however, this increase was not clin. relevant. The incidence of vaginal bleeding, endometrial cancer, breast tenderness, breast and endometrial cancer was not significantly different between groups. Conclusions: This meta-anal. suggests that ospemifene treatment is well tolerated and presents a good safety profile. Long-term safety studies with larger samples, which include patients at high risk, are warranted. In the experiment, the researchers used many compounds, for example, (Z)-2-(4-(4-Chloro-1,2-diphenylbut-1-en-1-yl)phenoxy)ethan-1-ol (cas: 128607-22-7Synthetic Route of C24H23ClO2).

(Z)-2-(4-(4-Chloro-1,2-diphenylbut-1-en-1-yl)phenoxy)ethan-1-ol (cas: 128607-22-7) belongs to alcohols. Alkyl halides are often synthesized from alcohols, in effect substituting a halogen atom for the hydroxyl group. Tertiary alcohols cannot be oxidized at all without breaking carbon-carbon bonds, whereas primary alcohols can be oxidized to aldehydes or further oxidized to carboxylic acids.Synthetic Route of C24H23ClO2

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Ultrafast and Stable CO₂ Capture Using Alkali Metal Salt-Promoted MgO-CaCO₃ Sorbents was written by Cui, Hongjie;Zhang, Qiming;Hu, Yuanwu;Peng, Chong;Fang, Xiangchen;Cheng, Zhenmin;Galvita, Vladimir V.;Zhou, Zhiming. And the article was included in ACS Applied Materials & Interfaces in 2018.Electric Literature of C6H20CaO11 This article mentions the following:

As a potential candidate for precombustion CO₂ capture at intermediate temperatures (200-400 °C), MgO-based sorbents usually suffer from low kinetics and poor cyclic stability. Herein, a general and facile approach is proposed for the fabrication of high-performance MgO-based sorbents via incorporation of CaCO₃ into MgO followed by deposition of a mixed alkali metal salt (AMS). The AMS-promoted MgO-CaCO₃ sorbents are capable of adsorbing CO₂ at an ultrafast rate, high capacity, and good stability. The CO₂ uptake of sorbent can reach as high as above 0.5 g_CO2 g_sorbent^-1 after only 5 min of sorption at 350 °C, accounting for vast majority of the total uptake. In addition, the sorbents are very stable even under severe but more realistic conditions (desorption in CO₂ at 500 °C), where the CO₂ uptake of the best sorbent is stabilized at 0.58 g_CO2 g_sorbent^-1 in 20 consecutive cycles. The excellent CO₂ capture performance of the sorbent is mainly due to the promoting effect of molten AMS, the rapid formation of CaMg(CO₃)₂, and the plate-like structure of sorbent. The exceptional ultrafast rate and the good stability of the AMS-promoted MgO-CaCO₃ sorbents promise high potential for practical applications, such as precombustion CO₂ capture from integrated gasification combined cycle plants and sorption-enhanced water gas shift process. In the experiment, the researchers used many compounds, for example, Calcium 2-hydroxypropanoate pentahydrate (cas: 5743-47-5Electric Literature of C6H20CaO11).

Calcium 2-hydroxypropanoate pentahydrate (cas: 5743-47-5) belongs to alcohols. Under appropriate conditions, inorganic acids also react with alcohols to form esters. To form these esters, a wide variety of specialized reagents and conditions can be used. Tertiary alcohols cannot be oxidized at all without breaking carbon-carbon bonds, whereas primary alcohols can be oxidized to aldehydes or further oxidized to carboxylic acids.Electric Literature of C6H20CaO11

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Incidence of venous thromboembolism among postmenopausal women prescribed ospemifene, selective estrogen receptor modulators for noncancer indications, or untreated vulvar and vaginal atrophy. was written by Nordstrom, Beth L;Cai, Bin;De Gregorio, Fabio;Dhalwani, Nafeesa;Fraeman, Kathy H;Yoshida, Yuki;Gibbs, Trevor. And the article was included in Menopause (New York, N.Y.) in 2020.SDS of cas: 128607-22-7 This article mentions the following:

OBJECTIVE: Ospemifene is a nonsteroidal selective estrogen receptor modulator (SERM) for the treatment of moderate symptomatic vulvar and vaginal atrophy (VVA) due to menopause. A postauthorization safety study is currently examining the incidence of venous thromboembolism (VTE) among postmenopausal women receiving ospemifene or other SERM (raloxifene, bazedoxifene, or tamoxifen, for noncancer indications), or with untreated VVA. METHODS: This interim analysis used the US MarketScan Commercial and Medicare Supplemental claims database from 2013 to 2017 to identify incident VTE. The incidence rate and 95% confidence interval of VTE during the first continuous course of treatment (or continuous untreated time for the untreated cohort) were calculated for each cohort overall and by age group, with sensitivity analyses examining incidence in the short term (up to 90 days) and long term (all available follow-up, regardless of treatment changes). RESULTS: Analyses included 8,188 ospemifene users, 11,777 other SERM users, and 220,242 women with untreated VVA. The incidence per 1,000 person-years and 95% confidence interval of VTE were 3.7 (1.7-7.1) for ospemifene, 11.5 (8.9-14.6) for other SERM, and 11.3 (10.8-11.7) for untreated VVA. Stratification by age and altering the time frame for analysis produced results with similar patterns to the primary analysis. CONCLUSIONS: This interim analysis of an ongoing study suggests a favorable safety profile for ospemifene with respect to VTE. Comparative analyses with covariate adjustment will be performed when data accrual is complete. In the experiment, the researchers used many compounds, for example, (Z)-2-(4-(4-Chloro-1,2-diphenylbut-1-en-1-yl)phenoxy)ethan-1-ol (cas: 128607-22-7SDS of cas: 128607-22-7).

(Z)-2-(4-(4-Chloro-1,2-diphenylbut-1-en-1-yl)phenoxy)ethan-1-ol (cas: 128607-22-7) belongs to alcohols. Similar to water, an alcohol can be pictured as having an sp3 hybridized tetrahedral oxygen atom with nonbonding pairs of electrons occupying two of the four sp3 hybrid orbitals. The most common reactions of alcohols can be classified as oxidation, dehydration, substitution, esterification, and reactions of alkoxides.SDS of cas: 128607-22-7

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts