Tag: 200-300

Safety of rel-(1R,2S)-1,2-Diphenylethane-1,2-diol《Enantioselective acyl transfer catalysis by a combination of common catalytic motifs and electrostatic interactions》 was published in 2016. The authors were Mandai, Hiroki;Fujii, Kazuki;Yasuhara, Hiroshi;Abe, Kenko;Mitsudo, Koichi;Korenaga, Toshinobu;Suga, Seiji, and the article was included in《Nature Communications》. The author mentioned the following in the article:

It was demonstrated that by attaching a binaphthyl moiety, appropriately modified to establish H-bonding interactions within the key intermediates in the catalytic cycle and a 4-aminopyridyl unit, exceptionally efficient organic mols. could be prepared that facilitated enantioselective acyl transfer reactions. As little as 0.5 mol% of a member of the new catalyst class was sufficient to generate acyl-substituted all-carbon quaternary stereogenic centers in quant. yield and in up to 98:2 enantiomeric ratio (er) in 5 h. Kinetic resolution or desymmetrization of 1,2-diol could be performed with high efficiency and enantioselectivity as well.rel-(1R,2S)-1,2-Diphenylethane-1,2-diol (cas: 579-43-1) were involved in the experimental procedure.

Desymmetrization of rel-(1R,2S)-1,2-Diphenylethane-1,2-diol(cas:579-43-1 Safety of rel-(1R,2S)-1,2-Diphenylethane-1,2-diol) using chiral phosphine catalyst has been reported. Conversion of meso-hydrobenzoin to trans-stillbene oxide by treatment with an aryl sulfonyl chloride and aqueous sodium hydroxide has been reported.

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Kodama, Susumu;Yoshii, Nao;Ota, Akihiro;Takeshita, Jun-ichi;Yoshinari, Kouichi;Ono, Atsushi published 《Association between in vitro nuclear receptor-activating profiles of chemical compounds and their in vivo hepatotoxicity in rats》 in 2021. The article was appeared in 《Journal of Toxicological Sciences》. They have made some progress in their research.Product Details of 599-64-4 The article mentions the following:

The liver plays critical roles to maintain homeostasis of living organisms and is also a major target organ of chem. toxicity. Meanwhile, nuclear receptors (NRs) are known to regulate major liver functions and also as a critical target for hepatotoxic compounds In this study, we established mammalian one-hybrid assay systems for five rat-derived NRs, namely PXR, PPARα, LXRα, FXR and RXRα, and evaluated a total of 326 compounds for their NR-activating profiles. Then, we assessed the association between their NR-activating profile and hepatotoxic endpoints in repeated-dose toxicity data of male rats from Hazard Evaluation Support System. In the in vitro cell-based assays, 68, 38, 20, 17 and 17 compounds were identified as positives for PXR, PPARα, LXRα, FXR and RXRα, resp. The association analyses demonstrated that the PXR-pos. compounds showed high frequency of endpoints related to liver hypertrophy, such as centrilobular hepatocellular hypertrophy, suggesting that PXR activation is involved in chem.-induced liver hypertrophy in rats. It is intriguing to note that the PXR-pos. compounds also showed statistically significant associations with both prolonged activated partial thromboplastin time and prolonged prothrombin time, suggesting a possible involvement of PXR in the regulation of blood clotting factors. Collectively, our approach may be useful for discovering new functions of NRs as well as understanding the complex mechanism for hepatotoxicity caused by chem. compounds4-(2-Phenylpropan-2-yl)phenol (cas: 599-64-4) were involved in the experimental procedure.

4-(2-Phenylpropan-2-yl)phenol(cas:599-64-4) is a natural product found in Panax ginseng.Product Details of 599-64-4 4-(2-Phenylpropan-2-yl)phenol is a useful reagent for preparing and characterizing aromatic polyphosphonates as high refractive index polymers.

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Sonnette, Alexandre;Delhomme, Olivier;Alleman, Laurent Y.;Coddeville, Patrice;Millet, Maurice published 《A versatile method for the quantification of 100 SVOCs from various families: Application to indoor air, dust and bioaccessibility evaluation》 in 2021. The article was appeared in 《Microchemical Journal》. They have made some progress in their research.Name: 4-tert-Octylphenol The article mentions the following:

A method coupling automated thermal desorption (ATD) with in-tube derivatization and solid phase micro-extraction (SPME), with on-injector derivatization gas chromatog. – tandem mass spectrometry (GC/MSMS) was developed and used for the simultaneous quantification of 100 semivolatile (SVOCs) pollutants (50 pesticides, 16 PAHs, 22 PCBs, 7 phthalates and 5 alkylphenols) in indoor air, indoor dust, and for bioaccessibility evaluation. Chem. compounds in indoor air were sampled on Tenax-TA passive samplers (PAS) exposed for 15 days, while dust was collected on silicon carbide (SiC) foam using a custom made vacuum cleaner head. After sampling, Tenax tubes from PAS were introduced directly into a thermal desorption tube while dust was extracted using accelerated solvent extractor (ASE). Extract is then used to spike clean Tenax-TA tube that is then treated as a Tenax from PAS. The derivatization agent (MtBSTFA) and a mix of internal standards were added into the tubes before thermal desorption and anal. by GC/MSMS. The SPME technique was applied to extract the 100 SVOCs from the different tested bioaccessibility solutions (saliva, gastric, intestinal). This method permits the determination of 100 pollutants in a single run, including those requiring a derivatization step, with very low quantification and detection limits. Indeed, ATD-GC/MSMS technic presents very low LOD (0.002 to 0.17 ng) and LOQ (0.007 to 0.56 ng) values while SPME-GC/MSMS displays slightly higher LOD (0.044 to 12.3 ng) and LOQ (0.10 to 37.0 ng) ranges. The experimental procedure involved many compounds, such as 4-tert-Octylphenol (cas: 140-66-9) .

4-tert-Octylphenol(cas: 140-66-9) is a common environmental pollutant showing weak estrogenic effects.Name: 4-tert-Octylphenol It has been shown to cause harm to vertebrate male reproductive systems.

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Lei, Kai;Pan, Hui-Yun;Zhu, Ying;Chen, Wei;Lin, Chun-Ye published 《Pollution characteristics and mixture risk prediction of phenolic environmental estrogens in rivers of the Beijing-Tianjin-Hebei urban agglomeration, China》 in 2021. The article was appeared in 《Science of the Total Environment》. They have made some progress in their research.HPLC of Formula: 140-66-9 The article mentions the following:

Phenolic environmental estrogens (PEEs) are ubiquitous in most rivers worldwide and may cause potential endocrine-disrupting effects in aquatic organisms. Three typical PEEs (bisphenol A, BPA; 4-tert-octylphenol,4-t-OP; and nonylphenol, NP) were investigated in the rivers of the Beijing-Tianjin-Hebei urban agglomeration, which is the most urbanized and industrialized area in North China. The target PEEs were detected in 100% of river water samples, and the concentrations ranged from 23 to 255 ng L^-1. The concentrations of NP in most river sections were higher than those of BPA and 4-t-OP. The spatiotemporal variations in PEEs indicated that both domestic and industrial wastewater were main sources of PEEs in river water. In addition, rainfall runoff might be an important source of PEEs in the receiving waters, especially in the wet season. The ecotoxicol. risk assessment of individual PEE revealed a moderate to high risk for aquatic organisms at most sampling sites. The mixture risk prediction based on the concentration addition method indicated a potential cumulative risk of PEEs in the study area, highlighting the importance of mixture risk assessment in the aquatic environment.4-tert-Octylphenol (cas: 140-66-9) were involved in the experimental procedure.

4-tert-Octylphenol(cas: 140-66-9) is a common environmental pollutant showing weak estrogenic effects.HPLC of Formula: 140-66-9 It has been shown to cause harm to vertebrate male reproductive systems.

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Formula: C14H14O2In 2021, Jo, Junhyuk;Kim, Seonyul;Choi, Jun-Ho;Chung, Won-jin published 《A convenient pinacol coupling of diaryl ketones with B₂pin₂ via pyridine catalysis》. 《Chemical Communications (Cambridge, United Kingdom)》published the findings. The article contains the following contents:

A convenient, pyridine-boryl radical-mediated pinacol coupling of diaryl ketones is developed. In contrast to the conventional pinacol coupling that requires sensitive reducing metal, the current method employs a stable diboron reagent and pyridine Lewis base catalyst for the generation of a ketyl radical. The newly developed process is operationally simple, and the desired diols, e.g., I are produced with excellent efficiency in up to 99% yield within 1 h. The superior reactivity of diaryl ketone was observed over monoaryl carbonyl compounds and analyzed by DFT calculations, which suggests the necessity of both aromatic rings for the maximum stabilization of the transition states. The experimental procedure involved many compounds, such as rel-(1R,2S)-1,2-Diphenylethane-1,2-diol (cas: 579-43-1) .

rel-(1R,2S)-1,2-Diphenylethane-1,2-diol(cas: 579-43-1 Formula: C14H14O2) has been used in the preparation of trans-methyl meso-hydrobenzoin phosphite.

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Related Products of 599-64-4《Teaching an Old Poly(arylene ether) New Tricks: Efficient Blue Thermally Activated Delayed Fluorescence》 was published in 2019. The authors were Liu, Xinrui;Rao, Jiancheng;Li, Xuefei;Wang, Shumeng;Ding, Junqiao;Wang, Lixiang, and the article was included in《iScience》. The author mentioned the following in the article:

Polymer light-emitting diodes are attractive for optoelectronic applications owing to their brightness and ease of processing. However, often metals have to be inserted to increase the luminescence efficiency, and producing blue emitters is a challenge. Here we present a strategy to make blue thermally activated delayed fluorescence (TADF) polymers by directly embedding a small mol. blue TADF emitter into a poly(aryl ether) (PAE) backbone. Thanks to the oxygen-induced negligible electronic communication between neighboring TADF fragments, its corresponding blue delayed fluorescence can be inherited by the developed polymers. These polymers are free from metal catalyst contamination and show improved thermal stability. Through device optimization, a current efficiency of 29.7 cd/A (21.2 lm/W, 13.2%) is realized together with Commission Internationale de L′Eclairage coordinates of (0.18, 0.32). The value is competitive with blue phosphorescent polymers, highlighting the importance of the PAE backbone in achieving high-performance blue delayed fluorescence at a macromol. level. And 4-(2-Phenylpropan-2-yl)phenol (cas: 599-64-4) was used in the research process.

4-(2-Phenylpropan-2-yl)phenol(cas:599-64-4) is a natural product found in Panax ginseng.Related Products of 599-64-4 4-(2-Phenylpropan-2-yl)phenol is a useful reagent for preparing and characterizing aromatic polyphosphonates as high refractive index polymers.

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Quality Control of 2-Hexyl-1-decanolIn 2021, Kumar, M.;Charishma, K.;Sahu, K. P.;Sheoran, N.;Patel, A.;Kundu, A.;Kumar, A. published 《Rice leaf associated Chryseobacterium species: An untapped antagonistic flavobacterium displays volatile mediated suppression of rice blast disease》. 《Biological Control》published the findings. The article contains the following contents:

Rice phyllosphere-associated pigmented bacteria were characterized and identified as Chryseobacterium based on 16S rRNA gene sequencing and phenotypic fingerprinting by Biolog. Mol. phylogenetic anal. by maximum likelihood method clustered the leaf Chryseobacterium with plant or soil-associated Chryseobacterium taklimakanense (OsEp-PSA33); Chryseobacterium camaliae (OsEnb-ALM-D20, OsEnb-ALM-D11); Chryseobacterium culicis (OsEnb-ALM-C23, OsEp-PPA23, OsEp-PPA6, OsEnb-ALM-D3); and Chryseobacterium endophyticum (OsEnb-ALM-A6, OsEnb-ALM-A22). Activity testing of Chryseobacterium isolates showed excellent antifungal activity with over 80.0 mycelial growth inhibition of Magnaporthe oryzae. The Chryseobacterium endophyticum OsEnb-ALM-A6 and OsEnb-ALM-A22 showed over 90 fungal growth inhibition by volatile compounds Chem. anal. of volatiles emitted by Chryseobacterium indicated the abundance of 2-Ethyl-hexanol; 1-Hexadecene; 2-Hexyl-decanol; Heptanal; Furan-diol; and Octanal. Upon seed or seedling bacterization, Chryseobacterium endophyticum not only triggered altered growth pattern of rice but also suppressed blast disease (40.0 reduction over mock). qPCR-based transcriptional anal. showed enhanced expression of defense associated OsCEBiP, OsCERK, OsPAD4, OsNPR1.3, and OsFMO1. The volatile mediated antifungal activity and host defense induction by Chryseobacterium can be a potential alternative to fungicide-based blast management.2-Hexyl-1-decanol (cas: 2425-77-6) were involved in the experimental procedure.

2-Hexyl-1-decanol(cas: 2425-77-6) is a fatty acid that is found in the essential oils of plants and has been shown to have fungicidal properties.Quality Control of 2-Hexyl-1-decanol It has also been shown to inhibit the growth of Candida glabrata when used as a cationic surfactant.

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Sharma, Pooja;Tripathi, Sonam;Chaturvedi, Preeti;Chaurasia, Deepshi;Chandra, Ram published 《Newly isolated Bacillus sp. PS-6 assisted phytoremediation of heavy metals using Phragmites communis: Potential application in wastewater treatment》 in 2021. The article was appeared in 《Bioresource Technology》. They have made some progress in their research.Electric Literature of C16H34O The article mentions the following:

This work aimed to study Bacillus sp. PS-6 assisted phytoremediation of metals from pulp and paper industry wastewater as a novel green technique for the removal of metals of wastewater. Results revealed that heavy metal (mg L-1) contents in wastewater were reduced after in-situ phytoremediation for Fe, Cu, Zn, Cd, Mn, Ni, Pb, and As. Phragmites communis showed higher potential for the enrichment of Fe, Cu, Zn, Cd, Mn, Ni, Pb, and As in its rhizomes, roots, and shoots compared to leaves. The strain produced indole acetic acid, siderophores, and hydrolytic and ligninolytic enzymes, and resulted in nutrients solubilization. Results offer potential basis for the removal of metals from pulp and paper industry wastewater at large scale and prevention of pollution.2-Hexyl-1-decanol (cas: 2425-77-6) were involved in the experimental procedure.

2-Hexyl-1-decanol(cas: 2425-77-6) may be employed as an organic solvent to study the extraction of non-polar acidic drugs from human plasma by parallel artificial liquid membrane extraction (PALME). Electric Literature of C16H34O

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Chi, Xuelu;Shao, Yiwei;Pan, Minghui;Yang, Qingyu;Yang, Yan;Zhang, Xiaomei;Ai, Nasi;Sun, Baoguo published 《Distinction of volatile flavor profiles in various skim milk products via HS-SPME-GC-MS and E-nose》 in 2021. The article was appeared in 《European Food Research and Technology》. They have made some progress in their research.Application of 2425-77-6 The article mentions the following:

Volatile flavor profile of skim milk relates to product quality and consumer liking. The volatile compositions of different skim milk products are challenging to discriminate due to subtle constituents and inconspicuous peculiarities. This study develops a correlative anal. protocol for the characterization and differentiation of volatile flavor components in various skim milk products via headspace solid-phase micro-extraction gas chromatog.-mass spectrometry (HS-SPME-GC-MS) and electronic nose (E-nose) with multivariate statistical anal. Sixty-three volatile flavor components were identified in six skim milk products, which were paired into pasteurized skim milk, ultra-high-temperature skim milk, and modified skim milk, resp. Distinguishable variation trends were observed upon the aroma response values of skim milk samples through the solid-state E-nose sensors. The results of principal component anal., cluster heatmap anal. and Venn diagram anal. showed that significant distinctions in varying degrees among the six skim milk products could be presented in both volatile flavor composition and aroma release distribution. The correlative anal. by partial least squares regression indicated an adequate combination of HS-SPME-GC-MS and E-nose for the differentiation and classification of volatile flavor profiles in skim milk products. These findings provide an insightful perspective for the efficient flavor evaluation of fluid skim milk.2-Hexyl-1-decanol (cas: 2425-77-6) were involved in the experimental procedure.

2-Hexyl-1-decanol(cas: 2425-77-6) is a fatty acid that is found in the essential oils of plants and has been shown to have fungicidal properties.Application of 2425-77-6 It has also been shown to inhibit the growth of Candida glabrata when used as a cationic surfactant.

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