Tag: 100-200

Synthesis of macrocyclic molecular rods as potential electronic devices was written by Blaszczyk, Alfred;Chadim, Martin;von Haenisch, Carsten;Mayor, Marcel. And the article was included in European Journal of Organic Chemistry in 2006.Application In Synthesis of Sodium 2-methyl-2-propanethiolate This article mentions the following:

The design and synthesis of the macrocycles I (R = H, NO₂) as model compounds for the investigation of neg. differential conductance phenomena in mol. junctions are reported. I (R = H, NO₂) comprise a mol. rod subunit consisting of three ethynyl-linked Ph rings. While the rotational freedom along the rod axis of both terminal Ph rings is limited by the macrocyclic frame, the central Ph ring is revolving. The rod substructure is terminally functionalized with acetyl-protected thiol groups to enable its immobilization between gold contacts. The central Ph ring is functionalized with one and two nitro groups for I (R = H, NO₂). The nitro groups are of particular importance as (i) both macrocycles are model compounds to investigate a hypothetical intramol. interaction of the nitro group with the opposite macrocyclic subunits and (ii) the nitro group(s) result in limited thermal stability of the compounds due to the intramol. rearrangement to macrocycles comprising isatogen subunits. These highly functionalized macrocycles have been assembled by acetylene scaffolding strategies in combination with functional group transformation chem. In the experiment, the researchers used many compounds, for example, Sodium 2-methyl-2-propanethiolate (cas: 29364-29-2Application In Synthesis of Sodium 2-methyl-2-propanethiolate).

Sodium 2-methyl-2-propanethiolate (cas: 29364-29-2) belongs to alcohols. A strong base can deprotonate an alcohol to yield an alkoxide ion (R―O−). For example, sodamide (NaNH2), a very strong base, abstracts the hydrogen atom of an alcohol. A multistep synthesis may use Grignard-like reactions to form an alcohol with the desired carbon structure, followed by reactions to convert the hydroxyl group of the alcohol to the desired functionality.Application In Synthesis of Sodium 2-methyl-2-propanethiolate

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Palladium-catalyzed one-pot synthesis of 2-substituted quinazolin-4(3H)-ones from o-nitrobenzamide and alcohols was written by Wang, Ke;Chen, Hao;Dai, Xinyan;Huang, Xupeng;Feng, Zhiqiang. And the article was included in RSC Advances in 2021.Recommanded Product: 6-Methyl-2-pyridinemethanol This article mentions the following:

Palladium-catalyzed 2-substituted quinazolin-4(3H)-one formation from readily available o-nitrobenzamides and alcs. using hydrogen transfer was described. Various quinazolin-4(3H)-ones were obtained in good to high yields. The cascade reaction including alc. oxidation, nitro reduction, condensation, and dehydrogenation occurs without any added reducing or oxidizing agent. In the experiment, the researchers used many compounds, for example, 6-Methyl-2-pyridinemethanol (cas: 1122-71-0Recommanded Product: 6-Methyl-2-pyridinemethanol).

6-Methyl-2-pyridinemethanol (cas: 1122-71-0) belongs to alcohols. A strong base can deprotonate an alcohol to yield an alkoxide ion (R―O−). For example, sodamide (NaNH2), a very strong base, abstracts the hydrogen atom of an alcohol. Alcohols may be oxidized to give ketones, aldehydes, and carboxylic acids. These functional groups are useful for further reactions. Oxidation of organic compounds generally increases the number of bonds from carbon to oxygen (or another electronegative element, such as a halogen), and it may decrease the number of bonds to hydrogen.Recommanded Product: 6-Methyl-2-pyridinemethanol

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Alcohol – Wikipedia,
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Physiological and metabolomics responses of Hydrangea macrophylla (Thunb.) Ser. and Hydrangea strigosa Rehd. to lead exposure was written by Jin, Jing;Song, Ziyi;Zhao, Bing;Zhang, Yuyu;Wang, Ruirui. And the article was included in Ecotoxicology and Environmental Safety in 2022.Electric Literature of C4H10O3 This article mentions the following:

Hydrangea is a potential remediation plant for lead (Pb) pollution. Plant roots communicate with soil through the release of root exudates. It is crucial to study rhizoremediation mechanisms to understand the response of root exudates to contamination stress. Here, we investigated the physiol. responses and metabolomic profiling of two Hydrangea species, a horticultural cultivar (Hydrangea macrophylla (Thunb.) Ser.) and a wild type (Hydrangea strigosa Rehd.), under Pb-free and Pb-stressed conditions for 50 days. The results showed that Pb treatment adversely affected the biomass and root growth of the two species. H. strigosa was a Pb-tolerant species with higher superoxide dismutase (SOD), peroxidase (POD) and catalase (CAT) activities and more ascorbic acid (AsA) content in roots. Metabolomic profiling showed that 181 and 169 compounds were identified in H. macrophylla and H. strigosa root exudates, resp., among which 18 showed significant differences between H. macrophylla and H. strigosa under Pb exposure. H. strigosa showed significantly (P < 0.05) higher secretion of sucrose, glycolic acid, and nonanoic acid than H. macrophylla after Pb treatment. Pb stress promoted fatty acid metabolism in H. strigosa, suppressed amino acid metabolism in H. macrophylla, and promoted a higher carbohydrate metabolism in H. strigosa compared with H. macrophylla. This study provides a possible mechanism for the high Pb absorption potential of Hydrangea. In the experiment, the researchers used many compounds, for example, 2,2′-Oxybis(ethan-1-ol) (cas: 111-46-6Electric Literature of C4H10O3).

2,2′-Oxybis(ethan-1-ol) (cas: 111-46-6) belongs to alcohols. Under appropriate conditions, inorganic acids also react with alcohols to form esters. To form these esters, a wide variety of specialized reagents and conditions can be used. Grignard and organolithium reagents are powerful tools for organic synthesis, and the most common products of their reactions are alcohols.Electric Literature of C4H10O3

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Ferrocene based chiral binuclear η⁶-benzene-Ru(II)-phosphinite complexes: Synthesis, characterization and catalytic activity in asymmetric reduction of ketones was written by Abdlhmed Al-bayati, Yaser W.;Karakas, Duygu Elma;Meric, Nermin;Aydemir, Murat;Durap, Feyyaz;Baysal, Akin. And the article was included in Applied Organometallic Chemistry in 2018.Electric Literature of C8H9FO This article mentions the following:

In the present study, a series of chiral C₂-sym. ferrocenyl based binuclear η⁶-benzene-Ru(II) complexes bearing diphenylphosphinite and diisopropylphosphinite moieties have been synthesized. The new binuclear η⁶-benzene-Ru(II)-phosphinite complexes were characterized based on NMR (¹H, ¹³C, ³¹P-NMR), FT-IR spectroscopy and elemental anal. Then, these complexes have been screened as catalytic precursors in the transfer hydrogenation of acetophenone with 2-propanol as both the hydrogen source and solvent in the presence of KOH. The corresponding optically active secondary alcs. were obtained in excellent conversion rates between 96 and 99% and moderate to good enantioselectivities (up to 78% ee). The complex 5 was the most efficient catalyst among the four new complexes investigated herein. In the experiment, the researchers used many compounds, for example, (S)-1-(2-Fluorophenyl)ethanol (cas: 171032-87-4Electric Literature of C8H9FO).

(S)-1-(2-Fluorophenyl)ethanol (cas: 171032-87-4) belongs to alcohols. The oxygen atom of the strongly polarized O―H bond of an alcohol pulls electron density away from the hydrogen atom. This polarized hydrogen, which bears a partial positive charge, can form a hydrogen bond with a pair of nonbonding electrons on another oxygen atom. Under carefully controlled conditions, simple alcohols can undergo intermolecular dehydration to give ethers. This reaction is effective only with methanol, ethanol, and other simple primary alcohols.Electric Literature of C8H9FO

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Alcohol – Wikipedia,
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Evolution of chiral Lewis basic N-formamide as highly effective organocatalyst for asymmetric reduction of both ketones and ketimines with an unprecedented substrate scope was written by Zhou, Li;Wang, Zhouyu;Wei, Siyu;Sun, Jian. And the article was included in Chemical Communications (Cambridge, United Kingdom) in 2007.Computed Properties of C8H9ClO This article mentions the following:

L-Pipecolinic acid derived Lewis basic N-formamide (I) has been developed as a first highly effective catalyst for the asym. reduction of aromatic and aliphatic ketones as well as aromatic and aliphatic ketimines in good to high enantioselectivity. In the experiment, the researchers used many compounds, for example, (R)-1-(3-Chlorophenyl)ethanol (cas: 120121-01-9Computed Properties of C8H9ClO).

(R)-1-(3-Chlorophenyl)ethanol (cas: 120121-01-9) belongs to alcohols. Under appropriate conditions, inorganic acids also react with alcohols to form esters. To form these esters, a wide variety of specialized reagents and conditions can be used. Converting an alcohol to an alkene requires removal of the hydroxyl group and a hydrogen atom on the neighbouring carbon atom. Dehydrations are most commonly carried out by warming the alcohol in the presence of a strong dehydrating acid, such as concentrated sulfuric acid.Computed Properties of C8H9ClO

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Alcohol – Wikipedia,
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Pyridyl unit in host compounds was written by Newcomb, Martin;Gokel, George W.;Cram, Donald J.. And the article was included in Journal of the American Chemical Society in 1974.Reference of 1122-71-0 This article mentions the following:

Eight multiheteromacrocycles, e.g. I, II, and III, were prepared Thus, the pyridine IV (R = H, R1 = OH) was treated with NaH and IV (R = H, R1 = Cl) and the resulting bispyridine V (R = H) was oxidized followed by treatment with Ac2O and hydrolysis to give V (R = OH), which with IV (R = R1 = Br) gave II. The pKa values of the monoprotonated macrocycles were determined II forms a 1:1 complex with Me3CN+H3SCN-. In the experiment, the researchers used many compounds, for example, 6-Methyl-2-pyridinemethanol (cas: 1122-71-0Reference of 1122-71-0).

6-Methyl-2-pyridinemethanol (cas: 1122-71-0) belongs to alcohols. Under appropriate conditions, inorganic acids also react with alcohols to form esters. To form these esters, a wide variety of specialized reagents and conditions can be used. A multistep synthesis may use Grignard-like reactions to form an alcohol with the desired carbon structure, followed by reactions to convert the hydroxyl group of the alcohol to the desired functionality.Reference of 1122-71-0

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Nonlinear optical organic co-crystals of merocyanine dyes and phenolic derivatives with short hydrogen bonds was written by Bosshard, Christian;Pan, Feng;Wong, Man Shing;Manetta, Sabine;Spreiter, Rolf;Cai, Chengzhi;Gunter, Peter;Gramlich, Volker. And the article was included in Chemical Physics in 1999.HPLC of Formula: 60463-12-9 This article mentions the following:

We investigated the co-crystallization of merocyanine dyes M (M : RN⁺C₅H₄CH:CHC₆H₄O^–, M1: R = Me, M2: R = HOCH₂CH₂) with phenolic and aniline derivatives and show that the short or very short hydrogen bond between the two phenolic oxygen atoms which lead to a self-assembly of the M dyes and phenol derivatives is the key steering force for the cocrystn. process. The cocrystal formation was studied by m.p. determination, by second-harmonic generation using the Kurtz and Perry powder test, and X-ray structural anal. We present detailed results on the growth, polymorphism, and nonlinear optical properties of cocrystals of derivatives of M1 (M2) and m-nitrophenol (mNP) and cocrystals of M2 and Me 2,4-dihydroxybenzoate (MDB). Three phases of the cocrystal M2·mNP and three phases of the cocrystal M2·MDB were found. Both M2·MDB(I) and (II) have the same crystal structure (space group symmetry Cc determined by X-ray diffraction), but show different linear and nonlinear optical properties. This unusual property in the co-crystals of M2·MDB(I) and (II) may be caused by a different proton location of the short hydrogen bond (O-H-O) in the aggregation between M2 and MDB which could not be resolved by X-ray diffraction. In the experiment, the researchers used many compounds, for example, 3-(Hydroxymethyl)-4-nitrophenol (cas: 60463-12-9HPLC of Formula: 60463-12-9).

3-(Hydroxymethyl)-4-nitrophenol (cas: 60463-12-9) belongs to alcohols. Similar to water, an alcohol can be pictured as having an sp3 hybridized tetrahedral oxygen atom with nonbonding pairs of electrons occupying two of the four sp3 hybrid orbitals. Converting an alcohol to an alkene requires removal of the hydroxyl group and a hydrogen atom on the neighbouring carbon atom. Dehydrations are most commonly carried out by warming the alcohol in the presence of a strong dehydrating acid, such as concentrated sulfuric acid.HPLC of Formula: 60463-12-9

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Alcohol – Wikipedia,
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Cobalt-catalyzed alkoxycarbonylation of ethers: Direct synthesis of α-oxy esters from phenols and alcohols was written by Wang, Le-Cheng;Xu, Jian-Xing;Wu, Xiao-Feng. And the article was included in Journal of Catalysis in 2022.Formula: C10H20O This article mentions the following:

A cobalt-catalyzed direct alkoxycarbonylation of ethers (such as THF, 1,4-dioxane, ethoxyethane, etc.) has been accomplished. This new catalytic system allows the use of ethers, important building blocks in organic synthesis, as the carbonylation substrates. A variety of phenols and alcs. ROH was transformed to the corresponding α-oxy ester derivatives ROC(O)R¹ (R¹ = oxolan-2-yl, 1,4-dioxan-2-yl, 1-ethoxyethyl, etc.; R = Ph, naphthalen-2-yl, pyridin-3-yl, adamantan-1-yl, etc.) in high yields with excellent functional group tolerance. In addition, several pharmaceutical and bioactive mol. related compounds were also suitable substrates for this carbonylation process, and the target products were obtained in good yields. In the experiment, the researchers used many compounds, for example, (1R,2S,5R)-2-Isopropyl-5-methylcyclohexanol (cas: 2216-51-5Formula: C10H20O).

(1R,2S,5R)-2-Isopropyl-5-methylcyclohexanol (cas: 2216-51-5) belongs to alcohols. Alcohols are weak acids. The most acidic simple alcohols (methanol and ethanol) are about as acidic as water, and most other alcohols are somewhat less acidic. Grignard and organolithium reagents are powerful tools for organic synthesis, and the most common products of their reactions are alcohols.Formula: C10H20O

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Novel thioether Schiff base transition metal complexes: Design, synthesis, characterization, molecular docking, computational, biological and catalytic studies was written by Singh, Anmol;Gogoi, Himadri Priya;Barman, Pranjit;Guha, Ankur Kanti. And the article was included in Applied Organometallic Chemistry in 2022.Category: alcohols-buliding-blocks This article mentions the following:

A series of novel copper(II), nickel(II), zinc(II) and cobalt(II) Schiff base metal complexes were synthesized by the reaction of 2-(benzylthio)aniline with pyrrole-2-carboxaldehyde and characterized by FT-IR, UV-visible, elemental analyses, ¹H-NMR, magnetic susceptibility and ESI-MS. The Schiff base ligand posed as an NS-bidentate ligand, confirming the synthesis of metal complexes with the suggested structure, according to the spectrum anal. data. All the complexes acquire square planar geometry. Furthermore, the DFT method was utilized to conduct computational analyses of metal complexes. The spectroscopic (UV-Vis and fluorescence) techniques were employed to probe the binding nature of calf thymus-DNA binding to metal complexes. The metal complexes interact with DNA through intercalative mode, according to the spectroscopic titration data. The antioxidant properties of metal complexes were evaluated using their reducing ability and free radical scavenging activity of DPPH. The antioxidant property is high in isolated complexes. The in vitro anti-inflammatory efficacy of all complexes has also been studied. All the metal complexes exhibited effective anti-inflammatory activity and can be used as synthetic drugs. The synthesized copper(II) complex exhibits excellent catalytic activities for the transformation reaction of alc. to aldehyde in the presence of hydrogen peroxide. The interaction of metal complexes with active sites of the B-DNA (1-BNA) and 6-COX (COX 2) was studied using docking studies. In the experiment, the researchers used many compounds, for example, (4-Chlorophenyl)methanol (cas: 873-76-7Category: alcohols-buliding-blocks).

(4-Chlorophenyl)methanol (cas: 873-76-7) belongs to alcohols. The oxygen atom of the strongly polarized O―H bond of an alcohol pulls electron density away from the hydrogen atom. This polarized hydrogen, which bears a partial positive charge, can form a hydrogen bond with a pair of nonbonding electrons on another oxygen atom. A multistep synthesis may use Grignard-like reactions to form an alcohol with the desired carbon structure, followed by reactions to convert the hydroxyl group of the alcohol to the desired functionality.Category: alcohols-buliding-blocks

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Alcohol – Wikipedia,
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Nanoemulsion of Myrtus communis essential oil and evaluation of its larvicidal activity against Anopheles stephensi was written by Firooziyan, Samira;Osanloo, Mahmoud;Basseri, Hamid Reza;Moosa-Kazemi, Seyed Hasan;Mohammadzadeh Hajipirloo, Habib;Amani, Amir;Sedaghat, Mohammad Mehdi. And the article was included in Arabian Journal of Chemistry in 2022.Related Products of 499-75-2 This article mentions the following:

Excessive use of chem. insecticides has caused environmental pollution and vector resistance. Herbal essential oils with larvicidal properties are good alternatives to synthetic insecticides. In this study, larvicide properties of Myrtus communis essential oil and its nanoemulsion against Anopheles stephensi were investigated. Components of Myrtus communis essential oil were identified by GC-MS. Nanoemulsion of essential oil was made with Tween 80, Span 20, and water. Dynamic light scattering (DLS) and transmission electron microscopy (TEM) determined particle size and morphol. of nanoemulsions. The larvicide activity compared with bulk essential oil. A total of 107 M. communis essential oil compounds were discovered. The morphol. of a selected nanoemulsion was spherical. LC50 and LC90 of M. communis essential oil were calculated as 26.1 and 46.2 μg/mL, resp. The larvicide activity of nanoemulsion increased by 40% compared to the bulk essential oil. The nanoemulsion′s larvicide activity (100%) lasted up to 3 days, while the essential oil had larvicide properties only for up to 24 h. Myrtus communis essential oil was found to be an effective larvicide and classified as an active larvicide. The residual efficacy of the nanoformulation of M. communis significantly increased compared with the bulk essential oil. In the experiment, the researchers used many compounds, for example, 5-Isopropyl-2-methylphenol (cas: 499-75-2Related Products of 499-75-2).

5-Isopropyl-2-methylphenol (cas: 499-75-2) belongs to alcohols. Under appropriate conditions, inorganic acids also react with alcohols to form esters. To form these esters, a wide variety of specialized reagents and conditions can be used. Alcohols may be oxidized to give ketones, aldehydes, and carboxylic acids. These functional groups are useful for further reactions. Oxidation of organic compounds generally increases the number of bonds from carbon to oxygen (or another electronegative element, such as a halogen), and it may decrease the number of bonds to hydrogen.Related Products of 499-75-2

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts