Tag: 100-200

Evaluation of antimicrobial and cytotoxic effects of Echinacea and Arctium extracts and Zataria essential oil was written by Yazdanian, Mohsen;Rostamzadeh, Pouya;Alam, Mostafa;Abbasi, Kamyar;Tahmasebi, Elahe;Tebyaniyan, Hamid;Ranjbar, Reza;Seifalian, Alexander;Moghaddam, Mehrdad Moosazadeh;Kahnamoei, Majid Balaei. And the article was included in AMB Express in 2022.SDS of cas: 499-75-2 This article mentions the following:

Dental caries and oral infections have become a widespread issue in the modern world. This study aimed to investigate the antibacterial, antifungal, and cytotoxicity characteristics of the extracts of Echinacea purpura, Arctium lappa, and the essential oil of Zataria multiflora as a potential herbal mouthwash. The essential oil of Z. multiflora leaves and the extracts of E. purpurea and A. lappa roots were prepared The characterization was carried out by GC-MS and also, total phenol and flavonoid were assed for all three samples. The antimicrobial and anti-biofilm effects were evaluated against Streptococcus mutans, Streptococcus mitis, Streptococcus salivarius, Lactobacillus acidophilus, Escherichia coli, Staphylococcus aureus, and Candida albicans. The cytotoxic effect of the samples was evaluated on HEK 293 and HDFa cells by MTT test. Thymol and carvacrol contents in EO of Z. multiflora were measured at 31% and 42.2%, resp. A. lappa had the lowest total phenolic and flavonoid value among the samples. On the other hand, the total phenolic content of Z. multiflora and the total flavonoid content of E. purpurea were the highest. The MIC values of Zataria, Arctium, and Echinacea against S. mutans were 0.011% volume/volume, 187.5 mg/mL, and 93.75 mg/mL, while MBC were 0.011% volume/volume, 375 mg/mL, and 187.5 mg/mL, resp. The formulation showed bactericidal activity against S. mutans in the concentration of 5.86 mg/mL for Echinacea and Burdock extracts and 0.08μl/mL for EO of Zataria. The formulation significantly affected microbial biofilm formation and induced biofilm degradation The cell viability percentages were higher than 50% during 24 and 48 h. The formulation had a significant antimicrobial effect on cariogenic bacteria and C. albicans, with the lowest cytotoxic effects. Therefore, this formulation can be an appropriate candidate for mouthwash. In the experiment, the researchers used many compounds, for example, 5-Isopropyl-2-methylphenol (cas: 499-75-2SDS of cas: 499-75-2).

5-Isopropyl-2-methylphenol (cas: 499-75-2) belongs to alcohols. Alcohols are among the most common organic compounds. They are used as sweeteners and in making perfumes, are valuable intermediates in the synthesis of other compounds, and are among the most abundantly produced organic chemicals in industry. The most common reactions of alcohols can be classified as oxidation, dehydration, substitution, esterification, and reactions of alkoxides.SDS of cas: 499-75-2

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Characterization of key aroma compounds in traditional beef soup was written by Wang, Lin;Li, Cong;Al-Dalali, Sam;Liu, Yiyang;Zhou, Hui;Chen, Conggui;Xu, Baocai;Wang, Ying. And the article was included in Journal of Food Composition and Analysis in 2022.Reference of 3391-86-4 This article mentions the following:

This study aimed to identify the characteristic aroma compounds of beef soup and analyze the differences between their aroma. Seven beef soup samples were analyzed by sensory evaluation combined with gas chromatog.-mass spectrometry (GC-MS) and electronic nose (E-nose). A total of 80 volatile compounds were identified, and seven key aroma compounds in beef soup samples were determined by odor activity value, sensory evaluation, aroma recombination and omission experiments They were linalool, (E)-3,7-dimethyl-2,6-octadien-1-ol, nonanal, (E)-2-octenal, 3,7-dimethyl-2,6-octadienal, 2-acetylthiazole and estragole. The panelists described the organoleptic characteristics of beef soup as beef meaty, spice, fatty, caramel, and roasted. GC-MS and E-nose combined with principal component anal. showed different aroma profiles among beef soup samples. A total of 30 potential differential markers were screened by partial least squares discriminant anal. The difference between samples was mainly caused by the type and content of compounds In the experiment, the researchers used many compounds, for example, Oct-1-en-3-ol (cas: 3391-86-4Reference of 3391-86-4).

Oct-1-en-3-ol (cas: 3391-86-4) belongs to alcohols. Under appropriate conditions, inorganic acids also react with alcohols to form esters. To form these esters, a wide variety of specialized reagents and conditions can be used. The most common reactions of alcohols can be classified as oxidation, dehydration, substitution, esterification, and reactions of alkoxides.Reference of 3391-86-4

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Alcohol – Wikipedia,
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A Ferrocene-Based NH-Free Phosphine-Oxazoline Ligand for Iridium-Catalyzed Asymmetric Hydrogenation of Ketones was written by Wang, Yanzhao;Yang, Guoqiang;Xie, Fang;Zhang, Wanbin. And the article was included in Organic Letters in 2018.Synthetic Route of C8H9ClO This article mentions the following:

A new type of ferrocene-based phosphine-oxazoline ligand has been prepared over a few simple steps. An iridium complex of this ligand is air stable and exhibits excellent performance for the asym. hydrogenation of simple ketones (up to 98% yield, up to 99% ee, and 20000 S/C). Exo-α,β-unsaturated cyclic ketones could be regiospecifically hydrogenated to give chiral allylic alcs. with good results. This study indicates that P,N-ligands can also efficiently promote Ir-catalyzed asym. hydrogenation without NH-hydrogen-bonding assistance. In the experiment, the researchers used many compounds, for example, (R)-1-(3-Chlorophenyl)ethanol (cas: 120121-01-9Synthetic Route of C8H9ClO).

(R)-1-(3-Chlorophenyl)ethanol (cas: 120121-01-9) belongs to alcohols. Alcohols are weak acids. The most acidic simple alcohols (methanol and ethanol) are about as acidic as water, and most other alcohols are somewhat less acidic. Grignard and organolithium reagents are powerful tools for organic synthesis, and the most common products of their reactions are alcohols.Synthetic Route of C8H9ClO

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Influence of processing conditions on the aroma profile of Litopenaeus vannamei by SPME-GC-MS was written by Duppeti, Haritha;Kempaiah, Bettadaiah Bheemanakere;Manjabhatta, Sachindra Nakkarike. And the article was included in Flavour and Fragrance Journal in 2022.Quality Control of Oct-1-en-3-ol This article mentions the following:

This study reports the aroma profile of Litopenaeus vannamei under different processing conditions such as raw, boiled, hot air dried, microwave dried and roasted using SPME-GC-MS. A total of 86 volatile compounds were identified, among which 38 compounds reported as aroma-active compounds (AAC) having the odor activity value (OAV) greater than one. The microwave-dried shrimp meat (MSM) exhibited the highest summation of odor activity value, and roasted shrimp meat (RSM) showed the highest concentration of aroma-active compounds (3448.78 μg/g). The partial least square regression (PLSR) anal. and cluster anal. (CA) showed that MSM and RSM are related to each other in their aroma characteristics while boiled shrimp meat (BSM) is different than these samples. The results of this study illustrate the typical volatile markers and the impact of processing methods on flavor generation in L. vannamei, which should be examined for the assessment of its freshness and product development based on shrimp flavor. In the experiment, the researchers used many compounds, for example, Oct-1-en-3-ol (cas: 3391-86-4Quality Control of Oct-1-en-3-ol).

Oct-1-en-3-ol (cas: 3391-86-4) belongs to alcohols. Alcohols are among the most common organic compounds. They are used as sweeteners and in making perfumes, are valuable intermediates in the synthesis of other compounds, and are among the most abundantly produced organic chemicals in industry. Tertiary alcohols cannot be oxidized at all without breaking carbon-carbon bonds, whereas primary alcohols can be oxidized to aldehydes or further oxidized to carboxylic acids.Quality Control of Oct-1-en-3-ol

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Alcohol – Wikipedia,
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Chemoselective Activation of Diethyl Phosphonates: Modular Synthesis of Biologically Relevant Phosphonylated Scaffolds was written by Adler, Pauline;Pons, Amandine;Li, Jing;Heider, Joerg;Brutiu, Bogdan R.;Maulide, Nuno. And the article was included in Angewandte Chemie, International Edition in 2018.Application In Synthesis of Sodium 2-methyl-2-propanethiolate This article mentions the following:

Phosphonates have garnered considerable attention for years owing to both their singular biol. properties and their synthetic potential. State-of-the-art methods for the preparation of mixed phosphonates, phosphonamidates, phosphonothioates, and phosphinates rely on harsh and poorly selective reaction conditions. We report herein a mild method for the modular preparation of phosphonylated derivatives, several of which exhibit interesting biol. activities, that is based on chemoselective activation with triflic anhydride. This procedure enables flexible and even iterative substitution with a broad range of O, S, N, and C nucleophiles. In the experiment, the researchers used many compounds, for example, Sodium 2-methyl-2-propanethiolate (cas: 29364-29-2Application In Synthesis of Sodium 2-methyl-2-propanethiolate).

Sodium 2-methyl-2-propanethiolate (cas: 29364-29-2) belongs to alcohols. Because alcohols are easily synthesized and easily transformed into other compounds, they serve as important intermediates in organic synthesis. Grignard and organolithium reagents are powerful tools for organic synthesis, and the most common products of their reactions are alcohols.Application In Synthesis of Sodium 2-methyl-2-propanethiolate

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Alcohol – Wikipedia,
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Aerobic oxidation of primary alcohols catalyzed by copper complexes of 1,10-phenanthroline-derived ligands was written by Das, Oindrila;Paine, Tapan Kanti. And the article was included in Dalton Transactions in 2012.Name: 6-Methyl-2-pyridinemethanol This article mentions the following:

Five copper complexes [(L¹)₂Cu(H₂O)](ClO₄)₂ (1), [(L¹)Cu(H₂O)₃](ClO₄)₂ (1a), [(L³)₂Cu(H₂O)](ClO₄)₂ (2), [(L⁵)₂Cu(H₂O)](ClO₄)₂ (3) and [(L⁶)₂Cu](ClO₄) (4) (where L¹ = 1,10-phenanthroline, L³ = 1,10-phenanthroline-5,6-dione, L⁵ = 1,10-phenanthrolinefuroxan and L⁶ = 2,9-dimethyl-1,10-phenanthrolinefuroxan), and in situ prepared copper complexes of 2,9-dimethyl-1,10-phenanthroline (L²) or 2,9-dimethyl-1,10-phenanthrolinedione (L⁴) were used for aerial oxidation of primary alcs. to the corresponding aldehydes under ambient conditions. The copper catalysts have been found to catalyze a series of primary alcs. including one secondary alc. with moderate turnover numbers and selectivity towards primary alcs. Copper(ii) complexes 1 (or 1a) and 2 were found to be the better catalysts among all other systems explored in this study. A copper(ii)-superoxo species is implicated to initiate the oxidation reaction. Structural and electronic factors of 1,10-phenanthroline-based ligands affecting the catalytic results for aerial oxidation of alcs. are discussed. In the experiment, the researchers used many compounds, for example, 6-Methyl-2-pyridinemethanol (cas: 1122-71-0Name: 6-Methyl-2-pyridinemethanol).

6-Methyl-2-pyridinemethanol (cas: 1122-71-0) belongs to alcohols. Alcohols are among the most common organic compounds. They are used as sweeteners and in making perfumes, are valuable intermediates in the synthesis of other compounds, and are among the most abundantly produced organic chemicals in industry. The most common reactions of alcohols can be classified as oxidation, dehydration, substitution, esterification, and reactions of alkoxides.Name: 6-Methyl-2-pyridinemethanol

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Unsymmetrical triazolylnaphthyridinylpyridine bridged highly active copper complexes supported on reduced graphene oxide and their application in water was written by Hu, Wenkang;Zhang, Yilin;Zhu, Haiyan;Ye, Dongdong;Wang, Dawei. And the article was included in Green Chemistry in 2019.Reference of 1777-82-8 This article mentions the following:

A novel unsym. triazolylnaphthyridinylpyridine ligand was designed and synthesized, and employed in the synthesis of a heterogeneous copper complex on reduced graphene oxide. The resulting copper composite was characterized by SEM, TEM, XPS and energy dispersive x-ray spectroscopy (EDX). This supported copper catalyst containing unsym. triazolylnaphthyridinylpyridine (only 0.1 mol%) showed excellent catalytic activity in water with good recyclability. Various functionalized quinoline derivatives were successfully synthesized in high yields through the green strategy in water. Other heterocyclic compounds, such as pyridine, 2-(pyridin-2-yl)quinoline, 1,8-naphthyridine, 5,6-dihydronaphtho[1,2-b][1,8]naphthyridine and 2-(pyridin-2-yl)-1,8-naphthyridine derivatives, were achieved in water with >80% yields. Mechanism studies revealed that this transformation occurs via dehydrogenation, condensation, and transfer hydrogenation and dehydrogenation processes which was supported by a deuterium labeling experiment In the experiment, the researchers used many compounds, for example, (2,4-Dichlorophenyl)methanol (cas: 1777-82-8Reference of 1777-82-8).

(2,4-Dichlorophenyl)methanol (cas: 1777-82-8) belongs to alcohols. Because alcohols are easily synthesized and easily transformed into other compounds, they serve as important intermediates in organic synthesis. Under carefully controlled conditions, simple alcohols can undergo intermolecular dehydration to give ethers. This reaction is effective only with methanol, ethanol, and other simple primary alcohols.Reference of 1777-82-8

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Alcohol – Wikipedia,
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Acrylamide formation and aroma evaluation of fried pepper sauce under different exogenous Maillard reaction conditions was written by Song, Yuting;Ding, Zhuhong;Peng, Yuzhu;Wang, JiaYing;Zhang, Ting;Yu, Yihong;Wang, Yi. And the article was included in Food Chemistry: X in 2022.Product Details of 3391-86-4 This article mentions the following:

To explore the impact of the Maillard reaction on fried pepper sauce (FPS) flavor and safety quality, acrylamide and volatile organic compounds (VOCs) were measured in FPS. Acrylamide was detected in 10 Maillard treated groups and a total of 110 VOCs were identified, mainly aldehydes, ketones, alcs., acids, etc., but the content of each group differed. Partial least squares discriminant anal. showed that acrylamide in white sugar-sodium glutamate group and xylose-soy peptide group processing accumulated most acrylamide and least VOCs; Lactose-glycine, lactose-cysteine, lactose-soy peptide, and white sugar-glycine groups were pos. correlated with typical Maillard reaction product (2,3-Dihydro-3,5-dihydroxy-6-methyl-4(H)-pyran-4-One); Xylose-glycine, xylose-cysteine, and white sugar-cysteine groups were weakly correlated with typical products, but pos. correlated with most VOCs, whereas white sugar-cysteine group lipids showed high oxidation levels. Although white sugar-soy peptide group is not harmful on acrylamide, it has little correlation with VOCs with large responses. Conventional excipient group aroma is relatively simple with a fresh fatty taste, whereas xylose-glycine, xylose-cysteine, xylose-soy peptide, lactose-glycine, and white sugar-cysteine groups all present basic fresh and fatty tastes; lactose-cysteine group has a fruity base note; and lactose-soybean peptide, white sugar-glycine, and white sugar-soybean peptide groups have a fruity base note on an unpleasant fatty aroma. Therefore, processing different exogenous Maillard reaction substrates can achieve FPS aroma regulation and reduce acrylamide harm. In the experiment, the researchers used many compounds, for example, Oct-1-en-3-ol (cas: 3391-86-4Product Details of 3391-86-4).

Oct-1-en-3-ol (cas: 3391-86-4) belongs to alcohols. Alcohols are among the most common organic compounds. They are used as sweeteners and in making perfumes, are valuable intermediates in the synthesis of other compounds, and are among the most abundantly produced organic chemicals in industry. Secondary alcohols are easily oxidized without breaking carbon-carbon bonds only as far as the ketone stage. No further oxidation is seen except under very stringent conditions.Product Details of 3391-86-4

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Alcohol – Wikipedia,
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Proton-ligand stability constants of substituted ortho-hydroxyacetophenones and ortho-hydroxypropiophenones was written by Kamat, P. V.;Datar, M. G.. And the article was included in Journal of the Indian Chemical Society in 1970.Recommanded Product: 2′,6′-Dihydroxy-4′-methylacetophenone This article mentions the following:

Proton-ligand stability constant of substituted o-hydroxyacetophenones and o-hydroxypropiophenones were determined at 30° by a potentiometric method by the Bjerrum-Calvin titration technique at constant ionic strength ∼0.1M NaClO4. Correlation between the effect and the position of substituents in the benzene nucleus is discussed. In the experiment, the researchers used many compounds, for example, 2′,6′-Dihydroxy-4′-methylacetophenone (cas: 1634-34-0Recommanded Product: 2′,6′-Dihydroxy-4′-methylacetophenone).

2′,6′-Dihydroxy-4′-methylacetophenone (cas: 1634-34-0) belongs to alcohols. Alcohols are weak acids. The most acidic simple alcohols (methanol and ethanol) are about as acidic as water, and most other alcohols are somewhat less acidic. Alcohols may be oxidized to give ketones, aldehydes, and carboxylic acids. These functional groups are useful for further reactions. Oxidation of organic compounds generally increases the number of bonds from carbon to oxygen (or another electronegative element, such as a halogen), and it may decrease the number of bonds to hydrogen.Recommanded Product: 2′,6′-Dihydroxy-4′-methylacetophenone

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Alcohol – Wikipedia,
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ansa-Ruthenium(II) Complexes of DPEN-SO₂N(Me)(CH₂)_n(η⁶-aryl) Conjugate Ligands for Asymmetric Transfer Hydrogenation of Aryl Ketones was written by Kisic, Andrea;Stephan, Michel;Mohar, Barbara. And the article was included in Advanced Synthesis & Catalysis in 2014.Application of 171032-87-4 This article mentions the following:

A diversified ansa-ruthenium(II) catalyst series displaying enantiopure N,C-(N-alkylene-N-methylsulfamoyl)-tethered (DPEN-κ²N,N’)/η⁶-arene (DPEN = trans-1,2-diphenylethylenediamine) hybrid ligands was screened in the transfer hydrogenation of alkyl aryl ketones and α- or β-diketones in formic acid-triethylamine (HCO₂H-Et₃N) medium under mild conditions and furnished the alcs. in high to excellent ees. In the experiment, the researchers used many compounds, for example, (S)-1-(2-Fluorophenyl)ethanol (cas: 171032-87-4Application of 171032-87-4).

(S)-1-(2-Fluorophenyl)ethanol (cas: 171032-87-4) belongs to alcohols. A strong base can deprotonate an alcohol to yield an alkoxide ion (R―O−). For example, sodamide (NaNH2), a very strong base, abstracts the hydrogen atom of an alcohol. Tertiary alcohols cannot be oxidized at all without breaking carbon-carbon bonds, whereas primary alcohols can be oxidized to aldehydes or further oxidized to carboxylic acids.Application of 171032-87-4

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Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts