Tag: 100-200

Application In Synthesis of 3,7-Dimethyloctan-3-ol《Iron-catalyzed borylation and silylation of unactivated tertiary, secondary, and primary alkyl chlorides》 was published in 2021. The authors were Wang, Siyu;Sun, Minghui;Zhang, Huan;Zhang, Juan;He, Yun;Feng, Zhang, and the article was included in《CCS Chemistry》. The author mentioned the following in the article:

Herein, we describe an iron-catalyzed borylation and silylation of unactivated alkyl chlorides, delivering the tertiary, secondary, and primary alkylboronic esters, and secondary, primary alkylsilanes with high efficiency. This protocol exhibits broad substrate scope and good functional group compatibility, allowing the efficient late-stage borylation of biorelevant compounds, thus offering an excellent platform in drug discovery and development. Preliminary mechanistic studies suggest that an alkyl radical was involved in this catalytic system. And 3,7-Dimethyloctan-3-ol (cas: 78-69-3) was used in the research process.

3,7-Dimethyloctan-3-ol(cas:78-69-3) is a fatty alcohol that is 3-octanol substituted by methyl groups at positions 3 and 7.Application In Synthesis of 3,7-Dimethyloctan-3-ol Metabolite observed in cancer metabolism. It has a role as a human metabolite.

Reference:
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Safety of 4-tert-Amylphenol《Synergistic maximization of the carbohydrate output and lignin processability by combinatorial pretreatment》 was published in 2017. The authors were Liu, Zhi-Hua;Olson, Michelle L.;Shinde, Somnath;Wang, Xin;Hao, Naijia;Yoo, Chang Geun;Bhagia, Samarthya;Dunlap, John R.;Pu, Yunqiao;Kao, Katy C.;Ragauskas, Arthur J.;Jin, Mingjie;Yuan, Joshua S., and the article was included in《Green Chemistry》. The author mentioned the following in the article:

Lignocellulosic biorefineries have gained much attention worldwide as a potential solution to the challenges of energy demand and global climate change. However, the industrial implementation of biorefineries has been hindered by low fermentable sugar yields and low lignin processability. Combinatorial pretreatments with a low holding temperature were investigated in an effort to synergistically improve the carbohydrate output and lignin processability from corn stover. Upon combinatorial pretreatment with 1% H₂SO₄ for 30 min followed by 1% NaOH for 60 min at 120 °C, glucan and xylan conversion increased by 11.2% and 8.3% resp. relative to single pretreatment. This combinational pretreatment removed the amorphous portion, disrupted the rigid structure, and increased the water holding capacity of corn stover, thus increasing the hydrolysis performance. With whole fractionation by combinatorial pretreatment, glucose and xylose yields were 88.4% and 72.6%, resp., representing increases of 10.0% and 8.1%. The lignin yield was 19.7% in the solid residue and 77.6% in the liquid stream, which increased by 33.4%. When grown in fed-batch fermentation mode, a record level of polyhydroxyalkanoate (PHA) concentration (1.0 g l^-1) was obtained using lignin as a carbon source by Pseudomonas putida KT2440. Lignin characterization results showed that combinatorial pretreatment increased the G- and H-lignin content, reduced the β-β and β-O-4 groups, and fractionated more aromatic monomers, thus facilitating lignin processability into PHA. These results highlighted the use of combinational pretreatment at a low holding temperature as a means to synergistically maximize the carbohydrate output and lignin processability, which provides a unique set of features to improve the biorefining performance. The experimental procedure involved many compounds, such as 4-tert-Amylphenol (cas: 80-46-6) .

4-tert-acylphenol (cas:80-46-6) contains hydroxyl group. Owing to the presence of the polar OH alcohols are more water-soluble than simple hydrocarbons. Methanol, ethanol, and propanol are miscible in water. Butanol, with a four-carbon chain, is moderately soluble.Safety of 4-tert-Amylphenol

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Hamow, Kamiran Aron;Ambrozy, Zsuzsanna;Puskas, Katalin;Majlath, Imre;Cseplo, Monika;Matyus, Reka;Posta, Katalin;Lukacs, Peter;Sagi, Laszlo published 《Emission of novel volatile biomarkers for wheat powdery mildew》 in 2021. The article was appeared in 《Science of the Total Environment》. They have made some progress in their research.Recommanded Product: 3,7-Dimethyloctan-3-ol The article mentions the following:

Natural ecosystems including host-pathogen interactions produce a plethora of biogenic volatile organic compounds (BVOCs). Infections by phytopathogens change the volatile profile substantially and dynamically over a crop field or even on a larger scale. Despite their worldwide importance in agriculture little is known about the BVOC emissions of cereal crops, such as wheat, and their pathogens. The wheat-powdery mildew interaction is especially relevant, because powdery mildew is widespread on a global scale and is caused by an obligatory biotrophic pathogen (Blumeria graminis f.sp. tritici, Bgt). Since the BVOCs in this important fungus have still not been identified, the most frequent local natural pathotypes were studied by artificial inoculation and dynamic headspace collection followed by GC-MS anal. in three consecutive years. Of the 48 BVOCs identified in a total of 120 samples, six compounds (1,3-octadiene, 1,3-cis,5-cis-octatriene, 1-heptanol, (5Z)-octa-1,5-dien-3-ol, 1-octen-3-ol and 3-octanone) were detected only in Bgt-inoculated plants, and were hence quantitated. The latter three BVOCs were the most abundant in symptomatic plants with a characteristic distribution pattern. Addnl. wheat genotypes, different host plant development stages, and early and full disease progression in the presence of other pathogen mixes were also tested for the specificity of the proposed biomarkers. The three major biomarkers, namely (5Z)-octa-1,5-dien-3-ol, 1-octen-3-ol and 3-octanone were robustly applicable for differentiating the headspaces of healthy and mildew-infected plants even at early stages when disease symptoms are barely visible. These novel powdery mildew-related biomarkers are promising candidates for chemotyping and environmental monitoring in the field.3,7-Dimethyloctan-3-ol (cas: 78-69-3) were involved in the experimental procedure.

3,7-Dimethyloctan-3-ol(cas:78-69-3) is a fatty alcohol that is 3-octanol substituted by methyl groups at positions 3 and 7.Recommanded Product: 3,7-Dimethyloctan-3-ol Metabolite observed in cancer metabolism. It has a role as a human metabolite.

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Category: alcohols-buliding-blocksIn 2011, Pan, Xingang;Jia, Liangbin;Liu, Xuejian;Ma, Haikuo;Yang, Wenqian;Schwarz, Jacob B. published 《A general asymmetric synthesis of phenylglycinols》. 《Tetrahedron: Asymmetry》published the findings. The article contains the following contents:

Hydride reduction and deprotection of siloxymethyl sulfinimines, e.g., I, reliably furnished chiral phenylglycinols, e.g., II or III, in high overall yield and enantiomeric purity. The experimental procedure involved many compounds, such as (S)-2-Amino-2-(4-fluorophenyl)ethanol (cas: 224434-01-9) .

(S) – 2-amino-2 – (4-fluorophenyl) ethanol (cas: 224434-01-9) has the characteristics of alcohol. In general, the hydroxyl group makes alcohols polar. Those groups can form hydrogen bonds to one another and to most other compounds. Category: alcohols-buliding-blocks

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Related Products of 80-46-6In 2015, Di Nicola, Giovanni;Pierantozzi, Mariano published 《Surface tension of alcohols: A scaled equation and an artificial neural network》. 《Fluid Phase Equilibria》published the findings. The article contains the following contents:

This work presents a new formula to calculate the surface tension of alcs.As a first step, an anal. of the data available on the surface tension of alcs. was made. A total of 2121 data were collected for n-alcs., aromatic alcs., cycloaliphatic alcs., 2-alkanols and Me alkanols. The data were then regressed with the most reliable semi-empirical correlation methods in the literature based on the corresponding states theory. The scaled equation proposed is very simple and gives noticeable improvement with respect to existing equations.The same phys. parameters considered in the scaled equation were also adopted as input parameters in a multi-layer perceptron neural network, to predict the surface tension of alcs. The multilayer perceptron proposed has one hidden layer with 29 neurons, determined according to the constructive approach. The model developed was trained, validated and tested for the set of data collected, showing that the accuracy of the neural network model is very good. And 4-tert-Amylphenol (cas: 80-46-6) was used in the research process.

4-tert-acylphenol (cas:80-46-6) contains hydroxyl group. Owing to the presence of the polar OH alcohols are more water-soluble than simple hydrocarbons. Methanol, ethanol, and propanol are miscible in water. Butanol, with a four-carbon chain, is moderately soluble.Related Products of 80-46-6

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Alcohol – Wikipedia,
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SDS of cas: 78-69-3《Changes of amygdalin and volatile components of apricot kernels during the ultrasonically-accelerated debitterizing》 was published in 2019. The authors were Zhang, Ning;Zhang, Qing-An;Yao, Jian-Li;Zhang, Xin-Yun, and the article was included in《Ultrasonics Sonochemistry》. The author mentioned the following in the article:

Ultrasound has been regarded as an efficient novel technique for debitterizing of the apricot kernels, but its influence is severely concerned on the possible epimerization of D-amygdalin to the L-amygdalin, a more potentially toxigenic compound Considering this, the experiments were conducted to investigate the epimerization of D-amygdalin and the volatile components in the debitterizing water, which were separated and identified by the high performance liquid chromatog. (HPLC) and gas chromatog. with a mass spectrometer (GC-MS), resp. The results indicate that the ultrasonically-debitterizing did not cause the epimerization of D-amygdalin to the L-amygdalin, while the procedure can be greatly accelerated due to the rapid mass transfer and degradation of D-amygdalin induced by ultrasound irradiation In addition, the water from the ultrasonically-debitterizing of apricot kernels exerted more aromas compared with that of the conventional debitterizing, which might have more applications about this kind of water. In a word, ultrasound can be safely applied in the debitterizing industry of apricot kernels. To complete the study, the researchers used 3,7-Dimethyloctan-3-ol (cas: 78-69-3) .

3,7-Dimethyloctan-3-ol(cas:78-69-3) is a fatty alcohol that is 3-octanol substituted by methyl groups at positions 3 and 7.SDS of cas: 78-69-3 Metabolite observed in cancer metabolism. It has a role as a human metabolite.

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Alcohol – Wikipedia,
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HPLC of Formula: 78-69-3In 2017, Giovanelli, Silvia;Giusti, Giulia;Cioni, Pier Luigi;Minissale, Pietro;Ciccarelli, Daniela;Pistelli, Luisa published 《Aroma profile and essential oil composition of Rhus coriaria fruits from four Sicilian sites of collection》. 《Industrial Crops and Products》published the findings. The article contains the following contents:

The volatile fractions and essential oils from Rhus coriaria fruits collected in four locations in Sicily (Italy) were characterized by GC-FID and GC-MS anal. Monoterpenes were identified as the main class of constituents in volatiles spontaneously emitted by sumac fruits collected in two of the four sites (42.1-59.9% in ‘CNS’ and ‘CIN’ resp.), while non terpenic compounds predominated in the other two (46.1-52.8% in ‘MR’ and ‘CG’, resp.). The EO composition were characterized by high amount of non terpenic compounds (from 27.5 to 55.1%), followed by sesquiterpenes and diterpenes. p-anisaldehyde was the main constituent both in volatiles emitted by ‘CG’ sample and in its essential oil (28.4 and 20.8%, resp.). The comparison between the EOs obtained from the Sicilian samples differed from the EO obtained from sumac fruits purchased on the Jordanian market, even though a similar composition were evidenced with Turkish samples reported in the literature. And 3,7-Dimethyloctan-3-ol (cas: 78-69-3) was used in the research process.

3,7-Dimethyloctan-3-ol(cas:78-69-3) is a fatty alcohol that is 3-octanol substituted by methyl groups at positions 3 and 7.HPLC of Formula: 78-69-3 Metabolite observed in cancer metabolism. It has a role as a human metabolite.

Reference:
Alcohol – Wikipedia,
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SDS of cas: 148-51-6《Synthesis of vitamin B₆ derivatives. Catalytic reduction of hydroxymethyl group substituted in pyridine ring》 was published in 1959. The authors were Naito, Takeo;Ueno, Katsujiro, and the article was included in《Yakugaku Zasshi》. The author mentioned the following in the article:

Catalytic reduction of 1.64 g. pyridoxine triacetate-HCl in 32 mL. H₂O with 1 g. 10% Pd-C 1.5 h. at normal pressure of H absorbed 240 mL. H and gave 0.7 g. 3,4,6,5-Me₃(OH)C₅HN.HCl (I), m. 209-12°. Similarly, pyridoxine 4-Et ether HCl salt yielded 52% I, m. 210-12°. The above reaction with 1 mol absorption of H yielded 18% 4,6,3,5-Me₂(HOCH₂)(HO)C₅HN.HCl (II), m. 250° (decomposition), and the mother liquor yielded 31% 3,6,4,5-Me₂(EtOCH₂)(HO)C₅HN.HCl; picrate m. 138°. Catalytic reduction of 0.56 g. 6,3,4,5-Me(AcOCH₂)(EtOCH₂)(HO)C₅HN.HCl in 20 mL. MeOH with 0.8 g. 10% Pd-C showed no absorption of H, the reduction proceeded well by addition of 20 mL. H₂O and absorbed 54 mL. H in 2 h., and the product in 10% HCl heated 30 min. at 100° yielded 48.8% 3,6,4,5-Me₂(EtOCH₂)(HO)C₅HN; picrate, m. 138°. Catalytic reduction of 3.76 g. pyridoxal oxime-HCl in 170 mL. H₂O and 88 mL. 10% HCl with 4.8 g. 10% Pd-C absorbed 3050 mL. H in 20 h. and yielded 62% 3,6,4,5-Me₂(HCl.H₂NCH₂)(HO)C₅HN.HCl (III), m. 262-3° (decomposition); diacetate, C₁₂H₁₆O₃N₂, m. 176-7°; ditosylate-HCl, m. 194-5°. Catalytic reduction of 0.29 g. 6,3,4,5-Me(AcOCH₂)(AcNHCH₂)(AcO)C₅HN in 8 mL. MeOH and 2.2 mL. 10% HCl-MeOH showed no absorption H but an addition of 10 mL. H₂O absorbed 28 mL. H in 2 h. and yielded 100% diacetate of III, m. 174°. Similarly, 0.51 g. pyridoxal-HCl in 20 mL. H₂O and 0.5 g. 10% Pd-C yielded 30% II, m. 246-8°. Catalytic reduction of 0.58 g. pyridoxal Et hemiacetal-HCl (IV) in 20 mL. EtOH and 0.5 g. 10% Pd-C (1 mol H absorbed) yielded 79% 6,5,3,4-Me(HO)(CH₂OCH₂)C₅HN.HCl (V), m. 233-4°; picrate m. 186-7°. Similarly, 0.58 g. IV, 20 mL. H₂O and 0.5 g. Pd-C yielded 40% II, m. 248-50°; 0.58 g. IV, 20 mL. HCl, 2.7 mL. 10% HCl and 0.5 g. Pd-C yielded 68% V, m. 225-30°. Catalytic reduction of 1.09 g. 2-HOCH₂C₅H₄ N in 15 mL. MeOH and 51 mL. 5% HCl-MeOH with 1 g. Pd-C (260 mL. H absorbed in 2 h.) yielded 90% 2-MeC₅H₄N (VI); picrate m. 164-5°. Similarly, 1.23 g. 2-MeOCH₂C₅H₄N in 15 mL. MeOH and 51 mL. 5% HCl-MeOH with 0.1 g. Pd-C (255 mL. H absorbed) yielded 91% 2-MeC₅H₄N; or, 2-AcOCH₂C₅H₄N, in a similar way, yielded 88% 2-MeC₅H₄N. 2-HOCH₂C₅H₄N.HCl (8 g.) added dropwise into 40 g. SOCl₂ with cooling, refluxed 2 h., cooled, 100 mL. C₆H₆ added and the product filtered off gave 8.8 g. 2-ClCH₂C₅H₄N (VII); picrate m. 146-7°. MeONa (2.72 g. Na and 55 mL. MeOH) treated dropwise with VII in 20 mL. MeOH, refluxed 1 h., the solvent removed and the residue extracted with Et₂O gave 4.7 g. 2-MeOCH₂C₅H₄N, b₁₈ 76-8°. Similarly are prepared (product, b.p./mm. and m.p. picrate given): 3-MeOCH₂C₅H₄N, 92-4°/20, 117-18°; 4-MeOCH₂C₅H₄N, 91-2°/19, 108-9°. To complete the study, the researchers used 5-(hydroxymethyl)-2,4-dimethylpyridin-3-ol hydrochloride (cas: 148-51-6) .

5-(hydroxymethyl)-2,4-dimethylpyridin-3-ol hydrochloride(cas:148-51-6 SDS of cas: 148-51-6) is a vitamin B6 antimetabolite with diverse biological activities. It inhibits transport of pyridoxine , pyridoxal, and pyridoxamine in and reduces growth of S. carlsbergensis cells. DOP inhibits sphingosine-1-phosphate (S1P) lyase and reduces cyclic stretch-induced apoptosis in alveolar epithelial MLE-12 cells.

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dos Santos Andrade, Moacir;do Prado Ribeiro, Leandro;Borgoni, Paulo Cesar;das Gracas Fernandes da Silva, Maria Fatima;Forim, Moacir Rossi;Fernandes, Joao Batista;Vieira, Paulo Cezar;Vendramin, Jose Djair;Machado, Marcos Antonio published 《Essential oil variation from twenty two genotypes of Citrus in Brazil-chemometric approach and repellency against Diaphorina citri Kuwayama》. The research results were published in《Molecules》 in 2016.COA of Formula: C10H22O The article conveys some information:

The chem. composition of volatile oils from 22 genotypes of Citrus and related genera was poorly differentiated, but chemometric techniques have clarified the relationships between the 22 genotypes, and allowed us to understand their resistance to D. citri. The most convincing similarities include the synthesis of (Z)-β-ocimene and (E)-caryophyllene for all 11 genotypes of group A. Genotypes of group B are not uniformly characterized by essential oil compounds When stimulated with odor sources of 22 genotypes in a Y-tube olfactometer D. citri preferentially entered the arm containing the volatile oils of Murraya paniculata, confirming orange jasmine as its best host. C. reticulata × C. sinensis was the least preferred genotype, and is characterized by the presence of phytol, (Z)-β-ocimene, and β-elemene, which were not found in the most preferred genotype. We speculate that these three compounds may act as a repellent, making these oils less attractive to D. citri. The experimental procedure involved many compounds, such as 3,7-Dimethyloctan-3-ol (cas: 78-69-3) .

3,7-Dimethyloctan-3-ol(cas:78-69-3) is a fatty alcohol that is 3-octanol substituted by methyl groups at positions 3 and 7.COA of Formula: C10H22O Metabolite observed in cancer metabolism. It has a role as a human metabolite.

Reference:
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Related Products of 224434-01-9《Chiral Alkyl Amine Synthesis via Catalytic Enantioselective Hydroalkylation of Enecarbamates》 was published in 2021. The authors were Qian, Deyun;Bera, Srikrishna;Hu, Xile, and the article was included in《Journal of the American Chemical Society》. The author mentioned the following in the article:

A nickel-catalyzed hydroalkylation method to assemble a wide range of chiral alkyl amines from enecarbamates (N-Cbz-protected enamines) and alkyl halides with high regio- and enantioselectivity was reported. The method works for both nonactivated and activated alkyl halides and was able to produce enantiomerically enriched amines with two minimally differentiated α-alkyl substituents. The mild conditions led to high functional group tolerance, which is demonstrated in the postproduct functionalization of many natural products and drug mols., as well as the synthesis of chiral building blocks and key intermediates to bioactive compounds And (S)-2-Amino-2-(4-fluorophenyl)ethanol (cas: 224434-01-9) was used in the research process.

(S) – 2-amino-2 – (4-fluorophenyl) ethanol (cas: 224434-01-9) has the characteristics of alcohol. In general, the hydroxyl group makes alcohols polar. Those groups can form hydrogen bonds to one another and to most other compounds. Related Products of 224434-01-9

Reference:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts