Tag: 0-100

Soil VOC emissions of a Mediterranean woodland are sensitive to shrub invasion was written by Meischner, M.;Haberstroh, S.;Daber, L. E.;Kreuzwieser, J.;Caldeira, M. C.;Schnitzler, J.-P.;Werner, C.. And the article was included in Plant Biology (Berlin, Germany) in 2022.Related Products of 57-55-6 This article mentions the following:

Many belowground processes, such as soil respiration and soil-atm. VOC (volatile organic compounds) exchange, are closely linked to soil microbiol. processes. However, little is known about how changes in plant species cover, i.e. after plant invasion, alter these soil processes. In particular, the response of soil VOC emissions to plant invasion is not well understood. We analyzed soil VOC emissions and soil respiration of a Mediterranean cork oak (Quercus suber) ecosystem, comparing soil VOC emissions from a non-invaded Q. suber woodland to one invaded by the shrub Cistus ladanifer. Soil VOC emissions were determined under controlled conditions using online proton-transfer time-of-flight mass spectrometry. Net soil VOC emissions were measured by exposing soils with or without litter to different temperature and soil moisture conditions. Soil VOC emissions were sensitive to C. ladanifer invasion. Highest net emission rates were determined for oxygenated VOC (acetaldehyde, acetone, methanol, acetic acid), and high temperatures enhanced total VOC emissions. Invasion affected the relative contribution of various VOC. Methanol and acetaldehyde were emitted exclusively from litter and were associated with the non-invaded sites. In contrast, acetone emissions increased in response to shrub presence. Interestingly, low soil moisture enhanced the effect of shrub invasion on VOC emissions. Our results indicate that shrub invasion substantially influences important belowground processes in cork oak ecosystems, in particular soil VOC emissions. High soil moisture is suggested to diminish the invasion effect through a moisture-induced increase in microbial decomposition rates of soil VOC. In the experiment, the researchers used many compounds, for example, 1,2-Propanediol (cas: 57-55-6Related Products of 57-55-6).

1,2-Propanediol (cas: 57-55-6) belongs to alcohols. A strong base can deprotonate an alcohol to yield an alkoxide ion (R―O−). For example, sodamide (NaNH2), a very strong base, abstracts the hydrogen atom of an alcohol. The most common reactions of alcohols can be classified as oxidation, dehydration, substitution, esterification, and reactions of alkoxides.Related Products of 57-55-6

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Depolymerizable Poly(O-vinyl carbamate-alt-sulfones) as Customizable Macromolecular Scaffolds for Mucosal Drug Delivery was written by Kumar, Kaushlendra;Castano, Eduard Jimenez;Weidner, Andrew R.;Yildirim, Adem;Goodwin, Andrew P.. And the article was included in ACS Macro Letters in 2016.Recommanded Product: (R)-2-Aminobutan-1-ol This article mentions the following:

Interest in stimulus responsive materials and polymers has grown over the years, having shown great promise in a diverse set of applications. For drug delivery, stimulus-responsive polymers have been shown to encapsulate therapeutics such as small mol. drugs or proteins, deliver them to specific locations in the body, and release them so that they can induce a therapeutic effect in the patient. Most hydrolytically degradable polymers are synthesized via nucleophilic, anionic, or cationic polymerization, which generally requires protection of nucleophilic or protic side chains prior to polymerization Here, we report the synthesis of novel, alternating copolymers of sulfur dioxide and O-vinyl carbamate monomers that boast excellent functional group tolerance and pH-dependent instability. Alternating copolymers were synthesized containing pendant functionalities such as alc., carboxylic acid, ester, and azide without deprotection or postpolymn. modification. The copolymers were then formulated via nanopptn. into polymer nanoparticles capable of encapsulating small mol. dyes. The polymer nanoparticles were found to degrade rapidly at pH > 6 but were stable even in highly acidic conditions. Based on this observation, a proof-of-concept study for mucosal delivery was performed using polymer nanoparticles entrapped in a mucus model. At pH 8, the diffusion of encapsulated dye was found to be similar to free dye, while at pH 5 the diffusion coefficient was an order of magnitude lower. Cell viability was retained at 200 μg/mL particles after 24 h incubation. These polymers thus show promise as customizable scaffolds for mucosal drug delivery. In the experiment, the researchers used many compounds, for example, (R)-2-Aminobutan-1-ol (cas: 5856-63-3Recommanded Product: (R)-2-Aminobutan-1-ol).

(R)-2-Aminobutan-1-ol (cas: 5856-63-3) belongs to alcohols. The oxygen atom of the strongly polarized O―H bond of an alcohol pulls electron density away from the hydrogen atom. This polarized hydrogen, which bears a partial positive charge, can form a hydrogen bond with a pair of nonbonding electrons on another oxygen atom. Tertiary alcohols cannot be oxidized at all without breaking carbon-carbon bonds, whereas primary alcohols can be oxidized to aldehydes or further oxidized to carboxylic acids.Recommanded Product: (R)-2-Aminobutan-1-ol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Several human cyclin-dependent kinase inhibitors, structurally related to roscovitine, as new anti-malarial agents was written by Houze, Sandrine;Hoang, Nha-Thu;Lozach, Olivier;Le Bras, Jacques;Meijer, Laurent;Galons, Herve;Demange, Luc. And the article was included in Molecules in 2014.Recommanded Product: (R)-2-Aminobutan-1-ol This article mentions the following:

In Africa, malaria kills one child each minute. It is also responsible for about one million deaths worldwide each year. Plasmodium falciparum, is the protozoan responsible for the most lethal form of the disease, with resistance developing against the available anti-malarial drugs. Among newly proposed anti-malaria targets, are the P. falciparum cyclin-dependent kinases (PfCDKs). There are involved in different stages of the protozoan growth and development but share high sequence homol. with human cyclin-dependent kinases (CDKs). We previously reported the synthesis of CDKs inhibitors that are structurally-related to (R)-roscovitine, a 2,6,9-trisubstituted purine, and they showed activity against neuronal diseases and cancers. In this report, we describe the synthesis and the characterization of new CDK inhibitors, active in reducing the in vitro growth of P. falciparum (3D7 and 7G8 strains). Six compounds are more potent inhibitors than roscovitine, and three exhibited IC50 values close to 1 μM for both 3D7 and 7G8 strains. Although, such mols. do inhibit P. falciparum growth, they require further studies to improve their selectivity for PfCDKs. In the experiment, the researchers used many compounds, for example, (R)-2-Aminobutan-1-ol (cas: 5856-63-3Recommanded Product: (R)-2-Aminobutan-1-ol).

(R)-2-Aminobutan-1-ol (cas: 5856-63-3) belongs to alcohols. Similar to water, an alcohol can be pictured as having an sp3 hybridized tetrahedral oxygen atom with nonbonding pairs of electrons occupying two of the four sp3 hybrid orbitals. Grignard and organolithium reagents are powerful tools for organic synthesis, and the most common products of their reactions are alcohols.Recommanded Product: (R)-2-Aminobutan-1-ol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Cu(II), Ni(II) complexes derived from chiral Schiff-base ligands: Synthesis, characterization, cytotoxicity, protein and DNA-binding properties was written by Li, Zhen;Yan, Hui;Chang, Guoliang;Hong, Min;Dou, Jianmin;Niu, Meiju. And the article was included in Journal of Photochemistry and Photobiology, B: Biology in 2016.Recommanded Product: (R)-2-Aminobutan-1-ol This article mentions the following:

A series of novel copper(II) and nickel(II) complexes derived from chiral Schiff-base ligands [(R)/(S)-H₂L¹ = (R)/(S)-2-[(1-Hydroxymethyl-propylimino)-methyl]-5-methoxy-phenol and (R)/(S)-H₂L² = (R)/(S)-2-[(1-Hydroxymethyl-2-phenyl-ethylimino)-methyl]-5-methoxy-phenol], were synthesized and characterized by elemental analyses, ¹H NMR spectra, FTIR spectrum. The crystal structures of 1–5 [Ni₂L₂(OAc)₂(solv)₂] were determined through single crystal x-ray diffraction (SXRD). The structures showed the ligands coordinated to the Cu/Ni(II) ion in a neutral manner via ONO donor atoms, and oxygen atoms of solvent mols. occupy the axial positions in Ni(II) complexes 3 and 4. The complexes interactions with BSA and CT-DNA were investigated by various spectroscopic methods (UV-Visible, CD spectrum, fluorescence spectroscopic and synchronous fluorescence spectra). Interactions of chiral copper(II) complexes are stronger than nickel(II) complexes. Further, the cytotoxicities of 1–6 towards three kinds of cancerous cell lines, were human lung adenocarcinoma (A549), human cervical carcinoma cell (HeLa) and human breast cancer cell (MCF-7), resp., were evaluated by MTT assay. All complexes exhibited good cytotoxic activity. Furthermore, Cu(II) complex 5 derived from (R)-Schiff-base ligand is more effective towards HeLa cancerous cell. Chirality and metal ion have important influence on their anticancer activities and interactions with DNA/BSA. In the experiment, the researchers used many compounds, for example, (R)-2-Aminobutan-1-ol (cas: 5856-63-3Recommanded Product: (R)-2-Aminobutan-1-ol).

(R)-2-Aminobutan-1-ol (cas: 5856-63-3) belongs to alcohols. Because alcohols are easily synthesized and easily transformed into other compounds, they serve as important intermediates in organic synthesis. Under carefully controlled conditions, simple alcohols can undergo intermolecular dehydration to give ethers. This reaction is effective only with methanol, ethanol, and other simple primary alcohols.Recommanded Product: (R)-2-Aminobutan-1-ol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Highly regioselective tandem hydroformylation of substituted styrene using Iminophosphine rhodium complex immobilized on carbon was written by Singh, Amravati S.;Jindani, Sana;Ganguly, Bishwajit;Biradar, Ankush V.. And the article was included in Journal of Industrial and Engineering Chemistry (Amsterdam, Netherlands) in 2022.Recommanded Product: 1,2-Propanediol This article mentions the following:

Reported the sustainable route for the synthesis of ionic carbon from bio-derived sugarcane-waste (Bagasse) and further anchoring with iminophosphine rhodium complex (Rh@BCNP) and utilized for tandem hydroformylation reaction. The SEM anal. confirmed the formation of spherical shape morphol. of carbon with sizes ranging from 30-150 nm. The successful functionalization of the iminophosphine rhodium complex on the carbon surface were determined by XPS, TEM, FE-SEM, ³¹P NMR, ¹³C CP-MAS-NMR and FTIR anal. Furthermore, ICP-OES anal. confirmed the presence of 0.307 mmoles/g of Rh and 0.484 mmoles/g of P on the carbon surface. Rh@BCNP catalyst was the best combination of triphenylphosphine ligand, imine and rhodium metal, resulting in hybrid material with some acidic properties of carbon that favor the selectivity towards linear products. Rh@BCNP showed remarkable catalytic performance under moderate reaction conditions (80°C, 40 bar (CO + H₂)) in 5 h. This sharp divergence from other methods leading to linear amines and acetals results in a novel atom economic approach to synthesize pharmaceuticals and industrial products. The Rh@BCNP catalyst gave recyclability up to five cycles. In the experiment, the researchers used many compounds, for example, 1,2-Propanediol (cas: 57-55-6Recommanded Product: 1,2-Propanediol).

1,2-Propanediol (cas: 57-55-6) belongs to alcohols. The oxygen atom of the strongly polarized O―H bond of an alcohol pulls electron density away from the hydrogen atom. This polarized hydrogen, which bears a partial positive charge, can form a hydrogen bond with a pair of nonbonding electrons on another oxygen atom. The most common reactions of alcohols can be classified as oxidation, dehydration, substitution, esterification, and reactions of alkoxides.Recommanded Product: 1,2-Propanediol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Biogenesis of a bacterial metabolosome for propanediol utilization was written by Yang, Mengru;Wenner, Nicolas;Dykes, Gregory F.;Li, Yan;Zhu, Xiaojun;Sun, Yaqi;Huang, Fang;Hinton, Jay C. D.;Liu, Lu-Ning. And the article was included in Nature Communications in 2022.Related Products of 57-55-6 This article mentions the following:

Bacterial metabolosomes are a family of protein organelles in bacteria. Elucidating how thousands of proteins self-assemble to form functional metabolosomes is essential for understanding their significance in cellular metabolism and pathogenesis. Here we investigate the de novo biogenesis of propanediol-utilization (Pdu) metabolosomes and characterize the roles of the key constituents in generation and intracellular positioning of functional metabolosomes. Our results demonstrate that the Pdu metabolosome undertakes both “Shell first” and “Cargo first” assembly pathways, unlike the β-carboxysome structural analog which only involves the “Cargo first” strategy. Shell and cargo assemblies occur independently at the cell poles. The internal cargo core is formed through the ordered assembly of multiple enzyme complexes, and exhibits liquid-like properties within the metabolosome architecture. Our findings provide mechanistic insight into the mol. principles driving bacterial metabolosome assembly and expand our understanding of liquid-like organelle biogenesis. In the experiment, the researchers used many compounds, for example, 1,2-Propanediol (cas: 57-55-6Related Products of 57-55-6).

1,2-Propanediol (cas: 57-55-6) belongs to alcohols. Similar to water, an alcohol can be pictured as having an sp3 hybridized tetrahedral oxygen atom with nonbonding pairs of electrons occupying two of the four sp3 hybrid orbitals. Tertiary alcohols cannot be oxidized at all without breaking carbon-carbon bonds, whereas primary alcohols can be oxidized to aldehydes or further oxidized to carboxylic acids.Related Products of 57-55-6

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Stereodynamic Chemosensor with Selective Circular Dichroism and Fluorescence Readout for in Situ Determination of Absolute Configuration, Enantiomeric Excess, and Concentration of Chiral Compounds was written by Bentley, Keith W.;Wolf, Christian. And the article was included in Journal of the American Chemical Society in 2013.Formula: C4H11NO This article mentions the following:

A stereodynamic chemosensor, 1-(4′-pyridyl)-8-(3′-formyl-4′-hydroxyphenyl)naphthalene N-oxide, having a parallel arrangement of a substrate-binding salicylaldehyde unit and an adjacent pyridyl N-oxide fluorophore undergoes rapid condensation with chiral amino alcs. and subsequent asym. transformation of the 1st kind toward a single rotamer. Crystallog. anal. shows that the concomitant central-to-axial chirality imprinting is controlled by minimization of steric repulsion and by intramol. hydrogen bonding between the bound amino alc. and the proximate N-oxide group. The substrate binding event results in strong CD effects and characteristic fluorescence changes which can be used for instantaneous in situ determination of the absolute configuration, enantiomeric composition and total concentration of a variety of chiral amino alcs. This chemosensing approach avoids time-consuming workup and purification steps, and it is applicable to minute sample amounts which reduces the use of solvents and limits waste production In the experiment, the researchers used many compounds, for example, (R)-2-Aminobutan-1-ol (cas: 5856-63-3Formula: C4H11NO).

(R)-2-Aminobutan-1-ol (cas: 5856-63-3) belongs to alcohols. Under appropriate conditions, inorganic acids also react with alcohols to form esters. To form these esters, a wide variety of specialized reagents and conditions can be used. Alcohols may be oxidized to give ketones, aldehydes, and carboxylic acids. These functional groups are useful for further reactions. Oxidation of organic compounds generally increases the number of bonds from carbon to oxygen (or another electronegative element, such as a halogen), and it may decrease the number of bonds to hydrogen.Formula: C4H11NO

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Non-covalent interactions of selected flavors with pea protein: Role of molecular structure of flavor compounds was written by Bi, Shuang;Pan, Xin;Zhang, Wentao;Ma, Zhuo;Lao, Fei;Shen, Qun;Wu, Jihong. And the article was included in Food Chemistry in 2022.Reference of 57-55-6 This article mentions the following:

The influence of the mol. structures of flavor compounds (specifically, variations in chain length and functional groups) on the binding of the flavor compounds (Z)-2-penten-1-ol, hexanal, and (E)-2-octenal to pea protein was investigated. The results showed that the mol. structures of the flavor compounds strongly influenced their binding affinity for pea protein. Specifically, (E)-2-octenal exhibited a higher binding affinity and a higher Stern-Volmer constant with pea protein than both hexanal and (Z)-2-penten-1-ol. Thermodn. anal. indicated that the flavor compound-pea protein interactions were spontaneous. Hydrophobic interactions were dominant in the non-covalent interactions between (E)-2-octenal/(Z)-2-penten-1-ol and pea protein, whereas hydrogen bonding was dominant in the non-covalent interactions between hexanal and pea protein. Surface hydrophobicity measurements, the use of bond-disrupting agents, and mol. docking further supported the hypothesis that hydrogen bonding, as well as hydrophobic interactions, occurred between the flavor compounds and pea protein. In the experiment, the researchers used many compounds, for example, 1,2-Propanediol (cas: 57-55-6Reference of 57-55-6).

1,2-Propanediol (cas: 57-55-6) belongs to alcohols. A strong base can deprotonate an alcohol to yield an alkoxide ion (R―O−). For example, sodamide (NaNH2), a very strong base, abstracts the hydrogen atom of an alcohol. Under carefully controlled conditions, simple alcohols can undergo intermolecular dehydration to give ethers. This reaction is effective only with methanol, ethanol, and other simple primary alcohols.Reference of 57-55-6

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Bifunctional Metal-free Heterogeneous Catalyst for the Synthesis of Methanol and Diols from CO₂ and Epoxide was written by Chatterjee, Rupak;Bhattacharjee, Sudip;Bhaumik, Asim. And the article was included in Asian Journal of Organic Chemistry in 2022.Product Details of 57-55-6 This article mentions the following:

Currently world is facing a serious environmental concern in the steady increase in the CO₂ concentration in air and this is directly related to climate change. Thus, successful utilization of CO₂ into valuable chems. is one of our primary goals. Herein, we have successfully fabricated a porous organic polymer PDVTA-1 via the free radical cross coupling between divinylbenzene and triallyl amine. This porous polymer is found to possess permanent porosity with a very high BET surface area of 915 m² g^-1. Furthermore, upon sulfonation PDVTA-1 is found to be very active as a bifunctional catalyst with a high BET surface area of 477 m²g^-1 and it efficiently catalyzes the synthesis of methanol and diols from CO₂ and resp. epoxide under solvent-free process and relatively milder reaction conditions. In this method 34% yield of methanol and 53% propylene glycol are produced from CO₂ and propylene oxide by using considerably mild reducing agent Et₃SiH. In the experiment, the researchers used many compounds, for example, 1,2-Propanediol (cas: 57-55-6Product Details of 57-55-6).

1,2-Propanediol (cas: 57-55-6) belongs to alcohols. A strong base can deprotonate an alcohol to yield an alkoxide ion (R―O−). For example, sodamide (NaNH2), a very strong base, abstracts the hydrogen atom of an alcohol. Alcohols may be oxidized to give ketones, aldehydes, and carboxylic acids. These functional groups are useful for further reactions. Oxidation of organic compounds generally increases the number of bonds from carbon to oxygen (or another electronegative element, such as a halogen), and it may decrease the number of bonds to hydrogen.Product Details of 57-55-6

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Effect of MgO addition to Cu-Ni/Al₂O₃ catalysts on glycerol hydrogenolysis in continuous reactor without external hydrogen was written by Mendonca, Victor G. S.;Freitas, Isabelle C.;Manfro, Robinson L.;Souza, Mariana M. V. M.. And the article was included in Applied Catalysis, A: General in 2022.Quality Control of 1,2-Propanediol This article mentions the following:

Cu-Ni/xMgO-Al₂O₃ catalysts with x = 0, 10, 20 and 30 wt% were prepared and evaluated in glycerol hydrogenolysis to 1,2-propanediol (1,2-PDO) at 250°C, pressure of 40 bar for 30 h, without addition of external hydrogen. The addition of MgO to alumina decreased the surface area, increased the Cu/Ni dispersion and the number of basic sites. The highest 1,2-PDO yield was achieved by Cu-Ni/30%MgO-Al₂O₃ catalyst: 50% after 6 h of reaction; it decreases to 25% after 30 h. The decrease in 1,2-PDO yield is accompanied by an increase in acetol yield, showing that the rate limiting step for MgO-Al₂O₃ catalysts is the hydrogenation of acetol to 1,2-PDO because there is not enough hydrogen in reaction medium. For Cu-Ni/MgO catalyst, the reaction pathway changed to the basic route, with preferential formation of lactic acid (50% of lactic acid yield in the first hours of reaction). In the experiment, the researchers used many compounds, for example, 1,2-Propanediol (cas: 57-55-6Quality Control of 1,2-Propanediol).

1,2-Propanediol (cas: 57-55-6) belongs to alcohols. Alcohols are weak acids. The most acidic simple alcohols (methanol and ethanol) are about as acidic as water, and most other alcohols are somewhat less acidic. Converting an alcohol to an alkene requires removal of the hydroxyl group and a hydrogen atom on the neighbouring carbon atom. Dehydrations are most commonly carried out by warming the alcohol in the presence of a strong dehydrating acid, such as concentrated sulfuric acid.Quality Control of 1,2-Propanediol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts