Tag: 0-100

Thermal conductivity performance in propylene glycol-based Darcy-Forchheimer nanofluid flow with entropy analysis was written by Wang, Fuzhang;Khan, Sohail A.;Khan, M. Ijaz;El-Zahar, Essam Roshdy;Yasir, M.;Nofal, Taher A.;Malik, M. Y.. And the article was included in Journal of Petroleum Science & Engineering in 2022.Quality Control of 1,2-Propanediol This article mentions the following:

Entropy generation is a novel prospective in many thermodn. processes and presents dynamic applications in heat polymer processing optimization. The significance of entropy generation is observed in heat exchangers, combustion, thermal systems, nuclear reactions, turbine systems, porous media and many others. In view of such thermal applications, the main objective of recent anal. is to analyze the entropy optimized anal. for dissipative flow of Darcy-Forchheimer nanofluid over a permeable medium. Flow is generated by stretching of surface. Thermal radiation and viscous dissipation are incorporated in heat expression. Boehmite (AlOOH) and silica (SiO₂) are considered as nanoparticles. Here propylene glycol (C₃H₈O₂) is considered as continuous phase fluid. Entropy features is discussed through thermodn. second law. Nonlinear ordinary dimensionless form is obtained through suitable dimensionless variables. The obtained dimensionless expressions are numerically solved by implementation of ND-solve method. Graphical feature of entropy rate, temperature, Bejan number and velocity profile against flow variables for both Boehmite (AlOOH) and silica (SiO₂) nanoparticles are discussed. Computational results of thermal transport rate and drag force vs. sundry variables for Boehmite and silica nanoparticles are studied. An increment in velocity profile is seen through volume fraction. In the experiment, the researchers used many compounds, for example, 1,2-Propanediol (cas: 57-55-6Quality Control of 1,2-Propanediol).

1,2-Propanediol (cas: 57-55-6) belongs to alcohols. A strong base can deprotonate an alcohol to yield an alkoxide ion (R―O−). For example, sodamide (NaNH2), a very strong base, abstracts the hydrogen atom of an alcohol. Under carefully controlled conditions, simple alcohols can undergo intermolecular dehydration to give ethers. This reaction is effective only with methanol, ethanol, and other simple primary alcohols.Quality Control of 1,2-Propanediol

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Design, Synthesis, and In Vitro and In Vivo Antifungal Activity of Novel Triazoles Containing Phenylethynyl Pyrazole Side Chains was written by Ni, Tingjunhong;Ding, Zichao;Xie, Fei;Hao, Yumeng;Bao, Junhe;Zhang, Jingxiang;Yu, Shichong;Jiang, Yuanying;Zhang, Dazhi. And the article was included in Molecules in 2022.Electric Literature of C4H11NO This article mentions the following:

A series of triazole derivatives containing phenylethynyl pyrazole moiety as side chain I (R = 4-fluorobenzylaminyl, 4-hydroxypiperidin-1-yl, morpholin-4-yl, etc.) and II (R¹ = F, Cl, CN, CF₃, OCF₃) were designed, synthesized, and most of them exhibited good in vitro antifungal activities. Especially, triazole derivatives I (R = (furan-2-ylmethyl)aminyl) and II (R¹ = CN) showed excellent in vitro activities against C. albicans (MIC = 0.125, 0.0625μg/mL), C. neoformans (MIC = 0.125, 0.0625μg/mL), and A. fumigatus (MIC = 8.0, 4.0μg/mL). Triazole derivatives II (R¹ = CN) also exerted superior activity to triazole derivatives I (R = (furan-2-ylmethyl)aminyl) and fluconazole in inhibiting hyphae growth of C. albicans and inhibiting drug-resistant strains of C. albicans, and it could reduce fungal burdens in mice kidney at a dosage of 1.0 mg/kg. An in vivo efficacy evaluation indicated that triazole derivatives II (R¹ = CN) could effectively protect mice models from C. albicans infection at doses of 0.5, 1.0, and 2.0 mg/kg. These results suggested that triazole derivatives II (R¹ = CN) deserves further investigation. In the experiment, the researchers used many compounds, for example, (R)-2-Aminobutan-1-ol (cas: 5856-63-3Electric Literature of C4H11NO).

(R)-2-Aminobutan-1-ol (cas: 5856-63-3) belongs to alcohols. Under appropriate conditions, inorganic acids also react with alcohols to form esters. To form these esters, a wide variety of specialized reagents and conditions can be used. A multistep synthesis may use Grignard-like reactions to form an alcohol with the desired carbon structure, followed by reactions to convert the hydroxyl group of the alcohol to the desired functionality.Electric Literature of C4H11NO

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Meta-selective C_Ar-H nitration of arenes through a Ru₃(CO)₁₂-catalyzed ortho-metalation strategy was written by Fan, Zhoulong;Ni, Jiabin;Zhang, Ao. And the article was included in Journal of the American Chemical Society in 2016.Synthetic Route of C4H11NO This article mentions the following:

The first example of transition metal-catalyzed meta-selective C_Ar-H nitration of arenes, substituted with N-donor directing groups, such as 2-phenylpyridines, is described. With the use of Ru₃(CO)₁₂ as the catalyst and Cu(NO₃)₂·3H₂O as the nitro source, a wide spectrum of arenes bearing diversified N-heterocycles or oximido as the directing groups were nitrated with meta-selectivity exclusively. Mechanism studies have demonstrated the formation of a new 18e-octahedral ruthenium species as a key ortho-C_Ar-H metalated intermediate, which may be responsible for the subsequent meta-selective electrophilic aromatic substitution (S_EAr). Moreover, this approach provides a fast-track strategy for atom/step economical synthesis of many useful pharmaceutical mols. In the experiment, the researchers used many compounds, for example, (R)-2-Aminobutan-1-ol (cas: 5856-63-3Synthetic Route of C4H11NO).

(R)-2-Aminobutan-1-ol (cas: 5856-63-3) belongs to alcohols. Because alcohols are easily synthesized and easily transformed into other compounds, they serve as important intermediates in organic synthesis. The most common reactions of alcohols can be classified as oxidation, dehydration, substitution, esterification, and reactions of alkoxides.Synthetic Route of C4H11NO

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Transition Metal-Free Synthesis of meta-Bromo- and meta-Trifluoromethylanilines from Cyclopentanones by a Cascade Reaction was written by Staudt, Markus;Cetin, Adnan;Bunch, Lennart. And the article was included in Chemistry – A European Journal in 2022.COA of Formula: C4H11NO This article mentions the following:

A transition metal-free method for the synthesis of meta-bromo- and meta-trifluoromethylanilines starting from 3-tribromomethylcyclopentanone or 3-(2-bromo-2-chloro-1,1,1-trifluoroethyl)cyclopentanone, resp. was reported. The scope of the transformation was shown by application of primary, secondary and aromatic amines. The reaction proceeded in acceptable to high yields (20-81%), and allows for the synthesis of anilines with substitution patterns otherwise difficult to access. In the experiment, the researchers used many compounds, for example, (R)-2-Aminobutan-1-ol (cas: 5856-63-3COA of Formula: C4H11NO).

(R)-2-Aminobutan-1-ol (cas: 5856-63-3) belongs to alcohols. The oxygen atom of the strongly polarized O―H bond of an alcohol pulls electron density away from the hydrogen atom. This polarized hydrogen, which bears a partial positive charge, can form a hydrogen bond with a pair of nonbonding electrons on another oxygen atom. Tertiary alcohols cannot be oxidized at all without breaking carbon-carbon bonds, whereas primary alcohols can be oxidized to aldehydes or further oxidized to carboxylic acids.COA of Formula: C4H11NO

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Alcohol – Wikipedia,
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Chemical control of mammalian circadian behavior through dual inhibition of casein kinase Iα and δ was written by Lee, Jae Wook;Hirota, Tsuyoshi;Ono, Daisuke;Honma, Sato;Honma, Ken-ichi;Park, Keunwan;Kay, Steve A.. And the article was included in Journal of Medicinal Chemistry in 2019.Application of 5856-63-3 This article mentions the following:

Circadian rhythms are controlled by transcriptional feedback loops of clock genes and proteins. The stability of clock proteins is regulated by post-translational modification, such as phosphorylation by kinases. In particular, casein kinase I (CKI) phosphorylates the PER protein to regulate proteasomal degradation and nuclear localization. Therefore, CKI inhibition can modulate mammalian circadian rhythms. In the present study, we have developed novel CKIα and CKIδ dual inhibitors by extensive structural modification of N9 and C2 position of longdaysin. We identified NCC007 (I) that showed stronger period effects (0.32 μM for 5 h period lengthening) in a cell-based circadian assay. The following in vitro kinase assay showed that I inhibited CKIα and CKIδ with an IC₅₀ of 1.8 and 3.6 μM. We further demonstrated that I lengthened the period of mouse behavioral rhythms in vivo. Thus, I is a valuable tool compound to control circadian rhythms through CKI inhibition. In the experiment, the researchers used many compounds, for example, (R)-2-Aminobutan-1-ol (cas: 5856-63-3Application of 5856-63-3).

(R)-2-Aminobutan-1-ol (cas: 5856-63-3) belongs to alcohols. Alcohols are weak acids. The most acidic simple alcohols (methanol and ethanol) are about as acidic as water, and most other alcohols are somewhat less acidic. Alcohols may be oxidized to give ketones, aldehydes, and carboxylic acids. These functional groups are useful for further reactions. Oxidation of organic compounds generally increases the number of bonds from carbon to oxygen (or another electronegative element, such as a halogen), and it may decrease the number of bonds to hydrogen.Application of 5856-63-3

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Alcohol – Wikipedia,
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The first application of C₂-symmetric ferrocenyl phosphinite ligands for rhodium-catalyzed asymmetric transfer hydrogenation of various ketones was written by Ak, Bunyamin;Aydemir, Murat;Durap, Feyyaz;Meric, Nermin;Baysal, Akin. And the article was included in Inorganica Chimica Acta in 2015.Name: (R)-2-Aminobutan-1-ol This article mentions the following:

Homogeneous catalysis has been responsible for many major recent developments in synthetic organic chem. The combined use of organometallic and coordination chem. has produced a number of new and powerful synthetic methods for important classes of compounds in general and for optically active substances in particular. For this aim, a new class of chiral modular C₂-sym. ferrocenyl phosphinite ligands has been prepared in good yields by using the inexpensive 1,1′-ferrocenedicarboxyaldehyde and various ferrocene based-amino alcs. as starting materials, and applied in the rhodium(I)-catalyzed asym. transfer hydrogenation (ATH) of aromatic ketones to give corresponding secondary alcs. with excellent enantioselectivities and reactivities using isoPrOH as the hydrogen source (up to 99% conversion and 99% ee). The substituents on the backbone of the ligands are found to exhibit a remarkable effect on both the activity and % ee. The structures of these ligands and their complexes have been elucidated by a combination of multinuclear NMR spectroscopy, IR spectroscopy and elemental anal. In the experiment, the researchers used many compounds, for example, (R)-2-Aminobutan-1-ol (cas: 5856-63-3Name: (R)-2-Aminobutan-1-ol).

(R)-2-Aminobutan-1-ol (cas: 5856-63-3) belongs to alcohols. Because alcohols are easily synthesized and easily transformed into other compounds, they serve as important intermediates in organic synthesis. Tertiary alcohols cannot be oxidized at all without breaking carbon-carbon bonds, whereas primary alcohols can be oxidized to aldehydes or further oxidized to carboxylic acids.Name: (R)-2-Aminobutan-1-ol

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Alcohol – Wikipedia,
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An ionic-based carbon dot for enantioselective discrimination of nonaromatic amino alcohols was written by Wu, Datong;Pan, Fei;Gao, Li;Tao, Yongxin;Kong, Yong. And the article was included in Analyst (Cambridge, United Kingdom) in 2020.Quality Control of (R)-2-Aminobutan-1-ol This article mentions the following:

Here, ionized chiral carbon dots, (S,S)-C-dots-1 (λ_ex = 430 nm, λ_em = 480 nm), were synthesized via a facile route with relatively high quantum yield (~24.4%) and used as a fluorescent chiral sensor. One of the advantages of the synthetic process is that it avoids the loss of the chiral center. That is, the chiral bromo compound can directly form an ionic pair with the pyridyl group, which is derived from the amine precursor in the first step. Furthermore, (S,S)-C-dots-1 shows clear discrimination toward different configurations of nonaromatic amino alcs. in the presence of Cu(II). When the (R)-isomer is added to a solution of (S,S)-C-dots-1 + Cu(II), it shows much higher fluorescent intensity than the (S)-isomer. The values of I_R/I_S are 2.9 and 2.3 for 2-aminobutan-1-ol and 2-aminopropan-1-ol, resp. In summary, we believe that this work can expand the synthetic routes and potential applications of functional carbon dots in the field of enantioselective sensing. In the experiment, the researchers used many compounds, for example, (R)-2-Aminobutan-1-ol (cas: 5856-63-3Quality Control of (R)-2-Aminobutan-1-ol).

(R)-2-Aminobutan-1-ol (cas: 5856-63-3) belongs to alcohols. The oxygen atom of the strongly polarized O―H bond of an alcohol pulls electron density away from the hydrogen atom. This polarized hydrogen, which bears a partial positive charge, can form a hydrogen bond with a pair of nonbonding electrons on another oxygen atom. Under carefully controlled conditions, simple alcohols can undergo intermolecular dehydration to give ethers. This reaction is effective only with methanol, ethanol, and other simple primary alcohols.Quality Control of (R)-2-Aminobutan-1-ol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Synthesis of rigid and C₂-symmetric pyridino-15-crown-5 type macrocycles bearing diamide-diester functions: enantiomeric recognition for chiral primary organoammonium perchlorate salts was written by Seker, Sevil;Baris, Deniz;Arslan, Nevin;Turgut, Yilmaz;Pirinccioglu, Necmettin;Togrul, Mahmut. And the article was included in Tetrahedron: Asymmetry in 2014.Application of 5856-63-3 This article mentions the following:

Four novel C₂-sym. macrocyclic compounds with a pyridine function and possessing amide and ester linkages were prepared The enantiomeric discrimination abilities of these macrocycles against α-phenylethylammonium and α-(1-naphthyl)ethylammonium perchlorate salts were measured by standard ¹H NMR titration techniques in DMSO-d₆. A binding constant ratio of 31 (Kbind(S)/Kbind(R)) for two enantiomers of α-(1-naphthyl)ethylammonium salt with the macrocyclic host (S,S)-4 bearing Ph arms was observed, which corresponds to an enantiomeric discrimination of ∼94%. Mol. dynamic calculations were performed for some of the supramol. complexes to gain insight into the mode of mol. recognition between the macrocyclic compounds and ammonium salts; these results were consistent with exptl. observations, which may be relevant to those in biochem. processes occurring in organisms. In the experiment, the researchers used many compounds, for example, (R)-2-Aminobutan-1-ol (cas: 5856-63-3Application of 5856-63-3).

(R)-2-Aminobutan-1-ol (cas: 5856-63-3) belongs to alcohols. A strong base can deprotonate an alcohol to yield an alkoxide ion (R―O−). For example, sodamide (NaNH2), a very strong base, abstracts the hydrogen atom of an alcohol. Converting an alcohol to an alkene requires removal of the hydroxyl group and a hydrogen atom on the neighbouring carbon atom. Dehydrations are most commonly carried out by warming the alcohol in the presence of a strong dehydrating acid, such as concentrated sulfuric acid.Application of 5856-63-3

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Multifunctional self-healing eutectogels induced by supramolecular assembly for smart conductive materials, interface lubrication and dye adsorption was written by Fan, Kaiqi;Wang, Lei;Wei, Wangchong;Wen, Fuqiang;Xu, Yunhan;Zhang, Xiaojing;Guan, Xidong. And the article was included in Chemical Engineering Journal (Amsterdam, Netherlands) in 2022.Safety of 1,2-Propanediol This article mentions the following:

The self-healing eutectogels with multifunctionality have attracted much attention in soft materials owing to their high conductivity and non-volatility. However, obtaining eutectogels with complete recovery of mech. properties is still challenging. Herein, we developed a series of halogenated dibenzylidene-D-sorbitol (X-DBS) gelators. The X-DBS could form eutectogels in deep eutectic solvents obtained from choline chloride combined with alcs. or urea, which exhibit self-healing, complete recovery, load-bearing, and injectability. Fourier transform IR, ¹⁹F NMR, and mol. dynamics simulations showed that the hydrogen bond between the C-F bond and the solvent mol. is key to the self-healing property of the eutectogels. Interestingly, the high ionic conductivity and self-healing property of our eutectogel make it potentially useful in a smart ionic conductor. Moreover, the self-healing eutectogels with corrosion resistance showed good lubricating performances on steel interfaces. In addition, the eutectogels showed excellent dye adsorption, effectively removing dyes from aqueous solutions Thus, the efficient DBS-based eutectogels with self-healing properties are excellent candidates for conductive materials, interfacial lubrication, dye adsorption, and other applications. In the experiment, the researchers used many compounds, for example, 1,2-Propanediol (cas: 57-55-6Safety of 1,2-Propanediol).

1,2-Propanediol (cas: 57-55-6) belongs to alcohols. A strong base can deprotonate an alcohol to yield an alkoxide ion (R―O−). For example, sodamide (NaNH2), a very strong base, abstracts the hydrogen atom of an alcohol. Under carefully controlled conditions, simple alcohols can undergo intermolecular dehydration to give ethers. This reaction is effective only with methanol, ethanol, and other simple primary alcohols.Safety of 1,2-Propanediol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Filtering the NMR Spectra of Mixtures by Coordination to Paramagnetic Cu²⁺ was written by Correa, Juan;Garcia-Barandela, Ana;Socias-Pinto, Llorenc;Fernandez-Megia, Eduardo. And the article was included in Analytical Chemistry (Washington, DC, United States) in 2022.Recommanded Product: 5856-63-3 This article mentions the following:

The paramagnetic spin relaxation (PSR) filter allows the selective NMR signal suppression of components in mixtures according to their complexation ability to a paramagnetic ion. It relies on the faster relaxation of nuclei in paramagnetic environments and thus is complementary to classical diffusion and relaxation filters. So far, the PSR filter has established Gd³⁺ as the sole PSR agent, restricting the paramagnetic filtering repertoire. Herein, we present Cu²⁺ as a robust PSR agent with characteristic filtering properties. While Gd³⁺ depends on unspecific ion-pair interactions with anionic components, Cu²⁺ stands out for filtering species via ordered coordination complexes. An evaluation of the paramagnetic effect of Cu²⁺ over more than 50 small mols. and polymers has unveiled different sensitivities to Cu²⁺ (especially high for pyridines, diamines, polyamines, and amino alcs.) and precise filtering conditions for mixtures (¹H, COSY, and HMQC) that were challenged with a test bed of com. drugs. The advantage of integrating Cu²⁺ and Gd³⁺ for the stepwise PSR filtering of complex mixtures is also shown. In the experiment, the researchers used many compounds, for example, (R)-2-Aminobutan-1-ol (cas: 5856-63-3Recommanded Product: 5856-63-3).

(R)-2-Aminobutan-1-ol (cas: 5856-63-3) belongs to alcohols. A strong base can deprotonate an alcohol to yield an alkoxide ion (R―O−). For example, sodamide (NaNH2), a very strong base, abstracts the hydrogen atom of an alcohol. Alcohols may be oxidized to give ketones, aldehydes, and carboxylic acids. These functional groups are useful for further reactions. Oxidation of organic compounds generally increases the number of bonds from carbon to oxygen (or another electronegative element, such as a halogen), and it may decrease the number of bonds to hydrogen.Recommanded Product: 5856-63-3

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts