Category: 96-76-4

On September 15, 2021, Xiong, Junping; Zhang, Dejin; Yang, Guoqiang; Zhang, Zhibing published an article.Computed Properties of 96-76-4 The title of the article was Alkylation of Phenol and tert-Butyl Alcohol Catalyzed by Deep Eutectic Solvents under Mild Conditions. And the article contained the following:

Tert-Bu phenol is an important intermediate for organic synthesis and the preparation of tert-Bu phenol under mild conditions is of great significance. In our work, five kinds of deep eutectic solvents were synthesized to catalyze the alkylation of phenol and tert-Bu alc. The deep eutectic solvent consisting of choline bisulfate (ChBf) and p-toluene sulfonic acid (p-TsOH) was proved to be a better catalyst. By employing the response surface methodol. to optimize the reaction conditions, we found that 99.5% conversion of tert-Bu alc. was obtained at a reaction temperature of 30°C. The temperature of alkylation reaction was much milder than those in previous reports. The kinetic model for this reaction was established based on the Runge-Kutta-Fehlberg method and the recycle performance for the catalyst was evaluated. Excellent conversion of tert-Bu alc. can be obtained after recycling eight times. This method provides a potential route for the synthesis of tert-Bu phenol under mild conditions in industry. The experimental process involved the reaction of 2,4-Di-tert-butylphenol(cas: 96-76-4).Computed Properties of 96-76-4

The Article related to phenol tert butanol alkylation catalyst deep eutectic solvents, Industrial Organic Chemicals, Leather, Fats, and Waxes: Manufacture Of Industrial Organic Chemicals and other aspects.Computed Properties of 96-76-4

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On September 6, 2022, Zhang, Dejin; Sun, Shu; Wu, Qi; Xie, Yong; Liu, Chengcheng; Wang, Cong; Zhang, Keying; Shi, Hongwei; Zhuo, Xin; Wang, Hongyan published an article.HPLC of Formula: 96-76-4 The title of the article was Efficient and Easily Recyclable Catalyst for the Alkylation Reaction of Phenol and tert-Butyl Alcohol. And the article contained the following:

Tert-Butylphenol is widely used as an intermediate in organic synthesis, and the catalyst for the alkylation reaction of phenol and tert-Bu alc. is the key to synthesizing tert-butylphenol. In our work, a catalyst, 1H-imidazole-1-acetic acid tosilate ([HIMA]OTs), was synthesized and characterized, and an efficient and easily recyclable catalytic system of an ionic liquid was established. In addition, the kinetic and thermodn. parameters were calculated; the pos. value of ΔH* indicated the endothermic nature of the alkylation reaction, and the pos. value of ΔS* and neg. value of ΔG* implied that the process of alkylation of phenol and tert-Bu alc. was spontaneous in the current reaction system. The recovery experiments of [HIMA]OTs were performed, and an excellent recycling performance was obtained. This method provides a potential way for the industrial synthesis of tert-butylphenol. The experimental process involved the reaction of 2,4-Di-tert-butylphenol(cas: 96-76-4).HPLC of Formula: 96-76-4

The Article related to efficient recyclable catalyst alkylation reaction phenol tert butyl alc, Industrial Organic Chemicals, Leather, Fats, and Waxes: Manufacture Of Industrial Organic Chemicals and other aspects.HPLC of Formula: 96-76-4

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On August 31, 2020, Agrawal, D.; De, S. K.; Singh, P. K.; Shrivastava, Y. published an article.Application In Synthesis of 2,4-Di-tert-butylphenol The title of the article was Synthesis of a novel post-metallocene titanium complex of chelating [ONOO]-type ligand and studies on the effect of an extra donor arm on its reactivity in aqueous emulsion polymerization. And the article contained the following:

In the present work, a new Ti complex LTiCl2 {LH2 = 2-(3,5-di-tert-butyl-2-hydroxybenzylamino)-succinic acid}-bearing tetradentate [ONOO] donors has been synthesized and used in the homopolymerization of Me methacrylate and styrene in aqueous emulsion. The effect of co-catalyst NaBPh4 with ion-pair BPh-4 was also studied on the catalytic activity. Moreover, synthesized complex has been characterized by 1H NMR, UV-visible spectroscopy, IR spectroscopy, high-resolution mass spectra and elemental anal. The fabricated polymers have been tested using different characterizations, viz. 1H NMR, 13C NMR, DSC, DLS, XRD and GPC anal. The GPC anal. reveals that polymer product obtained has high mol. weight, and the amorphous behavior of the polymer product was indicated by the XRD and DSC anal. In addition to this, kinetic parameters like activation energy and rate constant for polymethyl methacrylate have also been examined The experimental process involved the reaction of 2,4-Di-tert-butylphenol(cas: 96-76-4).Application In Synthesis of 2,4-Di-tert-butylphenol

The Article related to methyl methacrylate styrene polymerization metallocene titanium tetradentate ligand catalyst, Chemistry of Synthetic High Polymers: Polymerization Kinetics, Mechanisms, Thermodynamics, Catalysis, Catalysts and other aspects.Application In Synthesis of 2,4-Di-tert-butylphenol

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On April 30, 2020, Vol’eva, V. B.; Zhorin, V. A.; Ovsyannikova, M. N.; Kurkovskaya, L. N. published an article.Computed Properties of 96-76-4 The title of the article was Solid-Phase ortho-Hydroxylation of 2,4-Di-tert-butylphenol and Its Derivatives. And the article contained the following:

Direct phenol-catechol conversion was realized as a result of the solid-phase reaction of 2,4-di-tert-butylphenol with cuprous oxide under high pressure and shear deformation on the Bridgman anvils. The yield of 3,5-di-tert-butylcatechol in this reaction was about 85%. When cupric oxide was used in the solid-phase process, oxidative coupling of the starting phenol took place, resulting in quant. formation of tetra-tert-butyl-ortho-bisphenol. The reaction of 6-substituted derivatives of 2,4-di-tert-butylphenol with cuprous oxide was used as an example to demonstrate the possibility of substitutive ortho-hydroxylation yielding 7-20% of pyrocatechols. The experimental process involved the reaction of 2,4-Di-tert-butylphenol(cas: 96-76-4).Computed Properties of 96-76-4

The Article related to hydroxy ditertiary butylphenol preparation, ditertiary butylphenol ortho hydroxylation, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Phenols, Thiophenols, and Derivatives Including Phenol and Thiophenol Ethers and Esters and other aspects.Computed Properties of 96-76-4

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On December 31, 2021, Bhanderi, Khushboo; Ghalsasi, Prasanna S.; Inoue, Katsuya published an article.Computed Properties of 96-76-4 The title of the article was Nonconventional driving force for selective oxidative C-C coupling reaction due to concurrent and curious formation of Ag0. And the article contained the following:

Herein, reduction of [Ag(NH3)2]+ to Ag0 with concurrent oxidation of different phenols/naphthols to biphenyls was undertaken. The work was originated during careful observation of an undergraduate experiment-Tollen’s test-where silver mirror film deposition takes place on the walls of borosilicate glass test tube. When the same reaction was carried out in polypropylene (plastic-Eppendorf) tube, aggregation of Ag0 leading to floating Ag-particles was observed but not silver film deposition. This prompted to carry out challenging cross-coupling reaction by only changing the surface of the reaction flask from glass to plastic to silicones. Surprisingly, good selective oxidative homo-coupling on Teflon surface while cross-coupling in Eppendorf vial was observed Thus, the formation of biphenyl is driven by the macroscopic growth of Ag0 into [Ag-particle] orchestrated by Ag…Ag cohesive interaction was proposed. To validate results, experiments were also performed on gram scale. More importantly, oxidation of β-naphthol carried out in quartz (chiral) tube which yielded slight enantioselective excess of BINOL. The experimental process involved the reaction of 2,4-Di-tert-butylphenol(cas: 96-76-4).Computed Properties of 96-76-4

The Article related to phenol silver ammonia complex catalyst regieoselective oxidative coupling, biphenyl preparation, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Phenols, Thiophenols, and Derivatives Including Phenol and Thiophenol Ethers and Esters and other aspects.Computed Properties of 96-76-4

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Zarraga O., M.; Darouch, M.; Lisboa, E.; Arroyo P., P.; Miranda M., A. published an article in 2021, the title of the article was Synthesis of 6-tert-octyl and 6,8-ditert-butyl coumarins, two coumarins of biological interest.Product Details of 96-76-4 And the article contains the following content:

In this study, the synthesis of new coumarins with aliphatic chains is discussed. The incorporation of the 6-tert-octyl and 6,8-ditert-Bu chains into a coumarin structure from alkylphenols, allows obtaining hydrophobic coumarins with good yields. These coumarins can be potential modulators of TRPV1 receptors. Synthesis and spectroscopic data of these new coumarins are analyzed. The experimental process involved the reaction of 2,4-Di-tert-butylphenol(cas: 96-76-4).Product Details of 96-76-4

The Article related to tert octyl ditert butyl coumarin preparation, Heterocyclic Compounds (One Hetero Atom): Benzopyrans (Including Coumarins, Isocoumarins, Chromones, Benzopyrones, Dibenzopyrans, and Other Arenopyrans) and other aspects.Product Details of 96-76-4

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On August 12, 2022, Liu, Bowen; Wang, Lei; Qin, Yunfei; Xu, Xianxiu; Zhao, Jinbo published an article.Recommanded Product: 2,4-Di-tert-butylphenol The title of the article was Synthesis of Trisubstituted Chromanes by Lewis-Base-Catalyzed Three-Component Electrophilic Thiofunctionalization of Cyclopropene with Phenols via a Formal [3 + 3] Annulation. And the article contained the following:

A Lewis-base-catalyzed three-component electrophilic thiofunctionalization of cyclopropene with phenol is developed to furnish various trisubstituted chromanes in high trans-diastereoselectivity. This metal-free protocol is easy to scale-up, offers a unique 2,2,3-substitution pattern, and delivers chromanes with diversified core substitution patterns. The unprecedented tolerance of strong electron-withdrawing substituents at the phenol renders the protocol indispensable to access the otherwise inaccessible chromane chem. space that is important for medicinal chem. campaigns. The experimental process involved the reaction of 2,4-Di-tert-butylphenol(cas: 96-76-4).Recommanded Product: 2,4-Di-tert-butylphenol

The Article related to alkyl aryl arylthio chromane preparation diastereoselective triphenylphosphine sulfide antitumor, phenol cyclopropene phenylsulfenyl phthalimide annulation, Heterocyclic Compounds (One Hetero Atom): Benzopyrans (Including Coumarins, Isocoumarins, Chromones, Benzopyrones, Dibenzopyrans, and Other Arenopyrans) and other aspects.Recommanded Product: 2,4-Di-tert-butylphenol

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On September 7, 2020, Kraszewski, Karol; Tomczyk, Ireneusz; Drabinska, Aneta; Bienkowski, Krzysztof; Solarska, Renata; Kalek, Marcin published an article.Name: 2,4-Di-tert-butylphenol The title of the article was Mechanism of Iodine(III)-Promoted Oxidative Dearomatizing Hydroxylation of Phenols: Evidence for a Radical-Chain Pathway. And the article contained the following:

The oxidative dearomatization of phenols with the addition of nucleophiles to the aromatic ring induced by hypervalent iodine(III) reagents and catalysts has emerged as a highly useful synthetic approach. However, exptl. mechanistic studies of this important process have been extremely scarce. In this report, we describe systematic investigations of the dearomatizing hydroxylation of phenols using an array of exptl. techniques. Kinetics, EPR spectroscopy, and reactions with radical probes demonstrate that the transformation proceeds by a radical-chain mechanism, with a phenoxyl radical being the key chain-carrying intermediate. Moreover, UV and NMR spectroscopy, high-resolution mass spectrometry, and cyclic voltammetry show that before reacting with the phenoxyl radical, the water mol. becomes activated by the interaction with the iodine(III) center, causing the Umpolung of this formally nucleophilic substrate. The radical-chain mechanism allows the rationalization of all existing observations regarding the iodine(III)-promoted oxidative dearomatization of phenols. The experimental process involved the reaction of 2,4-Di-tert-butylphenol(cas: 96-76-4).Name: 2,4-Di-tert-butylphenol

The Article related to phenol iodine oxidative dearomatization kinetics mechanism, hypervalent iodine, mechanistic investigations, phenol dearomatization, radical-chain pathway, synthetic methods and other aspects.Name: 2,4-Di-tert-butylphenol

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On August 17, 2021, Lowe, Charles N.; Phillips, Katherine A.; Favela, Kristin A.; Yau, Alice Y.; Wambaugh, John F.; Sobus, Jon R.; Williams, Antony J.; Pfirrman, Ashley J.; Isaacs, Kristin K. published an article.Related Products of 96-76-4 The title of the article was Chemical Characterization of Recycled Consumer Products Using Suspect Screening Analysis. And the article contained the following:

Recycled materials are found in many consumer products as part of a circular economy; however, the chem. content of recycled products is generally uncharacterized. A suspect screening anal. using two-dimensional gas chromatog. time-of-flight mass spectrometry (GC x GC-TOFMS) was applied to 210 products (154 recycled, 56 virgin) across seven categories. Chems. in products were tentatively identified using a standard spectral library or confirmed using chem. standards A total of 918 probable chem. structures identified (112 of which were confirmed) in recycled materials vs. 587 (110 confirmed) in virgin materials. Identified chems. were characterized in terms of their functional use and structural class. Recycled paper products and construction materials contained greater numbers of chems. than virgin products; 733 identified chems. had greater occurrence in recycled compared to virgin materials. Products made from recycled materials contained greater numbers of fragrances, flame retardants, solvents, biocides, and dyes. The results were clustered to identify groups of chems. potentially associated with unique chem. sources, and identified chems. were prioritized for further study using high-throughput hazard and exposure information. While occurrence is not necessarily indicative of risk, these results can be used to inform the expansion of existing models or identify exposure pathways currently neglected in exposure assessments. The experimental process involved the reaction of 2,4-Di-tert-butylphenol(cas: 96-76-4).Related Products of 96-76-4

The Article related to chem recycled consumer product suspect screening, expocast, consumer exposure, consumer products, human exposure modeling, nontargeted analysis, recycling, suspect screening and other aspects.Related Products of 96-76-4

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On January 15, 2022, Sun, Nan; Gao, Zhiyi; Li, Shiqi; Chen, Xiaowen; Guo, Jing published an article.Reference of 2,4-Di-tert-butylphenol The title of the article was Assessment of chemical constitution and aroma properties of kiwi wines obtained from pure and mixed fermentation with Wickerhamomyces anomalus and Saccharomyces cerevisiae. And the article contained the following:

To improve the aroma of kiwi wine through the utilization of Wickerhamomyces anomalus, kiwi juice was fermented using a selected W. anomalus strain in pure culture and mixed fermentations with Saccharomyces cerevisiae, which was inoculated simultaneously and sequentially. The physicochem. indexes, volatile compounds and aroma properties of the kiwi wines were assessed. The study suggested that the ethanol, color indexes and organic acids of the wines were closely related to the method of inoculation. Compared with the pure S. cerevisiae fermentation, the mixed fermentations produced more varieties and concentrations of volatiles. The sequential fermentations increased the concentrations of esters and terpenes, improving the flower and sweet fruit notes of the wines. The simultaneous inoculation enhanced the contents of esters and aldehydes, intensifying the flower, sweet and sour fruit of the wines. Partial least-squares regression anal. showed that esters and terpenes contributed greatly to the flower and sweet fruit aroma, whereas aldehydes were the major contributors to the sour note. Based on our results, the mixed fermentations not only enriched the types and concentrations of volatiles, but also had better sensory properties. The experimental process involved the reaction of 2,4-Di-tert-butylphenol(cas: 96-76-4).Reference of 2,4-Di-tert-butylphenol

The Article related to ester aldehyde terpene kiwi wine aroma wickerhamomyces saccharomyces fermentation, wickerhamomyces anomalus, kiwi wine, mixed fermentations, partial least squares regression and other aspects.Reference of 2,4-Di-tert-butylphenol

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