Category: 96-76-4

On June 30, 2021, Mayasich, Sally A.; Korte, Joseph J.; Denny, Jeffrey S.; Hartig, Phillip C.; Olker, Jennifer H.; DeGoey, Philip; O’Flanagan, Joseph; Degitz, Sigmund J.; Hornung, Michael W. published an article.Electric Literature of 96-76-4 The title of the article was Xenopus laevis and human type 3 iodothyronine deiodinase enzyme cross-species sensitivity to inhibition by ToxCast chemicals. And the article contained the following:

Deiodinase enzymes are critical for tissue-specific and temporal control of activation or inactivation of thyroid hormones during vertebrate development, including amphibian metamorphosis. We previously screened ToxCast chems. for inhibitory activity toward human recombinant Type 3 iodothyronine deiodinase enzyme (hDIO3) and subsequently produced Xenopus laevis recombinant dio3 enzyme (Xldio3) with the goals to identify specific chem. inhibitors of Xldio3, to evaluate cross-species sensitivity and explore whether the human assay results are predictive of the amphibian. We identified a subset of 356 chems. screened against hDIO3 to test against Xldio3, initially at a single concentration (200μM), and further tested 79 in concentration-response mode. Most chems. had IC50 values lower for hDIO3 than for Xldio3 and many had steep Hill slopes (a potential indication of non-specific inhibition). However, eight of the most potent chems. are likely specific inhibitors, with IC50 values of 14μM or less, Hill slopes near -1 and curves not significantly different between species likely due to conservation of catalytically active amino acids. Controlling for assay conditions, human in vitro screening results can be predictive of activity in the amphibian assay. This study lays the groundwork for future studies using recombinant non-mammalian proteins to test cross-species sensitivity to chems. The views expressed in this paper are those of the authors and do not necessarily reflect the views or policies of the U. The experimental process involved the reaction of 2,4-Di-tert-butylphenol(cas: 96-76-4).Electric Literature of 96-76-4

The Article related to xenopus human iodothyronine deiodinase screening endocrine disruptor, deiodinase, endocrine disruption, screening, thyroid, xenopus laevis, Toxicology: Methods (Including Analysis) and other aspects.Electric Literature of 96-76-4

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On December 31, 2021, Singh, Lalita; Antil, Reena; Dahiya, Pushpa published an article.Synthetic Route of 96-76-4 The title of the article was Antimicrobial and Antioxidant Potential of Vernonia Cinerea Extract Coated AuNPs. And the article contained the following:

Abstract: Green synthesis of nanoparticles is an important tool to reduce the harmful effects associated with traditional methods. In the present investigation, we have synthesized gold nanoparticles (AuNPs) using aqueous extract prepared from fresh aerial parts (leaf and stem) of Vernonia cinerea as bioreducing agent. The visual indication of change in color from pale yellow to brown to ruby-red indicated the successful formation of the AuNPs. Characterization of nanoparticles was carried out by UV-visible spectroscopy, X-ray crystallog. (XRD), Transmission electron microscopy (TEM) and Energy dispersive X-ray anal. (EDX). UV-Vis spectra showed a specific peak at 546 nm which was the initial confirmation of the biosynthesized AuNPs. TEM images showed spherical and triangular shape of AuNPs with an average size of 25 nm. From FTIR spectrum, different functional groups were identified that could be responsible for the formation, stabilization, and capping of biosynthesized AuNPs. Aqueous plant extract and biosynthesised AuNPs were sep. tested for their antimicrobial activity against six bacterial strains and four fungal strains. Biosynthesised AuNPs (2 mg/mL) showed significantly high zone of inhibition against the selected bacterial strains as compared to the aqueous plant extract Maximum zone of inhibition (18.2 mm) was observed with AuNPs against Streptococcus pyogenes whereas comparatively less value (12.5 mm) was recorded with the plant extract Interestingly, the inhibitory activity observed against bacterial strains was even better than ampicillin. Antifungal activity recorded with AuNPs (5 mg/mL) was maximum (17.4 mm) against R. oryzae and it was higher than pos. control (17.00 mm) and plant extract (13.2 mm). The present study clearly showed that AuNPs coated with Vernonia cinerea extract were as good as pos. control in inhibiting bacterial and fungal growth. In addition, these AuNPs also showed good antioxidant potential which was comparable to ascorbic acid. Graphical abstract: [graphic not available: see fulltext]. The experimental process involved the reaction of 2,4-Di-tert-butylphenol(cas: 96-76-4).Synthetic Route of 96-76-4

The Article related to vernonia aqueous extract gold nanoparticle synthesis antimicrobial, antifungal activity, antimicrobial activity, gold nanoparticles, vernonia cinerea, Pharmaceuticals: Pharmacognostic Products and other aspects.Synthetic Route of 96-76-4

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On August 15, 2022, Ma, Jian; Ma, Yanhong; Zhang, Hongzhi; Chen, Zhiling; Wen, Bo; Wang, Yu; Huang, Wuyang published an article.Safety of 2,4-Di-tert-butylphenol The title of the article was The quality change of fig wine fermented by RV171 yeast during the six-month aging process. And the article contained the following:

In the present study, the objective was to determine the quality changes of fig wine fermented with single yeast during six months of aging process. The suitable single yeast was screened, and the optimal fermentation process was determined through single-factor exptl. anal. and response surface methodol. The fig wine prepared by the optimal fermentation process then aged for six months. The results showed that the strain RV171 was the most suitable yeast among six evaluated yeast strains. The optimal process conditions were yeast addition 0.3%, fermentation temperature 28 °C, and fermentation time 9 days. During the aging process, the contents of vitamin C, total phenolics and flavonoids, as well as antioxidant activity of fig wine changed significantly. There was a pos. correlation between these bioactive substances and antioxidant capacity. In addition, significant differences existed for volatile aroma compounds in fig wine at different aging times. When fig wine is aged for one month, the content of ester volatile components was the highest, while the aroma is better than the others. The present study could provide theor. basis for the production and aging process of fig wine, which would be helpful for further investigation and application of figs to functional foods. The experimental process involved the reaction of 2,4-Di-tert-butylphenol(cas: 96-76-4).Safety of 2,4-Di-tert-butylphenol

The Article related to ficus wine quality yeast fermentation aging process, Placeholder for records without volume info and other aspects.Safety of 2,4-Di-tert-butylphenol

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Yenuganti, Mahesh; Das, Sandip; Kulbir; Ghosh, Somnath; Bhardwaj, Prabhakar; Pawar, Sonali Shivaji; Sahoo, Subash Chandra; Kumar, Pankaj published an article in 2020, the title of the article was Nitric oxide dioxygenation (NOD) reactions of CoIII-peroxo and NiIII-peroxo complexes: NOD versus NO activation.Quality Control of 2,4-Di-tert-butylphenol And the article contains the following content:

Here, we report the nitric oxide dioxygenation (NOD) reactions of NiIII-peroxo, [(12-TMC)NiIII(O22-)]+ (NiIII-O22-, 1), and CoIII-peroxo, [(12-TMC)CoIII(O22-)]+ (CoIII-O22-, 2), complexes bearing N-tetramethylated cyclam (TMC) ligands. The reaction of complex 1 with nitric oxide (NO) generates NiII-nitrato complex [(12-TMC)NiII(NO3-)]+ (NiII-NO3-, 3). However, in contrast to the NOD reaction of 1, compound 2 produces CoII-nitrito complex, [(12-TMC)CoII(NO2-)]+ (CoII-NO2-, 4), with O2 gas formation. Results suggested the formation of a presumptive Ni-peroxynitrite ([Ni-PN]+, [Ni-ONOO-]+) intermediate, in the NOD reaction of 1, prior to the generation of NiII-NO3- (3). Although the end product of the reaction of 2 with NO is different from that of 1, the mechanistic study explored by using 2,4-di-tert-butylphenol (2,4-DTBP) suggested that the reaction of 2 with NO also occurs via a presumed Co-peroxynitrite ([Co-PN]+, [Co-ONOO-]+) intermediate. Furthermore, exploring these NOD reactions and tracking the oxygen atom using 18O-labeled hydrogen peroxide (H218O2) revealed that two oxygen atoms of 3 (NiII-18O2N16O-) and one oxygen atom of 4 (CoII-18ON16O-) are derived from the peroxo (O22-) moieties of 1 and 2, resp. This work is the first-ever report which showed the exact NO dioxygenase (NOD) enzyme catalytic cycle. Furthermore, we have also explored the NO activation of 3 and 4, and surprisingly, we observed the formation of Co-nitrosyl (5) from 4 upon reaction with NO; in contrast, 3 was unreactive towards NO. Evidence supporting the formation of [Ni-PN]+ and [Co-PN]+ intermediates is also presented. The experimental process involved the reaction of 2,4-Di-tert-butylphenol(cas: 96-76-4).Quality Control of 2,4-Di-tert-butylphenol

The Article related to cobalt nickel peroxo complex nitric oxide dioxygenation gas, Placeholder for records without volume info and other aspects.Quality Control of 2,4-Di-tert-butylphenol

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Cromwell, Benjamin; Mota, Lisa Cid; Levine, Mindy published an article in 2020, the title of the article was Detection of potentially toxic additives in electronic cigarettes and cigarette flavourings.COA of Formula: C14H22O And the article contains the following content:

While the popularity of electronic cigarettes (e-cigarettes) has rapidly increased in recent years, the regulation around the composition of such e-cigarettes has lagged. Many components of the e-cigarettes and liquid flavorings (e-liquids) used in these products are not disclosed, and the potential for exposure to toxic compounds via use of these products is significant. Reported herein is an anal. of the components of e-cigarettes as well as of three popular e-liquids via gas chromatog. – mass spectrometry. These results show that components of the e-cigarette contain large quantities of aromatic compounds, and that the e-liquids contain smaller quantities of potentially concerning additives. Most notably, 96% of the extract from the filter was composed of benzyl chloride, a potent DNA alkylating agent, a result which should be of significant concern to consumers, regulatory agencies, and e-cigarette manufacturers. The experimental process involved the reaction of 2,4-Di-tert-butylphenol(cas: 96-76-4).COA of Formula: C14H22O

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Chak, Pooja; Chaudhary, Deepti; Jain, Sonika; Soni, Priyanka; Jain, P. K.; Dwivedi, Jaya; Sharma, S. published an article in 2021, the title of the article was Phytochemical and gas chromatography-mass spectrometry analysis of Chenopodium album and Stellaria media.Category: alcohols-buliding-blocks And the article contains the following content:

The current study was designed to conduct the physicochem., phytochem. and gas chromatographymass spectrometry anal. of Chenopodium album and Stellaria media L. Obtained plant fractions were analyzed for the presence of different secondary metabolites using phytochem. screening methods. Results of phytochem. anal. revealed the presence of different secondary metabolites including flavonoids, phenols, alkaloids, tannins, glycosides and saponin. Further, gas chromatog.-mass spectrometry anal. indicated presence of total 30 and 31 phytoconstituents in hexane and Et acetate fractions of methanolic extract of Chenopodium album resp. whereas chloroform and Et acetate fractions of methanolic extract of Stellaria media showed presence of total 33 and 35 phytoconstituents resp. Gas chromatog.-mass spectrometry chromatogram showed abundance of polyphenolic compounds (85 Phenol-2,4-bis(1,1-dimethylethyl), phosphite (3:1) in hexane fractions of Chenopodium album, long-chain fatty acids (51 hexadecanoic acid, Me ester in chloroform fractions of Chenopodium album), higher alkanes (66 Octasiloxane- 1,1,3,3,5,5,7,7,9,9,11,11,13,13,15,15-hexadecamethyl in Et acetate fractions of Chenopodium album). Outcome of the study would certainly assist the investigators to explore these plants and to identify and develop new leads for the treatment of different pathol. conditions. The experimental process involved the reaction of 2,4-Di-tert-butylphenol(cas: 96-76-4).Category: alcohols-buliding-blocks

The Article related to stellaria chenopodium phytochem gas chromatog mass spectrometry, Placeholder for records without volume info and other aspects.Category: alcohols-buliding-blocks

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On July 31, 2021, Ahmad, K. S.; Hafeez, N.; Gul, M. M.; Ali, D.; Shaheen, A.; Aslam, B. published an article.HPLC of Formula: 96-76-4 The title of the article was Xenobiotic thiencarbazone-methyl biotransformation investigation by bacteria Streptococcus pneumoniae, Escherichia coli and Streptococcus pyogenes. And the article contained the following:

Abstract: Xenobiotic thiencarbazone-Me is a herbicide applied on various grasses and weeds. This triazolinone pesticide may be present in soil and water after application posing deleterious effects on environment and human health. The degradation of thiencarbazone-Me was scrutinized by the pure bacterial strains including Streptococcus pneumoniae (SP), Escherichia coli (EC) and Streptococcus pyogenes (SPy). Individual bacterial suspension was prepared with herbicide solution and evaluated for a duration of 28 days. Time-dependent sampling was performed to investigate thiencarbazone-Me degradation after specific days interval. Biotransformed samples were extracted and analyzed by UV-Vis spectrophotometer and GC-MS. Biodegradation percentage achieved by SP, Spy and EC, after 28 days, was 31, 40 and 65, resp. E. coli (R2= 0.91) displayed greatest potential among all the strains to degrade the herbicide. Significant residues formed included Me 4-isocyanatosulfonyl-5-methylthiophene-3-carboxylate, 4-methanesulfonyl-benzenesulfonic acid amide and Me 3-sulfamoylthiophene-2carboxylate. Current research elucidated the effectiveness of using bacterial strains for the bioremediation of pesticides in environment. The experimental process involved the reaction of 2,4-Di-tert-butylphenol(cas: 96-76-4).HPLC of Formula: 96-76-4

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Katada, Johanna Joy S.; Mangorangka, Musmera A.; Villena, Mark Ryan P.; Arquisal, Isidro B.; Morilla, Lady Jane; Mondejar, Eddie P. published an article in 2022, the title of the article was Characterization of bioactive compounds in the ant Leptogenys diminuta (Smith, 1857) using Gas Chromatography – Mass Spectrophotometry.COA of Formula: C14H22O And the article contains the following content:

Ants are one of the diverse groups of insects and are less explored reservoirs of many bioactive natural products, including proteins and peptides. This study was conducted to characterize the compounds of the worker ant, Leptogenys diminuta (Smith, 1857). Hence, this study will demonstrate the importance of ants as a potential source of bioactive compounds found in nature. Thirty samples of L. diminuta were extracted using hexane solution and the compounds were detected using Gas Chromatog.-Mass Spectrophotometry (GC-MS), and the mass spectra of compounds were identified using the NIST08 Standard Reference Database. The anal. identified seven bioactive compounds from L. diminuta with pharmacol. and industrial applications, including the first reports of the presence of 2,4-ditert-butylphenol in Ponerine worker ant′s hexane extract Thus, more studies are needed to explore other essential natural products with various applications found in ants. The experimental process involved the reaction of 2,4-Di-tert-butylphenol(cas: 96-76-4).COA of Formula: C14H22O

The Article related to leptogenys bioactive compound gas chromatog mass spectrophotometry, Placeholder for records without volume info and other aspects.COA of Formula: C14H22O

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Bhardwaj, Kanchan; Sharma, Rohit; Cruz-Martins, Natalia; Valko, Marian; Upadhyay, Navneet Kumar; Kuca, Kamil; Bhardwaj, Prerna published an article in 2022, the title of the article was Studies of phytochemicals, antioxidant, and antibacterial activities of Pinus gerardiana and Pinus roxburghii seed extracts.HPLC of Formula: 96-76-4 And the article contains the following content:

A review. Pine seeds are considered as nonwood forest products (NWFP) with regularly increasing market′s demand. They can be eaten in various ways such as roasted or raw. In addition, they are included in various traditional dishes like in cookies, sauces, candies, cakes, breads, and other bakery items and, moreover, for medicinal purposes. GC-MS study is performed to analyze the phytochem. compounds present in the seed extracts of Pinus roxburghii (Chir) and Pinus gerardiana (Chilgoza). In total, 25 compounds were identified each in Chir and Chilgoza. In Chir seeds, abundantly present compounds were 2,4-di-tert-butylphenol (16.6%), followed by gamma-Terpinene (9.9%) and cyclohexanol, 4-ethenyl-4-methyl-3-(1-methylethenyl)-, (1a,3a,4a) (9.8%), whereas in Chilgoza seeds, the maximum amount of compound was 1-hexyl-1-nitrocyclohexane (17.3%), followed by phenol, 2,6-bis(1,1-dimethylethyl) (15.4%), and heptadecane, 2-Me (8.4%). The total phenolic content of Chir seed sample was 1536 ± 4.35 (mg GAE/100 g), whereas in the Chilgoza seed extract was 642.66 ± 2.08 (mg GAE/100 g). The application of RP-HPLC-DAD system revealed that Chir and Chilgoza seeds have maximum quantity of catechin (15.77 ± 0.16 μg/mg and 17.49 ± 0.32 μg/mg, resp.). Both Chir and Chilgoza seed extracts exhibited significant antioxidant (radical scavenging) potential, through H2O2 (618.94 ± 21.45 μg/mL and 575.16 ± 19.88 μg/mL) and DPPH (552.60 ± 13.03 μg/mL and 429.15 ± 3.80 μg/mL) assays, resp. Addnl., a well-known antibacterial potential was also found in both plants dichloromethane extracts, with 64 to 256 μg/mL of min. inhibitory concentrations As a whole, result shows the importance of both plants as a naturally occurring phytochem. source with significant antibacterial and antioxidant activity. The experimental process involved the reaction of 2,4-Di-tert-butylphenol(cas: 96-76-4).HPLC of Formula: 96-76-4

The Article related to review pinus cyclohexanol catechin antioxidant antibacterial agent, Placeholder for records without volume info and other aspects.HPLC of Formula: 96-76-4

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Asaduzzaman, A. K. M.; Hasan, Imtiaj; Rahman, M. Habibur; Abu Rayhan, Mohammad Tareq published an article in 2020, the title of the article was Antioxidant and antiproliferative activity of phytoconstituents identified from Sargassum binderi seaweed extracts cultivated in Bangladesh.SDS of cas: 96-76-4 And the article contains the following content:

In the present study, seaweed Sargassum binderiwas extracted by the solvent ethanol and methanol. As phytoconstituents of both extracts were analyzed by gas chromatog.-mass spectrometry (GC-MS), eighteen and nineteen compounds have been found from the ethanolic extract and methanolic extract, resp. 1,2-Benzenedicarboxylic acid, diisooctyl esters was found in higher amounts and Pentadecanoic acid, 14-methyl-, Me ester was the other major compounds present in both extracts Total phenolic and flavonoid compounds were found to be as 11.890 mg gallic acid equivalent (GAE)/g and 269.542 mg catechin (CE)/g from ethanolic extract and 11.495 mg GAE/g and 266.936 mg CE/g from the methanolic extract Good percentages of scavenging activity of DPPH, ABTS, total antioxidant and ferric reducing power have been observed in both extracts 88.33% and 87.27% cell growth inhibition was observed in vitroat 176 μg/mL, resp. Both S. binderi extracts showed mild toxicity against brine shrimp nauplii with LC50 values of 106.66 μg/mL and 125.82 μg/mL, resp. Therefore we can say the ethanolic and methanolic extracts of S. binderi are a promising source of new mols. with possible applications as antioxidants and in cancer therapeutics. The experimental process involved the reaction of 2,4-Di-tert-butylphenol(cas: 96-76-4).SDS of cas: 96-76-4

The Article related to sargassum extract phytoconstituent antioxidant antiproliferative cancer, Placeholder for records without volume info and other aspects.SDS of cas: 96-76-4

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