Category: 96-20-8

Chakraborty, Shampa published the artcileRapid and efficient synthesis of 2,2-dimethylaminobenzazoles and 2,2-dimethylaminoazoles in a sustainable way, Synthetic Route of 96-20-8, the publication is Materials Research Innovations (2021), 25(2), 90-94, database is CAplus.

Reactions of 2-aminophenol, 2-aminobenzenethiol and other 2-substituted anilines, ethylene amines and amino acid containing 1,2 amino hydroxy groups with TBTU [2-(1H-benzotriazole-1-yl)-1,1,3,3-tetramethyluroniumtetrafluoroborate], easily formed corresponding benzazoles (single crystal X-ray structure) and azoles attached with a di-Me amino group at 2-position via a guanidine intermediate which cyclizes and aromatizes by eliminating one dimethylamino group to afford benzazoles and azoles. The nobality of the synthesis is, single step and can occur at ambient temperature

Materials Research Innovations published new progress about 96-20-8. 96-20-8 belongs to alcohols-buliding-blocks, auxiliary class Amine,Aliphatic hydrocarbon chain,Alcohol, name is 2-Aminobutan-1-ol, and the molecular formula is C4H11NO, Synthetic Route of 96-20-8.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Barzagli, Francesco published the artcileScreening study of different amine-based solutions as sorbents for direct CO₂ capture from air, Product Details of C4H11NO, the publication is ACS Sustainable Chemistry & Engineering (2020), 8(37), 14013-14021, database is CAplus.

Direct air capture (DAC) is an emerging technol. that can help limit the global temperature rises, as it has the potential to contrast the dispersed CO₂ emissions coming from transport and heating that cannot be captured with traditional CCS methods. Although recent improvements are bringing DAC closer to com. feasibility, an obstacle to its diffusion is the high regeneration energy required by the most common liquid sorbents, Na or K hydroxides. In order to develop efficient and more sustainable sorbents, in the present screening study several alkanolamines, particularly those already known for their utilization in CCS, were tested for DAC. The percentage of CO₂ absorbed from compressed air of their 1.5 mol dm^-3 aqueous solutions was evaluated in 24 h capture experiments and the species formed were identified and quantified by means of ¹³C-NMR spectroscopy. For selected amines, their performance in organic diluents was also evaluated. The correlations between aerial CO₂ absorption, chem. structures of the different amine and species formed in solution have shown that a high yield production of amine carbamate is the decisive factor for an effective CO₂ capture, and that aqueous primary unhindered amines are as efficient as aqueous alkali hydroxides, with the potential of a lower regeneration energy.

ACS Sustainable Chemistry & Engineering published new progress about 96-20-8. 96-20-8 belongs to alcohols-buliding-blocks, auxiliary class Amine,Aliphatic hydrocarbon chain,Alcohol, name is 2-Aminobutan-1-ol, and the molecular formula is C4H11NO, Product Details of C4H11NO.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Krasniqi, Besir published the artcileGeneral Transition Metal-Free Synthesis of NH-Pyrroles from Secondary Alcohols and 2-Aminoalcohols, Name: 2-Aminobutan-1-ol, the publication is Journal of Organic Chemistry (2019), 84(9), 5027-5034, database is CAplus and MEDLINE.

A novel, transition metal-free and one-pot methodol. to synthesize various substituted NH-pyrroles from readily available building blocks such as secondary alcs. and 2-aminoalcs. is described. The process is based on the venerable Oppenauer-Woodward oxidation, which uses benzophenone as an inexpensive reagent to achieve oxidation of secondary alcs. under mild condition to ketones, further in situ condensation with aminoalc., and oxidative cyclization to the target pyrrole ring. The reaction occurs under basic conditions, and features a broad substrate scope combined with very good tolerance for sensitive functional groups. This method can be used to synthesize various substituted pyrroles useful as a starting material for broad applications.

Journal of Organic Chemistry published new progress about 96-20-8. 96-20-8 belongs to alcohols-buliding-blocks, auxiliary class Amine,Aliphatic hydrocarbon chain,Alcohol, name is 2-Aminobutan-1-ol, and the molecular formula is C4H11NO, Name: 2-Aminobutan-1-ol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Zhang, Yuan-Yuan published the artcileProtective efficacy of phenoxyacetyl oxazolidine derivatives as safeners against nicosulfuron toxicity in maize, Application In Synthesis of 96-20-8, the publication is Pest Management Science (2021), 77(1), 177-183, database is CAplus and MEDLINE.

Herbicide safeners mitigate crop damage without reducing herbicide efficacy. Here, the protective effects of phenoxyacetyl oxazolidine derivatives as potential safeners were evaluated with a view toward reducing injury caused by sulfonylurea herbicide nicosulfuron to sensitive maize varieties. Growth indexes demonstrated that the bioactivity of compound 9 (N-phenoxyacety-2-methyl-2,4-diethyl-1,3-oxazolidine) was superior to that of R-28725 and all other compounds tested. Compound 9 induced endogenous glutathione and upregulated glutathione-S-transferase (GST) in maize. Thus, it could enhance maize tolerance to nicosulfuron. Compared with the untreated water control group, the maximum reaction rate of GST was increased by 37.62%, while the maximum velocity of GST was decreased by 61.93% after treatment with compound 9. Acetolactate synthase relative activity was significantly enhanced in the case of treatment with compound 9, indicating the excellent protective effects of compound 9 against nicosulfuron in maize. The present work demonstrates that phenoxyacetyl oxazolidine derivatives are potentially efficacious as herbicide safeners and merit further investigation.

Pest Management Science published new progress about 96-20-8. 96-20-8 belongs to alcohols-buliding-blocks, auxiliary class Amine,Aliphatic hydrocarbon chain,Alcohol, name is 2-Aminobutan-1-ol, and the molecular formula is CBF6K, Application In Synthesis of 96-20-8.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Paul, Aparup published the artcileDouble μ₂-(phenoxido)-bridged dinuclear and polynuclear nickel(II) complexes: Magnetic properties and DNA/protein interaction, Category: alcohols-buliding-blocks, the publication is Polyhedron (2019), 39-48, database is CAplus.

One dinuclear and one 1-dimensional polymeric Ni(II) complex, {[Ni₂(HL)₂(pa)₂(H₂O)₂]·DMF} (1) and {[Ni₂(HL)₂(ppda)(H₂O)₂]·DMF·H₂O}_n (2) (H₂L = (E)-2-((1-hydroxybutan-2-ylimino)methyl)phenol, pa = 3-phenylacrylate, ppda = p-phenylenediacrylate) were synthesized and characterized by x-ray single crystal structure determination Complex 1 is double phenoxo-bridged dinuclear Ni(II) complex, whereas complex 2 is a 1-dimensional polynuclear chain where double phenoxo-bridged dinuclear units are connected through bridging ppda ligands. The variable temperature magnetic behavior of the complexes was studied using the Hamiltonian H = -JS₁S₂, S₁ = S₂ = S_Ni and confirms the presence of an overall antiferromagnetic interaction in both complexes. Good agreement between the exptl. and simulated curves were found using the parameters: g_Ni = 2.15, D_Ni = 4.0 cm^-1 and J_Ni-Ni = -0.60 cm^-1 for 1, and g_Ni = 2.15, D_Ni = 4.8 cm^-1 and J_Ni-Ni = -3 cm^-1 for 2. The interactions of the complexes with CT-DNA were studied using UV-visible absorption and fluorescence spectroscopic methods and both the complexes interact with CT-DNA. The intrinsic binding constants values for interaction with CT-DNA are 3.9(±0.10) × 10⁵ and 3.43(±0.09) × 10⁵ M^-1 for 1 and 2, resp. The interactions of the complexes with bovine serum albumins (BSA) and human serum albumins (HSA) were also studied using electronic absorption and fluorescence spectroscopic techniques and both complexes interact with the serum albumins via a ground state association process.

Polyhedron published new progress about 96-20-8. 96-20-8 belongs to alcohols-buliding-blocks, auxiliary class Amine,Aliphatic hydrocarbon chain,Alcohol, name is 2-Aminobutan-1-ol, and the molecular formula is C4H11NO, Category: alcohols-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Wang, Bang-Jin published the artcileAn enantioselective potentiometric sensor for 2-amino-1-butanol based on chiral porous organic cage CC3-R, Related Products of alcohols-buliding-blocks, the publication is Molecules (2019), 24(3), 420/1-420/9, database is CAplus and MEDLINE.

Porous organic cages (POCs) have attracted extensive attention due to their unique structures and tremendous application potential in numerous areas. In this study, an enantioselective potentiometric sensor composed of a polyvinyl chloride (PVC) membrane electrode modified with CC3-R POC material was used for the recognition of enantiomers of 2-amino-1-butanol. After optimization, the developed sensor exhibited enantioselectivity toward S-2-amino-1-butanol (log KPotS,R = -0.98) with acceptable sensitivity, and a near-Nernstian response of 25.8 ± 0.3 mV/decade within a pH range of 6.0-9.0.

Molecules published new progress about 96-20-8. 96-20-8 belongs to alcohols-buliding-blocks, auxiliary class Amine,Aliphatic hydrocarbon chain,Alcohol, name is 2-Aminobutan-1-ol, and the molecular formula is C9H22OSi, Related Products of alcohols-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Simond, Mickael published the artcileExcess Molar Enthalpies of Water + Primary Alkanolamines with a Common N-C-C-O Skeleton, Name: 2-Aminobutan-1-ol, the publication is Journal of Chemical & Engineering Data (2021), 66(11), 4206-4214, database is CAplus.

The excess molar enthalpies of binary mixtures of 2-amino-ethan-1-ol (MEA) and 1-aminopropane-2-ol (MIPA), 2-amino-butan-1-ol (ABU), and 2-amino-2-methyl-propan-1-ol (AMP) with water were measured vs. temperatures from 318.15 to 393.15 K and at a pressure of 0.5 MPa. The Redlich-Kister equation was used to fit the exptl. data and to estimate the molar enthalpies of alkanolamine and water at infinite dilution The effect of the substitution of alkyl groups on the carbon of the hydroxyl function is discussed on the basis of mol. simulation results published on alkanolamines earlier.

Journal of Chemical & Engineering Data published new progress about 96-20-8. 96-20-8 belongs to alcohols-buliding-blocks, auxiliary class Amine,Aliphatic hydrocarbon chain,Alcohol, name is 2-Aminobutan-1-ol, and the molecular formula is C14H14N2O2, Name: 2-Aminobutan-1-ol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Aubineau, Thomas published the artcileA One-Pot Reaction toward the Diastereoselective Synthesis of Substituted Morpholines, SDS of cas: 96-20-8, the publication is Organic Letters (2018), 20(23), 7419-7423, database is CAplus and MEDLINE.

The diastereoselective synthesis of various substituted morpholines has been achieved from vinyloxiranes and amino-alcs. under sequential Pd(0)-catalyzed Tsuji-Trost/Fe(III)-catalyzed heterocyclization. Using the same strategy, 2,6-, 2,5-, and 2,3-disubstituted as well as 2,5,6- and 2,3,5-trisubstituted morpholines were obtained in good to excellent yields and diastereoselectivities.

Organic Letters published new progress about 96-20-8. 96-20-8 belongs to alcohols-buliding-blocks, auxiliary class Amine,Aliphatic hydrocarbon chain,Alcohol, name is 2-Aminobutan-1-ol, and the molecular formula is C4H11NO, SDS of cas: 96-20-8.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Delgado, Jose A. C. published the artcileBiocompatible photoinduced alkylation of dehydroalanine for the synthesis of unnatural α-amino acids, Category: alcohols-buliding-blocks, the publication is Organic Letters (2021), 23(13), 5251-5255, database is CAplus and MEDLINE.

A site-selective alkylation of dehydroalanine to access protected unnatural amino acids is described. The protocol is characterized by the wide nature of alkyl radicals employed, mild conditions, and functional group compatibility. This protocol is further extended to access peptides, late-stage functionalization of pharmaceuticals, and enantioenriched amino acids.

Organic Letters published new progress about 96-20-8. 96-20-8 belongs to alcohols-buliding-blocks, auxiliary class Amine,Aliphatic hydrocarbon chain,Alcohol, name is 2-Aminobutan-1-ol, and the molecular formula is C4H11NO, Category: alcohols-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Zema, Zelalem Anja published the artcileTuning the CO₂ absorption and physicochemical properties of K⁺ chelated dual functional ionic liquids by changing the structure of primary alkanolamine ligands, Application of 2-Aminobutan-1-ol, the publication is Journal of Molecular Liquids (2021), 117983, database is CAplus.

To reveal the effects of the alkyl substitutions at alpha (α) or beta (β) position adjacent to amino group of primary alkanolamine ligands on CO₂ absorption and physicochem. properties of metal chelated dual functional ionic liquids (DFILs), four DFILs were prepared by reacting potassium imidazole salt (KIm) with alkanolamine ligands, including 2-amino-2-methyl-1-propanol (AMP), 2-amino-1-butanol (AMB), DL-1-amino-2-propanol (DLAMP), and monoethanolamine (MEA). CO₂ absorption behavior and mechanism of DFILs were studied, and d. (ρ), speed of sound (u), and viscosity (η) of DFILs were measured to correlate with the CO₂ absorption performance. DFT calculations were employed to explore the influence of the interactions between K⁺ and alkanolamine on the CO₂ absorption and physicochem. properties of DFILs. The results show that CO₂ capacity at 333.2 K is as follows: [K(AMP)₂][Im] > [K(AMB)₂][Im] > [K(DLAMP)₂][Im] > [K(MEA)₂][Im], indicating that the introduction of alkyl group at α or β position of alkanolamines can enhance CO₂ capacity, and the effect of the α position is more significant than the β position. Both ρ and u follow the order: [K(AMP)₂][Im] < [K(AMB)₂][Im] < [K(DLAMP)₂][Im] < [K(MEA)₂][Im], while η is in the reverse order. Moreover, the saturated CO₂ capacity of DFILs has an approx. linear relation with the thermal expansion coefficient DFT calculations show that the presence of the alkyl group at α or β position of alkanolamines reduces the Mulliken charge of N and O atom, thereby weakening the cation coordination interaction between K⁺ with ligand, resulting in the decrease in ρ and u of DFILs. Moreover, the decrease in the Mulliken charge of N and O atom in alkanolamine leads to the increase of chelated cation-[Im]^– interaction, thereby increasing η of DFILs. Consequently, [K(AMP)₂][Im] exhibits higher CO₂ capacity and good reversibility, due to the fact that CO₂ can react with the chelated cation and [Im]^– simultaneously. The present study provides a new method for effectively regulating the performance of DFILs.

Journal of Molecular Liquids published new progress about 96-20-8. 96-20-8 belongs to alcohols-buliding-blocks, auxiliary class Amine,Aliphatic hydrocarbon chain,Alcohol, name is 2-Aminobutan-1-ol, and the molecular formula is C13H15NO6S, Application of 2-Aminobutan-1-ol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts