Category: 89466-08-0

《A new FRET probe for ratiometric fluorescence detecting mitochondria-localized drug activation and imaging endogenous hydroxyl radicals in zebrafish》 was written by Deng, Tao; Wang, Xiaojuan; Wu, Shengjun; Hu, Shiyou; Liu, Wei; Chen, Tongkai; Yu, Zhiqiang; Xu, Qin; Liu, Fang. Computed Properties of C6H7BO3 And the article was included in Chemical Communications (Cambridge, United Kingdom) in 2020. The article conveys some information:

A new FRET probe has been prepared for ratiometric fluorescence detection of hydroxyl radicals. It has been successfully used for detecting mitochondria-localized drug activation in living cells and imaging endogenous hydroxyl radicals in zebrafish gastrointestinal (GI) tracts under normal culturing conditions. The results came from multiple reactions, including the reaction of 2-Hydroxyphenylboronic acid(cas: 89466-08-0Computed Properties of C6H7BO3)

2-Hydroxyphenylboronic acid(cas: 89466-08-0) belongs to acyl phenylboronic acid. Phenylboronic acid (PBA) has been used to extract β-blockers (a class of aminoalcohol-containing drugs) from aqueous solution, rat, and human plasma. Computed Properties of C6H7BO3

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

《The Cascade C-H functionalization with sequential hydroxylation and oxidation through heterogeneous BINAP-copper on hydrotalcite》 was written by Zhang, Qiaohong; Wang, Huibin; Hu, Wenkang; Xu, Xiaqing; Xu, Zhaojun; Chen, Chen; Wang, Dawei. Application of 89466-08-0 And the article was included in Journal of Chemical Technology and Biotechnology in 2020. The article conveys some information:

A cascade C-H hydroxylation and further oxidation process, 2-sulfanylphenols 6-OH-R1C6H3S(R2 C6H4) (R1 = H, 2-Br, 3-Br, 4-CF3, etc.; R2 = H, 2-OMe, 3-OMe, 4-F, etc.) and arylthioquinones I (R3 = H, 2,6-Cl2, 3-Br, 4-tBu, etc.) use the heterogeneous catalyst [Cu(binap)I]2@HT. The catalytic system was tolerant to various substituents including alkyl, alkoxy, ester, halogen or trifluoromethyl on the Ph ring of the thiophenols R1C6H4SH/3-R4OC6H4SH (R4 = H, Me) or arylboronic acids R5B(OH)2 (R5 = Ph, 4-ethoxyphenyl, 2,6-dichlorophenyl, etc.). In addition to electron-donating groups, the products with strong electron-withdrawing groups, such as Me formylate and trifluoromethyl also were achieved with good yields at 90°C for 12h (68% and 66%, resp.). Repeated experiment results showed that the catalyst could be reused at least five times without obvious decrease in catalytic activity. In the experimental materials used by the author, we found 2-Hydroxyphenylboronic acid(cas: 89466-08-0Application of 89466-08-0)

2-Hydroxyphenylboronic acid(cas: 89466-08-0) belongs to acyl phenylboronic acid. Phenylboronic acid (PBA) has been used to extract β-blockers (a class of aminoalcohol-containing drugs) from aqueous solution, rat, and human plasma. Application of 89466-08-0

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Kondo, Yuto; Kimura, Hiroyuki; Fukumoto, Chiaki; Yagi, Yusuke; Hattori, Yasunao; Kawashima, Hidekazu; Yasui, Hiroyuki published their research in Journal of Labelled Compounds and Radiopharmaceuticals in 2021. The article was titled 《Copper-mediated radioiodination reaction through aryl boronic acid or ester precursor and its application to direct radiolabeling of a cyclic peptide》.COA of Formula: C6H7BO3 The article contains the following contents:

A copper-mediated radioiodination using aryl boronic precursors is attracting attention as a solution to oxidative iododestannylation and nickel-mediated radioiodination drawbacks. The copper-mediated radiolabeling method allows radioiodination at room temperature with stable aryl boronic precursors without preparing complex starting materials or reagents and can be performed in a reaction vessel exposed to air. This method has good potential in radiochem.; however, studies on the scope of copper-mediated radioiodination through boronic precursors are insufficient. In particular, few reports have demonstrated the effect of protecting groups on radiolabeling efficiency. Therefore, the effect of the protecting group of aryl boronic acids on the copper-mediated radioiodination was investigated. In addition, this method, which does not require heating, is expected to be useful for direct radiolabeling of peptides. Thus, we attempted direct radioiodination of c(RGDyk) as an example. The resulting radioiodination method was well tolerated in various substrates and was unaffected by the pinacol ester-type protecting group. Also, c(RGDyk) was labeled with 125I via copper-mediated radioiodination using an aryl boronic acid precursor. The reaction time and yield were improved, compared with the indirect method. Furthermore, the large difference in polarity between the boronic acid precursor and the radiolabeled compound facilitated purification2-Hydroxyphenylboronic acid(cas: 89466-08-0COA of Formula: C6H7BO3) was used in this study.

2-Hydroxyphenylboronic acid(cas: 89466-08-0) belongs to acyl phenylboronic acid. Phenylboronic acid (PBA) has been used to extract β-blockers (a class of aminoalcohol-containing drugs) from aqueous solution, rat, and human plasma. COA of Formula: C6H7BO3

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts