Category: 873-75-6

Electric Literature of C7H7BrOIn 2019 ,《Efficient Synthesis of Quinazolinones by Transition-Metal-Free Direct Aerobic Oxidative Cascade Annulation of Alcohols with o-Aminoarylnitriles》 appeared in ChemSusChem. The author of the article were Wang, Qi; Lv, Miao; Liu, Jianping; Li, Yang; Xu, Qing; Zhang, Xu; Cao, Hongen. The article conveys some information:

A mild and atom-economic method was developed for direct and efficient synthesis of quinazolinones I (R1 = H, 5-Cl, 6-Br, 7-CH3, etc.; R2 = C6H5, naphthalen-2-yl, thiophen-2-yl, etc.) through a transition-metal-free aerobic oxidative cascade annulation reaction of widely available o-aminoarylnitriles R32-H2NC6H3CN (R3 = H, 4-CH3, 5-Br, 6-Cl, etc.) and alcs. R2CH2OH. Air could be employed as an effective oxidant under mild conditions, generating water as the only byproduct. Possibly owing to the ”cesium effect”, the water-soluble base CsOH was found to be crucial in all key steps of the reaction mechanism. Because a wide range of substrates can be used to prepare substituted quinazolinones without contamination by transition-metal residues, this method may be of interest for application in pharmaceutical synthesis. Possible reaction paths were also proposed according to control reactions. In the experiment, the researchers used many compounds, for example, (4-Bromophenyl)methanol(cas: 873-75-6Electric Literature of C7H7BrO)

(4-Bromophenyl)methanol(cas: 873-75-6) undergoes three-component reaction with acetylferrocene and arylboronic acid to give ferrocenyl ketones containing biaryls.Electric Literature of C7H7BrO It is used in the synthesis of amphiphilic, symmetric rod-coil, triblock copolymer of poly(9,9-didodecylfluorene-2,7-diyl) and poly(hydroxyl ethyl methacrylate)

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

《Selective Activation of Benzyl Alcohol Coupled with Photoelectrochemical Water Oxidation via a Radical Relay Strategy》 was published in ACS Catalysis in 2020. These research results belong to Luo, Lan; Wang, Zhou-jun; Xiang, Xu; Yan, Dongpeng; Ye, Jinhua. Category: alcohols-buliding-blocks The article mentions the following:

Selective oxidation to produce target chems. usually need activation of O2 at high temperature and/or pressure, which have largely restricted its practical operation and application. Here, we put forward a radical-relay strategy coupling photoelectrochem. (PEC) water oxidation towards efficiently selective conversion of benzyl alc. (BA) to benzaldehyde (BAD). An illuminated BiVO4 (BVO) photoanode covered with an ultrathin (∼3 nm) hydrothermally synthesized layered double hydroxide (U-LDH) catalyst and graphene (G) exhibited >99% selectivity to BAD (1.2 V vs. RHE). Mechanistic studies and DFT calculation verified that the hydroxyl radicals (•OH) generated from the oxidation of water are bound to the surface of U-LDH through hydrogen-bonding interactions and the energy is lowered. Fourier transform IR spectroscopy showed that BA is adsorbed to the U-LDH catalyst, but BAD is not. Thus, the selectivity is not only favored by the controlled oxidation capacity of •OH radicals, but the desorption of the desired product from the catalyst before further oxidation occurs. This work introduces an alternative PEC way to achieve mild and selective oxidation of BA derivatives based on ternary G@U-LDH@BVO catalysts. The results came from multiple reactions, including the reaction of (4-Bromophenyl)methanol(cas: 873-75-6Category: alcohols-buliding-blocks)

(4-Bromophenyl)methanol(cas: 873-75-6) undergoes three-component reaction with acetylferrocene and arylboronic acid to give ferrocenyl ketones containing biaryls.Category: alcohols-buliding-blocks It is used in the synthesis of amphiphilic, symmetric rod-coil, triblock copolymer of poly(9,9-didodecylfluorene-2,7-diyl) and poly(hydroxyl ethyl methacrylate)

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

The author of 《Iridium-catalyzed transfer hydrogenation of ketones and aldehydes using glucose as a sustainable hydrogen donor》 were Yoshida, Masato; Hirahata, Ryota; Inoue, Takayoshi; Shimbayashi, Takuya; Fujita, Ken-ichi. And the article was published in Catalysts in 2019. Recommanded Product: 873-75-6 The author mentioned the following in the article:

A new catalytic system for transfer hydrogenation of carbonyl compounds using glucose as a hydrogen donor was developed. Various ketones and aldehydes were efficiently converted to corresponding alcs. with two equivalent of glucose in the presence of a small amount (0.1 to 1.0 mol%) of iridium catalyst that had a functional ligand. In this catalytic system, transfer hydrogenation reactions proceeded based on the cooperativity of iridium and a functional ligand. It should be noted that environmentally benign water was used as a solvent in the present catalytic system for the reduction of various carbonyl substrates. Furthermore, the reaction scope was extended by using N,N-dimethylacetamide as a reaction solvent. The results came from multiple reactions, including the reaction of (4-Bromophenyl)methanol(cas: 873-75-6Recommanded Product: 873-75-6)

(4-Bromophenyl)methanol(cas: 873-75-6) undergoes three-component reaction with acetylferrocene and arylboronic acid to give ferrocenyl ketones containing biaryls.Recommanded Product: 873-75-6 It undergoes oxidation reaction in the presence of polyvinylpolypyrrolidone-supported hydrogen peroxide, silica sulfuric acid and ammonium bromide to yield 4-bromobenzaldehyde.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Ma, Shuai; Cui, Jing-Wang; Rao, Cai-Hui; Jia, Meng-Ze; Chen, Yun-Rui; Zhang, Jie published their research in Green Chemistry in 2021. The article was titled 《Boosting activity of molecular oxygen by pyridinium-based photocatalysts for metal-free alcohol oxidation》.SDS of cas: 873-75-6 The article contains the following contents:

An eco-friendly and economical approach for the photocatalytic oxidation of organic inter-mediates by air under mild conditions is highly desirable in green and sustainable chem., where the photogeneration of active oxygen species plays a key role in improving conversion efficiency and selectivity. By using pyridinium derivatives as mol. mediators for electron transfer and energy transfer, the simultaneous activation of O2 from air into superoxide radicals and singlet oxygen species can be achieved, and a photoinduced electron transfer catalytic system for the oxidation of alcs. has been developed. Thus, we have successfully simplified the complicated catalytic system into a single mol. catalyst without any addnl. noble metals and co-catalysts/additives. The current photocatalytic system shows high catalytic efficiency not only for aromatic alcs. but also for aliphatic alcs. that are generally difficult to undergo aerobic oxidation at room temperature under air atm., representing an ideal photocatalytic platform for green and economical organic syntheses. In the experiment, the researchers used many compounds, for example, (4-Bromophenyl)methanol(cas: 873-75-6SDS of cas: 873-75-6)

(4-Bromophenyl)methanol(cas: 873-75-6) undergoes three-component reaction with acetylferrocene and arylboronic acid to give ferrocenyl ketones containing biaryls.SDS of cas: 873-75-6 It is used in the synthesis of amphiphilic, symmetric rod-coil, triblock copolymer of poly(9,9-didodecylfluorene-2,7-diyl) and poly(hydroxyl ethyl methacrylate)

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

《A Zirconium Indazole Carboxylate Coordination Polymer as an Efficient Catalyst for Dehydrogenation-Cyclization and Oxidative Coupling Reactions》 was written by Sang, Xinxin; Hu, Xinyu; Tao, Rong; Zhang, Yilin; Zhu, Haiyan; Wang, Dawei. Category: alcohols-buliding-blocksThis research focused onzirconium indazole carboxylate coordination polymer catalyst preparation; disubstituted benzimidazole preparation; phenylenediamine benzyl alc dehydrogenative cyclization zirconium catalyst; alkyl ester preparation; benzyl cyanide alkyl hydroperoxide oxidative coupling zirconium catalyst. The article conveys some information:

A novel porous zirconium coordination polymer (Zr-IDA) from 1-(carboxymethyl)-1H-indazole-5-carboxylic acid was developed and characterized. The Zr-IDA catalyst contains porous and highly crystalline particles with a quasi-spherical morphol. around 100 nm in size and Zr was coordinated with both O and N as shown by FT-IR and XPS measurements. The catalyst showed good catalytic activity in the synthesis of 1,2-disubstituted-benzimidazoles I [R = Ph, 4-MeC6H4, 2-thienyl, etc.; R1 = H, Me] via dehydrogenative cyclization reaction of benzyl alcs. with phenylenediamines. Similarly, alkyl-esters R2C(O)OC(CH3)2R3 [R2 = Ph, 4-MeC6H4, 2-naphthyl, etc.; R3 = Me, Et, Ph] were synthesized via oxidative coupling of benzyl cyanides with alkyl-hydroperoxides. Mechanistic investigations were carried out to study these reactions and the developed catalytic system in more detail.(4-Bromophenyl)methanol(cas: 873-75-6Category: alcohols-buliding-blocks) was used in this study.

(4-Bromophenyl)methanol(cas: 873-75-6) undergoes three-component reaction with acetylferrocene and arylboronic acid to give ferrocenyl ketones containing biaryls.Category: alcohols-buliding-blocks It undergoes oxidation reaction in the presence of polyvinylpolypyrrolidone-supported hydrogen peroxide, silica sulfuric acid and ammonium bromide to yield 4-bromobenzaldehyde.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

In 2019,Green Chemistry included an article by Wei, Zheyu; Ru, Shi; Zhao, Qixin; Yu, Han; Zhang, Gang; Wei, Yongge. Category: alcohols-buliding-blocks. The article was titled 《Highly efficient and practical aerobic oxidation of alcohols by inorganic-ligand supported copper catalysis》. The information in the text is summarized as follows:

The oxidation of alcs. to aldehydes or ketones is a highly relevant conversion for the pharmaceutical and fine-chem. industries, and for biomass conversion, and is commonly performed using stoichiometric amounts of highly hazardous oxidants. The aerobic oxidation of alcs. with transition metal complex catalysts previously required complicated organic ligands and/or nitroxyl radicals as co-catalysts. Herein, we report an efficient and eco-friendly method to promote the aerobic oxidation of alcs. using an inorganic-ligand supported copper catalyst 1, (NH4)4[CuMo6O18(OH)6], with O2 (1 atm) as the sole oxidant. Catalyst 1 is synthesized directly from cheap and commonly available (NH4)6Mo7O24·4H2O and CuSO4, which consists of a pure inorganic framework built from a central CuII core supported by six MoVIO6 inorganic scaffolds. The copper catalyst 1 exhibits excellent selectivity and activity towards a wide range of substrates in the catalytic oxidation of alcs., and can avoid the use of toxic oxidants, nitroxyl radicals, and potentially air/moisture sensitive and complicated organic ligands that are not com. available. Owing to its robust inorganic framework, catalyst 1 shows good stability and reusability, and the catalytic oxidation of alcs. with catalyst 1 could be readily scaled up to gram scale with little loss of catalytic activity, demonstrating great potential of the inorganic-ligand supported Cu catalysts in catalytic chem. transformations. The experimental process involved the reaction of (4-Bromophenyl)methanol(cas: 873-75-6Category: alcohols-buliding-blocks)

(4-Bromophenyl)methanol(cas: 873-75-6) undergoes three-component reaction with acetylferrocene and arylboronic acid to give ferrocenyl ketones containing biaryls.Category: alcohols-buliding-blocks It undergoes efficient trimethylsilylation reaction with 1,1,1,3,3,3-hexamethyldisilazane in the presence of catalytic amount of aspartic acid in acetonitrile.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

《Highly efficient oxidation of alcohols to carboxylic acids using a polyoxometalate-supported chromium(III) catalyst and CO2》 was published in Green Chemistry in 2020. These research results belong to Wang, Ying; Wu, ZhiKang; Yu, Han; Han, Sheng; Wei, Yongge. Recommanded Product: (4-Bromophenyl)methanol The article mentions the following:

Direct catalytic oxidation of alcs. to carboxylic acids is very attractive, but economical catalysis systems have not yet been well established. Here, we show that a pure inorganic ligand-supported chromium compound, (NH4)3[CrMo6O18(OH)6] (simplified as CrMo6), could be used to effectively promote this type of reaction in the presence of CO2. In almost all cases, oxidation of various alcs. (aromatic and aliphatic) could be achieved under mild conditions, and the corresponding carboxylic acids can be achieved in high yield. The chromium catalyst 1 can be reused several times with little loss of activity. Mechanism study and control reactions demonstrate that the acidification proceeds via the key oxidative immediate of aldehydes. In the part of experimental materials, we found many familiar compounds, such as (4-Bromophenyl)methanol(cas: 873-75-6Recommanded Product: (4-Bromophenyl)methanol)

(4-Bromophenyl)methanol(cas: 873-75-6) undergoes three-component reaction with acetylferrocene and arylboronic acid to give ferrocenyl ketones containing biaryls.Recommanded Product: (4-Bromophenyl)methanol It undergoes efficient trimethylsilylation reaction with 1,1,1,3,3,3-hexamethyldisilazane in the presence of catalytic amount of aspartic acid in acetonitrile.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Li, Huaifeng; Lupp, Daniel; Das, Pradip K.; Yang, Li; Goncalves, Theo P.; Huang, Mei-Hui; El Hajoui, Marwa; Liang, Lan-Chang; Huang, Kuo-Wei published their research in ACS Catalysis in 2021. The article was titled 《Redox-Neutral Imination of Alcohol with Azide: A Sustainable Alternative to the Staudinger/Aza-Wittig Reaction》.Application of 873-75-6 The article contains the following contents:

Here, a redox-neutral azide-alc. imination methodol. enabled by a base-metal nickel PN3 pincer catalyst were reported. The one-step, waste-free and high atom-economical features highlight its advantages further. Moreover, mechanistic insight suggested a non-metal-ligand cooperation pathway based on the observation of an intermediate and d. functional theory calculations In addition to this study using (4-Bromophenyl)methanol, there are many other studies that have used (4-Bromophenyl)methanol(cas: 873-75-6Application of 873-75-6) was used in this study.

(4-Bromophenyl)methanol(cas: 873-75-6) undergoes three-component reaction with acetylferrocene and arylboronic acid to give ferrocenyl ketones containing biaryls.Application of 873-75-6 It undergoes oxidation reaction in the presence of polyvinylpolypyrrolidone-supported hydrogen peroxide, silica sulfuric acid and ammonium bromide to yield 4-bromobenzaldehyde.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

《Sustainable and Selective Alkylation of Deactivated Secondary Alcohols to Ketones by Non-bifunctional Pincer N-heterocyclic Carbene Manganese》 was written by Lan, Xiao-Bing; Ye, Zongren; Liu, Jiahao; Huang, Ming; Shao, Youxiang; Cai, Xiang; Liu, Yan; Ke, Zhuofeng. Formula: C7H7BrO And the article was included in ChemSusChem in 2020. The article conveys some information:

A sustainable and green route to access diverse functionalized ketones RC(O)CH2CH2R1 (R = Ph, thiophen-2-yl, 4-bromophenyl, etc.; R1 = Ph, naphthalen-2-yl, pyridin-3-yl, etc.) via dehydrogenative-dehydrative cross-coupling of primary R1CH2OH and secondary alcs. RCH(OH)CH3 is demonstrated. This borrowing hydrogen approach employing a pincer N-heterocyclic carbene Mn complex I•Br- (R2 = Me, iPr, Ph) displays high activity and selectivity. A variety of primary and secondary alcs. is well tolerant and results in satisfactory isolated yields. Mechanistic studies suggest that this reaction proceeds via a direct outer-sphere mechanism and the dehydrogenation of the secondary alc. substrates plays a vital role in the rate-limiting step. The results came from multiple reactions, including the reaction of (4-Bromophenyl)methanol(cas: 873-75-6Formula: C7H7BrO)

(4-Bromophenyl)methanol(cas: 873-75-6) undergoes three-component reaction with acetylferrocene and arylboronic acid to give ferrocenyl ketones containing biaryls.Formula: C7H7BrO It undergoes oxidation reaction in the presence of polyvinylpolypyrrolidone-supported hydrogen peroxide, silica sulfuric acid and ammonium bromide to yield 4-bromobenzaldehyde.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

In 2019,Green Chemistry included an article by Huang, Ming; Li, Yinwu; Liu, Jiahao; Lan, Xiao-Bing; Liu, Yan; Zhao, Cunyuan; Ke, Zhuofeng. HPLC of Formula: 873-75-6. The article was titled 《A bifunctional strategy for N-heterocyclic carbene-stabilized iridium complex-catalyzed N-alkylation of amines with alcohols in aqueous media》. The information in the text is summarized as follows:

Through the strategy of combining bifunctional 2-hydroxypyridine and a thermally stable N-heterocyclic carbene ligand, an Ir-catalyzed N-monoalkylation reaction has been developed in aqueous media under base-free conditions. This reaction proceeds smoothly with high yields of various aromatic amines and sulfonamides with a wide range of primary alcs. Exptl. and computational studies revealed a metal-ligand cooperative mechanism and its thermal stability during the bifunctional catalysis in aqueous media. In the experiment, the researchers used (4-Bromophenyl)methanol(cas: 873-75-6HPLC of Formula: 873-75-6)

(4-Bromophenyl)methanol(cas: 873-75-6) undergoes three-component reaction with acetylferrocene and arylboronic acid to give ferrocenyl ketones containing biaryls.HPLC of Formula: 873-75-6 It is used in the synthesis of amphiphilic, symmetric rod-coil, triblock copolymer of poly(9,9-didodecylfluorene-2,7-diyl) and poly(hydroxyl ethyl methacrylate)

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts