Category: 87-73-0

Wang, Ji-Sheng; Feng, Jun-Long; Dai, Heng-Heng; Chen, Zi-Long; Li, Xiao; Bao, Bing-Hao; Deng, Sheng; Meng, Fan-Chao; Zhao, Qi; Xu, Hong-Sheng; Wang, Bin; Li, Hai-Song published the artcile< Potential mechanism of Achyranthis bidentatae radix plus semen vaccariae granules in the treatment of diabetes mellitus-induced erectile dysfunction in rats utilizing combined experimental model and network pharmacology>, Computed Properties of 87-73-0, the main research area is Achyranthis bidentatae semen vaccariae granule DMED treatment network pharmacol; Endocrine diseases; biological network; penis; traditional Chinese medicine.

Achyranthes bidentata Blume (Amaranthaceae) (ABR) and semen vaccariae (SV) are used commonly in the clin. treatment of erectile dysfunction in males with diabetes mellitus (DMED) to strengthen the kidney and promote blood circulation, and often achieve good curative effects. Explore mechanistic details of ABR + SV treatment against DMED. Prediction of key targets by network pharmacol. A rat model of DM was established by streptozotocin injection (55 mg/kg). Apomorphine (100μg/kg) was injected into rats to screen the DMED model. Group C (n = 6) and group M (n = 6) were gavaged with deionized water; group T (n = 6) was given Achyranthis bidentatae radix-semen vaccariae granule suspension (2.5 g/kg). It lasted 8 wk. Real-time reverse transcription-quant. polymerase chain reaction (RT-qPCR) and western blotting (WB) were used to measure the expression of tissue-related proteins and mRNA. The predicted key targets are albumin (ALB), caspase-3 (CASP3), vascular endothelial growth factor A (VEGFA), angiotensin-converting enzyme (ACE), and endothelial nitric oxide synthase (eNOS). Compared with the M group (0.52 ± 0.04; 0.50 ± 0.03; 0.49 ± 0.02; 0.23 ± 0.03), CASP3, VEGFA, and ACE protein expression reduced in the T group (0.39 ± 0.06; 0.34 ± 0.03; 0.39 ± 0.03), and eNOS protein expression increased (0.34 ± 0.03). ABR + SV can improve erectile function in DMED rats. This study provides a potential mechanism for the treatment of DMED with ABR + SV and can benefit from more patients.

Pharmaceutical Biology (Abingdon, United Kingdom) published new progress about Achyranthes bidentata. 87-73-0 belongs to class alcohols-buliding-blocks, and the molecular formula is C6H10O8, Computed Properties of 87-73-0.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Bennouna, Djawed; Tourniaire, Franck; Durand, Thierry; Galano, Jean-Marie; Fine, Frederic; Fraser, Karl; Benatia, Sheherazade; Rosique, Clement; Pau, Charlotte; Couturier, Charlene; Pontet, Celia; Vigor, Claire; Landrier, Jean-Francois; Martin, Jean-Charles published the artcile< The Brassica napus (oilseed rape) seeds bioactive health effects are modulated by agronomical traits as assessed by a multi-scale omics approach in the metabolically impaired ob-mouse>, SDS of cas: 87-73-0, the main research area is Brassica seed inflammation uridine asparagine mannitol valine; Bioactives; Brassica; Metabolomics; Phytochemicals; Transcriptomics.

Beside oil, oilseed rape (Brassica napus) seeds contains nutritional bioactives such as polyphenols and glucosinolates. However, to date their nutritional properties have been overlooked in the new “”double zero”” breeds. Seed alc. extracts from two B. napus cultivars most contrasting in their phytochem. contents as measured by mass-spectrometry were given to ob-mice. Biol. outcomes including clin. metrics, gut and plasma metabolomes, liver transcriptome and metabolome were compared to ob-mice given a similar broccoli extract (Brassica oleracea).One B. napus extract induced a reduction of the oxidative stress indicated by the decrease of plasma isoprostanoids. This was associated to the regulation of the antioxidant stress defense Nrf2 pathway, to omic oxidative stress functions, metabolic and cell process regulations, and the metabolomics microbiota profile.Extracts of B. napus seeds demonstrated health effects that may be improved by selecting appropriate agronomical traits, highlighting the potential benefits of better utilizing agronomy for improved human and animal nutrition

Food Chemistry: Molecular Sciences published new progress about Antioxidants. 87-73-0 belongs to class alcohols-buliding-blocks, and the molecular formula is C6H10O8, SDS of cas: 87-73-0.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Li, Tingna; Zeng, Hairong; Zeng, Yijia; Zhang, Xiaorui; Ren, Yuanyuan; Gao, Yongxiang; Huang, Qinwan; Tan, Jin published the artcile< Characterization of the bioactive compounds with efficacy against gout in Guizhi Shaoyao Zhimu Decoction by UHPLC-Q-Orbitrap HRMS combined with network pharmacological analysis>, Application In Synthesis of 87-73-0, the main research area is Guizhi Shaoyao Zhimu decoction antiarthritic agent gouty arthritis.

The current study aimed to explore the mechanism of Guizhi Shaoyao Zhimu Decoction in the treatment of gouty arthritis based on the combination of Vanquish Ultra High Performance Liquid Chromatog. Q Exactive IV Pole-electrostatic field orbital trap high resolution mass spectrometer (UHPLC-Q-Orbitrap HRMS) and network pharmacol. Firstly, UHPLC-Q-Orbitrap HRMS was established and applied to separation and identification of the chem. components of GSZD. Then, using network pharmacol. anal. to obtain the potential active components and candidate targets underlying the effect of GSZD on gouty arthritis (GA). Through targeted and untargeted anal., a total of 79 components, including 3 chromones, 26 flavonoids, 10 alkaloids, 10 phenolic acids, 7 nucleosides and nucleobases, and 23 other components, were characterized from GSZD. 11 compounds were considered to potentially key active compounds against GA which may be via interacting with multiple inflammatory factors and multiple inflammatory pathways.

Arabian Journal of Chemistry published new progress about Activator protein 1 Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 87-73-0 belongs to class alcohols-buliding-blocks, and the molecular formula is C6H10O8, Application In Synthesis of 87-73-0.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Divya, Indira S.; Amrutha, Surendran; SeethaLekshmi, Sunil; Varughese, Sunil published the artcile< Molecular salts of quinine: a crystal engineering route to enhance the aqueous solubility>, Category: alcohols-buliding-blocks, the main research area is quinine mol salt crystal engineering aqueous solubility.

The antimalarial drug quinine (QUN) has poor aqueous solubility and belongs to Biopharmaceutical Classification System (BCS) Class-II. We report 12 novel mol. salts of QUN with α,ω-aliphatic dicarboxylic acids and aromatic coformers. The high basicity of QUN and ΔpKa of ~5 make the complexes ionic, and most of them are hydrates. The solid forms showed enhanced aqueous solubility compared to the pristine QUN. The single-crystal and powder X-ray diffraction, thermal, and microscopy data provide structural, compositional, and stability profiles of the salts. The calculated Full Interaction Maps (FIMs) provide statistical insights into the salt formation and high probability of hydration in QUN. Though with prospective torsional freedom, QUN in most complexes adopts a unique conformation; this indicates that the structure class has a higher statistical probability and belongs to a relatively deep potential energy trough in the vast crystal landscape.

CrystEngComm published new progress about Aliphatic dicarboxylic acids Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 87-73-0 belongs to class alcohols-buliding-blocks, and the molecular formula is C6H10O8, Category: alcohols-buliding-blocks.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Wan, Qijuan; Wu, Liqun; Yang, Qiuhua; Lin, Mao; Guo, Songlin published the artcile< First identification and pathogenicity study of Vibrio harveyi isolated from diseased American eel (Anguilla rostrata) cultivated in freshwater>, Name: D-Glucosaccharic acid, the main research area is Anguilla rostrata disease freshwater Vibrio harveyi isolation pathogenicity.

Diseases caused by Vibrio harveyi in marine organisms have been generally reported in aquaculture, but there has been no reported V. harveyi infection in fish cultivated in freshwater. Herein, we isolated 3 strains of V. harveyi from diseased American eels (Anguilla rostrata) cultivated in freshwater and subsequently confirmed the virulence of V. harveyi and the extracellular product (ECP). The three isolates were identified as V. harveyi based on phenotypic features and homol. of 16S rDNA and 3 house-keeping genes (HKGs). Exptl. infection revealed that V. harveyi and ECP were highly pathogenic to American eels, and the median LDs (LD50) were 1.67 x 103 cfu/g and 7.29μg/g body weight, resp. Moreover, our antibiotic susceptibility test showed that V. harveyi was susceptible to 16 of 20 antibiotics using the VITEK system of Merieux. Furthermore, liver and kidney samples were collected for paraffin sectioning, stained with haematoxylin-eosin (H & E) and Periodic Acid-Schiff (PAS). H & E staining results revealed hepatocyte atrophy and necrosis, hepatic intercellular hemorrhage and intrahepatic venous thrombosis, while the kidney was characterized by renal tubular epithelial cell swelling and renal interstitial haematopoietic cell loss. Interestingly, glycogen deposition was more obvious in the kidney compared with the liver after PAS staining. Cultivated eel infected by V. harveyii was reported for the first time, and the results of this study provide a valuable reference for further prevention and control of fish diseases caused by V. harveyi.

Aquaculture Research published new progress about 16S rRNA Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 87-73-0 belongs to class alcohols-buliding-blocks, and the molecular formula is C6H10O8, Name: D-Glucosaccharic acid.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Oh, Woo Taek; Jun, Jin Woo; Giri, Sib Sankar; Yun, Saekil; Kim, Hyoun Joong; Kim, Sang Guen; Kim, Sang Wha; Kang, Jeong Woo; Han, Se Jin; Kwon, Jun; Kim, Ji Hyung; Smits, Theo H. M.; Park, Se Chang published the artcile< Pseudomonas tructae sp. nov., novel species isolated from rainbow trout kidney>, Recommanded Product: D-Glucosaccharic acid, the main research area is phosphatidylethanolamine arginine dihydrolase quinone rainbow trout kidney Pseudomonas; MLSA; Pseudomonas; rainbow trout.

This study describes the biochem. and phylogenetic characteristics of a Gram-neg. strain, SNU WT1T, isolated from rainbow trout kidney. The 16S rRNA gene sequencing indicated that strain SNU WT1T was highly similar to Pseudomonas wadenswilerensis CCOS 864T and closely related to other Pseudomonas putida-related strains. Multilocus sequence anal. of concatenated partial gyrB, rpoB and rpoD sequences revealed that strain SNU WT1T was distinct from P. putida-related strains and formed a sep. clade. The average nucleotide identity and Genome-to-Genome Distance Calculator values were 90.19 and 41.7%with its closest relativeP. wadenswilerensis CCOS 864T ; however, it was phenotypically distinct from CCOS 864T with respect to arginine dihydrolase, glucose fermentation, aesculin hydrolysis and N-acetyl-glucosamine assimilation. The major polar lipid of the strain was phosphatidylethanolamine and the major quinone was Q-9. The genome of strain SNU WT1T had 5 685 196 bp with a G+C content of 61.83 mol%. We describe a novel species of genus Pseudomonas, for which the name Pseudomonas tructae has been proposed, with SNU WT1T (= KCTC 72265 = JCM 33436) as the type strain.

International Journal of Systematic and Evolutionary Microbiology published new progress about GC content. 87-73-0 belongs to class alcohols-buliding-blocks, and the molecular formula is C6H10O8, Recommanded Product: D-Glucosaccharic acid.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Zhu, Shu; Wang, Mengya; Qiang, Zhe; Song, Jianchun; Wang, Yue; Fan, Yuchi; You, Zhengwei; Liao, Yaozu; Zhu, Meifang; Ye, Changhuai published the artcile< Multi-functional and highly conductive textiles with ultra-high durability through 'green' fabrication process>, Computed Properties of 87-73-0, the main research area is green conductive GA chitosan polyamide SWCNT composite coated textile.

Conductive textiles with mech. flexibility, long-term durability and stability under harsh conditions are highly desired for potential applications in wearable electronics and devices. One challenge associated with the development of such materials is their fabrication method, which requires to be low-cost, scalable, and environmental-friendly. Herein, we developed a full “”green”” route to fabricate machine-washable conductive textiles by coating textiles with a novel crosslinked and conductive polymer composite coating, using single-walled carbon nanotubes (SWNTs) and bio-mass derived glucaric acid/chitosan (GA-chitosan) organic salt aqueous solution with dip-coating or spray-coating. The crosslinked SWNTs/GA-chitosan polyamide coatings exhibit a high elec. conductivity of up to 7.4 x 102 S/m and high water/organic solvents resistance. The conductive textiles can achieve an exceptional Joule heating performance driven by moderate voltage and exhibit a high electromagnetic interference shielding efficiency of approx. 30 dB at X-band under optimized formulation. The high adhesive energy between the polymer composite coatings and textile substrates enables the ultra-high durability and stability of textiles, confirmed by mech. deformation, rubbing, and washing tests. This simple and organic solvent-free processing method provides an environmentally friendly, cost-effective fabrication approach, holding great promise for large-scale production of multifunctional conductive wearable textiles for EMI shielding and/or personal heating applications.

Chemical Engineering Journal (Amsterdam, Netherlands) published new progress about Carbon nanotubes (single walled). 87-73-0 belongs to class alcohols-buliding-blocks, and the molecular formula is C6H10O8, Computed Properties of 87-73-0.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Duman, Muhammed; Mulet, Magdalena; Altun, Soner; Saticioglu, Izzet Burcin; Gomila, Margarita; Lalucat, Jorge; Garcia-Valdes, Elena published the artcile< Pseudomonas piscium sp. nov., Pseudomonas pisciculturae sp. nov., Pseudomonas mucoides sp. nov. and Pseudomonas neuropathica sp. nov. isolated from rainbow trout>, Product Details of C6H10O8, the main research area is Pseudomonas species isolation rainbow trout; Pseudomonas; aquaculture; genome analysis; multi-locus sequence analysis; rainbow trout.

Six Gram neg., motile bacteria were isolated from rainbow trout (Oncorhynchus mykiss). The 16S rRNA sequence similarity values grouped them in the Pseudomonas mandelii (strains P49, P50T, 154aT and P154b), Pseudomonas fluorescens (strain P115T) and Pseudomonas koreensis (strain P155T) phylogenetic subgroups in the genus Pseudomonas. The DNA G + C content ranged from 58.5 to 60 mol%. The strains were characterized phenotypically using API 20NE and Biolog GENIII tests, and chemotaxonomically by their whole-cell MALDI-TOF MS protein profiles and fatty acid contents. Multi-locus sequence anal. with four housekeeping gene sequences (rpoD, rpoB, gyrB and 16S rRNA) together with genome comparisons by average nucleotide identity and genome-to-genome distance calculations were performed. Results showed that the similarity values of these strains to known species type strains were lower than the thresholds established for species in the genus Pseudomonas. Based on these data, we concluded that strains P49, P50T, P115T, P154aT, P154b and P155T belonged to four novel species. The names proposed are: Pseudomonas piscium sp. nov. for strains P49 and P50T with P50T (= CECT 30175T = CCUG 74871T) as the type strain; Pseudomonas pisciculturae sp. nov. for strain P115T (CECT 30173T = CCUG 74873T); Pseudomonas mucoides sp. nov. for strains P154aT and P154b with P154aT (= CECT 30177T = CCUG 74874T) as the type strain; and Pseudomonas neuropathica sp. nov. for strain P155T (= CECT 30178T = CCUG 74875T).

International Journal of Systematic and Evolutionary Microbiology published new progress about 16S rRNA Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 87-73-0 belongs to class alcohols-buliding-blocks, and the molecular formula is C6H10O8, Product Details of C6H10O8.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Sandu, Mariya P.; Sidelnikov, Vladimir S.; Geraskin, Andrej A.; Chernyavskii, Aleksandr V.; Kurzina, Irina A. published the artcile< Influence of the method of preparation of the Pd-Bi/Al2O3 catalyst on catalytic properties in the reaction of liquid-phase oxidation of glucose into gluconic acid>, Related Products of 87-73-0, the main research area is palladium bismuth alumina catalyst liquid oxidation glucose gluconic acid.

Gluconic acid and its derivatives are extensively used in pharmaceutical, food, textile, and pulp and paper branches of industry during production of food additives, cleansers, medicinal drugs, stabilizers, etc. To obtain gluconic acid, the method of conversion of glucose into gluconic acid by mol. oxygen in the presence of solid catalysts is promising. The process of obtaining Pd and bimetallic nanoparticles Pd-Bi, coated on Al2O3, has been considered in the work. Samples were prepared by combined and successive impregnation of the Al2O3 support using metalloorg. precursors Pd(acac)2, Bi(ac)3, and dissolved in an organic solvent (acetic acid), followed by the removal of excess solvent. To achieve the formation of Pd and bimetallic nanoparticles Pd-Bi on the substrate surface, the synthesized samples were subjected to thermal decomposition sequentially in the atm. of Ar, O2, and H2. The surface of the obtained catalysts was studied by a combination of physicochem. methods of anal. The catalysts were analyzed in the reaction of liquid phase oxidation of glucose. The best results are achieved in the presence of the catalyst obtained by combined impregnation.

Catalysts published new progress about Binding energy. 87-73-0 belongs to class alcohols-buliding-blocks, and the molecular formula is C6H10O8, Related Products of 87-73-0.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Leskow, Carla Coluccio; Conte, Mariana; del Pozo, Talia; Bermudez, Luisa; Lira, Bruno Silvestre; Gramegna, Giovanna; Baroli, Irene; Burgos, Estanislao; Zavallo, Diego; Kamenetzky, Laura; Asis, Ramon; Gonzalez, Mauricio; Fernie, Alisdair Robert; Rossi, Magdalena; Osorio, Sonia; Carrari, Fernando published the artcile< The cytosolic invertase NI6 affects vegetative growth, flowering, fruit set, and yield in tomato>, Formula: C6H10O8, the main research area is Solanum invertase vegetative growth flowering fruit yield; Carbon partitioning; cytosolic invertase; signaling; sucrose metabolism; tomato.

Sucrose metabolism is important for most plants, both as the main source of carbon and via signaling mechanisms that have been proposed for this mol. A cleaving enzyme, invertase (INV) channels sucrose into sink metabolism Although acid soluble and insoluble invertases have been largely investigated, studies on the role of neutral invertases (A/N-INV) have lagged behind. Here, we identified a tomato A/N-INV encoding gene (NI6) co-localizing with a previously reported quant. trait locus (QTL) largely affecting primary carbon metabolism in tomato. Of the eight A/N-INV genes identified in the tomato genome, NI6 mRNA is present in all organs, but its expression was higher in sink tissues (mainly roots and fruits). A NI6-GFP fusion protein localized to the cytosol of mesophyll cells. Tomato NI6-silenced plants showed impaired growth phenotype, delayed flowering and a dramatic reduction in fruit set. Global gene expression and metabolite profile analyses of these plants revealed that NI6 is not only essential for sugar metabolism, but also plays a signaling role in stress adaptation. We also identified major hubs, whose expression patterns were greatly affected by NI6 silencing; these hubs were within the signaling cascade that coordinates carbohydrate metabolism with growth and development in tomato.

Journal of Experimental Botany published new progress about Arabidopsis. 87-73-0 belongs to class alcohols-buliding-blocks, and the molecular formula is C6H10O8, Formula: C6H10O8.

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts