Category: 86-48-6

Lubeck, Josephine S. published the artcileSupercritical fluid chromatography for the analysis of oxygenated polycyclic aromatic compounds in unconventional oils, Name: 1-Hydroxy-2-naphthoic acid, the publication is Journal of Chromatography A (2019), 162-172, database is CAplus and MEDLINE.

Unconventional oil feeds can be rich in oxygenated organic compounds that will neg. affect the fuel properties if they are not removed during refining. In this study, supercritical fluid chromatog. (SFC) was utilized for the combined anal. of polycyclic aromatic hydrocarbons (PAHs) and oxygenated polycyclic aromatic compounds (OPACs). One objective was to chromatog. sep. PAHs from OPACs; another to reach a high peak capacity, improved peak shapes and high signal-to-noise ratios (S/N) for OPACs. These objectives were set to establish a non-target anal. method for oxygenated compounds in unconventional oils by SFC hyphenated to a UV detector and a quadrupole time-of-flight mass spectrometer (QTOF-MS) with neg. electrospray ionization (ESI^–). Highest peak capacities were observed with a 2-picolylamine column with methanol as modifier, however, a better resolution and S/N were obtained with ethanol and 0.1% formic acid. The elution order for OPACs on all columns followed mainly the polarity of the analytes: furans < aldehydes ≤ ketones < phenols ≤ carboxylic acids. Best separation between PAHs and OPACs was achieved with the ethylene-bridged silica column. The optimized SFC-UV-ESI^–-QTOF-MS method was tested on a coal tar middle distillate and a pyrolysis oil where a number of homologous series (e.g. hydroxy-naphthalenes and -benzaldehydes) was tentatively identified.

Journal of Chromatography A published new progress about 86-48-6. 86-48-6 belongs to alcohols-buliding-blocks, auxiliary class Organic Pigment,Natural product, name is 1-Hydroxy-2-naphthoic acid, and the molecular formula is C11H8O3, Name: 1-Hydroxy-2-naphthoic acid.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Li, Xia published the artcileBlue light-powered hydroxynaphthoic acid-titanium dioxide photocatalysis for the selective aerobic oxidation of amines, Recommanded Product: 1-Hydroxy-2-naphthoic acid, the publication is Journal of Colloid and Interface Science (2021), 534-543, database is CAplus and MEDLINE.

Solar photocatalysis is the key to resolve many environmental challenges but is usually hard to achieve over a metal oxide semiconductor. Therefore, assembling π-conjugated mols. onto semiconductors becomes an efficient approach to solar conversion via ligand-to-metal charge transfer. Here, a rational design of ligands for titanium dioxide (TiO₂) is presented to produce robust visible light photocatalysts. Three hydroxynaphthoic acids (HNAs) were selected as ligands by extending an extra benzene ring of salicylic acid (SA) at 3,4 or 4,5 or 5,6 positions. These ligands could regulate the performance of TiO₂ in which 2-hydroxy-1-naphthoic acid (2H1NA) endows the best outcome. In detail, blue light-powered cooperative photocatalysis of 2H1NA-TiO₂ with 2,2,6,6-tetramethylpiperidine-1-oxyl (TEMPO, 5 mol%) inaugurates the expeditious formation of imines by oxidation of amines with atm. oxygen (O₂). Interestingly, the increase of the O₂ pressure from 1 atm to 0.4 MPa promoted the selective oxidation of benzylamine but thereafter declined with a further boost to 0.6 MPa. Notably, an electron transfer between the oxidatively quenched 2H1NA-TiO₂ and TEMPO is established, offering a new pathway for environmental applications. This work presents a strategy in designing cutting-edge visible light photocatalysts via altering semiconductors with surface ligands.

Journal of Colloid and Interface Science published new progress about 86-48-6. 86-48-6 belongs to alcohols-buliding-blocks, auxiliary class Organic Pigment,Natural product, name is 1-Hydroxy-2-naphthoic acid, and the molecular formula is C11H8O3, Recommanded Product: 1-Hydroxy-2-naphthoic acid.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Xu, Xingjian published the artcilePotential biodegradation of phenanthrene by isolated halotolerant bacterial strains from petroleum oil polluted soil in Yellow River Delta, Category: alcohols-buliding-blocks, the publication is Science of the Total Environment (2019), 1030-1038, database is CAplus and MEDLINE.

The Yellow River Delta (YRD), being close to Shengli Oilfield, is at high risk for petroleum oil pollution. The aim of this study was to isolate halotolerant phenanthrene (PHE) degrading bacteria for dealing with this contaminates in salinity environment. Two bacterial strains assigned as FM6-1 and FM8-1 were successfully screened from oil contaminated soil in the YRD. Morphol. and mol. anal. suggested that strains FM6-1 and FM8-1 were belonging to Delftia sp. and Achromobacter sp., resp. Bacterial growth of both strains was not dependent on NaCl, however, grew well under extensive NaCl concentration The optimum NaCl concentration for bacterial production of strain FM8-1 was 4% (m/v), whereas for strain FM6-1, growth was not affected within 2.5% NaCl. Both strains could use the tested aromatic hydrocarbons (naphthalene, phenanthrene, fluoranthene and pyrene) and aliphatic hydrocarbons (C12, C16, C20 and C32) as sole carbon source. The optimized biodegradation conditions for strain FM6-1 were pH 7, 28 °C and 2% NaCl, for strain FM8-1 were pH 8, 28 °C and 2.5% NaCl. The highest biodegradation rate of strains FM6-1 and FM8-1 was found at 150 mg/L PHE and 200 mg/L, resp. In addition, strainsFM8-1 showed a superior biodegradation ability to strain FM6-1 at each optimized condition. The PHE biodegradation process by both strains well fitted to first-order kinetic models and the k₁ values were calculated to be 0.1974 and 0.1070 per day. Strain FM6-1 metabolized PHE via a “phthalic acid” route, while strain FM8-1 metabolized PHE through the “naphthalene” route. This project not only obtained two halotolerant petroleum hydrocarbon degraders but also provided a promising remediation approach for solving oil pollutants in salinity environments.

Science of the Total Environment published new progress about 86-48-6. 86-48-6 belongs to alcohols-buliding-blocks, auxiliary class Organic Pigment,Natural product, name is 1-Hydroxy-2-naphthoic acid, and the molecular formula is C13H10O3, Category: alcohols-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Bouchet, Samuel published the artcileExtending Cross Metathesis To Identify Selective HDAC Inhibitors: Synthesis, Biological Activities, and Modeling, Related Products of alcohols-buliding-blocks, the publication is ACS Medicinal Chemistry Letters (2019), 10(6), 863-868, database is CAplus and MEDLINE.

Dissym. cross metathesis of alkenes as a convergent and general synthetic strategy allowed for the preparation of a new small series of human histone deacetylases (HDAC) inhibitors. Alkenes bearing Boc-protected hydroxamic acid and benzamide and trityl-protected thiols were used to provide the zinc binding groups and were reacted with alkenes bearing aromatic cap groups. One compound was identified as a selective HDAC6 inhibitor lead. Addnl. biol. evaluation in cancer cell lines demonstrated its ability to stimulate the expression of the epithelial marker E-cadherin and tumor suppressor genes like SEMA3F and p21, suggesting a potential use of this compound for lung cancer treatment. Mol. docking on all 11 HDAC isoforms was used to rationalize the observed biol. results.

ACS Medicinal Chemistry Letters published new progress about 86-48-6. 86-48-6 belongs to alcohols-buliding-blocks, auxiliary class Organic Pigment,Natural product, name is 1-Hydroxy-2-naphthoic acid, and the molecular formula is C11H8O3, Related Products of alcohols-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Li, Hui published the artcileExtending the π-conjugated molecules on TiO₂ for the selective photocatalytic aerobic oxidation of sulfides triggered by visible light, Product Details of C11H8O3, the publication is Sustainable Energy & Fuels (2021), 5(7), 2127-2135, database is CAplus.

The assembly of a TiO₂ surface with π-conjugated mols. can give rise to an apparent red-shift of its optical absorption band, and subsequently engender ligand-to-metal charge transfer (LMCT) triggered by visible light. However, the application of LMCT remains elusive due to the vulnerability of these π-conjugated mols. at the vicinity of reactive centers. Therefore, extending the π-conjugation of these mols. was envisioned to overcome this bottleneck with the oxidation of sulfides as a probe reaction. With salicylic acid as the starting mol., extending the benzene ring at 5,6 or 3,4 positions with another one afforded 2-hydroxy-1-naphthoic acid and 1-hydroxy-2-naphthoic acid . Compared to salicylic acid, 2-hydroxy-1-naphthoic acid showed a moderate improvement, while 1-hydroxy-2-naphthoic acid caused a significant enhancement for modifying anatase TiO₂ to conduct the selective aerobic oxidation of sulfides triggered by blue light with (2,2,6,6-tetramethylpiperidin-1-yl)oxyl (TEMPO) as a redox mediator. Ultimately, the aerobic oxidation of organic sulfides to corresponding sulfoxides in CH₃OH was achieved by the 1-hydroxy-2-naphthoic acid-TiO₂ photocatalyst in cooperation with TEMPO. This study introduces the assembly of extended π-conjugated mols. on TiO₂, which may pave the way to construct more efficient visible-light photocatalysts.

Sustainable Energy & Fuels published new progress about 86-48-6. 86-48-6 belongs to alcohols-buliding-blocks, auxiliary class Organic Pigment,Natural product, name is 1-Hydroxy-2-naphthoic acid, and the molecular formula is C11H8O3, Product Details of C11H8O3.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Sun, Jie published the artcileA dual probe for selective sensing of Zn (II) by fluorescent and Cu (II) by colorimetric methods in different systems based on 7,8-benzochromone-3-carbaldehyde -(fluorescein)hydrazone, Synthetic Route of 86-48-6, the publication is Journal of Photochemistry and Photobiology, A: Chemistry (2021), 113007, database is CAplus.

In this study, a novel fluorescent probe sensor, 7,8-benzochromone-3-carbaldehyde (fluorescein)hydrazone L, was designed and synthesized. Based on the photoinduced electron transfer (PET) process, L can detect Zn²⁺ in the solution of EtOH/H₂O (9/1, V/V). The probe had high selectivity and sensitivity to Zn²⁺ with a lower detection limit of 3.4 x 10^-7 M. Furthermore, the coordination ratio of L-Zn²⁺ was 1:1, which could be corroborated by Job′s plot. In addition, in the EtOH/ H₂O (5/2, V/V) solution of the probe L, Cu²⁺ was added to produce a marked change in color from achromatous to yellow, indicating that the probe L could detect Cu²⁺ by colorimetry, which was detectable by the naked eye, simply and quickly. According to the Benesi-Hildebrand equation, the complexing constants values of L-Zn²⁺ and L-Cu²⁺ were 9.8 x 104 M²⁺ and 1.009 x 105 M²⁺, resp.

Journal of Photochemistry and Photobiology, A: Chemistry published new progress about 86-48-6. 86-48-6 belongs to alcohols-buliding-blocks, auxiliary class Organic Pigment,Natural product, name is 1-Hydroxy-2-naphthoic acid, and the molecular formula is C6H5F4NO3S, Synthetic Route of 86-48-6.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Smith, Mark G. published the artcileNovel crystal forms of 4-aminoantipyrine and its derivatives: Co-crystallizing a reluctant molecule, Quality Control of 86-48-6, the publication is Journal of Molecular Structure (2019), 307-313, database is CAplus.

To the best of our knowledge, the first co-crystallization of the pharmaceutical ingredient 4-aminoantipyrine is reported with 2-aminobenzoic acid as the co-former, and the method used for its supramol. synthesis is discussed. Two mol. salts of 4-aminoantipyrine, as well as two co-crystals of a derivative of 4-aminoantipyrine were also synthesized. The complexes discussed show that careful application of synthon theory, choice of solvent and consideration of the pK_a difference between 4-aminoantipyrine and the co-former are required to successfully co-crystallize this reactive mol. In summary, the co-former must be chosen so that its functional group forms a robust heterosynthon with the reactive mol. The presence of polar solvents or large pK_a differences between 4-aminoantipyrine and its potential co-crystallizer favors salt formation, whereas a non-polar solvent and a small pK_a difference is required for the co-crystallization of 4-aminoantipyrine.

Journal of Molecular Structure published new progress about 86-48-6. 86-48-6 belongs to alcohols-buliding-blocks, auxiliary class Organic Pigment,Natural product, name is 1-Hydroxy-2-naphthoic acid, and the molecular formula is C18H28N2O7, Quality Control of 86-48-6.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Dishman, Sarah N. published the artcileDivergent stereochemical outcomes in the insertion of donor/donor carbenes into the C-H bonds of stereogenic centers, Computed Properties of 86-48-6, the publication is Chemical Science (2022), 13(4), 1030-1036, database is CAplus and MEDLINE.

Herein, the insertion of donor/donor carbenes into stereogenic carbon centers allowing access to trisubstituted benzodihydrofurans in a single step was reported. This study illuminates, for the first time, the stereochem. impact on the carbene center and delineates the structural factors that enable control over both stereogenic centers. Sterically bulky, highly activated C-H insertion centers exhibit high substrate control yielding a single diastereomer and a single enantiomer of product regardless of the catalyst used. Less bulky, less activated C-H insertion centers exhibit catalyst control over the diastereomeric ratio (dr), where a single enantiomer of each diastereomer was observed with high selectivity. A combination of exptl. studies and DFT calculations was used to elucidate the origin of these results. First, hydride transfer from the stereogenic insertion site proceeds with high stereoselectivity to the carbene center, thus determining the absolute configuration of the product. Second, the short lived zwitterionic intermediate can diastereoselectively ring-close by a hitherto unreported SE2 mechanism that was either controlled by the substrate or the catalyst. These results demonstrate that donor/donor carbenes undergo uniquely stereoselective reactions that originate from a stepwise reaction mechanism, in contrast to the analogous concerted reactions of carbenes with one or more electron-withdrawing groups attached.

Chemical Science published new progress about 86-48-6. 86-48-6 belongs to alcohols-buliding-blocks, auxiliary class Organic Pigment,Natural product, name is 1-Hydroxy-2-naphthoic acid, and the molecular formula is C11H8O3, Computed Properties of 86-48-6.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Smith, Mark G. published the artcileNovel crystal forms of 4-aminoantipyrine and its derivatives: Co-crystallizing a reluctant molecule, Quality Control of 86-48-6, the publication is Journal of Molecular Structure (2019), 307-313, database is CAplus.

To the best of our knowledge, the first co-crystallization of the pharmaceutical ingredient 4-aminoantipyrine is reported with 2-aminobenzoic acid as the co-former, and the method used for its supramol. synthesis is discussed. Two mol. salts of 4-aminoantipyrine, as well as two co-crystals of a derivative of 4-aminoantipyrine were also synthesized. The complexes discussed show that careful application of synthon theory, choice of solvent and consideration of the pK_a difference between 4-aminoantipyrine and the co-former are required to successfully co-crystallize this reactive mol. In summary, the co-former must be chosen so that its functional group forms a robust heterosynthon with the reactive mol. The presence of polar solvents or large pK_a differences between 4-aminoantipyrine and its potential co-crystallizer favors salt formation, whereas a non-polar solvent and a small pK_a difference is required for the co-crystallization of 4-aminoantipyrine.

Journal of Molecular Structure published new progress about 86-48-6. 86-48-6 belongs to alcohols-buliding-blocks, auxiliary class Organic Pigment,Natural product, name is 1-Hydroxy-2-naphthoic acid, and the molecular formula is C18H28N2O7, Quality Control of 86-48-6.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Dishman, Sarah N. published the artcileDivergent stereochemical outcomes in the insertion of donor/donor carbenes into the C-H bonds of stereogenic centers, Computed Properties of 86-48-6, the publication is Chemical Science (2022), 13(4), 1030-1036, database is CAplus and MEDLINE.

Herein, the insertion of donor/donor carbenes into stereogenic carbon centers allowing access to trisubstituted benzodihydrofurans in a single step was reported. This study illuminates, for the first time, the stereochem. impact on the carbene center and delineates the structural factors that enable control over both stereogenic centers. Sterically bulky, highly activated C-H insertion centers exhibit high substrate control yielding a single diastereomer and a single enantiomer of product regardless of the catalyst used. Less bulky, less activated C-H insertion centers exhibit catalyst control over the diastereomeric ratio (dr), where a single enantiomer of each diastereomer was observed with high selectivity. A combination of exptl. studies and DFT calculations was used to elucidate the origin of these results. First, hydride transfer from the stereogenic insertion site proceeds with high stereoselectivity to the carbene center, thus determining the absolute configuration of the product. Second, the short lived zwitterionic intermediate can diastereoselectively ring-close by a hitherto unreported SE2 mechanism that was either controlled by the substrate or the catalyst. These results demonstrate that donor/donor carbenes undergo uniquely stereoselective reactions that originate from a stepwise reaction mechanism, in contrast to the analogous concerted reactions of carbenes with one or more electron-withdrawing groups attached.

Chemical Science published new progress about 86-48-6. 86-48-6 belongs to alcohols-buliding-blocks, auxiliary class Organic Pigment,Natural product, name is 1-Hydroxy-2-naphthoic acid, and the molecular formula is C11H8O3, Computed Properties of 86-48-6.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts