Category: 86-48-6

Maeda, Allyn H. published the artcileChemical and genomic analyses of polycyclic aromatic hydrocarbon biodegradation in Sphingobium barthaii KK22 reveals divergent pathways in soil sphingomonads, Product Details of C11H8O3, the publication is International Biodeterioration & Biodegradation (2020), 104993, database is CAplus.

Polycyclic aromatic hydrocarbons (PAHs) are hazardous pollutants that are biodegraded by soil bacteria and the soil sphingomonads are thought to be major contributors to PAH biodegradation To predict PAH environmental fates it is necessary to understand the chem. and genetics of PAH biodegradation by sphingomonads. When the soil sphingomonad Sphingobium barthaii KK22 was exposed to low mol. weight (LMW) PAHs and biotransformation products were investigated by comprehensive chem. analyses, at least twenty products were identified by different techniques and both intradiol- and extradiol-aromatic ring cleavage pathways were found to be active in this organism. Sphingomonads, a large and diverse group, have been studied in regard to PAH biodegradation, however intradiol-ring cleavage of LMW PAHs has never been reported. Whole genome sequencing and prediction of S. barthaii KK22 functional genes revealed sets of aromatic ring-hydroxylating oxygenases and PAH biotransformation genes. Combined with chem. analyses results, novel, near complete PAH biotransformation pathways for soil sphingomonads were constructed. In conjunction with quant. assays, a comprehensive view of PAH biodegradation was obtained that revealed divergent downstream pathways that advanced our understanding of the PAH biotransformation capabilities of these versatile soil bacteria and shall aid in predictions of PAH environmental fate during soil bioremediation.

International Biodeterioration & Biodegradation published new progress about 86-48-6. 86-48-6 belongs to alcohols-buliding-blocks, auxiliary class Organic Pigment,Natural product, name is 1-Hydroxy-2-naphthoic acid, and the molecular formula is C11H8O3, Product Details of C11H8O3.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Rahaman, Rubina published the artcileDioxygen reactivity of iron(II)-gentisate/1,4-dihydroxy-2-naphthoate complexes of N4 ligands: oxidative coupling of 1,4-dihydroxy-2-naphthoate, Synthetic Route of 86-48-6, the publication is Dalton Transactions (2019), 48(45), 16993-17004, database is CAplus and MEDLINE.

The influence of supporting ligands and co-ligands on the dioxygen reactivity of Fe(II) complexes, [(6-Me₃-TPA)Fe^II(GN-H)]⁺ (1), [(6-Me₃-TPA)Fe^II(DHN-H)]⁺ (1a), [(BPMEN)Fe^II(GN-H)]⁺ (2), [(BPMEN)Fe^II(DHN-H)]⁺ (2a), [(TBimA)Fe^II(GN-H)]⁺ (3), and [(TBimA)Fe^II(DHN-H)]⁺ (3a) (GN-H₂ = 2,5-dihydroxybenzoic acid and DHN-H₂ = 1,4-dihydroxy-2-naphthoic acid) of N4 ligands, is presented. The Fe(II)-gentisate complexes react with dioxygen to afford the corresponding Fe(III) species. On the contrary, DHN-H undergoes oxidative C-C coupling to form [2,2′-binaphthalene]-1,1′,4,4′-tetrone 3-hydroxy-3′-carboxylic acid (BNTHC) on 1a, and [2,2′-binaphthalene]-1,1′,4,4′-tetrone 3,3′-dicarboxylic acid (BNTD) on 2a and 3a. In each case, the reaction proceeds through an Fe(III)-DHN species. The x-ray single crystal structures of [(6-Me₃-TPA)Fe^II(BNTD)] (1^Ox) and [(BPMEN)Fe^II(BNTD)] (2^Ox) confirm the coupling of two DHN-H mols. The formation of Fe(III) product without any coupling of co-ligand from the complexes, [(BPMEN)Fe^II(HNA)]⁺ (2b) and [(BPMEN)Fe^II(5-OMeSA)]⁺ (2c) (HNA = 1-hydroxy-2-naphthoate, 5-OMeSA = 5-methoxysalicylate) confirms the importance of para-hydroxy group for the coupling reaction. The unusual coupling of DHN-H by the Fe(II) complexes of the neutral N4 ligands is distinctly different from the oxygenolytic aromatic C-C cleavage of DHN by the Fe(II) complex of a facial N3 ligand.

Dalton Transactions published new progress about 86-48-6. 86-48-6 belongs to alcohols-buliding-blocks, auxiliary class Organic Pigment,Natural product, name is 1-Hydroxy-2-naphthoic acid, and the molecular formula is C11H8O3, Synthetic Route of 86-48-6.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Suzuki, Yumena published the artcileExploring novel cocrystalline forms of oxyresveratrol to enhance aqueous solubility and permeability across a cell monolayer, COA of Formula: C11H8O3, the publication is Biological & Pharmaceutical Bulletin (2019), 42(6), 1004-1012, database is CAplus and MEDLINE.

Oxyresveratrol (ORV) is a naturally extracted compound with many pharmacol. activities. However, information about the crystalline form is not known when considering the development of a form for oral dosage. Cocrystal engineering offers drug mol. understanding and drug solubility improvements. Thus, we attempted cocrystn. of ORV using 10 carboxylic acids as a coformer at a 1:1 M ratio. Each combination was processed with liquid-assisted grinding, solvent evaporation and a slurry method, then characterized by powder X-ray powder diffraction (PXRD), conventional and low-frequency Raman spectroscopy and thermal anal. The solubility, dissolution and permeation studies across Caco-2 cell monolayers were conducted to evaluate the ORV samples. A screening study revealed that an ORV and citric acid (CTA) cocrystal formed by Et acetate-assisted grinding had characteristic PXRD peaks (14.0 and 16.5°) compared to those of ORV dihydrate used as a starting material. Low-frequency Raman measurements, with peaks at 100 cm^-1, distinguished potential cocrystals among three processing methods while conventional Raman could not. An endothermic melt (142.2°C) confirmed the formation of the novel crystalline complex. The solubility of the cocrystal in the dissolution media of pH 1.2 and 6.8 was approx. 1000μg/mL, a 1.3-fold increase compared to ORV alone. In vitro cytotoxicity studies showed that the cocrystal and phys. blend were not toxic at concentrations of 25 and 12.5μM ORV, resp. The ORV-CTA cocrystal enhanced the cellular transport of ORV across Caco-2 monolayers. Therefore, cocrystn. could be used to improve aqueous solubility and permeability, leading to better oral bioavailability of ORV.

Biological & Pharmaceutical Bulletin published new progress about 86-48-6. 86-48-6 belongs to alcohols-buliding-blocks, auxiliary class Organic Pigment,Natural product, name is 1-Hydroxy-2-naphthoic acid, and the molecular formula is C7H13BrSi, COA of Formula: C11H8O3.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Mallah, Ramnath R. published the artcileNon-linear optical response of meso hybrid BODIPY: Synthesis, photophysical, DFT and Z scan study, COA of Formula: C11H8O3, the publication is Spectrochimica Acta, Part A: Molecular and Biomolecular Spectroscopy (2019), 126-140, database is CAplus and MEDLINE.

Hybrid meso BODIPY dyes are synthesized and their linear and nonlinear optical properties are studied. Time-resolved fluorescence lifetime decay is identical for all dyes irresp. of meso substituents. The Z-scan experiment performed to calculate the nonlinear absorption coefficient (β) and 3rd-order nonlinear susceptibility (χ³). Global hybrid (B3LYP and BHHLYP) and range-separated hybrid (CAM-B3LYP) functional with the basis set 6-311++G(d,p) was employed to determine the theor. linear and nonlinear optical properties. The computed β₀ value of all the 3 dyes is superior to that of urea (βo = 0.371 × 10^-30 esu). Introduction of meso substituent directly affects the polarizability and 2nd-order hyperpolarizability of the dyes. Thermal and reorientational effect of the studied NLOphoric dyes were studied.

Spectrochimica Acta, Part A: Molecular and Biomolecular Spectroscopy published new progress about 86-48-6. 86-48-6 belongs to alcohols-buliding-blocks, auxiliary class Organic Pigment,Natural product, name is 1-Hydroxy-2-naphthoic acid, and the molecular formula is C11H8O3, COA of Formula: C11H8O3.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Ahfad, Neda published the artcileA naphthylamide based fluorescent probe for detection of Al³⁺, Fe³⁺, and CN^– with high sensitivity and selectivity, Product Details of C11H8O3, the publication is Spectrochimica Acta, Part A: Molecular and Biomolecular Spectroscopy (2020), 117753, database is CAplus and MEDLINE.

A naphthylamide based fluorescent chemosensor, N,N′-(1,2-phenylene)bis(1-hydroxy-2-naphthamide) (H₄L), for detection of Fe³⁺ and Al³⁺ cations as well as CN^– anion is reported. This compound has been synthesized by a novel and facile synthetic method with high yield and characterized by FT-IR, ¹H NMR, elemental anal., and UV-Vis spectroscopy. It could detect Fe³⁺ and Al³⁺ ions in different media with different excitation and emission wavelengths. In DMSO solution, H₄L showed selective ON-OFF quenching of its 451 nm emission in the presence of Fe³⁺. On the other hand, in DMF solution, H₄L exhibited selective OFF-ON fluorescence upon the addition of Al³⁺, the intensity at 429 nm increases drastically by 24-fold. Also, among the anions, the probe can selectively distinguish CN^– by deprotonation of OH and NH groups, as proved by ¹H NMR titration TD-DFT calculation supports the UV-Vis and fluorescence measurements of the chemosensor.

Spectrochimica Acta, Part A: Molecular and Biomolecular Spectroscopy published new progress about 86-48-6. 86-48-6 belongs to alcohols-buliding-blocks, auxiliary class Organic Pigment,Natural product, name is 1-Hydroxy-2-naphthoic acid, and the molecular formula is C11H8O3, Product Details of C11H8O3.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Khajavi-Shojaei, Shila published the artcileBiodegradation and phytotoxicity assessment of phenanthrene by biosurfactant-producing Bacillus pumilus 1529 bacteria, Product Details of C11H8O3, the publication is Chemistry and Ecology (2020), 36(5), 396-409, database is CAplus.

Phenanthrene is a toxic and mutagenic pollutant that can cause severe environmental and human health issues. The bioremediation of these polyaromatic hydrocarbons (PAHs) is possible with a biosurfactant by enhancing hydrophobicity. In this study, the production of a biosurfactant by Bacillus pumilus 1529 and its effects on the phenanthrene biodegradation pathway were examined Biosurfactant production was determined using hemolytic activity, emulsification index, and surface tension. For phenanthrene metabolite detection, samples at 0, 7, 14, and 21 incubation days were analyzed by gas chromatog.-mass (GC-mass) spectrometry. The results showed that Bacillus pumilus 1529 can reduce surface tension to 22.83 ± 1.1 mN m-1. Furthermore, the GC-mass spectrometry anal. showed that 1-hydroxy-2-naphthoic acid, benzaldehyde, o-phthalic acid, and phenylacetic acid were notable phenanthrene metabolites produced during phenanthrene biodegradation Biodegraded phenanthrene and its metabolites have a less toxic effect on the germination of safflower seeds than non-biodegraded phenanthrene. The IC50 of phenanthrene on seed germination after biodegradation was increased to approx. 113 mg L-1. In general, biodegradation aided by biosurfactant producing bacteria contributed to turning the toxic phenanthrene into less harmful metabolites with lower phytotoxicity effects, indicating that its application in the bioremediation of PAHs is promising.

Chemistry and Ecology published new progress about 86-48-6. 86-48-6 belongs to alcohols-buliding-blocks, auxiliary class Organic Pigment,Natural product, name is 1-Hydroxy-2-naphthoic acid, and the molecular formula is C11H8O3, Product Details of C11H8O3.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Odoardi, Sara published the artcileMetabolism study and toxicological determination of mephtetramine in biological samples by liquid chromatography coupled with high-resolution mass spectrometry, Recommanded Product: 1-Hydroxy-2-naphthoic acid, the publication is Drug Testing and Analysis (2021), 13(8), 1516-1526, database is CAplus and MEDLINE.

The emerging market of new psychoactive substances (NPSs) is a global-scale phenomenon, and their identification in biol. samples is challenging because of the lack of information about their metabolism and pharmacokinetic. In this study, we performed in silico metabolic pathway prediction and in vivo metabolism experiments, in order to identify the main metabolites of mephtetramine (MTTA), an NPS found in seizures since 2013. MetaSite software was used for in silico metabolism predictions and subsequently the presence of metabolites in the blood, urine, and hair of mice after MTTA administration was verified. The biol. samples were analyzed by liquid chromatog. coupled with high-resolution mass spectrometry (LC-HRMS) using a benchtop Orbitrap instrument. This confirmed the concordance between software prediction and exptl. results in biol. samples. The metabolites were identified by their accurate masses and fragmentation patterns. LC-HRMS anal. identified the dehydrogenated and demethylated-dehydrogenated metabolites, together with unmodified MTTA in the blood samples. Besides unmodified MTTA, 10 main metabolites were detected in urine. In hair samples, only demethyl MTTA was detected along with MTTA. The combination of Metasite prediction and in vivo experiment was a powerful tool for studying MTTA metabolism This approach enabled the development of the anal. method for the detection of MTTA and its main metabolites in biol. samples. The development of anal. methods for the identification of new drugs and their main metabolites is extremely useful for the detection of NPS in biol. specimens. Indeed, high throughput methods are precious to uncover the actual extent of use of NPS and their toxicity.

Drug Testing and Analysis published new progress about 86-48-6. 86-48-6 belongs to alcohols-buliding-blocks, auxiliary class Organic Pigment,Natural product, name is 1-Hydroxy-2-naphthoic acid, and the molecular formula is C11H8O3, Recommanded Product: 1-Hydroxy-2-naphthoic acid.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Tharmalingam, Balamurugan published the artcileNitrogen rich triaminoguanidine-pyrrole conjugate as supramolecular synthon for the construction of charge-assisted hydrogen bonded network with various carboxylic acids, Application of 1-Hydroxy-2-naphthoic acid, the publication is Journal of Solid State Chemistry (2022), 122637, database is CAplus.

In this paper, we report the construction of hydrogen bonded supramol. assemblies of salt obtained from novel nitrogen rich C₃-sym. star-shaped triaminoguanidine-pyrrole conjugate and various carboxylic acids. Different types of supramol. assembly were achieved by using a variety of carboxylate anions. Formation of all compounds were confirmed by single crystal anal. The hydrogen bonded three-dimensional supramol. network assemblies (1-6) are harvested by utilizing traditional N-H···O, O-H···O, and weak C-H···π interactions. Among all salts, heterosynthons R¹₂(10) containing traditional N-H···O interactions are commonly observed The thermal stability of salt 1-6 has been examined by thermogravimetric anal. (TGA).

Journal of Solid State Chemistry published new progress about 86-48-6. 86-48-6 belongs to alcohols-buliding-blocks, auxiliary class Organic Pigment,Natural product, name is 1-Hydroxy-2-naphthoic acid, and the molecular formula is C3H7BrO2S, Application of 1-Hydroxy-2-naphthoic acid.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Zhou, Xin published the artcileSynthesis of 2-oxazolines from ring opening isomerization of 3-amido-2-phenyl azetidines, Product Details of C11H8O3, the publication is Molecules (2021), 26(4), 857, database is CAplus and MEDLINE.

In this paper, an efficient synthesis of 2-oxazolines I (R = Me, Ph, furan-2-yl, 1-hydroxynaphthalen-2-yl, etc.) has been achieved via the stereospecific isomerization of 3-amido-2-Ph azetidines II. The reactions were studied in the presence of both Bronsted and Lewis acids, and Cu(OTf)₂ were found to be the most effective.

Molecules published new progress about 86-48-6. 86-48-6 belongs to alcohols-buliding-blocks, auxiliary class Organic Pigment,Natural product, name is 1-Hydroxy-2-naphthoic acid, and the molecular formula is C2H3N3, Product Details of C11H8O3.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Goswami, Lalit published the artcileBiological treatment of wastewater containing a mixture of polycyclic aromatic hydrocarbons using the oleaginous bacterium Rhodococcus opacus, SDS of cas: 86-48-6, the publication is Journal of Cleaner Production (2018), 1282-1291, database is CAplus.

Polycyclic aromatic hydrocarbons (PAHs), including naphthalene, phenanthrene and fluoranthene are commonly found in wastewaters from refineries and biomass gasification industries. This study investigated the simultaneous biodegradation of these PAHs along with lipid accumulation by Rhodococcus opacus in a ternary substrate system. A 2³ full factorial design of experiments was employed with the three PAHs at two different levels by varying their initial concentrations in the range 50-200 mg L^-1 each. A maximum removal of 91.6%, 82.3% and 80.7% was achieved for naphthalene, phenanthrene and fluoranthene, resp. The individual effect of PAH concentration was found to be more significant than 2-way and 3-way interaction effects on their degradation PAH biodegradation efficiency in the mixture was mainly affected by initial concentration and aromatic complexity of the PAHs. Identification of the PAH degradation metabolites was carried out using LC-MS anal., which clearly revealed that the PAHs were degraded primarily via the ortho/para pathway. This study demonstrates the potential utility of R. opacus for bioremediation and industrial wastewater treatment.

Journal of Cleaner Production published new progress about 86-48-6. 86-48-6 belongs to alcohols-buliding-blocks, auxiliary class Organic Pigment,Natural product, name is 1-Hydroxy-2-naphthoic acid, and the molecular formula is C11H8O3, SDS of cas: 86-48-6.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts