Category: 851615-07-1

Construction of Optically Active Quaternary Propargyl Amines by Highly Enantioselective Zinc/BINOL-Catalyzed Alkynylation of Ketoimines [Erratum to document cited in CA159:576933] was written by Huang, Gaochao;Yin, Zengsheng;Zhang, Xingang. And the article was included in Chemistry – A European Journal in 2013.Reference of 851615-07-1 The following contents are mentioned in the article:

The CCDC numbers reported for compounds 5j, 6j, 7a, and 9 were incorrect; the corrected numbers are given and the supplementary crystallog. data can be obtained from The Cambridge Crystallog. Data Center. This study involved multiple reactions and reactants, such as (R)-[1,3′:1′,1”:3”,1”’-Quaternaphthalene]-2′,2”-diol (cas: 851615-07-1Reference of 851615-07-1).

(R)-[1,3′:1′,1”:3”,1”’-Quaternaphthalene]-2′,2”-diol (cas: 851615-07-1) belongs to alcohols. Under appropriate conditions, inorganic acids also react with alcohols to form esters. To form these esters, a wide variety of specialized reagents and conditions can be used. Alcohols may be oxidized to give ketones, aldehydes, and carboxylic acids. These functional groups are useful for further reactions. Oxidation of organic compounds generally increases the number of bonds from carbon to oxygen (or another electronegative element, such as a halogen), and it may decrease the number of bonds to hydrogen.Reference of 851615-07-1

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Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Highly Acidic BINOL-Derived Phosphoramidimidates and their Application in the Bronsted Acid Catalyzed Synthesis of α-Tocopherol was written by Kaib, Philip S. J.;List, Benjamin. And the article was included in Synlett in 2016.Application of 851615-07-1 The following contents are mentioned in the article:

The design and synthesis of highly acidic BINOL-derived N,N’-bistriflylphosphoramidimidate and N,N’-bisarylsulfonylphosphoramidimidate Bronsted acid catalysts are reported. Thus, freshly prepared phosphoramidimidate I catalyzed the diastereoselective addition of trimethylhydroquinone to (7R,11R)-isophytol to give α-tocopherol with a diastereomeric ratio of 66:34. This study involved multiple reactions and reactants, such as (R)-[1,3′:1′,1”:3”,1”’-Quaternaphthalene]-2′,2”-diol (cas: 851615-07-1Application of 851615-07-1).

(R)-[1,3′:1′,1”:3”,1”’-Quaternaphthalene]-2′,2”-diol (cas: 851615-07-1) belongs to alcohols. A strong base can deprotonate an alcohol to yield an alkoxide ion (R―O−). For example, sodamide (NaNH2), a very strong base, abstracts the hydrogen atom of an alcohol. The most common reactions of alcohols can be classified as oxidation, dehydration, substitution, esterification, and reactions of alkoxides.Application of 851615-07-1

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Novel Axially Chiral Ligand-Enabled Copper-Catalyzed Asymmetric Oxidative Coupling of 2-Naphthols for the Synthesis of 6,6′-Disubstituted BINOLs was written by Wang, Pengyang;Cen, Shouyi;Gao, Jun;Shen, Ahui;Zhang, Zhipeng. And the article was included in Organic Letters in 2022.Computed Properties of C40H26O2 The following contents are mentioned in the article:

Novel axially chiral ligands such as I [R = H, 1-naphthyl, 9-anthryl, etc.] were designed and synthesized by merging the chelating picolinic acid with substituted BINOLs. The in-situ-prepared copper catalysts from the ligands and CuI enable the asym. oxidative coupling of 2-naphthols, affording 6,6′-disubstituted BINOLs such as II [R¹ = H, i-Pr, Ph, etc.] in up to 89% yield with good enantioselectivities (up to 96:4 e.r.). This study involved multiple reactions and reactants, such as (R)-[1,3′:1′,1”:3”,1”’-Quaternaphthalene]-2′,2”-diol (cas: 851615-07-1Computed Properties of C40H26O2).

(R)-[1,3′:1′,1”:3”,1”’-Quaternaphthalene]-2′,2”-diol (cas: 851615-07-1) belongs to alcohols. Similar to water, an alcohol can be pictured as having an sp3 hybridized tetrahedral oxygen atom with nonbonding pairs of electrons occupying two of the four sp3 hybrid orbitals. Secondary alcohols are easily oxidized without breaking carbon-carbon bonds only as far as the ketone stage. No further oxidation is seen except under very stringent conditions.Computed Properties of C40H26O2

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Alcohol – Wikipedia,
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Development of chiral catalysts by asymmetric activation for highly enantioselective diethylzinc addition to imines was written by Zhang, Hai-Le;Liu, Hua;Cui, Xin;Mi, Ai-Qiao;Jiang, Yao-Zhong;Gong, Liu-Zhu. And the article was included in Synlett in 2005.Reference of 851615-07-1 The following contents are mentioned in the article:

Based on the asym. activation concept, a library of chiral zinc complexes formed in situ by the combination of diimines derived from chiral 1,2-diphenyl-ethanene-1,2-diamine, BINOL derivatives, and diethylzinc are evaluated in the asym. addition of diethylzinc to N-acylimines. In the presence of 10 mol% catalyst I high enantioselectivities and yields were provided for a wide range of aromatic imines in 1,2-dichloroethane at -25 °C. This study involved multiple reactions and reactants, such as (R)-[1,3′:1′,1”:3”,1”’-Quaternaphthalene]-2′,2”-diol (cas: 851615-07-1Reference of 851615-07-1).

(R)-[1,3′:1′,1”:3”,1”’-Quaternaphthalene]-2′,2”-diol (cas: 851615-07-1) belongs to alcohols. Alcohols are weak acids. The most acidic simple alcohols (methanol and ethanol) are about as acidic as water, and most other alcohols are somewhat less acidic. Under carefully controlled conditions, simple alcohols can undergo intermolecular dehydration to give ethers. This reaction is effective only with methanol, ethanol, and other simple primary alcohols.Reference of 851615-07-1

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Alcohol – Wikipedia,
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Synthesis and Structural Aspects of N-Triflylphosphoramides and Their Calcium Salts-Highly Acidic and Effective Bronsted Acids was written by Rueping, Magnus;Nachtsheim, Boris J.;Koenigs, Rene M.;Ieawsuwan, Winai. And the article was included in Chemistry – A European Journal in 2010.Reference of 851615-07-1 The following contents are mentioned in the article:

Recently, 1,1′-bi-2-naphthol (BINOL)-based N-triflylphosphoramides emerged as a new class of potent Bronsted acid catalysts. In this paper we describe the efficient synthesis of various BINOL-based N-triflylphosphoramides, e.g. I [Ar = 1-naphthyl, 2-naphthyl, Ph, etc.], and their calcium salts. Furthermore, X-ray crystal structure anal. combined with energy-dispersive X-ray spectroscopy (EDX) measurements confirmed that the synthesized chiral N-triflylphosphoramides are highly acidic metal-free catalysts. This study involved multiple reactions and reactants, such as (R)-[1,3′:1′,1”:3”,1”’-Quaternaphthalene]-2′,2”-diol (cas: 851615-07-1Reference of 851615-07-1).

(R)-[1,3′:1′,1”:3”,1”’-Quaternaphthalene]-2′,2”-diol (cas: 851615-07-1) belongs to alcohols. Because alcohols are easily synthesized and easily transformed into other compounds, they serve as important intermediates in organic synthesis. Secondary alcohols are easily oxidized without breaking carbon-carbon bonds only as far as the ketone stage. No further oxidation is seen except under very stringent conditions.Reference of 851615-07-1

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Rapid Synthesis of 3,3′ Bis-Arylated BINOL Derivatives Using a C-H Borylation in Situ Suzuki-Miyaura Coupling Sequence was written by Ahmed, Ijaz;Clark, Daniel A.. And the article was included in Organic Letters in 2014.Product Details of 851615-07-1 The following contents are mentioned in the article:

The increased interest in BINOL derived catalysts for asym. transformations has encouraged us to disclose a rapid and scalable method of preparing 3,3′ bis-arylated BINOL derivatives 1 using a one-pot CH borylation/Suzuki-Miyaura coupling sequence. The use of an aldehyde additive was found to be crucial to the success of this in situ tandem approach. This method was applied to the preparation of 10 BINOL derivatives, each completed within 24 h. Notably, this approach requires only a single purification step. This study involved multiple reactions and reactants, such as (R)-[1,3′:1′,1”:3”,1”’-Quaternaphthalene]-2′,2”-diol (cas: 851615-07-1Product Details of 851615-07-1).

(R)-[1,3′:1′,1”:3”,1”’-Quaternaphthalene]-2′,2”-diol (cas: 851615-07-1) belongs to alcohols. Similar to water, an alcohol can be pictured as having an sp3 hybridized tetrahedral oxygen atom with nonbonding pairs of electrons occupying two of the four sp3 hybrid orbitals. Grignard and organolithium reagents are powerful tools for organic synthesis, and the most common products of their reactions are alcohols.Product Details of 851615-07-1

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Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Asymmetric Magnesium-Catalyzed Hydroboration by Metal-Ligand Cooperative Catalysis was written by Falconnet, Alban;Magre, Marc;Maity, Bholanath;Cavallo, Luigi;Rueping, Magnus. And the article was included in Angewandte Chemie, International Edition in 2019.Electric Literature of C40H26O2 The following contents are mentioned in the article:

Asym. catalysis with readily available, cheap, and nontoxic alk. earth metal catalysts represents a sustainable alternative to conventional synthesis methodologies. In this context, the authors describe the development of a 1st Mg(II)-catalyzed enantioselective hydroboration providing the products with excellent yields and enantioselectivities. NMR spectroscopy studies and DFT calculations provide insights into the reaction mechanism and the origin of the enantioselectivity which can be explained by a metal-ligand cooperative catalysis pathway involving a noninnocent ligand. This study involved multiple reactions and reactants, such as (R)-[1,3′:1′,1”:3”,1”’-Quaternaphthalene]-2′,2”-diol (cas: 851615-07-1Electric Literature of C40H26O2).

(R)-[1,3′:1′,1”:3”,1”’-Quaternaphthalene]-2′,2”-diol (cas: 851615-07-1) belongs to alcohols. Alkyl halides are often synthesized from alcohols, in effect substituting a halogen atom for the hydroxyl group. Tertiary alcohols cannot be oxidized at all without breaking carbon-carbon bonds, whereas primary alcohols can be oxidized to aldehydes or further oxidized to carboxylic acids.Electric Literature of C40H26O2

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Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Enantioselective Palladium-Catalyzed [3C + 2C] and [4C + 3C] Intramolecular Cycloadditions of Alkylidenecyclopropanes was written by Verdugo, Felipe;Villarino, Lara;Duran, Juan;Gulias, Moises;Mascarenas, Jose L.;Lopez, Fernando. And the article was included in ACS Catalysis in 2018.Product Details of 851615-07-1 The following contents are mentioned in the article:

We report a highly enantioselective [3C + 2C] intramol. cycloaddition of alkylidenecyclopropanes (ACPs) and alkenes. The best results are obtained by using sterically demanding chiral phosphoramidite ligands derived from Vapol. Moreover, we also show that related, but less bulky, phosphoramidites can also lead to very effective [4C + 3C] cycloadditions when dienes, instead of alkenes, are used as reacting partners. The reactions provide a practical, simple, and selective access to optically active, synthetically appealing 5,5- and 5,7-bicyclic systems. This study involved multiple reactions and reactants, such as (R)-[1,3′:1′,1”:3”,1”’-Quaternaphthalene]-2′,2”-diol (cas: 851615-07-1Product Details of 851615-07-1).

(R)-[1,3′:1′,1”:3”,1”’-Quaternaphthalene]-2′,2”-diol (cas: 851615-07-1) belongs to alcohols. Alcohols are among the most common organic compounds. They are used as sweeteners and in making perfumes, are valuable intermediates in the synthesis of other compounds, and are among the most abundantly produced organic chemicals in industry. Secondary alcohols are easily oxidized without breaking carbon-carbon bonds only as far as the ketone stage. No further oxidation is seen except under very stringent conditions.Product Details of 851615-07-1

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Chiral Counteranion-Directed Catalytic Asymmetric Methylene Migration Reaction of Ene-Aldimines was written by Momiyama, Norie;Jongwohan, Chanantida;Ohtsuka, Naoya;Chaibuth, Pawittra;Fujinami, Takeshi;Adachi, Kiyohiro;Suzuki, Toshiyasu. And the article was included in Journal of Organic Chemistry in 2022.Recommanded Product: (R)-[1,3′:1′,1”:3”,1”’-Quaternaphthalene]-2′,2”-diol The following contents are mentioned in the article:

A catalytic asym. methylene migration reaction of ene-aldimines directed by chiral counteranions was developed, with the optimal catalyst identified as phenanthryl-substituted (R)-BINOL phosphate. Control experiments and d. functional theory computations reveal the importance of the 2-hydroxy group of the ene-aldimine and attractive (e.g., OH···O, CH···O, CH···π, and π#183;··π) interactions for high enantioselectivity (up to 74% ee). The results contribute to the design of asym. catalysis for the rearrangement of highly reactive iminium intermediates. This study involved multiple reactions and reactants, such as (R)-[1,3′:1′,1”:3”,1”’-Quaternaphthalene]-2′,2”-diol (cas: 851615-07-1Recommanded Product: (R)-[1,3′:1′,1”:3”,1”’-Quaternaphthalene]-2′,2”-diol).

(R)-[1,3′:1′,1”:3”,1”’-Quaternaphthalene]-2′,2”-diol (cas: 851615-07-1) belongs to alcohols. Because alcohols are easily synthesized and easily transformed into other compounds, they serve as important intermediates in organic synthesis. Grignard and organolithium reagents are powerful tools for organic synthesis, and the most common products of their reactions are alcohols.Recommanded Product: (R)-[1,3′:1′,1”:3”,1”’-Quaternaphthalene]-2′,2”-diol

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Preparation of a new chiral stationary phase based on (2S,3S)-O,O’-bis-(10-undecenoyl)-N,N’-bis-(3,5-dinitrobenzoyl)-2,3-diamino-1,4-butanediol and its application for the liquid chromatographic resolution of enantiomers was written by Hyun, Myung Ho;Boo, Chang Jin;Choi, Hee Jung;Kim, Yun Kyoung;Kang, Bu Sung;Ha, Hyun Ju;Choi, Min Ki;Tan, Guanghui. And the article was included in Bulletin of the Korean Chemical Society in 2006.HPLC of Formula: 851615-07-1 The following contents are mentioned in the article:

A new liquid chromatog. chiral stationary phase based on (2S,3S)-O,O’-bis-(10-undecenoyl)-N,N’-bis-(3,5-dinitrobenzoyl)-2,3-diamino-1,4-butanediol was prepared starting from (2R,3R)-1,4-bis(benzyloxy)-2,3-butanediol. The new chiral stationary phase was applied to the resolution of racemic anilide derivatives of N-acetyl-α-amino acids, 1,1′-bi-2-naphthol and 3,3′-diaryl-1,1′-bi-2-naphthols. It was also applied to the resolution of some chiral drugs including bendroflumethiazide, naproxen and alminoprofen. In every case, the chiral recognition efficiency of the new CSP was quite excellent. This study involved multiple reactions and reactants, such as (R)-[1,3′:1′,1”:3”,1”’-Quaternaphthalene]-2′,2”-diol (cas: 851615-07-1HPLC of Formula: 851615-07-1).

(R)-[1,3′:1′,1”:3”,1”’-Quaternaphthalene]-2′,2”-diol (cas: 851615-07-1) belongs to alcohols. Because alcohols are easily synthesized and easily transformed into other compounds, they serve as important intermediates in organic synthesis. Secondary alcohols are easily oxidized without breaking carbon-carbon bonds only as far as the ketone stage. No further oxidation is seen except under very stringent conditions.HPLC of Formula: 851615-07-1

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts