New downstream synthetic route of 83811-73-8

While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 83811-73-8, (4-Phenylcyclohexyl)methanol.

Application of 83811-73-8, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 83811-73-8, name is (4-Phenylcyclohexyl)methanol. This compound has unique chemical properties. The synthetic route is as follows.

Second step Compound (III) (50 g, 0.268 mol) was dissolved in dry pyridine (110 ml) and cooled to 5 C. or lower. To this solution was dropwise added a solution of p-toluenesulfonic chloride (50.1 g, 0.263 mol) dissolved in dry toluene (70 ml), through a dropping funnel in small portions so that the reaction temperature could not exceed 10 C. After completion of the addition, the cooling bath was removed and agitation was carried out at room temperature for 4 hours, followed by adding water (100 ml) and toluene (300 ml) to extract the resulting product, washing the toluene-extraction liquid twice with 6N-HCl (100 ml), then once with water (200 ml), further twice with 2N aqueous solution of NaOH (100 ml), and 4 times with water (200 ml), distilling off the solvent, recrystallizing the residue from toluene (90 ml), filtering off and drying to obtain p-toluenesulfonic acid trans-4-phenylcyclohexyl methyl ester (IV) (77.0 g). M.P. 108.0~108.7 C.

While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 83811-73-8, (4-Phenylcyclohexyl)methanol.

Reference:
Patent; Chisso Corporation; US4522741; (1985); A;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts