Category: 80-09-1

Abellan, Alicia published the artcileIn utero exposure to bisphenols and asthma, wheeze, and lung function in school-age children: a prospective meta-analysis of 8 European birth cohorts, Related Products of alcohols-buliding-blocks, the publication is Environment International (2022), 107178, database is CAplus and MEDLINE.

In utero exposure to bisphenols, widely used in consumer products, may alter lung development and increase the risk of respiratory morbidity in the offspring. However, evidence is scarce and mostly focused on bisphenol A (BPA) only. To examine the associations of in utero exposure to BPA, bisphenol F (BPF), and bisphenol S (BPS) with asthma, wheeze, and lung function in school-age children, and whether these associations differ by sex. We included 3,007 mother-child pairs from eight European birth cohorts. Bisphenol concentrations were determined in maternal urine samples collected during pregnancy (1999-2010). Between 7 and 11 years of age, current asthma and wheeze were assessed from questionnaires and lung function by spirometry. Wheezing patterns were constructed from questionnaires from early to mid-childhood. We performed adjusted random-effects meta-anal. on individual participant data. Exposure to BPA was prevalent with 90% of maternal samples containing concentrations above detection limits. BPF and BPS were found in 27% and 49% of samples. In utero exposure to BPA was associated with higher odds of current asthma (OR = 1.13, 95% CI = 1.01, 1.27) and wheeze (OR = 1.14, 95% CI = 1.01, 1.30) (p-interaction sex = 0.01) among girls, but not with wheezing patterns nor lung function neither in overall nor among boys. We observed inconsistent associations of BPF and BPS with the respiratory outcomes assessed in overall and sex-stratified analyses. This study suggests that in utero BPA exposure may be associated with higher odds of asthma and wheeze among school-age girls.

Environment International published new progress about 80-09-1. 80-09-1 belongs to alcohols-buliding-blocks, auxiliary class Ploymers, name is 4,4′-Sulfonyldiphenol, and the molecular formula is C12H10O4S, Related Products of alcohols-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Chen, Li published the artcileDeveloping the large-area manganese-based catalytic ceramic membrane for peroxymonosulfate activation: Applications in degradation of endocrine disrupting compounds in drinking water, Quality Control of 80-09-1, the publication is Journal of Membrane Science (2022), 120602, database is CAplus.

Endocrine disrupting compounds (EDCs) in the aquatic systems are of growing concerns that could undermine drinking water safety. In this study, manganese (III) oxide (Mn2O3) based catalytic ceramic membrane (CCM) was developed for the activation of peroxymonosulfate (PMS), and its applicability has been tested in degrading the ten different EDCs (including bisphenol analogs (BPs)) in drinking water. The CCMs were synthesized at different calcination temperatures i.e., 850, 950, and 1150°C. Optimal performance of CCMs/PMS was achieved at a higher degree of calcination. The CCMs/PMS has shown a potential to effectively degrade the EDCs at higher concentrations (mg/L) to trace levels (ng/L). The CCMs/PMS system adopted a non-radical pathway of degrading the EDCs through the extensive generation of singlet oxygen (1O2), as confirmed using quenching experiments and ESR (EPR) spectroscopy. 1O2-based oxidation process showed special selectivity for the decontamination of phenols and bisphenols. The long-term performance of CCMs/PMS showed good stability in degradation of the EDCs in drinking water, also with efficient mineralization (TOC removal >55%) and negligible release of Mn (0.004 wt%Mn/min). CCMs/PMS system also showed high potential in improving water quality by reducing the disinfection byproducts (DBPs) formation potential, highest recorded for bromodichloromethane (CHCl2Br, 100%) and lowest for dichloroacetic acids (TCAA, ∼50%). The study provided a highly efficient catalytic ceramic membrane based advanced oxidation process (AOPs) for effective degradation multiple of EDCs in drinking water, and the findings of this work can be a baseline for full-scale water treatment applications.

Journal of Membrane Science published new progress about 80-09-1. 80-09-1 belongs to alcohols-buliding-blocks, auxiliary class Ploymers, name is 4,4′-Sulfonyldiphenol, and the molecular formula is C12H10O4S, Quality Control of 80-09-1.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Melough, Melissa M. published the artcileDiet quality and exposure to endocrine-disrupting chemicals among US adults, Quality Control of 80-09-1, the publication is Environmental Research (2022), 113049, database is CAplus and MEDLINE.

Human exposure to endocrine-disrupting chems. (EDCs) may increase risk for chronic disease. Diet is a significant source of EDC exposure, yet healthy diets recommended for chronic disease prevention have not been thoroughly examined for associations with EDC exposure. Using data from the National Health and Nutrition Examination Survey 2013-2016, we examined associations of dietary patterns with exposure to non-persistent EDCs potentially consumed through diet. EDCs were measured in spot urine samples. Diet was assessed using 24-h recalls. Multivariable linear regression was used to examine associations of three healthy diet scores [Healthy Eating Index (HEI), relative Mediterranean Diet (rMED), and Dietary Approaches to Stop Hypertension] and fast-food consumption with EDCs. In fully adjusted models, no diet was associated with exposure to the bisphenols, phthalates, or polycyclic aromatic hydrocarbons examined A 1-point increase in rMED (of 18 possible points) was associated with 2.7% (95% CI: 1.7%, 3.8%) greater urinary nitrate. A 10-point increase in HEI (of 100 possible points) was associated with 5.3% (95% CI: 2.8%, 7.9%) greater nitrate and 6.8% (95% CI: 4.5%, 9.2%) greater perchlorate. Because perchlorate and nitrate can disrupt thyroid hormone production, we conducted an exploratory anal. to examine whether these chems. mediate an association between diet and thyroid hormones. A 10-point increase in HEI was associated with 0.6% reduced serum total thyroxine (95% CI: 1.7%, 0.5%) among all adults, with 57.5% of the effect explained by perchlorate. Nitrate mediated an association of rMED with modestly reduced total triiodothyronine among females. Most EDCs examined had no association with the diets evaluated, indicating that recommended healthy diets were not protective against EDC exposures. As observed with two thyroid antagonists, some recommended diets may increase EDC exposures and related adverse health outcomes. Addnl. work should identify effective food production and processing practices to reduce dietary exposures to potentially harmful EDCs.

Environmental Research published new progress about 80-09-1. 80-09-1 belongs to alcohols-buliding-blocks, auxiliary class Ploymers, name is 4,4′-Sulfonyldiphenol, and the molecular formula is C12H10O4S, Quality Control of 80-09-1.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Ding, Haohao published the artcileA phosphorus/sulfur-containing compound toward simultaneously endowing epoxy resin with good flame retardancy and high transparency, Computed Properties of 80-09-1, the publication is Journal of Applied Polymer Science (2022), 139(26), e52431, database is CAplus.

A phosphorus/sulfur-containing compound (sulfonylbis(3,1-phenylene) bis(diphenyl-phosphinate), named as SBPDPP) is designed and synthesized by nucleophilic substitution reaction between diphenylphosphinyl chloride and 4,4-dihydroxydiphenylsulfone, and its chem. structure is verified by Fourier transform IR, ¹H and ³¹P NMR. The incorporation of SBPDPP accelerates the curing process but decreases the glass transition temperature and the crosslinking d. of the epoxy resin (EP). The cured EP with 6 wt% SBPDPP passes UL-94 V0 rating and gives limited oxygen index value of 38.8%, meanwhile maintaining 90% of the transmittance of the pure EP. Its peak heat release rate, total heat release, total smoke production, and total smoke rate are reduced by 40.8%, 42.0%, 26.3%, and 21.9% in comparison with the pure EP, demonstrating that the SBPDPP improved simultaneously the fire safety and smoke suppression. The comprehensive anal. of the char residues after cone calorimeter test and the volatile gasses during the pyrolysis demonstrates that the SBPDPP exerted dual flame retardant effect in the gas and condensed phase. The cured FREPs have promising applications that requiring flame retardancy and maintaining transparency.

Journal of Applied Polymer Science published new progress about 80-09-1. 80-09-1 belongs to alcohols-buliding-blocks, auxiliary class Ploymers, name is 4,4′-Sulfonyldiphenol, and the molecular formula is C12H10O4S, Computed Properties of 80-09-1.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Sun, Ruiting published the artcilePeanut shells-derived biochars as adsorbents for the pipette-tip solid-phase extraction of endocrine-disrupting phenols in water, milk and beverage, Formula: C12H10O4S, the publication is Journal of Chromatography A (2022), 463101, database is CAplus and MEDLINE.

In the present work, a type of biochar materials derived from carbonizing peanut shells were obtained and employed as the adsorbents of pipet-tip solid-phase extraction (PT-SPE) for the enrichment and determination of six endocrine-disrupting phenols (EDPs) in combination with high-performance liquid chromatog. equipped with UV detector (HPLC-UV). Abundant aliphatic and aromatic carbon structures and functional groups from polar heteroatoms (N, O, S) were distributed in the low-cost and eco-friendly peanut shells-derived biochar materials and were favorable for the enrichment of target EDPs. Moreover, the theor. calculation based on d. functional theory (DFT) proved that the effective enrichment of EDPs in aqueous samples benefited from the effective adsorption on the peanut shells-derived biochar materials. The exptl. factors influencing the extraction efficiency were investigated, including adsorbent amount, aspirating/dispensing cycles, the type of elution solvent and elution times, salt addition, sample solution pH and type and volume of washing solvent. Under the optimal conditions, the proposed PT-SPE method exhibited good linear relationship (R2 > 0.993) in the range of 0.5-400μg/L and low limits of detections (LODs) from 0.25 to 2.5μg/L, as well as good precision and accuracy with relative standard deviations (RSDs) of 0.3%-13.2% and recoveries of 83.5%-117.1%. Finally, the biochars-based miniaturized pretreatment method was employed for the determination of six EDPs in bottled water, milk, tea beverage and disposal plastic bag soaked solution with recoveries from 77.5% to 116.5%.

Journal of Chromatography A published new progress about 80-09-1. 80-09-1 belongs to alcohols-buliding-blocks, auxiliary class Ploymers, name is 4,4′-Sulfonyldiphenol, and the molecular formula is C16H24BF4Ir, Formula: C12H10O4S.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Vaccher, Vincent published the artcileEuropean interlaboratory comparison investigations (ICI) and external quality assurance schemes (EQUAS) for the analysis of bisphenol A, S and F in human urine: Results from the HBM4EU project, Related Products of alcohols-buliding-blocks, the publication is Environmental Research (2022), 112933, database is CAplus and MEDLINE.

The Human Biomonitoring for Europe initiative (HBM4EU) aims to study the exposure of citizens to chems. and potentially associated health effects. One objective of this project has been to build a network of laboratories able to answer to the requirements of European human biomonitoring studies. Within the HBM4EU quality assurance and quality control scheme (QA/QC), a number of interlaboratory comparison investigations (ICIs) and external quality assurance schemes (EQUASs) were organized to ensure data consistency, comparability and reliability. Bisphenols are among the prioritized substance groups in HBM4EU, including bisphenol A (BPA), bisphenol S (BPS) and bisphenol F (BPF) in human urine. In four rounds of ICI/EQUAS, two target concentration levels were considered, related to around P25 and P95 of the typical exposure distribution observed in the European general population. Special attention was paid to the conjugated phase II metabolites known to be most dominant in samples of environmentally exposed individuals, through the anal. of both native samples and samples fortified with glucuronide forms. For the low level, the average percentage of satisfactory results across the four rounds was 83% for BPA, 71% for BPS and 62% for BPF. For the high level, the percentages of satisfactory results increased to 93% for BPA, 89% for BPS and 86% for BPF. 24 out of 32 participating laboratories (75%) were approved for the analyses of BPA in the HBM4EU project according to the defined criterion of Z-scores for both low and high concentration levels in at least two ICI/EQUAS rounds. For BPS and BPF, the number of qualified laboratories was 18 out of 27 (67%) and 13 out of 28 (46%), resp. These results demonstrate a strong anal. capability for BPA and BPS in Europe, while improvements may be needed for BPF.

Environmental Research published new progress about 80-09-1. 80-09-1 belongs to alcohols-buliding-blocks, auxiliary class Ploymers, name is 4,4′-Sulfonyldiphenol, and the molecular formula is C28H52N2O2S2Sn2, Related Products of alcohols-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Xu, Katherine J. published the artcileBisphenol S induces Agrp expression through GPER1 activation and alters transcription factor expression in immortalized hypothalamic neurons: A mechanism distinct from BPA-induced upregulation, HPLC of Formula: 80-09-1, the publication is Molecular and Cellular Endocrinology (2022), 111630, database is CAplus and MEDLINE.

The increasing prevalence of obesity around the world has brought concern upon ubiquitously present obesogenic environmental compounds, such as bisphenol A (BPA). Increasingly tightened regulations on the industrial use of BPA have prompted a transition to a structurally similar alternative, bisphenol S (BPS). BPS displays endocrine-disrupting behaviors similar to those of BPA and increases body weight, food intake and the hypothalamic expression of Agrp in vivo. However, the mechanisms behind this deleterious effect are unclear. Here, we report an increase in the mRNA level of Agrp at 4 h following BPS treatment in immortalized murine hypothalamic cell lines of embryonic and adult origin (mHypoE-41, mHypoA-59). BPS-induced changes in the expression of transcription factors and estrogen receptors that occurred concurrently with Agrp upregulation demonstrated similarities to BPA-induced changes, however, there were also changes that were unique to BPS. Specifically, while Chop, Atf3, Atf4, Atf6, Klf4, and Creb1 were upregulated and Gper1 was downregulated by both BPA and BPS, Esr1 mRNA levels were upregulated and Foxo1 and Stat3 levels remained unchanged by BPS. Finally, inhibition of GPER1 by G15 prevented BPS-mediated Agrp upregulation, independent of Atf3 and Klf4 upregulation. Overall, our results demonstrate the ability of BPS to increase Agrp mRNA expression through GPER1 signaling and to alter transcription factor expression in hypothalamic neurons, further elucidating the endocrine-disrupting potential of this alternative industrial chem.

Molecular and Cellular Endocrinology published new progress about 80-09-1. 80-09-1 belongs to alcohols-buliding-blocks, auxiliary class Ploymers, name is 4,4′-Sulfonyldiphenol, and the molecular formula is C8H6ClF3, HPLC of Formula: 80-09-1.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Ao, Junjie published the artcileBisphenol S exposure induces intestinal inflammation: An integrated metabolomic and transcriptomic study, SDS of cas: 80-09-1, the publication is Chemosphere (2022), 133510, database is CAplus and MEDLINE.

As a typical substitute for bisphenol A (BPA), bisphenol S (BPS) is raising concerns due to the potential adverse effects on human health. Limit evidence is available to understand the toxicity of BPS to the digestive system, especially for intestine. In this study, we aimed to investigate the potential effects and underlying mechanisms of BPS exposure on human colon mucosal epithelial cells (NCM460). Our results showed that BPS exposure significantly increased the production of pro-inflammatory cytokines, including tumor necrosis factor-α (TNF-α), interferon-γ (IFN-γ) and interleukin-17A (IL-17A). The tight junctions of the cells has been destroyed by BPS exposure, which was characterized by a down-regulation of the tight junction proteins (Claudin1 and zonula occluden 1 (ZO1)). A multi-omics study explored the underlying mechanisms based on the metabolomic and transcriptomic responses. A variety of neurotransmitters increased significantly after exposure to BPS. The top enriched pathway was “glutamatergic synapse”;, which was activated by BPS exposure, resulting in the up-regulation of L-glutamine. Links were observed among the altered metabolites, genes and cytokines. Our results indicate that exposure to BPS may disturb the balance of gut-brain axis, leading to the production of inflammatory cytokines and the destruction of tight junction in NCM460 cells. It provides new clue for the development of intestinal inflammation in terms of the environmental pollutants.

Chemosphere published new progress about 80-09-1. 80-09-1 belongs to alcohols-buliding-blocks, auxiliary class Ploymers, name is 4,4′-Sulfonyldiphenol, and the molecular formula is C12H10O4S, SDS of cas: 80-09-1.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Gao, Zhangshan published the artcileTesticular toxicity of bisphenol compounds: Homeostasis disruption of cholesterol/testosterone via PPARα activation, Recommanded Product: 4,4′-Sulfonyldiphenol, the publication is Science of the Total Environment (2022), 155628, database is CAplus and MEDLINE.

The widespread application of bisphenols (BPs) has made them ubiquitous in the environment. Although the side effects of bisphenol A (BPA) substitutes have received increasing attention, studies on their reproductive toxicity remain lacking. In this research, the effects of BPA and its substitutes, including bisphenol S (BPS), bisphenol F (BPF), and bisphenol AF (BPAF), on the male reproductive system were evaluated. Results proved that these BPs disturbed germ cell proliferation, induced germ cell apoptosis, and perturbed sperm physiologies and spermatogenesis, which resulted from the disruption of testosterone (T) biosynthesis in Leydig cells (LCs). Importantly, in vitro and in vivo studies indicated that the exhausted cholesterol in LCs accounted for the reduced T production Furthermore, the knockdown of peroxisome proliferator-activated receptor alpha (PPARα) remarkably ameliorated the downregulation of cholesterogenesis-related genes (i.e., Hmgcs1, Hmgcr, and Srebf2), indicating that PPARα played a critical role in BPs-induced testicular dysfunction. Overall, our studies indicated that BPS, BPF, and BPAF could induce testicular toxic effects similar to that of BPA, which were associated with the PPARα pathway.

Science of the Total Environment published new progress about 80-09-1. 80-09-1 belongs to alcohols-buliding-blocks, auxiliary class Ploymers, name is 4,4′-Sulfonyldiphenol, and the molecular formula is C12H10O4S, Recommanded Product: 4,4′-Sulfonyldiphenol.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts

Zhou, Yi published the artcileEfficient Oxidation of Paracetamol Triggered by Molecular-Oxygen Activation at β-Cyclodextrin-Modified Titanate Nanotubes, Formula: C12H10O4S, the publication is Chemistry – An Asian Journal (2022), 17(13), e202200352, database is CAplus and MEDLINE.

Titanate nanotubes (TNTs) were coated with a cyclic oligosaccharide (carboxymethyl-β-cyclodextrin, CM-β-CD) to obtain a photocatalyst (CM-β-CD-TNT) for efficiently activating mol. oxygen and removing the target contaminant. The hydrophobic cavity and the large sp. surface area of the photocatalyst provide abundant active sites for activating mol. oxygen. The free radical capture experiment and quenching experiment showed that cyclodextrin could facilitate adsorption and activation of mol. oxygen to produce O₂.-. Therefore, compared with the pristine TNT, CM-β-CD-TNT accelerated the oxidation efficiency of paracetamol (APAP) by 3.4 times. Moreover, the ring cleavage reaction induced by CM-β-CD-TNT effectively reduced the acute toxicity of wastewater containing APAP. Furthermore, 100% of bisphenol A (BPA), bisphenol S (BPS), phenol, 2,4-dichlorophen (2,4-DCP), and carbamazepine (CBZ) were degraded by CM-β-CD-TNT after 2.5 h UV light irradiation This strategy provides a new dimension for the advanced treatment of organic wastewater by organic macrocyclic mol.-modified materials.

Chemistry – An Asian Journal published new progress about 80-09-1. 80-09-1 belongs to alcohols-buliding-blocks, auxiliary class Ploymers, name is 4,4′-Sulfonyldiphenol, and the molecular formula is C4H5NS2, Formula: C12H10O4S.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts